Abstract：
:Concentration and voltage dependence of unidirectional Mg fluxes across the rat colon ascendens were measured in a modified Ussing chamber. Mucosa (M) to serosa (S) Mg flux exhibits a cellular component, whereas SM flux is totally diffusive. At all the concentrations between 0.125 and 8 mmol/liter MS Mg transport is higher than the flux in the opposite direction, resulting in Mg absorption. In contrast to Mg, in Ca transport a cellular component is involved in both directions across the tissue, 1 alpha, 25-Dihydroxyvitamin D3 has no influence on the Mg transport. Mg (5 mmol/liter) remarkably decreases MS Ca flux and reduces Ca absorption by 70%. The parallel decrease in MS Ca flux with that of the simultaneously measured paracellular marker mannitol and the voltage clamp experiments reveal that Mg has no influence on cellular Ca transport but only reduces diffusive MS Ca flux, possibly by decreasing transepithelial fluid absorption. The experiments demonstrate that the colon ascendens of the rat is capable of absorbing Mg at rates comparable to that found for Ca. There is evidence that Mg and Ca are transported by separate cellular mechanisms. Diffusive movement across the paracellular route plays an important role on net transport of both earth alkali ions.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Karbach Udoi
10.1007/BF01536699subject
Has Abstractpub_date
1989-12-01 00:00:00pages
1825-31issue
12eissn
0163-2116issn
1573-2568journal_volume
34pub_type
杂志文章abstract：:Gastric antral vascular ectasia was endoscopically diagnosed in seven patients. Pathologic characteristics of this entity were defined retrospectively, by studying endoscopic pinch biopsy slides from these seven patients and antrectomy specimens from five patients. A scoring system was developed, and the seven patient...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01540274
更新日期：1989-06-01 00:00:00
abstract：:A discrepancy exists on the effects of somatostatin on the absorption of nutrients: in humans, absorption was found to be reduced, whereas in rats no effects were observed. However, intestinal absorption might be influenced by the transit rate of contents. This was not considered in previous studies. Therefore, we inv...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02091528
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND AND AIMS:Accumulating evidence has indicated that variations of mitochondrial DNA (mtDNA) content may affect the susceptibility to hepatocellular carcinoma (HCC). However, no study has been conducted to evaluate the association of circulating mtDNA content and the risk of liver cirrhosis, a leading cause of ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-3523-1
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:There is a large Barrett's esophagus patient population undergoing endoscopic surveillance. Methods to stratify patients into higher and lower risk groups may enable more varied surveillance intervals for patients with non-dysplastic Barrett's esophagus that could optimize use of endoscopy resources. OBJECT...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06483-0
更新日期：2020-07-20 00:00:00
abstract：BACKGROUND AND AIM:Atelectasis is one of the pulmonary complications associated with anesthesia. Little is known about atelectasis following endoscopic procedures under deep sedation. This study evaluated the frequency, risk factors, and clinical course of atelectasis after endoscopic resection. METHODS:A total of 349...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-3844-0
更新日期：2016-01-01 00:00:00
abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296684
更新日期：1987-01-01 00:00:00
abstract：:The effect of psyllium hydrophilic mucilloid (PHM) when used as a laxative and/or stool softener on serum cholesterol concentrations was examined in 176 ambulatory elderly participants attending a health screening program. The change in one-year serum cholesterol concentration in subjects using PHM was compared with t...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/BF01318205
更新日期：1991-03-01 00:00:00
abstract：:The major heat shock protein, HSP70, is known to be involved in cytoprotection against environmental stresses mediated by their function as a "molecular chaperone." However, the influence of HSP70 on gastric mucosal healing under physical stimulation or stress is not completely understood. Rat gastric mucosal cells (R...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-007-9795-3
更新日期：2007-11-01 00:00:00
abstract：:A novel peptide, submandibular gland peptide-T (SGP-T), which reduces allergen-induced hypotension, was examined for effects on intestinal anaphylaxis. Hooded-Lister rats were sensitized to egg albumin and prepared for the measurement of in vivo myoelectric activity of the jejunum. The disruption of migrating myoelect...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018847608184
更新日期：1997-11-01 00:00:00
abstract：:Modern methods of diagnosing diarrhea-predominant irritable bowel syndrome (D-IBS) require a "diagnosis of exclusion" approach. In this study we aim to test the diagnostic ability of using the fluctuation of frequency and consistency of bowel patterns in IBS to discriminate it from other causes of diarrhea. Eligible s...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-008-0694-z
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:MELD attempts to objectively predict the risk of mortality of patients with liver cirrhosis and is commonly used to prioritize organ allocation. Despite the usefulness of the MELD, updated metrics could further improve the accuracy of estimates of survival. AIMS:To assess and compare the prognostic ability ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5360-5
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Eosinophilic gastroenteritis (EOGE) is a rare idiopathic disease characterized by eosinophil-predominant inflammation of the stomach and/or intestines. Our aims are to determine the epidemiology, clinical features and outcomes of EOGE cases in a tertiary-care hospital. METHODS:Retrospective cohort study of ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4203-5
更新日期：2016-09-01 00:00:00
abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01311944
更新日期：1979-12-01 00:00:00
abstract：BACKGROUND:Primary malignant neoplasms of the small bowel comprise only 1-3% of all gastrointestinal malignancies. Small bowel cancers pose a significant diagnostic challenge. The recent development of video capsule endoscopy (VCE) and device-assisted enteroscopy (DAE) have greatly facilitated evaluation of the small b...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1640-z
更新日期：2011-09-01 00:00:00
abstract：:The aim of the study was to clarify whether nutrients are still capable of slowing gastric emptying following Roux-Y gastrectomy, as in normal dogs. Gastrointestinal motility and gastric emptying of acaloric and nutritive meals with different viscosities were measured in normal dogs and after a two-thirds Roux-Y gastr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296038
更新日期：1987-05-01 00:00:00
abstract：:Nonalcoholic steatohepatitis (NASH) is characterized by diffuse fatty infiltration in the liver and ballooning degeneration and inflammation in hepatocytes. We aimed to study the protective effect of soy isoflavones on experimental NASH and their effects on plasma paraoxanese and arylesterase levels in rats. Twenty-ei...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-9251-9
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Intestinal Behcet's disease (BD) is a specific subtype of BD. Effective drug therapy for intestinal BD remains elusive. AIMS:To investigate long-term outcomes and identify predictors of sustained response in intestinal BD patients receiving infliximab (IFX) treatment. METHODS:The medical records were revie...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4395-8
更新日期：2017-02-01 00:00:00
abstract：:Heme oxygenase (HO)-1, the rate-limiting enzyme in heme degradation, is induced by oxidative stress and its major end product, bilirubin, is a potent physiological antioxidant. We studied the induction of HO-1 and bilirubin production in intestinal mucosa using a rat model of sepsis. E. coli lipopolysaccharide was adm...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005626622203
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:The role of oxidative stress in inflammatory bowel diseases (IBD) has been extended lately from a simple consequence of inflammation to a potential etiological factor, but the data are still controversial. Active disease has been characterized before by an enhanced production of reactive oxygen species and t...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2510-z
更新日期：2013-05-01 00:00:00
abstract：:Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005697422454
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND AND AIM:Although the serum sodium level has been reported to be a prognostic and predictive marker for the therapeutic effects of lung cancer and renal cell carcinoma treated with molecular targeted therapy, the serum sodium level has not been investigated in hepatocellular carcinoma (HCC) patients treated w...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06380-6
更新日期：2020-06-17 00:00:00
abstract：:Oxygen radicals are important regulators in Helicobacter pylori-induced gastric ulceration and carcinogenesis. IL-8 may be regulated by oxidant-sensitive transcription factors, NF-kappaB, and AP-1. The present study aims to investigate whether H. pylori-induced IL-8 expression is regulated by NF-kappaB and AP-1 in gas...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1021963007225
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:Progressive hepatic fibrosis with development of cirrhosis is a feature of almost all chronic liver diseases. AIMS:We assessed the performance of Fibroscan in patients with chronic viral hepatitis, and in comparison with and combined with several surrogate serum markers for predicting cirrhosis. METHODS:In...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-010-1219-0
更新日期：2010-12-01 00:00:00
abstract：:Bone loss is an established complication of cholestatic liver cirrhosis, while little is known about bone mass and metabolism in noncholestatic liver cirrhosis. The aim of the present study is, therefore, to evaluate bone mass and mineral metabolism in patients with liver cirrhosis secondary to viral hepatitis. Bone m...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005568406664
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:Immune balances are important for many diseases including ulcerative colitis (UC). This study aimed to explore the role of the balance between CD8+ CD28+ and CD8+ CD28- T lymphocytes for the immunological pathogenesis of UC. METHODS:Sixteen patients with UC, 16 patients with irritable bowel syndrome (IBS) a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2327-9
更新日期：2013-01-01 00:00:00
abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01538066
更新日期：1989-09-01 00:00:00
abstract：:A 36-year-old female with a six-year history of Crohn's disease of the anus and colon was found to have in situ cloacogenic carcinoma of the anus after having undergone total proctocolectomy for massive bleeding. This case further supports the association between Crohn's disease of the gastrointestinal tract and its p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01395512
更新日期：1980-06-01 00:00:00
abstract：:The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 microgram/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308330
更新日期：1980-09-01 00:00:00
abstract：:The purpose of the present study was to investigate the Helicobacter pylori eradication potency of combined amoxicillin-omeprazole treatment in patients with duodenal ulcer disease and to compare the efficacy of two omeprazole and amoxicillin doses concerning H. pylori eradication, ulcer healing, pain relief, and safe...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02088052
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:Marijuana may be used by some patients with gastroparesis (Gp) for its potential antiemetic, orexigenic, and pain-relieving effects. AIMS:The aim of this study was to describe the use of marijuana by patients for symptoms of Gp, assessing prevalence of use, patient characteristics, and patients' perceived b...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05963-2
更新日期：2020-08-01 00:00:00
