Endoscopic therapy of the "sump" syndrome.

abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...

journal_title：Digestive diseases and sciences

authors： Heresbach D,Bretagne JF,Raoul JL,Moisan A,Siproudhis L,Devillers A,Gosselin M

更新日期：1993-09-01 00:00:00

abstract：PURPOSE:In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or...

journal_title：Digestive diseases and sciences

authors： Szamosi T,Lakatos PL,Hungarian IBD Study Group.,Szilvasi A,Lakatos L,Kovacs A,Molnar T,Altorjay I,Papp M,Szabo O,Satori A,Tulassay Z,Miheller P,Horvath HC,Papp J,Tordai A,Andrikovics H

更新日期：2009-02-01 00:00:00

abstract：:A 36-year-old female with a six-year history of Crohn's disease of the anus and colon was found to have in situ cloacogenic carcinoma of the anus after having undergone total proctocolectomy for massive bleeding. This case further supports the association between Crohn's disease of the gastrointestinal tract and its p...

journal_title：Digestive diseases and sciences

authors： Daly JJ,Madrazo A

更新日期：1980-06-01 00:00:00

abstract：:Sonic Hedgehog (Shh) signaling has been extensively studied for its role in developmental biology and cancer biology. The association between Shh and cancer development in general is well established but the functional role of Shh in the development and progression of gastric cancer specifically is largely unknown. Bo...

journal_title：Digestive diseases and sciences

authors： Martin J,Donnelly JM,Houghton J,Zavros Y

更新日期：2010-06-01 00:00:00

abstract：:Campylobacter pyloridis has been associated with antral gastritis and duodenal ulcer. To study the pathogenetic role of these organisms in duodenal ulcer, endoscopic biopsies, two from the first part of duodenum, four from antrum, and four from body and fundus, were taken before and after four weeks of cimetidine trea...

journal_title：Digestive diseases and sciences

authors： Hui WM,Lam SK,Chau PY,Ho J,Lui I,Lai CL,Lok AS,Ng MM

更新日期：1987-11-01 00:00:00

abstract：:This study determined the effect of low-frequency and high-frequency gastric electrical stimulation (GES) on canine lower esophageal sphincter (LES) pressure and also evaluated the effect of such stimulation on neurohumoral factors that modulate LES pressure. Eight dogs were fitted with stimulation wires along the gre...

journal_title：Digestive diseases and sciences

authors： Xing J,Felsher J,Brody F,Soffer E

更新日期：2005-08-01 00:00:00

abstract：:Pregnancy is a time when women are susceptible to bowel habit perturbations. The purpose of this study was to provide new baseline data for a range of bowel habit parameters. Prospective 7-day bowel habit diaries were completed during each of the three trimesters of pregnancy and after birth. Sensations of incomplete ...

journal_title：Digestive diseases and sciences

authors： Derbyshire EJ,Davies J,Detmar P

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Approximately 10% of children with celiac disease (CD) have ultra-short celiac disease (USCD), where histological abnormalities are limited to the duodenal bulb. The aim of our retrospective study was to identify clinical and serological characteristics at baseline and at follow-up of children with ...

journal_title：Digestive diseases and sciences

authors： Doyev R,Cohen S,Ben-Tov A,Weintraub Y,Amir A,Galai T,Moran-Lev H,Yerushalmy-Feler A

更新日期：2019-01-01 00:00:00

abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

journal_title：Digestive diseases and sciences

authors： Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

更新日期：1979-12-01 00:00:00

abstract：:We report a rare case of secondary involvement of the gallbladder by metastatic renal cell carcinoma. A 71-year-old man was diagnosed as having a polypoid mass within the gallbladder when he underwent right nephrectomy for a renal cell carcinoma. A preoperative diagnosis of simultaneous carcinoma of the gallbladder wa...

journal_title：Digestive diseases and sciences

authors： Satoh H,Iyama A,Hidaka K,Nakashiro H,Harada S,Hisatsugu T

更新日期：1991-04-01 00:00:00

abstract：:This study evaluates the hypothesis that cerulein relaxes the sphincter of Oddi (SO) via nitric oxide (NO). The spontaneous motility and the response to cerulein on the canine SO were recorded using a constant-perfusion technique. N(G)-L-arginine-methyl-ester (L-NAME) increased the spontaneous motility and dose-depend...

journal_title：Digestive diseases and sciences

authors： Shima Y,Mori M,Harano M,Tsuge H,Tanaka N,Yamazato T

更新日期：1998-03-01 00:00:00

abstract：:The effect of ischemia-reperfusion and 48-hr fasting on apoptosis was characterized in rat gastric mucosa and compared to small intestinal mucosa. Under halothane anesthesia, the celiac artery or superior mesenteric artery in the rat was occluded for 60 min followed by reperfusion. Occlusion of the celiac artery reduc...

journal_title：Digestive diseases and sciences

authors： Fukuyama K,Iwakiri R,Noda T,Kojima M,Utsumi H,Tsunada S,Sakata H,Ootani A,Fujimoto K

更新日期：2001-03-01 00:00:00

abstract：:We studied the effects of an ileocolonic sphincter substitute on canine small intestine motor activity. Recordings of fasting and postprandial myoelectrical activity were performed in three groups of animals in whom the following procedures had been performed: (1) electrode placement alone, intestinal continuity undis...

journal_title：Digestive diseases and sciences

authors： Quigley EM,Thompson JS,Lof J

更新日期：1989-09-01 00:00:00

abstract：:Infection with Helicobacter increases the transcellular passage of macromolecules across the epithelium, and this effect can be prevented by a gastroprotective agent rebamipide. The aim was to gain insight into the mechanisms involved. The HT29-19A intestinal epithelial cells grown on microporous filters as monolayers...

journal_title：Digestive diseases and sciences

authors： Matysiak-Budnik T,Thomas-Collignon A,Mégraud F,Heyman M

更新日期：2001-07-01 00:00:00

abstract：:The synthetic prostanoid, Ro 22-6923, was studied for its effects on canine gastric secretion. Histamine-stimulated acid secretion was inhibited for up to 8 hr after an orally administered dose of 0.25 mg/kg Ro 22-6923. In the Amdrup (modified Pavlov) pouch model, Ro 22-6923 significantly inhibited food-stimulated aci...

journal_title：Digestive diseases and sciences

authors： Gaginella TS,Bertko RJ,Müller RK,Gallo-Torres H,Sullivan AC

更新日期：1985-04-01 00:00:00

abstract：:Endoscopic injection sclerotherapy is known to cause a variety of motility abnormalities, but the correlation between these changes and symptomatology has not been clearly defined. To assess the effects of endoscopic sclerosis of varices on esophageal function and symptoms, we prospectively studied esophageal motility...

journal_title：Digestive diseases and sciences

authors： Cohen LB,Simon C,Korsten MA,Scherl EJ,Skorniky J,Guelrud MB,Waye JD

更新日期：1985-01-01 00:00:00

abstract：:Anorexia nervosa is considered one type of eating disorder that may result in severe malnutrition. Patients with this disorder commonly complain of postprandial nausea, abdominal pain, and distension. We describe the radiologic and motility abnormalities associated with anorexia nervosa in a 21-year-old female. Barium...

journal_title：Digestive diseases and sciences

authors： Buchman AL,Ament ME,Weiner M,Kodner A,Mayer EA

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown. AIMS:Th...

journal_title：Digestive diseases and sciences

authors： Im JP,Ye BD,Kim JM,Jung HC,Song IS,Kim JS

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:To date, there are no studies reporting an association between vitamin D and Barrett's esophagus (BE), the precursor for esophageal adenocarcinoma (EAC). AIMS:Our aim was to study the association between serum 25-hydroxyvitamin D (25(OH)D) levels and prevalence and incidence of dysplasia/EAC in BE. METHODS...

journal_title：Digestive diseases and sciences

authors： Thota PN,Kistangari G,Singh P,Cummings L,Hajifathalian K,Lopez R,Sanaka MR

更新日期：2016-01-01 00:00:00

abstract：:The distribution of tissue kallikrein (TK) and its plasma inhibitor, kallistatin in plasma and intestinal tissue, was studied in patients with active ulcerative colitis (UC) and Crohn's disease (CD). TK was localized to goblet cells and kallistatin to epithelial cells of normal human intestine. Both proteins are visua...

journal_title：Digestive diseases and sciences

authors： Stadnicki A,Mazurek U,Gonciarz M,Plewka D,Nowaczyk G,Orchel J,Pastucha E,Plewka A,Wilczok T,Colman RW

更新日期：2003-03-01 00:00:00

abstract：:Previous studies have shown that duodenal motility patterns differ in preterm and term infants, but antral motor activities were not compared. Using a validated, low-compliance, continuous-perfusion, neonatal manometric system, antral and duodenal motility was studied in 19 preterm and nine term infants. Antral motili...

journal_title：Digestive diseases and sciences

authors： Ittmann PI,Amarnath R,Berseth CL

更新日期：1992-01-01 00:00:00

abstract：:A sustained increase in cytosolic Ca2+ can damage gastric mucosal cells. The present study has examined the role of Ca2+ in thromboxane B2 (TXB2)-mediated damage of rabbit isolated gastric mucosal cells. Cells were isolated from rabbit oxyntic mucosa by collagenase-EDTA digestion. Cell metabolic activity and cell dama...

journal_title：Digestive diseases and sciences

authors： Wong HM,Soper BD,Tepperman BL

更新日期：1995-09-01 00:00:00

abstract：:The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported. This increased failure rate of livers obtained from adult females and t...

journal_title：Digestive diseases and sciences

authors： Pillay P,Van Thiel DH,Gavaler JS,Starzl TE

更新日期：1990-06-01 00:00:00

abstract：:We describe the first reported case of mantle zone lymphoma of the colon presenting as diffuse ileocolitis simulating severe inflammatory bowel disease. This case serves to illustrate the importance of immunohistochemistry in establishing the diagnosis of lymphoma in extranodal sites. ...

journal_title：Digestive diseases and sciences

authors： McCullough JE,Kim CH,Banks PM

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is a chronic condition and the most common form of inflammatory bowel disease. The goal of standard treatment is mainly to induce and maintain remission with anti-inflammatory, immunosuppressive agents, and/or colectomy. Fecal microbiota transplantation (FMT) has been used successfull...

journal_title：Digestive diseases and sciences

authors： Tian Z,Liu J,Liao M,Li W,Zou J,Han X,Kuang M,Shen W,Li H

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:A significant proportion of patients with Crohn's disease (CD) lose response to antibodies directed against tumor necrosis factor α (TNF). Prior TNF-antagonist failure is associated with lower rates of response to subsequent TNF-antagonist therapy. In patients failing two anti-TNF agents, a choice exists b...

journal_title：Digestive diseases and sciences

authors： Ananthakrishnan AN,Hur C,Korzenik JR

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:Assessment of whole gut transit, by radio-opaque markers or scintigraphy, is used to evaluate patients with constipation for slow gastrointestinal transit. Wireless capsule motility, using the SmartPill GI monitoring system, samples and transmits intraluminal pH, pressure, and temperature data from a capsu...

journal_title：Digestive diseases and sciences

authors： Maqbool S,Parkman HP,Friedenberg FK

更新日期：2009-10-01 00:00:00

abstract：:A muscarinic receptor subtype 1 (M1) antagonist, pirenzepine, recently has been shown to be relatively free of the usual anticholinergic side effects on esophageal smooth muscle and thus has been implicated for the treatment of gastroesophageal reflux disease (GERD). However, the effect of pirenzepine on GERD remains ...

journal_title：Digestive diseases and sciences

authors： Sato TL,Wu WC,Castell DO

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Biosimilar approval, such as Inflectra™ (CT-P13) for treating ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though clinicians are comfortable with biosimilar use in treatment-naïve patients, there are concerns in some jurisdictions that there are insufficient data ...

journal_title：Digestive diseases and sciences

authors： Bernard EJ,Fedorak RN,Jairath V

更新日期：2020-08-01 00:00:00

abstract：:Azithromycin (Zithromax), an erythromycin derivative that belongs to a subgroup of the macrolides known as azolides, has generally been considered to be a very safe medication. Hepatic side effects are uncommon but may include jaundice, fever, and right upper quadrant pain. Herein we describe a patient who developed a...

journal_title：Digestive diseases and sciences

authors： Chandrupatla S,Demetris AJ,Rabinovitz M

更新日期：2002-10-01 00:00:00