Suprahepatic vein oxygen tension in alcoholics with severe and mild liver damage.

Abstract:

:We measured suprahepatic vein and arterial partial oxygen pressure in 35 alcoholics with severe (N = 7) or mild (N = 28) histological liver damage and without evidence of clinical liver failure. The suprahepatic vein was punctured with a fine needle, using a percutaneous approach. Suprahepatic vein partial oxygen pressure was lower and arterial-suprahepatic gradient higher in alcoholics with severe liver damage compared to those with mild damage (35.1 +/- 1.7 vs 44.1 +/- 2.1 and 58.9 +/- 3.7 vs 45.9 +/- 2.4 mm Hg, respectively; P < 0.001). Suprahepatic puncture was well tolerated and devoid of complications. It is concluded that alcoholics with severe liver damage have lower oxygen tensions in the suprahepatic vein, a phenomenon that supports the hypoxic theory of alcoholic liver disease.

journal_name

Dig Dis Sci

authors

Bunout D,Moya P,de la Maza MP,Petermann M,Iturriaga H,Hirsch S

doi

10.1007/BF02065531

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

1243-5

issue

6

eissn

0163-2116

issn

1573-2568

journal_volume

40

pub_type

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