Redox regulation of interleukin-8 expression in MKN28 cells.

abstract：:The value of a "bread-barium" swallow for diagnosis of disordered esophageal motility was examined in 53 patients, 20 of whom complained of dysphagia, 20 retrosternal chest pain, and 13 heartburn; a further 19 subjects served as controls. Esophageal manometry in the patients with dysphagia and chest pain revealed majo...

journal_title：Digestive diseases and sciences

authors： Davies HA,Evans KT,Butler F,McKirdy H,Williams GT,Rhodes J

更新日期：1983-12-01 00:00:00

abstract：:Hepatic steatosis is a recognized feature of hepatitis C viral infection, particularly in genotype 3. The demographics and the associations contributing to moderate to severe steatosis in genotype 3 are not very well studied. The aim of this study is to determine the demographics and association of steatosis with fibr...

journal_title：Digestive diseases and sciences

authors： Sharma P,Balan V,Hernandez J,Rosati M,Williams J,Rodriguez-Luna H,Schwartz J,Harrison E,Anderson M,Byrne T,Vargas HE,Douglas DD,Rakela J

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:The lactulose breath test (LBT) and gastroenterocolonic scintigraphy (GECS) can both be used to measure orocecal transit time (OCTT). The aims of this study were (1) to measure OCTT by LBT and GECS and (2) to determine whether lactulose alters orocecal transit. METHODS:Eight normal subjects underwent simult...

journal_title：Digestive diseases and sciences

authors： Miller MA,Parkman HP,Urbain JL,Brown KL,Donahue DJ,Knight LC,Maurer AH,Fisher RS

更新日期：1997-01-01 00:00:00

abstract：:In the pathogenesis of gastroesophageal reflux disease (GERD), gastric acid is considered to be one of the most important factors, but little is known about the degree of gastric acid secretion in GERD patients. In this study, we evaluated it in GERD patients and control subjects by 24-h intragastric pH, and serologic...

journal_title：Digestive diseases and sciences

authors： Shimatani T,Inoue M,Harada N,Horikawa Y,Nakamura M,Tazuma S

更新日期：2004-05-01 00:00:00

abstract：:To investigate a potential new treatment for gastric Helicobacter pylori infection, we have examined the use of the natural antibiotic lactoferrin, found in bovine milk, for activity against Helicobacter species both in vitro and in vivo. Lactoferrin was bacteriostatic to H. pylori when cultured at concentrations > or...

journal_title：Digestive diseases and sciences

authors： Dial EJ,Hall LR,Serna H,Romero JJ,Fox JG,Lichtenberger LM

更新日期：1998-12-01 00:00:00

abstract：:Microvesicular steatosis is a potentially severe manifestation of valproic acid hepatotoxicity due to an acquired impairment of mitochondrial function. Tests currently used to investigate mitochondrial fonction are cumbersome and cannot be used routinely. We report on a noninvasive breath test using [13C]methionine fo...

journal_title：Digestive diseases and sciences

authors： Spahr L,Negro F,Rubbia-Brandt L,Marinescu O,Goodman K,Jordan M,Frossard JL,Hadengue A

更新日期：2001-12-01 00:00:00

abstract：:We have previously reported impressive results in using a gonadotropin-releasing hormone analog, leuprolide acetate (Lupron), in the treatment of moderate to severe symptoms (especially abdominal pain and nausea) in patients with functional bowel disease (FBD). Pain is the hallmark of patients with FBD, and there is n...

journal_title：Digestive diseases and sciences

authors： Mathias JR,Clench MH,Abell TL,Koch KL,Lehman G,Robinson M,Rothstein R,Snape WJ

更新日期：1998-06-01 00:00:00

abstract：:The CCK-A (cholecystokinin-A) receptor is selectively expressed by human pancreatic adenocarcinomas, suggesting a possible role in pancreatic tumorigenesis. In animals, pancreatic CCK receptor expression varies during ontogeny and neoplastic transformation. This study examined the temporal expression of CCK receptors ...

journal_title：Digestive diseases and sciences

authors： Weinberg DS,So C,Ruggeri B,Biswas S,Barber M,Waldman S

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIM:Second harmonic generation (SHG) is a novel imaging technology that could provide optical biopsy during endoscopy with advantages over current technology. SHG has the unique ability to evaluate the amount of extracellular matrix collagen protein and its alignment. METHODS:Hematoxylin- and eosin-stai...

journal_title：Digestive diseases and sciences

authors： Birk JW,Tadros M,Moezardalan K,Nadyarnykh O,Forouhar F,Anderson J,Campagnola P

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Numerous experiments have shown that alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are present in cells of various cancer and can play role in carcinogenesis. In previous investigations we have found elevated levels of alcohol dehydrogenase class III activity in pancreatic cancer cells. It ca...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the inhibitory activity of selenium-enriched probiotics against pathogenic Escherichia coli (E. coli) in vitro and in vivo. Escherichia coli was co-cultured in vitro with each probiotic strain individually, and a mixture of the four strains and its population was counted at va...

journal_title：Digestive diseases and sciences

authors： Yang J,Huang K,Qin S,Wu X,Zhao Z,Chen F

更新日期：2009-02-01 00:00:00

abstract：:Detecting plasma protein loss from the stomach is quite difficult by measuring fecal alpha1-AT clearance because alpha1-AT is rapidly destroyed in the gastric juice at values below pH 3. We examined protein loss from the stomach using fecal alpha1-AT clearance with lansoprazole, a proton pump inhibitor. A 38-year-old ...

journal_title：Digestive diseases and sciences

authors： Takeda H,Nishise S,Furukawa M,Nagashima R,Shinzawa H,Takahashi T

更新日期：1999-11-01 00:00:00

abstract：:The macroscopic appearance of the liver after primary portal vein thrombosis often mimics cirrhosis, despite the absence of bridging fibrosis at histology. The purpose of this study was to describe unique morphologic changes of the liver after portal venous thrombosis. A retrospective review was performed to find pati...

journal_title：Digestive diseases and sciences

authors： Tublin ME,Towbin AJ,Federle MP,Nalesnik MA

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Probe-based confocal laser endomicroscopy (pCLE) has enabled in vivo histopathology by obtaining high resolution images of the mucosal layers of the gastrointestinal tract. For indeterminate bile duct strictures, biopsy, cytologic brushing and needle aspiration have low levels of diagnostic accuracy. AIM:Th...

journal_title：Digestive diseases and sciences

authors： Talreja JP,Sethi A,Jamidar PA,Singh SK,Kwon RS,Siddiqui UD,Sawhney M,Bakhru MR,Gaidhane M,Kline P,Sauer BG,Kahaleh M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:A prolific trend currently designates endoscopic ultrasonography (EUS) literature. We aimed to record all EUS-studies published during the past decade and evaluate them in terms of scientific quality, creating a stratification based on levels of evidence (LE). METHODS:All articles on EUS published ...

journal_title：Digestive diseases and sciences

authors： Fusaroli P,Kypraios D,Eloubeidi MA,Caletti G

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:A role of an altered dietary pattern (e.g., a diet rich in sugar) but also alterations at the level of the intestinal barrier have repeatedly been discussed to be involved in the development and progression of nonalcoholic fatty liver disease (NAFLD). AIMS:To determine if the nutritional intake, intestinal ...

journal_title：Digestive diseases and sciences

authors： Volynets V,Küper MA,Strahl S,Maier IB,Spruss A,Wagnerberger S,Königsrainer A,Bischoff SC,Bergheim I

更新日期：2012-07-01 00:00:00

abstract：:Hilar cancers carry a dismal prognosis. Palliation of obstructive jaundice in patients with hilar cancer can be achieved by either surgical or nonsurgical means. Selection of the appropriate palliative measures is a challenging problem. Segmental bilioenteric anastomosis procedures were performed on 19 patients with h...

journal_title：Digestive diseases and sciences

authors： Yilmaz S,Kirimlioglu V,Katz DA,Caglikulekci M,Yilmaz M

更新日期：2000-08-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

journal_title：Digestive diseases and sciences

authors： Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

更新日期：2008-01-01 00:00:00

abstract：:The main pancreatic duct epithelium acts as a barrier to the diffusion of molecules from the duct lumen into pancreatic acinar and interstitial tissue. We studied sequential ultrastructural characteristics of the loss of epithelial barrier function in the cat using lanthanum, an electron-opaque tracer, following perfu...

journal_title：Digestive diseases and sciences

authors： Arendt T

更新日期：1991-01-01 00:00:00

abstract：:Na/H exchanger-1 (NHE-1) isoform regulates intracellular pH and protects the esophageal mucosa. These functions are compromised in gastroesophageal reflux disease (GERD); however, the role and the underlying mechanism of NHE-1 regulation are obscure. To address this issue, NHE-1 protein and mRNA levels were measured b...

journal_title：Digestive diseases and sciences

authors： Siddique I,Khan I

更新日期：2003-09-01 00:00:00

abstract：:The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner's glands was investigated in rats. Secretin increased volume secretion and the median output of EGF rose from 720 fmol/5 hr (total range 460-1320) in controls to 2065 fmol/5 hr (total range 1560-2730) at a dose of 50 pmo...

journal_title：Digestive diseases and sciences

authors： Olsen PS,Kirkegaard P,Poulsen SS,Nexø E

更新日期：1994-10-01 00:00:00

abstract：:When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

journal_title：Digestive diseases and sciences

authors： Kumar R,Nagubandi S,Londowski JM

更新日期：1981-03-01 00:00:00

abstract：:The role of carbonic anhydrase in the process of proximal duodenal mucosal bicarbonate secretion was investigated in the guinea pig. In a series of experiments in vivo, the duodenum was perfused with 24 mmol/liter NaHCO3 solution (+ NaCl for isotonicity) to ensure that active duodenal HCO3- secretion against a concent...

journal_title：Digestive diseases and sciences

authors： Muallem R,Reimer R,Odes HS,Schwenk M,Beil W,Sewing KF

更新日期：1994-05-01 00:00:00

abstract：:Lansoprazole, a proton pump inhibitor, exerts prominent antiulcer activity via both antisecretory and mucosal protective actions. Although the antisecretory action has been explained by inactivation of (H+, K+)-ATPase in parietal cells, the mode of mucosal protective action remains to be elucidated. In the present stu...

journal_title：Digestive diseases and sciences

authors： Inada I,Satoh H

更新日期：1996-04-01 00:00:00

abstract：:The frequent association of stromal tumors with neurofobromatosis raises high suspicion of a possible correlation between the two entities. The aim of this study was to analyze clinicopathologic features of patients with concomitant neurofibromatosis and gastrointestinal stromal tumors and to discuss the molecular bas...

journal_title：Digestive diseases and sciences

authors： Cheng SP,Huang MJ,Yang TL,Tzen CY,Liu CL,Liu TP,Hsiao SC

更新日期：2004-08-01 00:00:00

abstract：:The aim of this study was to compare the effect on HCV RNA levels of using induction dosing with 5 MU interferon-alpha2b (IFN) given daily for four weeks followed by 5 MU IFN given three times a week (TIW) for 44 weeks vs standard noninduction TIW dosing of 5 MU IFN for 48 weeks. We randomly assigned 135 patients with...

journal_title：Digestive diseases and sciences

authors： Gonzalez HJ,Ho SB,Gross JB,Peine C,McKee D,Smith T,Midwest Hepatitis Study Group.

更新日期：2002-04-01 00:00:00

abstract：:Five cases of granular cell tumor of the esophagus are reported. In four cases, the tumor was an asymptomatic, incidental finding. In one case, a larger granular cell tumor presented with dysphagia and required local surgical excision. Long-term follow-up in three cases revealed no evidence of tumor progression. Esoph...

journal_title：Digestive diseases and sciences

authors： Brady PG,Nord HJ,Connar RG

更新日期：1988-10-01 00:00:00

abstract：:The evaluation of suspected esophageal chest pain is frustrating because of difficulty in clearly implicating the esophagus. Balloon distention was considered as a new provocative test in the esophagus because it has been shown to safely produce pain in other hollow gastrointestinal organs. Studies were performed in 5...

journal_title：Digestive diseases and sciences

authors： Barish CF,Castell DO,Richter JE

更新日期：1986-12-01 00:00:00

abstract：:This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healin...

journal_title：Digestive diseases and sciences

authors： Di Febo G,Miglioli M,Calò G,Biasco G,Luzza F,Gizzi G,Cipollini F,Rossi A,Barbara L

更新日期：1985-02-01 00:00:00

abstract：:H. pylori may colonize columnar-lined esophagus, although an etiologic role in esophageal adenocarcinoma is unproven. H. pylori can adhere to intestinal metaplasia in the stomach. This study was designed to examine if H. pylori adheres to specialized intestinal metaplasia in columnar-lined esophagus. Esophageal biopsi...

journal_title：Digestive diseases and sciences

authors： Sharma VK,Demian SE,Taillon D,Vasudeva R,Howden CW

更新日期：1999-06-01 00:00:00