Abstract：
:Nine patients with concurrent myelodysplastic syndrome (MDS) and inflammatory bowel disease (IBD) were examined. Median age at diagnosis of these patients was similar to the usual age of patients at diagnosis of IBD only. There was a strong predominance of Crohn's disease (seven of nine cases), with an unusually high frequency of colorectal involvement (five of nine cases). Inflammatory bowel disease was diagnosed first in one patient, MDS first in five patients, and both diseases were diagnosed simultaneously in three patients. All patients had moderate or severe anemia. The prognosis of IBD was determined by MDS. These observations suggest that there is an unclear common pathogenesis of IBD and MDS and, consequently that patients with IBD and anemia of non-obvious origin should be evaluated for the presence of MDS.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Wang Z,Zhou Y,Liu Ydoi
10.1007/s10620-007-0090-0subject
Has Abstractpub_date
2008-07-01 00:00:00pages
1929-32issue
7eissn
0163-2116issn
1573-2568journal_volume
53pub_type
杂志文章,评审abstract：BACKGROUND:Endoscopic ablation of duodenal ampullary malignancy has not been fully assessed. AIMS:The study aimed to evaluate the efficacy and safety of Endoscopic retrograde cholangiopancreatograpy (ERCP)-guided radiofrequency ablation (RFA) for inoperable ampullary cancer. METHODS:Patients with inoperable ampullary...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05849-3
更新日期：2020-05-01 00:00:00
abstract：:These studies were done to determine the effects of fluoride (F) on the structure and function of the canine gastric mucosa and the possible protective effects of 16,16-dimethyl-prostaglandin E2 (dmPGE2). A portion of the stomach with its vascular supply intact was mounted in a two-compartment chamber, one side of whi...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018895207333
更新日期：1997-10-01 00:00:00
abstract：:The characteristic features of a 48-year-old male presenting with isolated acromegaly caused by a GRH-producing pancreatic endocrine tumor bearing no relation to MEN1 was reported. The clinical features, laboratory findings, and sellar enlargement were improved after removal of the pancreatic tumor. The resected pancr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018818811199
更新日期：1997-07-01 00:00:00
abstract：:Growth factors, such as epidermal growth factor (EGF), are known to protect upper gut mucosa against irritants and to enhance healing of ulcerative lesions in animal models. A number of salivary growth factors are found in human saliva. The aim of this study was to determine if salivary growth factors and cytokines ar...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005615703009
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND:Different factors have been associated with prolonged fluoroscopy time (FT) during endoscopic retrograde cholangiopancreatography (ERCP). AIM:We hypothesize that FT depends on both the anatomical location of the pathology managed during ERCP and the complexity of the ERCP. METHODS:Three centers participate...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究
doi：10.1007/s10620-014-3508-5
更新日期：2015-06-01 00:00:00
abstract：:We examined the role of capsaicin-sensitive afferent neurons in pH-dependent gastrin secretion in the rat stomach. The change in serum gastrin levels relative to changes in luminal pH (using omeprazole for luminal alkalization or 0.1 N HCl for luminal acidification) was studied after oral administration of 4% lidocain...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005570507166
更新日期：2000-06-01 00:00:00
abstract：:Patients with gallstone disease have impaired gallbladder motility. Prostaglandins are thought to be important mediators of gallbladder hypomotility. We assessed the effect of aspirin, a prostaglandin inhibitor on gallbladder resting volume and ejection fraction according to a double-blind study protocol in 20 healthy...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02212702
更新日期：1995-08-01 00:00:00
abstract：:Glycoprotein and glycolipid constituents were examined in purified microvillus and basolateral membranes isolated from rat small intestinal epithelial cells. SDS-polyacrylamide gel electrophoresis showed that the molecular weights of most of the major proteins from microvillus membranes were over 100 kD, whereas the m...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536338
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND AND AIM:The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4120-7
更新日期：2016-08-01 00:00:00
abstract：:Our aim was to compare standard liver function tests (serum bilirubin, serum albumin and prothrombin concentration), with lidocaine and monoethylglycinexylidide pharmacokinetic parameters, after oral lidocaine administration, to assess hepatic function of cirrhotic individuals. Twenty-one consecutive cirrhotic patient...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1023/a:1026630313038
更新日期：1999-04-01 00:00:00
abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5029-0
更新日期：2018-06-01 00:00:00
abstract：:In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296773
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4127-0
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Approximately 10-28 % of patients experience adverse drug reactions related to treatment with thiopurines. The most serious reaction is myelosuppression, typically manifested as leucopenia, which occurs in approximately 2-5 % of patients. Other adverse drug reactions that often accompany thiopurine therapy a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2163-y
更新日期：2012-09-01 00:00:00
abstract：:A primary histiocytic lymphoma arising in the esophagus and its resultant spontaneous perforation is reported in a 69-year-old female. To our knowledge esophageal perforation occurring as a complication of a primary non-Hodgkin's lymphoma of the esophagus has not been previously reported. ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01324957
更新日期：1983-04-01 00:00:00
abstract：:The effects of 10-day bilateral adrenalectomy on morphometry, proliferation, and apoptosis were determined in the small intestine of 3-month-old Sprague-Dawley rats. The activities of sucrase, lactase, and its respective mRNA, aminopeptidase N, and intestinal alkaline phosphatase were also evaluated. Adrenalectomy lea...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1010611228730
更新日期：2001-06-01 00:00:00
abstract：:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary pe...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01297143
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND AND AIMS:Although ampullary cancer is a relatively uncommon malignancy, it is frequently associated with biliary obstruction. Endoscopic biliary drainage is regarded as a palliative treatment of choice for patients with inoperable ampullary cancer. However, there are no data concerning choice of stent in thi...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-011-1909-2
更新日期：2012-03-01 00:00:00
abstract：:Significant species differences have been demonstrated in gastric physiology, a factor that limits extrapolation of animal data to man. Primate physiology is thought to be similar to that of man; however, gastric function has not been adequately documented in the primate. In the present study six baboons (body weight ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01295997
更新日期：1992-09-01 00:00:00
abstract：UNLABELLED:Recent evidence suggests that psychological factors may affect esophageal as well as intestinal motility. To study this further, we compared the psychological profiles of 20 irritable bowel patients and 20 patients with recurrent noncardiac chest pain associated with high-amplitude peristaltic contractions i...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01300697
更新日期：1986-02-01 00:00:00
abstract：:An association between hypothermia and gastric ulceration has been reported in rats in cervical cord section and in restraint models. The present study was designed to determine this relationship in cervical and in lumbar cord sectioned Sprague-Dawley rats. Ambient temperatures were varied by placing the sectioned ani...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01307976
更新日期：1981-01-01 00:00:00
abstract：BACKGROUND:Intestinal Behcet's disease (BD) is a specific subtype of BD. Effective drug therapy for intestinal BD remains elusive. AIMS:To investigate long-term outcomes and identify predictors of sustained response in intestinal BD patients receiving infliximab (IFX) treatment. METHODS:The medical records were revie...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4395-8
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:A new prepared oral viscous budesonide (PVB) has been effective in inducing clinical and histological remission in pediatric eosinophilic esophagitis (EoE). AIMS:To evaluate the efficacy of a 12-week maintenance therapy on clinical, endoscopic, and histological remission using half of the dose used in the i...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-018-5449-x
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree of inflammation, while chemoprevention ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-009-0942-x
更新日期：2010-06-01 00:00:00
abstract：:Hepatocellular carcinoma (HCC) is a highly morbid and prevalent cancer globally. While high quality evidence for mortality benefit of HCC surveillance is lacking, early detection of HCC is likely beneficial as prognosis is highly correlated with tumor stage. High risk populations, including patients with cirrhosis and...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-020-06550-6
更新日期：2020-12-01 00:00:00
abstract：:Up to 60% of patients with IBS have lowered perception thresholds in the rectum to balloon distension. The current study sought to test the hypothesis that IBS patients with normal perception thresholds in the rectum show hypersensitivity of afferent pathways in the sigmoid colon. Eleven healthy normal subjects and ei...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018817132213
更新日期：1997-06-01 00:00:00
abstract：BACKGROUND AND AIMS:Accumulating evidence has indicated that variations of mitochondrial DNA (mtDNA) content may affect the susceptibility to hepatocellular carcinoma (HCC). However, no study has been conducted to evaluate the association of circulating mtDNA content and the risk of liver cirrhosis, a leading cause of ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-3523-1
更新日期：2015-06-01 00:00:00
abstract：:Motion sickness provides a unique setting for the study of nausea. Studies of illusory self-motion have linked nausea and objective measures of gastric dysrhythmias and the stress hormones vasopressin and epinephrine. Electrogastrographic methods utilize Ag-AgCl electrodes placed on the abdominal surface in the epigas...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Approximately 10% of children with celiac disease (CD) have ultra-short celiac disease (USCD), where histological abnormalities are limited to the duodenal bulb. The aim of our retrospective study was to identify clinical and serological characteristics at baseline and at follow-up of children with ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5323-x
更新日期：2019-01-01 00:00:00
abstract：:Ischemic enterocolitis is a well-recognized entity occurring in cocaine users. Diagnosis is based on the presence of rectal bleeding, abdominal pain, a history of cocaine use, supportive endoscopic and histopathologic findings, and the absence of other etiologic mechanisms of ischemic colitis. In this study, we evalua...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018839415743
更新日期：1997-07-01 00:00:00
