Abstract:
:To determine whether abnormalities of the lymphocyte populations are associated with alcoholic liver disease, we have characterized the subpopulations of lymphocytes in 30 alcoholic patients with and without liver disease. Total T lymphocytes were decreased in patients with alcoholic hepatitis and alcoholic cirrhosis. However, T4 (helper) and T8 (suppressor/cytotoxic) cells and the T4 and T8 cell ratio were similar to the values in controls. In these patients, the sums of T4/T8 cells exceeded that of total T cells, an alteration apparently related to severe liver damage. Cells reacting with antisera to immunoglobulins (B lymphocytes) and to Dr determinants were also within the normal range. In contrast, NK/K (natural killer/killer) cells were increased in the group of patients with steatosis or without liver alteration. Increase of NK/K cells was not observed in patients who were abstinent from alcohol for a period of two weeks or more, suggesting that alcohol may have been responsible for the increase in this lymphocyte population.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Jovanovic R,Worner T,Lieber CS,Paronetto Fdoi
10.1007/BF01300696subject
Has Abstractpub_date
1986-02-01 00:00:00pages
125-30issue
2eissn
0163-2116issn
1573-2568journal_volume
31pub_type
杂志文章abstract::Ascites is more difficult to detect when only a small quantity is present. The aim of this pilot study was to determine the optimal bowel sound characteristics in order to distinguish no ascites from small-volume ascites by advanced processing of bowel sound wave patterns. This analysis results in the definition of th...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1024788428692
更新日期:2003-08-01 00:00:00
abstract::Sonic Hedgehog (Shh) signaling has been extensively studied for its role in developmental biology and cancer biology. The association between Shh and cancer development in general is well established but the functional role of Shh in the development and progression of gastric cancer specifically is largely unknown. Bo...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-010-1252-z
更新日期:2010-06-01 00:00:00
abstract:UNLABELLED:Recent evidence suggests that psychological factors may affect esophageal as well as intestinal motility. To study this further, we compared the psychological profiles of 20 irritable bowel patients and 20 patients with recurrent noncardiac chest pain associated with high-amplitude peristaltic contractions i...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01300697
更新日期:1986-02-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026605409557
更新日期:1998-11-01 00:00:00
abstract::The intrarectal administration of trinitrobenzene sulfonic acid in rats induces ulcerative colitis, which results in histological alterations of colonic mucosa, severe modification of the cellular antioxidant defense system, and enhanced production of inflammatory eicosanoids. This study evaluated the influence of dif...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026655311878
更新日期:1998-12-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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journal_title:Digestive diseases and sciences
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10620-006-3137-8
更新日期:2006-02-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-013-2957-6
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01537575
更新日期:1990-09-01 00:00:00
abstract::Alterations in insulin and glucagon levels might account for the plasma amino acid imbalance of cirrhotics. In order to verify this hypothesis we evaluated basal insulin, glucagon, branched-chain amino acids, aromatic amino acids, and free tryptophan in 13 controls and 37 cirrhotics divided on the basis of their menta...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01333703
更新日期:1979-08-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-012-2271-8
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01537100
更新日期:1989-10-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1005626622203
更新日期:2000-12-01 00:00:00
abstract::Systemic and splanchnic hemodynamics in experimental liver cirrhosis in rats induced by thioacetamide were evaluated by the radioactive microsphere method. Cardiac output and regional blood flow were measured in conscious and anesthetized control and cirrhotic rats. The conscious thioacetamide-treated rats had hyperdy...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01299895
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND AND AIM:To explore the CT signs which permit estimation of clinically severe portal hypertension (PH) [≥ 12 of hepatic vein pressure gradient (HVPG)]. METHODS:One-hundred and seven consecutive patients who underwent HVPG measurement in the PH group and 52 controls were included. The diameters of main portal...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-014-3149-8
更新日期:2014-09-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02064215
更新日期:1995-05-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-005-1590-4
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journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1023/a:1018851227051
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND AND AIMS:Current genetic research of nonalcoholic steatohepatitis (NASH) cirrhosis is limited by our ability to accurately identify cases on a large scale. Our objective was to develop and validate an electronic health record (EHR) algorithm to accurately identify cases of NASH cirrhosis in the EHR. METHODS...
journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-020-06388-y
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-005-2720-8
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-009-0837-x
更新日期:2010-04-01 00:00:00
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journal_title:Digestive diseases and sciences
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更新日期:2018-02-01 00:00:00
abstract::To evaluate pancreatic exocrine function in uremia, 25 patients undergoing regular hemodialysis without clinical evidence of pancreatic disease and 25 healthy control subjects were studied by fecal elastase 1 and chymotrypsin. Abdominal ultrasonography and measurement of serum lipase, calcium, phosphate, and parathorm...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026487807555
更新日期:2000-11-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-008-0404-x
更新日期:2009-04-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1012330626600
更新日期:2001-11-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01403843
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1708-9
更新日期:2011-10-01 00:00:00
abstract::The effect of ursodeoxycholic acid (UDCA) on bile lipid composition and bile acid kinetics was evaluated in seven cholesterol gallstone patients following one month of UDCA administration (12 mg/kg/day). UDCA administration induces a significant reduction in the cholesterol saturation index (SI). After UDCA treatment,...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01324739
更新日期:1979-02-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-020-06436-7
更新日期:2020-07-04 00:00:00