Bone disease in vitamin D-deficient patients with Crohn's disease.

abstract：:An intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induces selective killing and rapid regeneration of Paneth cells, which have a large amount of zinc in their cytoplasmic granules. We examined the expression pattern of transforming growth factor (TGF) -alpha and TGF-beta1 in this regenera...

journal_title：Digestive diseases and sciences

authors： Seno H,Sawada M,Fukuzawa H,Morita Y,Takaishi S,Hiai H,Chiba T

更新日期：2001-05-01 00:00:00

abstract：:All cases of hepatolithiasis showed features of chronic proliferative cholangitis, and it has been speculated that the atypical glandular proliferation might be a precursor to overt cholangiocarcinoma. Proliferative cell nuclear antigen (PCNA) is a nuclear protein synthesized in the G1/S phase of the cell cycle and th...

journal_title：Digestive diseases and sciences

authors： Lee KT,Sheen PC

更新日期：1999-11-01 00:00:00

abstract：:The hepatic stimulatory substance (HSS) extracted from weanling rat livers was purified 381,000-fold using chromatographic techniques including nondissociating polyacrylamide gel electrophoresis (nondenaturing PAGE). The activity of this highly purified HSS, named Acr-F4, was assessed in two in vivo models. In 40% hep...

journal_title：Digestive diseases and sciences

authors： Francavilla A,Barone M,Van Thiel DH,Mazzaferro V,Prelich JG,Starzl TE

更新日期：1991-05-01 00:00:00

abstract：:Omentum was shown to exhibit angiogenic activity, but its role in healing of chronic gastric ulcers is unknown. This study was designed to compare the effects of omentum and basic fibroblast growth factor (bFGF), a potent angiogenic factor, on healing of chronic gastric ulcers in rats. Several series of rats with gast...

journal_title：Digestive diseases and sciences

authors： Konturek SJ,Brzozowski T,Majka I,Pawlik W,Stachura J

更新日期：1994-05-01 00:00:00

abstract：:Previous studies suggest that posture has relatively little effect on gastric emptying of high-nutrient liquids; these studies have, however, only assessed overall rates of gastric emptying, whereas gastric emptying is known to be predominantly a pulsatile phenomenon. In healthy subjects perceptions of appetite, such ...

journal_title：Digestive diseases and sciences

authors： Jones KL,O'Donovan D,Horowitz M,Russo A,Lei Y,Hausken T

更新日期：2006-08-01 00:00:00

abstract：:Alkaline sphingomyelinase (Alk-SMase) is a key enzyme in the intestinal tract for digestion of dietary sphingomyelin (SM), which generates lipid messengers with cell-cycle regulating effects. The enzyme is significantly decreased in ulcerative colitis and colon cancer. Based on this information, we wanted to investiga...

journal_title：Digestive diseases and sciences

authors： Andersson D,Kotarsky K,Wu J,Agace W,Duan RD

更新日期：2009-07-01 00:00:00

abstract：:Autoimmune hepatitis has a variable clinical phenotype, and the absence of conventional autoantibodies does not preclude its diagnosis or need for treatment. The goals of this review are to describe the frequency and nature of autoantibody-negative autoimmune hepatitis, indicate its outcome after corticosteroid treatm...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The relationship of gastric cancer to the presence of interleukin-8 (IL-8) 251 T/A has been reported with conflicting results. AIM:To further explore the association of IL-8 251 allele polymorphism with gastric cancer susceptibility. METHODS:We performed an extensive search of relevant studies and carried ...

journal_title：Digestive diseases and sciences

authors： Wang J,Pan HF,Hu YT,Zhu Y,He Q

更新日期：2010-07-01 00:00:00

abstract：:The aim of this study was to assess resting energy expenditure in patients with chronic pancreatitis; 33 patients with alcohol-related chronic pancreatitis (group 1: 13 normal weight, group 2: 20 underweight) and 11 undernourished patients without identifiable disease (group 3) were studied. Body composition was deter...

journal_title：Digestive diseases and sciences

authors： Hébuterne X,Hastier P,Péroux JL,Zeboudj N,Delmont JP,Rampal P

更新日期：1996-03-01 00:00:00

abstract：:Pancreaticopleural fistulas are a rare complication of pancreatitis. We report two cases from our institution and review 37 cases of pancreaticopleural fistulas identified in the literature. Endoscopic retrograde cholangiopancreatography was more sensitive compared to computed tomography in demonstrating pancreaticopl...

journal_title：Digestive diseases and sciences

authors： Oh YS,Edmundowicz SA,Jonnalagadda SS,Azar RR

更新日期：2006-01-01 00:00:00

abstract：:Because of marked improvement in diagnosis and management, cystic fibrosis is now more frequently noted in young adults, many of whom have only mild clinical forms. Pancreatitis is a known complication of cystic fibrosis and may occur at any time in the course of the disease; in rare instances, pancreatitis is the fir...

journal_title：Digestive diseases and sciences

authors： Masaryk TJ,Achkar E

更新日期：1983-10-01 00:00:00

abstract：:Both intracellular calcium ions and neural input are important in esophageal smooth muscle contraction. The aim of this study was to compare the effects of well-tolerated doses of the calcium-channel blocker, nifedipine (20 mg sublingually/buccally) with the anticholinergic, propantheline bromide (15 mg orally) and th...

journal_title：Digestive diseases and sciences

authors： Hongo M,Traube M,McCallum RW

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Fulminant hepatic failure (FHF) is a devastating syndrome, which sometimes results in death or liver transplantation, in which inflammation would aggravate the development of fetuin-A which would act as an anti-inflammatory factor and may be an available approach to attenuate FHF. AIMS:The purpose of this s...

journal_title：Digestive diseases and sciences

authors： Zhang P,Shen H,Huang J,Wang H,Zhang B,Zhou R,Zhong B,Fan X

更新日期：2014-08-01 00:00:00

abstract：:It has previously been shown that mucosal nitric oxide synthase (NOS) is involved in acid-induced duodenal mucosal alkaline secretion. The primary aim of the present study was to elucidate which isoform of NOS is responsible in rats. Immunohistochemistry showed that inducible NOS (iNOS) was constitutively expressed in...

journal_title：Digestive diseases and sciences

authors： Holm M,Powell T,Casselbrant A,Johansson B,Fändriks L

更新日期：2001-08-01 00:00:00

abstract：:Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

journal_title：Digestive diseases and sciences

authors： Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

更新日期：2017-12-01 00:00:00

abstract：:The treatment options for palliating malignant gastroduodenal obstruction include open gastrojejunostomy (OGJ), laparoscopic gastrojejunostomy (LGJ), and endoscopic stenting (ES). The aim of this study was to compare the clinical outcomes and costs among ES, OGJ, and LGJ in patients who present with gastroduodenal obs...

journal_title：Digestive diseases and sciences

authors： Siddiqui A,Spechler SJ,Huerta S

更新日期：2007-01-01 00:00:00

abstract：:Hyperglycemia slows gastric emptying and increases the intensity of perception of gastric distension during fasting and small intestinal nutrient stimulation. In order to examine the possibility that abnormalities of gastric electrical rhythm may be associated with the effects of hyperglycemia, the gastric electrical ...

journal_title：Digestive diseases and sciences

authors： Hebbard GS,Samson M,Andrews JM,Carman D,Tansell B,Sun WM,Dent J,Horowitz M

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Dextran sodium sulphate (DSS) is commonly used to induce intestinal inflammation in rodents. Despite its continuing importance as a model system for examining IBD pathogenesis, the mucosal and systemic immune responses have not been comprehensively documented. AIMS:The purpose of this study was to dissect f...

journal_title：Digestive diseases and sciences

authors： Hall LJ,Faivre E,Quinlan A,Shanahan F,Nally K,Melgar S

更新日期：2011-01-01 00:00:00

abstract：:The effect of chemical deafferentation, vagotomy (VGX), and gangliosympathectomy (GSX) on the density of fibers containing calcitonin gene-related peptide (CGRP) and substance P (Sub.P) in the rat gastric wall was studied. Chemical deafferentation by capsaicin abolished the density of CGRP-immunoreactive (IR) fibers, ...

journal_title：Digestive diseases and sciences

authors： Suzuki T,Kagoshima M,Shibata M,Inaba N,Onodera S,Yamaura T,Shimada H

更新日期：1997-06-01 00:00:00

abstract：:NSAID use and Helicobacter pylori both cause damage to the gastric mucosa and can cause peptic ulcers. Our aim was to test the relationship between gastric mucosal polymorphonuclear leukocyte (PMN) infiltration and the severity of NSAID-induced gastric injury. H. pylori density, mucosal interleukin-8 (IL-8), and nitri...

journal_title：Digestive diseases and sciences

authors： Shiotani A,Yamaoka Y,El-Zimaity HM,Saeed MA,Qureshi WA,Graham DY

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Total parenteral nutrition (TPN), a necessary treatment for patients who cannot receive enteral nutrition, is associated with infectious complications due in part to a loss of intestinal epithelial barrier function (EBF). Using a mouse model of TPN, with enteral nutrient deprivation, we previously demonstrat...

journal_title：Digestive diseases and sciences

authors： Demehri FR,Krug SM,Feng Y,Lee IF,Schulzke JD,Teitelbaum DH

更新日期：2016-06-01 00:00:00

abstract：:A 24-year-old white woman presented with abdominal discomfort associated with a firm, nonpulsatile hepatic mass. Radiological examination, which included radionuclide liver scan, abdominal ultrasonography, computed tomography, and hepatic angiography, demonstrated a large, globular, multilocular cyst arising from the ...

journal_title：Digestive diseases and sciences

authors： Marcial MA,Hauser SC,Cibas ES,Braver J

更新日期：1986-08-01 00:00:00

abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...

journal_title：Digestive diseases and sciences

authors： Sandler RS,Johnson MD,Holland KL

更新日期：1984-08-01 00:00:00

abstract：:Multiple endoscopic biopsies were taken from 100 consecutive patients who had a macroscopically normal colon at colonoscopy. Of these, 78 were regarded as histologically normal; 13 cases of melanosis coli, 7 cases of intestinal spirochetosis, and 2 cases of collagenous colitis were identified. In no cases was there hi...

journal_title：Digestive diseases and sciences

authors： Prior A,Lessells AM,Whorwell PJ

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Autofluorescence imaging (AFI), which is a "red flag" technique during Barrett's surveillance, is associated with significant false positive results. The aim of this study was to assess the inter-observer agreement (IOA) in identifying AFI-positive lesions and to assess the overall accuracy of AFI. METHODS:...

journal_title：Digestive diseases and sciences

authors： Mannath J,Subramanian V,Telakis E,Lau K,Ramappa V,Wireko M,Kaye PV,Ragunath K

更新日期：2013-02-01 00:00:00

abstract：:We examined the preventive effect of metoclopramide on the development of esophageal varices in a rat model. Thirty rats were divided into three groups: metoclopramide (7.5 mg/kg twice a day, intraperitoneally), control group I (saline 2 ml/kg twice a day, intraperitoneally), and control group II (incised lower esopha...

journal_title：Digestive diseases and sciences

authors： Ohta M,Hashizume M,Tanoue K,Ueno K,Komori K,Ishii T,Kitano S,Sugimachi K

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the potential for pancreatic calcification in autoimmune pancreatitis by investigating osteopontin and CD44 expression. METHODS:Human pancreatic tissues in normal pancreas, chronic pancreatitis, and autoimmune pancreatitis were obtained from the surgical specime...

journal_title：Digestive diseases and sciences

authors： Takada H,Nakazawa T,Ohara H,Ando T,Hayashi K,Naito I,Okumura F,Tanaka H,Yamada T,Takahashi S,Joh T

更新日期：2009-04-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：:Endoscopic photodynamic therapy with hematoporphyrin derivative was used in the primary treatment of 54 patients with inoperable gastrointestinal neoplasms. Patients were divided into three groups including 24 with esophageal squamous cell carcinoma, 14 with adenocarcinoma of the stomach or lower third of the esophagu...

journal_title：Digestive diseases and sciences

authors： Patrice T,Foultier MT,Yactayo S,Adam F,Galmiche JP,Douet MC,Le Bodic L

更新日期：1990-05-01 00:00:00

abstract：:A case of hypereosinophilic syndrome with eosinophilic colitis, eosinophilic cholecystitis, and increased serum levels of interleukin-5 (IL-5) and soluble interleukin-2 receptor (sIL-2R) is reported. Immunohistochemical studies of cholecystectomy and colon biopsy specimens with monoclonal antibodies, which are specifi...

journal_title：Digestive diseases and sciences

authors： Tajima K,Katagiri T

更新日期：1996-02-01 00:00:00