Acid-sensitive and alkaline-sensitive sensory neurons regulate pH dependent gastrin secretion in rat.

abstract：:Intraoperative radiation therapy has been introduced to improve survival rates after resection of biliopancreatic cancer. Early and late effects of intraoperative radiation on the exocrine and endocrine functions of the residual pancreas were examined in 54 patients with pancreatic head resection. Of the 54 patients, ...

journal_title：Digestive diseases and sciences

authors： Yamaguchi K,Nakamura K,Kimura M,Yokohata K,Noshiro H,Chijiiwa K,Tanaka M

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Adenosine deaminase acting on RNA 1 (ADAR1) is known to mediate deamination of adenosine-to-inosine through binding to double-stranded RNA, the phenomenon known as RNA editing. Currently, the function of ADAR1 in gastric cancer is unclear. AIMS:This study was aimed at investigating RNA editing-dependent and...

journal_title：Digestive diseases and sciences

authors： Cho CJ,Jung J,Jiang L,Lee EJ,Kim DS,Kim BS,Kim HS,Jung HY,Song HJ,Hwang SW,Park Y,Jung MK,Pack CG,Myung SJ,Chang S

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Tyrosine phosphorylation and dephosphorylation by protein tyrosine kinases and phosphatases (PTPs), respectively, play crucial roles in cellular signal transduction. Protein phosphatase non-receptor type 11 (PTPN11) is a positive signaling PTP that activates RAS and ERK signaling. Also, the PTPN11 binds with...

journal_title：Digestive diseases and sciences

authors： Kim JS,Shin OR,Kim HK,Cho YS,An CH,Lim KW,Kim SS

更新日期：2010-06-01 00:00:00

abstract：:We prospectively assessed the relationship between nodular gastritis and Helicobacter pylori infection. Of 1409 adults who underwent endoscopy for persistent dyspepsia between June 2004 and August 2005, 41 (2.9%) patients were diagnosed with nodular gastritis (11 [27%] men and 30 [73%] women). The mean age was 45.9 ye...

journal_title：Digestive diseases and sciences

authors： Chen MJ,Wang TE,Chang WH,Liao TC,Lin CC,Shih SC

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Concerns over the hypothetical adverse effects of water absorption and the disturbance of serum sodium and potassium levels prompted a quality assurance evaluation of water exchange (WE) colonoscopy. AIM:The purpose of this study was to evaluate the balance of water infused and suctioned in WE colonoscopy, ...

journal_title：Digestive diseases and sciences

authors： Leung JW,Siao-Salera R,Abramyan O,Mann SK,Ward G,Yen A,Gutierrez R,Leung FW

更新日期：2014-03-01 00:00:00

abstract：:A patient with congenital asucrasia was investigated using in vivo differential urinary disaccharide excretion. Impaired hydrolysis of sucrose and isomaltose, but normal lactase activity, were demonstrated and confirmed by in vitro estimation. The technique of differential disaccharide excretion can now be used to ass...

journal_title：Digestive diseases and sciences

authors： Maxton DG,Catt SD,Menzies IS

更新日期：1989-01-01 00:00:00

abstract：:The aim of this study was to compare the effect on HCV RNA levels of using induction dosing with 5 MU interferon-alpha2b (IFN) given daily for four weeks followed by 5 MU IFN given three times a week (TIW) for 44 weeks vs standard noninduction TIW dosing of 5 MU IFN for 48 weeks. We randomly assigned 135 patients with...

journal_title：Digestive diseases and sciences

authors： Gonzalez HJ,Ho SB,Gross JB,Peine C,McKee D,Smith T,Midwest Hepatitis Study Group.

更新日期：2002-04-01 00:00:00

abstract：:Concordance between gram-negative enteric and other toxin-producing bacteria in blood and stool culture, endotoxin (lipopolysaccharide), and interleukin-6 (IL-6) was measured in 60 preterm infants (600-1600 g) as a clinical index in neonatal necrotizing enterocolitis (NEC). E. coli, Klebsiella, Enterobacter, and Clost...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Carrion V,Griffiths E,Dryja D,Hilty M,Rook C,Morin F 3rd

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Obesity, gastroesophageal reflux, and Barrett's esophagus have all been linked to esophageal adenocarcinoma. In addition, the decline in Helicobacter pylori (H. pylori) infection in affluent societies has also been suggested to be a major factor in the recent rise in the incidence of esophageal adenocarcinom...

journal_title：Digestive diseases and sciences

authors： Lee YY,Raj SM,Sharif SE,Salleh R,Ayub MC,Graham DY

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Little is known on practice patterns of endoscopists for the management of Barrett's esophagus (BE) over the last decade. AIMS:Our aim was to assess practice patterns of endoscopists for the diagnosis, surveillance and treatment of BE. METHODS:All members of the Italian Society of Digestive Endoscopy (SIED...

journal_title：Digestive diseases and sciences

authors： Zagari RM,Eusebi LH,Galloro G,Rabitti S,Neri M,Pasquale L,Bazzoli F

更新日期：2020-09-28 00:00:00

abstract：BACKGROUND:Liver metastasis is an indicator of unfavorable responses to immunotherapy in colorectal cancer patients. However, the difference of immune microenvironment between primary tumors and liver metastases has not been well understood. PATIENTS AND METHODS:Fifty-four colon cancer with liver metastasis patients w...

journal_title：Digestive diseases and sciences

authors： Zhou SN,Pan WT,Pan MX,Luo QY,Zhang L,Lin JZ,Zhao YJ,Yan XL,Yuan LP,Zhang YX,Yang DJ,Qiu MZ

更新日期：2020-03-19 00:00:00

abstract：:Two hundred forty-six patients with a wide range of upper gastrointestinal tract disorders were investigated for the presence of Campylobacter pylori infection in esophagus, gastric antrum, and duodenum. C. pylori was identified in 52% of patients in at least one site, and microbiological and histological techniques w...

journal_title：Digestive diseases and sciences

authors： Coelho LG,Das SS,Payne A,Karim QN,Baron JH,Walker MM

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Hepatoportal sclerosis (HPS) is a clinicopathologic condition that is clinically characterized by portal hypertension (varices and portosystemic collateral vessels), splenomegaly and pancytopenia, in the absence of cirrhosis. Although the etiology is obscure, a number of theories such as immunologic...

journal_title：Digestive diseases and sciences

authors： Beyazit Y,Ibis M,Purnak T,Turhan T,Kekilli M,Kurt M,Sayilir A,Onal IK,Turhan N,Tas A,Köklü S,Haznedaroglu IC

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD...

journal_title：Digestive diseases and sciences

authors： Zhang RN,Zheng RD,Mi YQ,Zhou D,Shen F,Chen GY,Zhu CY,Pan Q,Fan JG

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Biosimilar approval, such as Inflectra™ (CT-P13) for treating ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though clinicians are comfortable with biosimilar use in treatment-naïve patients, there are concerns in some jurisdictions that there are insufficient data ...

journal_title：Digestive diseases and sciences

authors： Bernard EJ,Fedorak RN,Jairath V

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree of inflammation, while chemoprevention ...

journal_title：Digestive diseases and sciences

authors： Tang J,Sharif O,Pai C,Silverman AL

更新日期：2010-06-01 00:00:00

abstract：:Excessive spontaneous swallowing has been associated with a variety of common gastrointestinal symptoms including abdominal pain, heartburn, and bloating and may contribute to disorders such as hiatus hernia, duodenal ulcer, and irritable bowel syndrome. The present study investigated the hypothesis that changes in em...

journal_title：Digestive diseases and sciences

authors： Cuevas JL,Cook EW 3rd,Richter JE,McCutcheon M,Taub E

更新日期：1995-02-01 00:00:00

abstract：:In 1958 the Yale freshman class gave blood samples as part of a study intended to determine the predictive value of plasma pepsinogen (PP) for the subsequent development of duodenal ulcer (DU). We report a long-term follow-up of this cohort. A self-administered questionnaire designed to ascertain information about the...

journal_title：Digestive diseases and sciences

authors： Chuong JJ,Fisher RL,Chuong RL,Spiro HM

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00

abstract：:Symptom scores, stool data, and the transit of a standard, solid meal were measured in 28 patients with irritable bowel syndrome (IBS) during baseline conditions and after five weeks of treatment with placebo and loperamide, given as a flexible dosage regime in the form of a double-blind, cross-over trial. All patient...

journal_title：Digestive diseases and sciences

authors： Cann PA,Read NW,Holdsworth CD,Barends D

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:The endoscopic detection of esophageal cancer is suboptimal in both patients referred with dyspeptic symptoms and those enrolled in Barrett's surveillance programs. MCM5 expression in cells collected from gastric fluid may be correlated with the presence of dysplasia or adenocarcinoma. Analysis of this bioma...

journal_title：Digestive diseases and sciences

authors： Everson M,Magee C,Alzoubaidi D,Brogden S,Graham D,Lovat LB,Novelli M,Haidry R

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Antibiotic prophylaxis can reduce the incidence of the first episode and recurrent episodes of spontaneous bacterial peritonitis (SBP) in high-risk cirrhotic patients. However, recent data suggest that SBP prophylaxis may be underused. It is unclear how many cases of cirrhosis that develop SBP might actually...

journal_title：Digestive diseases and sciences

authors： Ngamruengphong S,Nugent K,Rakvit A,Parupudi S

更新日期：2011-09-01 00:00:00

abstract：AIM:The aim of this case-control study was to investigate both the distribution of MCP-1, eNOS, tPA and PAI-1 gene polymorphism and correlation of genotypes and phenotypes. METHOD:Between September 1997-January 2005, 20 patients with HPS (group 1) were compared with a group of cirrhotic patients (group 2, n = 19) as w...

journal_title：Digestive diseases and sciences

authors： Tumgor G,Berdeli A,Arikan C,Levent E,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Fibrin ring granuloma is characterized by a fibrinous ring surrounding a central fat vacuole. It has been found in the liver and bone marrow of patients with Q fever, and occasionally with visceral leishmaniasis, cytomegalovirus, Epstein-Barr virus, Staphylococcus epidermidis infections, Hodgkin's lymphoma, and hypers...

journal_title：Digestive diseases and sciences

authors： Ruel M,Sevestre H,Henry-Biabaud E,Courouce AM,Capron JP,Erlinger S

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Improved survival with chronic liver disease (CLD) and increased incidence in the older has led to a rapidly expanding population which faces similar "geriatric syndromes" as the general population. With risk factors such as autonomic dysfunction, cognitive impairment, and muscle abnormalities in CLD it is e...

journal_title：Digestive diseases and sciences

authors： Frith J,Kerr S,Robinson L,Elliott CS,Wilton K,Jones DE,Day CP,Newton JL

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

journal_title：Digestive diseases and sciences

authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

更新日期：2008-08-01 00:00:00

abstract：:The preoperative determination of the localization of a small insulinoma is sometimes difficult using routine imaging techniques. We have used the selective arterial calcium injection (SACI) test to determine the location of the tumor preoperatively. The pathophysiologic basis of the SACI test is based on the responsi...

journal_title：Digestive diseases and sciences

authors： Kato M,Doi R,Imamura M,Okada N,Shimada Y,Hosotani R,Miyazaki JI

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Fibromyalgia (FM) is a disorder characterized by widespread chronic pain as core symptom and a broad range of comorbidities. Despite the prevalence of gastrointestinal (GI) comorbidities in patients with FM, GI functions have rarely been investigated in animal models of FM. AIMS:The purpose of the present s...

journal_title：Digestive diseases and sciences

authors： Uchida M,Kobayashi O,Yoshida M,Miwa M,Miura R,Saito H,Nagakura Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) is a safe and effective way to sample lesions in the gastrointestinal tract. Rapid on-site specimen evaluation (ROSE) improves the accuracy of EUS-FNA. While data suggests that EUS with fine-needle biopsy (EUS-FNB) is effective, it remains unclear...

journal_title：Digestive diseases and sciences

authors： Krishnan K,Dalal S,Nayar R,Keswani RN,Keefer L,Komanduri S

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00