Abstract:
:A 68-year-old woman developed exfoliative dermatitis while taking cimetidine for gastritis. She had no history of previous drug reactions, allergies, or skin disorders and had taken no other medications for three months. Although cimetidine is a relatively safe drug, severe reactions such as exfoliative dermatitis can occur.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Yantis PL,Bridges ME,Pittman FEdoi
10.1007/BF01312737subject
Has Abstractpub_date
1980-01-01 00:00:00pages
73-4issue
1eissn
0163-2116issn
1573-2568journal_volume
25pub_type
杂志文章abstract::Studies have shown a promoting effect of food on small intestinal absorption. Casein hydrolysate seems be more effective in increasing of D-xylose absorption in dogs than the whole protein and lactulose. The purpose this study was to analyze the effect of groups of peptides derived from casein hydrolysate on the absor...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1005439525762
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:The colon is partly controlled by myenteric and submucosal plexuses, which respond to stress and lead to some gastrointestinal disorders. These plexuses play roles in irritable bowel syndrome. Patients suffering from this syndrome can be treated with some antidepressants, including sertraline and nortriptyli...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-019-05600-y
更新日期:2019-09-01 00:00:00
abstract::Trichinella spiralis infection in rodents is a well-known model of intestinal inflammation associated with hypermotility and hypersecretion. Our aim was to use this experimental model to elucidate if iNOS was involved in the development of gastrointestinal hypermotility. Rats infected with Trichinella spiralis were tr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1023796108391
更新日期:2003-06-01 00:00:00
abstract::The Wnt/beta-catenin pathway has been proposed as promoting intestinal stem cell division. Wnt ligands activate cytoplasmic beta-catenin and increase nuclear translocation of beta-catenin that binds to the Tcf-4 transcription factor. The aim of this study was to investigate beta-catenin expression in the stem cell reg...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-006-9200-7
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Postmenopausal women have a higher risk of nonalcoholic steatohepatitis (NASH) along with an increase in age, and vitamin D deficiency occurs in some patients with NASH. AIM:We performed ovariectomy (OVX) surgery on female mice to mimic menopause, fed them a choline-deficient high-fat (CDHF) diet to induce ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-019-05560-3
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Total parenteral nutrition (TPN), a necessary treatment for patients who cannot receive enteral nutrition, is associated with infectious complications due in part to a loss of intestinal epithelial barrier function (EBF). Using a mouse model of TPN, with enteral nutrient deprivation, we previously demonstrat...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3991-3
更新日期:2016-06-01 00:00:00
abstract::In recent years, three-dimensional (3-D) printing technology has become a standard tool that is used in several medical applications such as education, surgical training simulation and planning, and doctor-patient communication. Although liver surgery is ideally complemented by the use of preoperative 3-D-printed mode...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-020-06326-y
更新日期:2020-08-01 00:00:00
abstract::The development of experimental cholecystitis produced by lysophosphatidylcholine is associated with reversal of the normal absorptive characteristics of gallbladder mucosa, resulting in the intraluminal accumulation of water, glycoprotein, and protein. The purpose of the present study was to attempt to ascertain if t...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02064215
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Corticotropin-releasing factor (CRF) peptides exert profound effects on the secretomotor function of the gastrointestinal tract. Nevertheless, despite the presence of CRF peptides and receptors in colonic tissue, their influence on colonic blood flow (CBF) is unknown. AIM:To determine the effect and mechani...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3579-y
更新日期:2015-04-01 00:00:00
abstract::We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01538066
更新日期:1989-09-01 00:00:00
abstract::The wound-healing property of Preparation-H, a widely used over-the-counter hemorrhoidal product was investigated in a randomized, controlled, double-blind trial. Artificial ulcers were created in the rectum of 12 healthy male volunteers and the size of these ulcers followed until complete healing by visual examinatio...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
doi:10.1007/BF01318426
更新日期:1984-09-01 00:00:00
abstract::Multiple endoscopic biopsies were taken from 100 consecutive patients who had a macroscopically normal colon at colonoscopy. Of these, 78 were regarded as histologically normal; 13 cases of melanosis coli, 7 cases of intestinal spirochetosis, and 2 cases of collagenous colitis were identified. In no cases was there hi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296130
更新日期:1987-07-01 00:00:00
abstract::In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296773
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Recent data suggest the involvement of both the adaptive and the innate immune system in celiac disease (CD). However, little is known about the immune phenotype of children with CD and its alteration upon dietary intervention. AIMS:We characterized the prevalence of major interacting members of the adaptiv...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1363-6
更新日期:2011-03-01 00:00:00
abstract::The original version of the article unfortunately contained tagging error in first and family name of authors Ariella Bar-Gil Shitrit and Ami Ben Ya'acov. This has been corrected with this erratum. ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10620-018-5084-6
更新日期:2018-09-01 00:00:00
abstract::The oral intake of food is important for the observed compensatory hyperplasia in the remnant small intestine after resection but the molecular events governing this response are not known. Peptides, of molecular weight 4500 and 1000 daltons, present in the the proximal intestine for 96 hr after resection and mitogeni...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536635
更新日期:1988-01-01 00:00:00
abstract::We report a case of Pseudomonas aeruginosa liver abscesses following endoscopic retrograde cholangiopancreatography (ERCP) in a patient without evidence of biliary tract disease and of any known cause of hepatic infection. Computer tomography (CT) scan was the best method of diagnosis, allowing, through guided percuta...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297196
更新日期:1987-09-01 00:00:00
abstract::The study was undertaken to examine regional differences in the concentrations of five regulatory peptides in the human colonic mucosa. Biopsies were obtained during routine colonoscopy from 33 patients whose colonic mucosa was macroscopically and histologically normal. Regulatory peptides were extracted, and measured...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01537267
更新日期:1989-08-01 00:00:00
abstract::The aim of our prospective randomized study involving 100 patients was to investigate whether Doppler ultrasound can be used to select patients at risk for ulcer rebleeding. Ulcers in the Forrest group classified as having a visible vessel or a clot were treated prophylactically by injection with epinephrine solution....
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1023/a:1018877602113
更新日期:1997-07-01 00:00:00
abstract::The relationship between the GOT/GPT ratio in nonviral liver disorders and underlying physical condition and life-style were evaluated. The subjects were 12,808 male railway company workers who underwent an annual health checkup. Nonviral liver disorders were defined as elevated transaminases (GOT > 76 IU/liter or GPT...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1017959801493
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:Assessment and quantification of actual liver function is crucial in patients with chronic liver disease to monitor disease progression and predict individual prognosis. Mathematical models, such as model for end-stage liver disease, are used for risk stratification of patients with chronic liver disease but...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-014-3250-z
更新日期:2014-12-01 00:00:00
abstract::Recent data would limit indications for serum CEA measurement primarily to follow-up of resected colonic malignancy, yet physician attitude and usage patterns may lag far behind current findings. This discrepancy was investigated at our institution, where more than 1100 CEAs costing $71,000 are ordered each year. Of 4...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296746
更新日期:1982-04-01 00:00:00
abstract::The specificity of polymerase chain reaction monoclonality in the diagnosis of gastric lymphoma was prospectively evaluated. Gastric mucosal tissue from normal gastric mucosa (N = 13), benign gastric ulcers (N = 3), chronic Helicobacter pylori gastritis (N = 3), gastric mucosa-associated lymphoid tissue (N = 16), and ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018842002926
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND:Inflammatory bowel disease (IBD) is a heterogeneous collection of chronic inflammatory disorders of the digestive tract. Clinical, genetic, and pathological heterogeneity makes it increasingly difficult to translate efficacy studies into real-world practice. Our objective was to develop a comprehensive natur...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-016-4278-z
更新日期:2016-11-01 00:00:00
abstract::The main objective of our studies has been to optimize the effects of monoclonal antibodies (MAbs) and other immunosuppressive reagents to enhance organ graft survival. One such agent is OKT3, a MAb that is directed against the CD3 component of the human T-cell receptor (TCR) complex. Treatment of a rejection episode ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/BF02063942
更新日期:1995-01-01 00:00:00
abstract::Of 112 patients with peptic ulcer disease examined for oral carriage of Candida, 66 (59%) were carriers. Candida carriage was associated with blood group O (P < 0.05) and, independently, with nonsecretion of blood group antigens (P < 0.01). For each subject, the presence or absence of yeasts was found to be a constant...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308603
更新日期:1993-08-01 00:00:00
abstract:INTRODUCTION:A significant proportion of patients with Crohn's disease (CD) lose response to antibodies directed against tumor necrosis factor α (TNF). Prior TNF-antagonist failure is associated with lower rates of response to subsequent TNF-antagonist therapy. In patients failing two anti-TNF agents, a choice exists b...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1896-3
更新日期:2012-02-01 00:00:00
abstract::Idiopathic chronic constipation is a frequent and disabling symptom, but its pathophysiological grounds are still poorly understood. In particular, there is little knowledge about the relationships between distal (anorectal area) and proximal (colonic area) motor abnormalities in this condition, especially concerning ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02088064
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:The outcomes of infliximab dose escalation in ulcerative colitis (UC) have not been well evaluated. AIMS:To assess the short- and long-term outcomes of infliximab dose escalation in a cohort of patients with UC. METHODS:This was a multicenter, retrospective, cohort study. All consecutive UC patients who ha...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,多中心研究
doi:10.1007/s10620-015-3735-4
更新日期:2015-10-01 00:00:00
abstract::Since granulocyte elastase has been shown to be involved in the pathogenesis of gastric mucosal lesion formation induced by nonsteroidal antiinflammatory drugs, inhibition of granulocyte elastase release from neutrophils may be useful in the prevention of these lesions. The objective of this study was to determine whe...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00