Overexpression of protein phosphatase non-receptor type 11 (PTPN11) in gastric carcinomas.

abstract：:We reviewed the discharge records of all diabetic ketoacidosis hospitalizations over 30 months for the presence of clinically significant upper gastrointestinal hemorrhage. Of 284 hospitalizations in 193 patients, hemorrhage occurred in 26 hospitalizations (9%) in 25 patients (13%). None required invasive therapy to a...

journal_title：Digestive diseases and sciences

authors： Faigel DO,Metz DC

更新日期：1996-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection has an estimated prevalence of 3% around the world. Unfortunately, many persons with HCV infection are asymptomatic. The aim of this study was to determine the prevalence of hepatitis C Virus infection in asymptomatic persons. This study was carried out in a population-based cross-sec...

journal_title：Digestive diseases and sciences

authors： Méndez-Sánchez N,Ponciano-Rodriguez G,Chávez-Tapia NC,Motola-Kuba D,Almeda-Valdes P,Sánchez-Lara K,Ramos MH,Uribe M

更新日期：2005-04-01 00:00:00

abstract：:This study assessed the mucosal antioxidant response during acute (mouse) and chronic (adult human) H. pylori infection and following N-acetylcysteine administration. Antral biopsies were obtained from 44 patients (16 infected, 28 noninfected). Sixty-nine mice were sacrificed after 1 (n = 25), 4 (n = 28), or 6 (n = 16...

journal_title：Digestive diseases and sciences

authors： Matthews GM,Tivey D,Cummins AG,Butler RN

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The Gastroenterology Core Curriculum requires training in women's digestive disorders; however, requirements do not necessarily produce knowledge and competence. Our study goals were: (1) to compare perceptions of education, fellow-reported levels of competence, and attitudes towards training in wom...

journal_title：Digestive diseases and sciences

authors： Saha S,Roberson E,Richie K,Lindstrom MJ,Esposti SD,Wald A

更新日期：2011-03-01 00:00:00

abstract：:Angiotensin II (Ang II) has been reported to promote tumor progression, tumor growth and angiogenesis in many cancers. We previously observed that angiotensin II type 1 receptors (AT1R) were upregulated in human gastric cancer and may be involved in the progression of gastric cancer. We studied the effects of AT1R ant...

journal_title：Digestive diseases and sciences

authors： Huang W,Wu YL,Zhong J,Jiang FX,Tian XL,Yu LF

更新日期：2008-05-01 00:00:00

abstract：:In Japanese healthy CYP2C19 extensive metabolizers, rabeprazole 10 mg shows a faster onset of action and stronger inhibition of acid secretion than does omeprazole 20 mg on the first 3 days of administration. We evaluated gastric ulcer improvement after 1 week's treatment with rabeprazole or omeprazole in relation to ...

journal_title：Digestive diseases and sciences

authors： Ando T,Ishikawa T,Kokura S,Naito Y,Yoshida N,Yoshikawa T

更新日期：2008-04-01 00:00:00

abstract：:Twenty-eight patients with delayed gastric emptying as measured by an abnormal barium "burger" were treated with metoclopramide in a randomized, double-blind fashion. Five had diabetic gastroparesis, four had undergone vagotomy and pyloroplasty, and 19 were idiopathic. Patients received either metoclopramide or placeb...

journal_title：Digestive diseases and sciences

authors： Perkel MS,Moore C,Hersh T,Davidson ED

更新日期：1979-09-01 00:00:00

abstract：:Consistent regression of intestinal metaplasia in Barrett's esophagus has not been achieved with medical or surgical interventions. In this case report, a patient with Barrett's esophagus of stable length had half the circumference of the Barrett's epithelium ablated with laser therapy while on a high-dose proton-pump...

journal_title：Digestive diseases and sciences

authors： Sampliner RE,Hixson LJ,Fennerty MB,Garewal HS

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Biosimilar approval, such as Inflectra™ (CT-P13) for treating ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though clinicians are comfortable with biosimilar use in treatment-naïve patients, there are concerns in some jurisdictions that there are insufficient data ...

journal_title：Digestive diseases and sciences

authors： Bernard EJ,Fedorak RN,Jairath V

更新日期：2020-08-01 00:00:00

abstract：:We studied the effects of an ileocolonic sphincter substitute on canine small intestine motor activity. Recordings of fasting and postprandial myoelectrical activity were performed in three groups of animals in whom the following procedures had been performed: (1) electrode placement alone, intestinal continuity undis...

journal_title：Digestive diseases and sciences

authors： Quigley EM,Thompson JS,Lof J

更新日期：1989-09-01 00:00:00

abstract：AIM:To identify the clinical and biochemical predictors of histologic disease severity in patients with non-alcoholic steatohepatitis (NASH). METHOD:Clinical, anthropometric and biochemical data of 71 consecutive patients with a histological diagnosis of NASH were retrieved from the medical database. The histologic cr...

journal_title：Digestive diseases and sciences

authors： Singh DK,Sakhuja P,Malhotra V,Gondal R,Sarin SK

更新日期：2008-07-01 00:00:00

abstract：:In addition to cholecystokinin, other hormones have been suggested to be involved in regulation of postprandial gallbladder contraction. We aimed to evaluate effects of growth hormone (GH) on gallbladder contractility and cholecystokinin release. Gallbladder and gastric emptying (by ultrasound) and cholecystokinin rel...

journal_title：Digestive diseases and sciences

authors： Moschetta A,Twickler TB,Rehfeld JF,van Ooteghem NA,Cabezas MC,Portincasa P,van Berge-Henegouwen GP,van Erpecum KJ

更新日期：2004-03-01 00:00:00

abstract：:The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner's glands was investigated in rats. Secretin increased volume secretion and the median output of EGF rose from 720 fmol/5 hr (total range 460-1320) in controls to 2065 fmol/5 hr (total range 1560-2730) at a dose of 50 pmo...

journal_title：Digestive diseases and sciences

authors： Olsen PS,Kirkegaard P,Poulsen SS,Nexø E

更新日期：1994-10-01 00:00:00

abstract：:The CCK-A (cholecystokinin-A) receptor is selectively expressed by human pancreatic adenocarcinomas, suggesting a possible role in pancreatic tumorigenesis. In animals, pancreatic CCK receptor expression varies during ontogeny and neoplastic transformation. This study examined the temporal expression of CCK receptors ...

journal_title：Digestive diseases and sciences

authors： Weinberg DS,So C,Ruggeri B,Biswas S,Barber M,Waldman S

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:While the short-term benefits of exclusive enteral nutrition (EEN) for induction of remission in children with Crohn's disease (CD) are well documented, the longer-term outcomes are less clear. AIM:This retrospective study aimed to ascertain the outcomes for up to 24 months following EEN in a group of child...

journal_title：Digestive diseases and sciences

authors： Lambert B,Lemberg DA,Leach ST,Day AS

更新日期：2012-08-01 00:00:00

abstract：:Bile acids, such as deoxycholic acid (DC), are known to mediate some of their actions by differentially activating various protein kinase C (PKC) isoforms. This study confirms that DC induces apoptosis in gastric epithelial cells through PARP and caspase cascade activation, and examined the role of PKC in DC-induced a...

journal_title：Digestive diseases and sciences

authors： Redlak MJ,Power JJ,Miller TA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:To explore the CT signs which permit estimation of clinically severe portal hypertension (PH) [≥ 12 of hepatic vein pressure gradient (HVPG)]. METHODS:One-hundred and seven consecutive patients who underwent HVPG measurement in the PH group and 52 controls were included. The diameters of main portal...

journal_title：Digestive diseases and sciences

authors： Lee JY,Kim TY,Jeong WK,Kim Y,Kim J,Kim KW,Kim YH,Sohn JH

更新日期：2014-09-01 00:00:00

abstract：:Because of marked improvement in diagnosis and management, cystic fibrosis is now more frequently noted in young adults, many of whom have only mild clinical forms. Pancreatitis is a known complication of cystic fibrosis and may occur at any time in the course of the disease; in rare instances, pancreatitis is the fir...

journal_title：Digestive diseases and sciences

authors： Masaryk TJ,Achkar E

更新日期：1983-10-01 00:00:00

abstract：:Lichen planus is a common mucocutaneus disorder that rarely involves the esophagus. We report two challenging cases presenting with recurrent dysphagia originally suspected due to gastroesophageal reflux. Subsequent evaluation revealed peculiar endoscopic findings of desquamative esophagitis leading to the diagnosis o...

journal_title：Digestive diseases and sciences

authors： Ukleja A,DeVault KR,Stark ME,Achem SR

更新日期：2001-10-01 00:00:00

abstract：:Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

journal_title：Digestive diseases and sciences

authors： Ainley EJ,Winwood PJ,Begley JP

更新日期：2005-07-01 00:00:00

abstract：:A sustained increase in cytosolic Ca2+ can damage gastric mucosal cells. The present study has examined the role of Ca2+ in thromboxane B2 (TXB2)-mediated damage of rabbit isolated gastric mucosal cells. Cells were isolated from rabbit oxyntic mucosa by collagenase-EDTA digestion. Cell metabolic activity and cell dama...

journal_title：Digestive diseases and sciences

authors： Wong HM,Soper BD,Tepperman BL

更新日期：1995-09-01 00:00:00

abstract：:Canine and human exocrine pancreatic secretion into the duodenum during fasting is cyclical and related to intestinal motility. To characterize the composition of pure pancreatic juice during the cyclically recurring sequence of propagated motor events (interdigestive motor complex) and to establish whether pancreatic...

journal_title：Digestive diseases and sciences

authors： Keane FB,Dozois RR,Go VL,Dimagno EP

更新日期：1981-07-01 00:00:00

abstract：:The present study aimed to investigate the role of nitric oxide on the oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, a nitric oxide donor, sodium nitroprusside, and superoxide dismutase were...

journal_title：Digestive diseases and sciences

authors： Kim H,Kim KH

更新日期：1998-05-01 00:00:00

abstract：:Theoretically, relative distal common bile duct obstruction due to sphincter of Oddi dysfunction may be a cause of poor gallbladder evacuation observed on quantitative cholescintigraphy. In this study, the relationship of sphincter of Oddi dysfunction to the gallbladder ejection fraction by quantitative cholescintigra...

journal_title：Digestive diseases and sciences

authors： Ruffolo TA,Sherman S,Lehman GA,Hawes RH

更新日期：1994-02-01 00:00:00

abstract：:Biomagnetic measurements are based on the noninvasive recording of magnetic signals produced by biological sources such as nervous system and muscle. The aim of this study was to obtain multichannel magnetic field recordings from the human gastrointestinal tract and to localize the sources of these signals three-dimen...

journal_title：Digestive diseases and sciences

authors： Allescher HD,Abraham-Fuchs K,Dunkel RE,Classen M

更新日期：1998-04-01 00:00:00

abstract：:A 65-year-old man with Crohn's disease died of acute myeloblastic leukemia after treatment for 11.8 years with 6-mercaptopurine, 1.5 mg/kg/day (100 mg/day). On cytogenetic analysis, most of the malignant bone marrow cells had deletion of chromosome 7, the most frequently reported cytogenetic abnormality in chemotherap...

journal_title：Digestive diseases and sciences

authors： Heizer WD,Peterson JL

更新日期：1998-08-01 00:00:00

abstract：:In a subset of patients with gastroesophageal reflux disease (GERD), symptoms persist in spite of proton pump inhibitor (PPI) therapy. Endoscopic gastroplication (EG) was reported to provide a novel therapeutic option in GERD. To evaluate symptomatic and objective outcome of EG in PPI refractory GERD, consecutive GERD...

journal_title：Digestive diseases and sciences

authors： Arts J,Lerut T,Rutgeerts P,Sifrim D,Janssens J,Tack J

更新日期：2005-02-01 00:00:00

abstract：:While transilluminating guinea pig gastric wall, we noticed foci of irregular compression of submucosal veins and arteries, featuring parallel bands across arteries, with complete cessation of blood flow, mucosal pallor, and shrinkage of the area. Other features demonstrated that this was not due to artifactual pressu...

journal_title：Digestive diseases and sciences

authors： Piasecki CK,Thrasivoulou C

更新日期：1993-07-01 00:00:00

abstract：:We retrospectively reviewed the role of ursodeoxycholic acid in infants having nonsurgical cholestasis attending the Hepatology Clinic, New Children Hospital, Cairo University, Egypt, from 1985 until 2005. Files of 496 infants with neonatal hepatitis and 97 with intrahepatic bile duct paucity were included; of them 24...

journal_title：Digestive diseases and sciences

authors： Kotb MA

更新日期：2009-10-01 00:00:00

abstract：:Recent data would limit indications for serum CEA measurement primarily to follow-up of resected colonic malignancy, yet physician attitude and usage patterns may lag far behind current findings. This discrepancy was investigated at our institution, where more than 1100 CEAs costing $71,000 are ordered each year. Of 4...

journal_title：Digestive diseases and sciences

authors： Vest SL,Roche JK

更新日期：1982-04-01 00:00:00