Granular cell tumor of the esophagus: natural history, diagnosis, and therapy.

abstract：BACKGROUND AND AIM:Upper gastrointestinal (UGI) symptoms are common; however, the role of Helicobacter pylori and gastric corpus atrophy in the generation of these symptoms is controversial. The aim of this study was to determine the risk factors for UGI symptoms in adults in an endemic area of H. pylori infection. ME...

journal_title：Digestive diseases and sciences

authors： Lee SP,Lee SY,Kim JH,Sung IK,Park HS,Shim CS

更新日期：2017-06-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is caused by a mechanically defective lower esophageal sphincter (LES) and may be worsened by impaired esophageal peristalsis. The aim of this study was to evaluate the efficacy of medical treatment depending on the function of the LES and esophageal peristalsis. We studied 128 G...

journal_title：Digestive diseases and sciences

authors： Klaus A,Gadenstaetter M,Mühlmann G,Kirchmayr W,Profanter C,Achem SR,Wetscher GJ

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The role of oxidative stress in inflammatory bowel diseases (IBD) has been extended lately from a simple consequence of inflammation to a potential etiological factor, but the data are still controversial. Active disease has been characterized before by an enhanced production of reactive oxygen species and t...

journal_title：Digestive diseases and sciences

authors： Achitei D,Ciobica A,Balan G,Gologan E,Stanciu C,Stefanescu G

更新日期：2013-05-01 00:00:00

abstract：:Alterations in insulin and glucagon levels might account for the plasma amino acid imbalance of cirrhotics. In order to verify this hypothesis we evaluated basal insulin, glucagon, branched-chain amino acids, aromatic amino acids, and free tryptophan in 13 controls and 37 cirrhotics divided on the basis of their menta...

journal_title：Digestive diseases and sciences

authors： Marchesini G,Forlani G,Zoli M,Angiolini A,Scolari MP,Bianchi FB,Pisi E

更新日期：1979-08-01 00:00:00

abstract：:The major heat shock protein, HSP70, is known to be involved in cytoprotection against environmental stresses mediated by their function as a "molecular chaperone." However, the influence of HSP70 on gastric mucosal healing under physical stimulation or stress is not completely understood. Rat gastric mucosal cells (R...

journal_title：Digestive diseases and sciences

authors： Odashima M,Otaka M,Matsuhashi T,Jin M,Horikawa Y,Ohba R,Itoh H,Watanabe S

更新日期：2007-11-01 00:00:00

abstract：:An association between hypothermia and gastric ulceration has been reported in rats in cervical cord section and in restraint models. The present study was designed to determine this relationship in cervical and in lumbar cord sectioned Sprague-Dawley rats. Ambient temperatures were varied by placing the sectioned ani...

journal_title：Digestive diseases and sciences

authors： Sigman HH,Gillich A

更新日期：1981-01-01 00:00:00

abstract：:The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

journal_title：Digestive diseases and sciences

authors： Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Neuromediators produced by enteric nervous system regulate inflammatory processes via interacting with enteric immune system. Role of γ-aminobutyric acid (GABA), which is also a neuromediator, has been implicated in autoimmune diseases like multiple sclerosis, type 1 diabetes, and rheumatoid arthritis, where...

journal_title：Digestive diseases and sciences

authors： Aggarwal S,Ahuja V,Paul J

更新日期：2017-10-01 00:00:00

abstract：:Transient delayed gastric emptying is reported as a frequent complication following pancreas-preserving pancreaticoduodenectomy (PPW). We placed serosal electrodes on the stomach of a patient undergoing PPW. Myoelectric recordings were obtained postoperatively and correlated with simultaneous radionuclide liquid gastr...

journal_title：Digestive diseases and sciences

authors： Hocking MP,Harrison WD,Sninsky CA

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) are widely prescribed to treat gastrointestinal diseases. However, concerns have been raised regarding their long-term use. Gastric acid suppression may decrease iron absorption, and it remains uncertain whether iron-deficiency anemia may result from chronic PPI therapy. AIMS:W...

journal_title：Digestive diseases and sciences

authors： Sarzynski E,Puttarajappa C,Xie Y,Grover M,Laird-Fick H

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Amoxicillin, metronidazole, proton pump inhibitor, bismuth quadruple therapy had been shown to reliably achieve high eradication rates. The role of individual components remains undefined. AIM:To identify the additional benefit/role of bismuth in amoxicillin, metronidazole, proton pump inhibitor, bismuth qu...

journal_title：Digestive diseases and sciences

authors： Luo L,Ji Y,Yu L,Huang Y,Liang X,Graham DY,Lu H

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Subjects with fatty liver disease (FLD) can show increased hepatic 2-deoxy-2-((18)F)fluoro-D-glucose (FDG) uptake, but the role of hepatic inflammation has not been explored. AIMS:We investigated whether hepatic inflammatory response, as implicated by elevated serum markers, is associated with increased liv...

journal_title：Digestive diseases and sciences

authors： Hong SP,Noh TS,Moon SH,Cho YS,Lee EJ,Choi JY,Kim BT,Lee KH

更新日期：2014-03-01 00:00:00

abstract：:Minimal hepatic encephalopathy (MHE) is characterized by disturbance of mental state and neuromuscular function. To assess the clinical efficacy of acetyl-L: -carnitine (ALC) in the treatment of MHE, we performed a randomized, double-blind, placebo-controlled study administering ALC in cirrhotic patients with this dis...

journal_title：Digestive diseases and sciences

authors： Malaguarnera M,Gargante MP,Cristaldi E,Vacante M,Risino C,Cammalleri L,Pennisi G,Rampello L

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal algorithm to identify Lynch syndrome (LS) among patients with colorectal cancer (CRC) is unclear. The definitive test for LS, germline testing, is too expensive to be applied in all cases. Initial screening with the revised Bethesda Guidelines (RBG) cannot be applied in a considerable nu...

journal_title：Digestive diseases and sciences

authors： Gould-Suarez M,El-Serag HB,Musher B,Franco LM,Chen GJ

更新日期：2014-12-01 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant connective tissue disease caused by mutations in the type III collagen gene resulting in extreme tissue fragility. Affected individuals are at risk of dramatic and often fatal complications, mostly spontaneous arterial, uterine, or colonic ruptures. Phenoty...

journal_title：Digestive diseases and sciences

authors： Gelbmann CM,Köllinger M,Gmeinwieser J,Leser HG,Holstege A,Schölmerich J

更新日期：1997-08-01 00:00:00

abstract：:As recently described, Ki-1 anaplastic large cell lymphoma is a distinctive subtype of non-Hodgkin's lymphoma. We report a Ki-1 anaplastic large cell lymphoma of the duodenum in a 62-year-old man. He received modified CHOP therapy and was in complete remission at 18 months. To our knowledge, this is the first report o...

journal_title：Digestive diseases and sciences

authors： Yoshikawa I,Murata I,Tanaka Y,Kanagawa K,Tabaru A,Itoh H,Otsuki M

更新日期：1996-12-01 00:00:00

abstract：:Liver transplantation is the only effective treatment of familial amyloidotic polyneuropathy type I (FAP). The aim of the present investigation was to identify factors at the time of submission for transplantation that had impact on survival, with special reference to gastrointestinal disturbances. All 28 liver-transp...

journal_title：Digestive diseases and sciences

authors： Suhr O,Danielsson A,Rydh A,Nyhlin N,Hietala SO,Steen L

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Although a genetic component has been identified as a risk factor for developing inflammatory bowel disease, there is evidence that dietary factors also play a role in the development of this disease. AIMS:The aim of this study was to determine the effects of feeding a red meat diet with and without resista...

journal_title：Digestive diseases and sciences

authors： Le Leu RK,Young GP,Hu Y,Winter J,Conlon MA

更新日期：2013-12-01 00:00:00

abstract：:The efficacy of tiotidine, a new H2-receptor antagonist, in reducing nocturnal acid secretion of duodenal ulcer patients (N = 12, ages 21-60 years) was investigated. Different doses of tiotidine, 25, 50, 100, and 150 mg or placebo, were given as a single oral dose and acid secretion collected overnight. Tiotidine prod...

journal_title：Digestive diseases and sciences

authors： Valenzuela JE,Strecker RB,Douglas AP

更新日期：1981-05-01 00:00:00

abstract：:Rectally administered suspensions of 5-aminosalicylic acid (5-ASA) are topically effective in treating left-sided ulcerative colitis. The extent to which the contents of these enemas are distributed to inflamed mucosal linings has not previously been determined. This study was undertaken to validate a technique for la...

journal_title：Digestive diseases and sciences

authors： Vitti RA,Meyers F,Knight LC,Siegel JA,Malmud LS,Fisher RS

更新日期：1989-11-01 00:00:00

abstract：:This study was designed to determine the possible effects of omeprazole on human natural killer cells. Peripheral venous blood samples were taken from 20 peptic ulcer patients before and at the 14th and the 28th days of omeprazole treatment. Mononuclear cells were removed from blood and their capability of making conj...

journal_title：Digestive diseases and sciences

authors： Alkim H,Unal S,Okur H,Imir T

更新日期：2008-02-01 00:00:00

abstract：:A patient with congenital asucrasia was investigated using in vivo differential urinary disaccharide excretion. Impaired hydrolysis of sucrose and isomaltose, but normal lactase activity, were demonstrated and confirmed by in vitro estimation. The technique of differential disaccharide excretion can now be used to ass...

journal_title：Digestive diseases and sciences

authors： Maxton DG,Catt SD,Menzies IS

更新日期：1989-01-01 00:00:00

abstract：:Somatostatin analog SMS 201-995 causes a dose-related suppression of the release and/or action of several gastrointestinal hormones and impairs several anterior pituitary functions. Some patients with illness involving abnormal hormonal activity have responded to treatment with SMS 201-995, including resolution of sev...

journal_title：Digestive diseases and sciences

authors： Greenberg RN

更新日期：1991-12-01 00:00:00

abstract：:Impaired gallbladder emptying is one of the various factors suggested to be involved in the pathogenesis of gallstones. The present study was undertaken to determine whether gallbladder emptying, endogenous cholecystokinin (CCK) secretion, or their interrelation is altered in patients with gallstones. After intraduode...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Driessen WM,Geuskens LM,Lamers CB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic liver disease and is considered a profibrotic mediator due to its proliferative effect on cultured HSCs and ability to degrade normal liver matrix. Although associ...

journal_title：Digestive diseases and sciences

authors： Radbill BD,Gupta R,Ramirez MC,DiFeo A,Martignetti JA,Alvarez CE,Friedman SL,Narla G,Vrabie R,Bowles R,Saiman Y,Bansal MB

更新日期：2011-02-01 00:00:00

abstract：:We examined the effect of sildenafil, an inhibitor of phosphodiesterase subtype 5, that catalyzes hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP), on indomethacin-induced small-intestinal ulceration in rats and investigated the mechanism of this action, especially in relation to endogenous nitric oxide (NO)....

journal_title：Digestive diseases and sciences

authors： Kato N,Mashita Y,Kato S,Mitsufuji S,Yoshikawa T,Takeuchi K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Obesity and metabolic syndrome are risk factors for colorectal neoplasia (CRN). However, the association between metabolically healthy obese (MHO) or metabolically unhealthy non-obese (MUNO) status and the risk of CRN remains unclear. AIMS:We aimed to elucidate the association between MHO or MUNO status and...

journal_title：Digestive diseases and sciences

authors： Kim NH,Jung YS,Park JH,Park DI,Sohn CI

更新日期：2018-11-01 00:00:00

abstract：:Cholecystectomy is one of the commonest surgical procedures in the Western world, with more than half a million procedures performed annually in the United States alone. In recent years, studies of gallstone pathogenesis and gallbladder disease have increasingly focused on abnormal gallbladder motility in the pathogen...

journal_title：Digestive diseases and sciences

authors： Patankar R,Ozmen MM,Bailey IS,Johnson CD

更新日期：1995-11-01 00:00:00

abstract：:The main pancreatic duct epithelium acts as a barrier to the diffusion of molecules from the duct lumen into pancreatic acinar and interstitial tissue. We studied sequential ultrastructural characteristics of the loss of epithelial barrier function in the cat using lanthanum, an electron-opaque tracer, following perfu...

journal_title：Digestive diseases and sciences

authors： Arendt T

更新日期：1991-01-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00