Efficacy of daily induction dosing vs standard thrice weekly dosing of interferon-alpha2B for initial treatment of chronic hepatitis C.

abstract：:Gastritis caused by Helicobacter pylori (HP) is common in patients with nonulcer dyspepsia (NUD), but an etiologic relationship between the histologic lesion and clinical symptoms is unproven. HP is inhibited by bismuth subsalicylate (BSS), a traditional remedy for dyspeptic complaints. The aim of this study was to as...

journal_title：Digestive diseases and sciences

authors： Marshall BJ,Valenzuela JE,McCallum RW,Dooley CP,Guerrant RL,Cohen H,Frierson HF Jr,Field LG,Jerdack GR,Mitra S

更新日期：1993-09-01 00:00:00

abstract：:Peptide YY (PYY) is an important modulator of stimulated pancreatic exocrine secretion. PYY acts proximal to the acinar cell but the exact site and mechanism of action are unknown. The aim of the present study is to determine the pathway through which PYY exerts its effect on the exocrine pancreas in awake rats under ...

journal_title：Digestive diseases and sciences

authors： Deng X,Guarita DR,Wood PG,Kriess C,Whitcomb DC

更新日期：2001-01-01 00:00:00

abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...

journal_title：Digestive diseases and sciences

authors： Heresbach D,Bretagne JF,Raoul JL,Moisan A,Siproudhis L,Devillers A,Gosselin M

更新日期：1993-09-01 00:00:00

abstract：:We retrospectively evaluated clinical factors affecting long-term survival after treatment for hepatocellular carcinoma (HCC) to predict the reliability of the prognosis of patients with HCC. We analyzed 157 patients who received treatment for HCC. The prognostic index (PI) was evaluated using the Cox regression model...

journal_title：Digestive diseases and sciences

authors： Kogo M,Kano A,Kiuchi Y,Mitamura K,Yoneyama K

更新日期：2007-09-01 00:00:00

abstract：:The perception that chronic hepatitis C is an asymptomatic disease contrasts with many studies that show a strong association between chronic hepatitis C, hepatocellular cancer, and fatal liver disease. In order to resolve these issues, it is logical to directly evaluate the quality of life in patients with chronic he...

journal_title：Digestive diseases and sciences

authors： Carithers RL Jr,Sugano D,Bayliss M

更新日期：1996-12-01 00:00:00

abstract：INTRODUCTION:Increased nonacid reflux is diagnosed in a subgroup of patients with gastroesophageal reflux disease who often present with reflux symptoms refractory to proton-pump inhibitor therapy. Despite the prevalence of this condition, the management approach for patients with increased nonacid reflux can often be ...

journal_title：Digestive diseases and sciences

authors： Reddy CA,Watts L,Baker JR,Chen JW

更新日期：2020-05-23 00:00:00

abstract：:Signet ring carcinoma of the pancreas is rare. We report a case which was remarkable for (1) diffuse, infiltrating growth which suggested chronic pancreatitis at laparotomy, and (2) an associated very high circulating carcinoembryonic antigen (CEA) level of 6400 ng/ml. The case report and autopsy are presented. Twelve...

journal_title：Digestive diseases and sciences

authors： Tracey KJ,O'Brien MJ,Williams LF,Klibaner M,George PK,Saravis CA,Zamcheck N

更新日期：1984-06-01 00:00:00

abstract：:Sulfated and unsulfated bile acid composition was studied in serum and bile in 10 patients with alcoholic cirrhosis. Samples, collected before and 2 months after portacaval anastomosis, were analyzed using a gaschromatographic method. Mean total serum bile acid levels rose from 32.0 +/- 5.3 (SE) mumol/liter before to ...

journal_title：Digestive diseases and sciences

authors： Capocaccia L,Attili AF,Cantafora A,Bracci F,Paciscopi L,Puoti C,Pièche U,Angelico M

更新日期：1981-06-01 00:00:00

abstract：:Five healthy young adults developed an acute self-limiting ulcerative esophagitis. Two had definite evidence of herpes virus being present and a third one had appropriate changes in herpes simplex viral titer. All cases followed a characteristic and similar course consisting of sudden onset of odynophagia, multiple di...

journal_title：Digestive diseases and sciences

authors： Springer DJ,DaCosta LR,Beck IT

更新日期：1979-07-01 00:00:00

abstract：:Ceramide plays an important role in regulating cell proliferation and apoptosis. Recent studies indicate that generation of ceramide in the intestine from sphingomyelin hydrolysis may be implicated in colon cancer development. The enzymes that catalyze the further hydrolysis of ceramide in the intestine have, however,...

journal_title：Digestive diseases and sciences

authors： Lundgren P,Nilsson A,Duan RD

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Fulminant hepatic failure (FHF) is a devastating syndrome, which sometimes results in death or liver transplantation, in which inflammation would aggravate the development of fetuin-A which would act as an anti-inflammatory factor and may be an available approach to attenuate FHF. AIMS:The purpose of this s...

journal_title：Digestive diseases and sciences

authors： Zhang P,Shen H,Huang J,Wang H,Zhang B,Zhou R,Zhong B,Fan X

更新日期：2014-08-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to investigate and compare the specificity, sensitivity, and area under curve (AUC) of the lactulose/mannitol ratio, lactulose/creatinine ratio, and lactulose recovery and their diagnostic value for intestinal permeability assessment within the absorption lactulose/mannitol (L/M...

journal_title：Digestive diseases and sciences

authors： Dastych M,Dastych M Jr,Novotná H,Cíhalová J

更新日期：2008-10-01 00:00:00

abstract：:Rabeprazole achieves more potent acid suppression than other proton pump inhibitors. Therefore it is administered at reduced as well as high dosages in eradication therapy for Helicobacter pylori; however, there is incomplete assessment of the efficacy of a reduced dosage of rabeprazole as might be employed in therapy...

journal_title：Digestive diseases and sciences

authors： Shimatani T,Inoue M,Kuroiwa T,Xu J,Tazuma S,Horikawa Y,Nakamura M

更新日期：2005-07-01 00:00:00

abstract：:Transverse myelitis (TM) as a manifestation of an autoimmune disorder is relatively rare. In Sjogren's syndrome (SS), the occurrence of TM is remarkably uncommon. Only three cases have been reported associated with primary biliary cirrhosis (PBC). Here we report the fourth case of TM occurring in association with SS a...

journal_title：Digestive diseases and sciences

authors： Anantharaju A,Baluch M,Van Thiel DH

更新日期：2003-04-01 00:00:00

abstract：:Telomerase acitivity can be induced in human B lymphocytes by in vitro stimulation of their antigen receptors. To determine whether telomerase activity is induced in vivo, we analyzed telomerase activity in B lymphocytes from the mesenteric lymph nodes of patients with inflammatory bowel disease (IBD), whose lymph nod...

journal_title：Digestive diseases and sciences

authors： Takagi S,Kinouchi Y,Chida M,Hiwatashi N,Noguchi M,Takahashi S,Shimosegawa T

更新日期：2003-10-01 00:00:00

abstract：:Our purpose was to determine if the presence of duodenal diverticula predisposes to the development of pancreaticobiliary disease. Between May 1999 and February 2001, 381 patients were examined by endoscopic retrograde cholangiopancreaticography. Of these patients, 51 had periampullary diverticula. In 27 patients the ...

journal_title：Digestive diseases and sciences

authors： Yildirgan MI,Başoğlu M,Yilmaz I,Atamanalp SS,Balik AA,Aydinli B,Oztürk G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Accumulating evidence has indicated that variations of mitochondrial DNA (mtDNA) content may affect the susceptibility to hepatocellular carcinoma (HCC). However, no study has been conducted to evaluate the association of circulating mtDNA content and the risk of liver cirrhosis, a leading cause of ...

journal_title：Digestive diseases and sciences

authors： Wang C,Hann HW,Hann RS,Wan S,Myers RE,Ye Z,Xing J,Yang H

更新日期：2015-06-01 00:00:00

abstract：:To investigate the role of heredity in alcoholic pancreatitis, an HLA typing study has been performed. Patients with alcoholic pancreatitis exhibited an increased frequency of HLA Bw 39 when compared with the general population [13.6% vs 3.3%, P (corrected) less than 0.02; relative risk 4.7]. Alcoholics without pancre...

journal_title：Digestive diseases and sciences

authors： Wilson JS,Gossat D,Tait A,Rouse S,Juan XJ,Pirola RC

更新日期：1984-08-01 00:00:00

abstract：:Gas within the stomach wall is a rare occurrence. A case of intramural gas is presented. When air or gas is seen within the gastric wall on x-ray, gastric emphysema, emphysematous gastritis, or pneumatosis intestinalis is diagnosed. These classifications have become vague and contradictory. Gas in the gastric wall can...

journal_title：Digestive diseases and sciences

authors： Kussin SZ,Henry C,Navarro C,Stenson W,Clain DJ

更新日期：1982-10-01 00:00:00

abstract：:We present a case of pancreatic ascites. The diagnosis was strongly suspected on the basis of ascitic fluid analysis and was confirmed by observation of pancreatic duct contrast leakage at endoscopic retrograde pancreatography (ERP). Computed tomography was not helpful in this case. For localization and final confirma...

journal_title：Digestive diseases and sciences

authors： Kuo YC,Wu CS

更新日期：1994-05-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) activity has been associated with mucosal growth and injury, yet, little information is available on ODC activity during gastric ulcer healing. We measured ODC activity in the ulcer base submucosa and the surrounding mucosa at 1 cm and 2 cm and assessed ulcer surface healing and a histolo...

journal_title：Digestive diseases and sciences

authors： Marcuard SP,Silverman JF,Finley JL,Seidel ER

更新日期：1992-07-01 00:00:00

abstract：:Clinical observations reveal that alcohol intake is associated with an increase in upper gastrointestinal hemorrhage requiring hospitalization and that nitroglycerin or long-acting nitrates lower this risk. Nitroglycerin, a gastric vasodilator that can increase gastric fluid volume, protects the rodent stomach against...

journal_title：Digestive diseases and sciences

authors： Leung FW,Chan CC

更新日期：2007-11-01 00:00:00

abstract：:A 65-year-old man with Crohn's disease died of acute myeloblastic leukemia after treatment for 11.8 years with 6-mercaptopurine, 1.5 mg/kg/day (100 mg/day). On cytogenetic analysis, most of the malignant bone marrow cells had deletion of chromosome 7, the most frequently reported cytogenetic abnormality in chemotherap...

journal_title：Digestive diseases and sciences

authors： Heizer WD,Peterson JL

更新日期：1998-08-01 00:00:00

abstract：:It is known that calcium ion has an important role in the cellular function. For this reason, calcium channel blockers may have a protective action against gastric injury which is induced by various stimuli. In this study, the influence of mibefradil on ethanol-induced gastric injury was investigated in rats. Mibefrad...

journal_title：Digestive diseases and sciences

authors： Bilici D,Banoğlu ZN,Kiziltunç A,Avci B,Ciftçioğlu A,Bilici S

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are widely prescribed to treat gastrointestinal diseases. However, concerns have been raised regarding their long-term use. Gastric acid suppression may decrease iron absorption, and it remains uncertain whether iron-deficiency anemia may result from chronic PPI therapy. AIMS:W...

journal_title：Digestive diseases and sciences

authors： Sarzynski E,Puttarajappa C,Xie Y,Grover M,Laird-Fick H

更新日期：2011-08-01 00:00:00

abstract：:The potential effect of recombinant human interleukin-11 (rhIL-11) on trinitrobenzene sulfonic acid (TNB)-induced colitis was investigated in rats. Intrarectal TNB (40 mg in 0.25 ml 40% ethanol) produced significant ulcerative colitis. The lesions were most severe at three days after TNB instillation, and then decline...

journal_title：Digestive diseases and sciences

authors： Qiu BS,Pfeiffer CJ,Keith JC Jr

更新日期：1996-08-01 00:00:00

abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

journal_title：Digestive diseases and sciences

authors： Eaves ER,Hansky J

更新日期：1987-01-01 00:00:00

abstract：:Fractional systemic bioavailability of orally administered drugs was found to be unexpectedly low in liver cirrhosis, even after surgical portal-systemic shunting. Fecal loss or intestinal first-pass elimination were assumed to explain the finding. In this paper we evaluated alternative pathophysiological interpretati...

journal_title：Digestive diseases and sciences

authors： Molino G,Avagnina P,Garrone C,Sansoè G,Degerfeld MM,Peretti P,Tinivella M,Bianco S

更新日期：2001-03-01 00:00:00

abstract：:Intravenous lidocaine was infused at 0.82 ml/min in a concentration of 1.2 mg/ml (2.3 mg/kg) for 120 min in awake chair-restrained baboons (Papio anubis), and measurements of esophageal peristalsis and LES pressure were compared before and after lidocaine or control infusions. Lidocaine produced a progressive and sign...

journal_title：Digestive diseases and sciences

authors： Sinar DR,Carey LC,Cordova C,Fletcher JR,Castell DO

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The influence of direct-acting antivirals (DAAs) on chronic hepatitis C (CHC)-related hepatocellular carcinoma (HCC) remains controversial. We investigated the effect of eradicating CHC using DAAs on treatment outcomes in patients with CHC-related HCC treated with transarterial chemoembolization (TA...

journal_title：Digestive diseases and sciences

authors： Hyun HK,Cho EJ,Park SY,Hong YM,Kim SS,Kim HY,Heo NY,Park JG,Sinn DH,Kang W,Jeong SW,Song MJ,Park H,Lee D,Lee YS,Cho SB,An CS,Rhee HJ,Lee HW,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Lee JH,Yu SJ,Kim YJ,Yoo

更新日期：2020-08-28 00:00:00