Further steps of hepatic stimulatory substance purification.

abstract：:Infection with Helicobacter increases the transcellular passage of macromolecules across the epithelium, and this effect can be prevented by a gastroprotective agent rebamipide. The aim was to gain insight into the mechanisms involved. The HT29-19A intestinal epithelial cells grown on microporous filters as monolayers...

journal_title：Digestive diseases and sciences

authors： Matysiak-Budnik T,Thomas-Collignon A,Mégraud F,Heyman M

更新日期：2001-07-01 00:00:00

abstract：:The effect of inhibition of acid secretion on parietal cell morphology and the concentration of H,K-ATPase alpha-subunit protein was determined by electron microscopy and western blotting. Omeprazole or famotidine alone or in combination were used. Control animals showed a morphological stimulation index (0 = resting,...

journal_title：Digestive diseases and sciences

authors： Scott DR,Besancon M,Sachs G,Helander H

更新日期：1994-10-01 00:00:00

abstract：:Cyclin D1 plays an important role in the multi-step process of gastrointestinal tumorigenesis. We hypothesize that normal enterocytes over-expressing cyclin D1 will demonstrate a transformed phenotype. The nontumorigenic intestinal epithelial cell line, IEC-18, was transfected with the vector pMV7-CCND1, encoding cycl...

journal_title：Digestive diseases and sciences

authors： Kazanov D,Shapira I,Pick M,Kolker O,Liberman E,Deutsch V,Strier L,Dvory-Sobol H,Kunik T,Arber N

更新日期：2003-07-01 00:00:00

abstract：:Capsaicin-sensitive afferent nerves (CSANs) are involved in the protection of gastric mucosa. To clarify the role of CSANs in human Helicobacter pylori-negative or -positive chronic gastritis, after bacterium detection by rapid urease test, (14)C urea breath test, and specific histological staining, the immunodistribu...

journal_title：Digestive diseases and sciences

authors： Dömötör A,Kereskay L,Szekeres G,Hunyady B,Szolcsányi J,Mózsik G

更新日期：2007-02-01 00:00:00

abstract：:The aim of this study was to compare the effect on HCV RNA levels of using induction dosing with 5 MU interferon-alpha2b (IFN) given daily for four weeks followed by 5 MU IFN given three times a week (TIW) for 44 weeks vs standard noninduction TIW dosing of 5 MU IFN for 48 weeks. We randomly assigned 135 patients with...

journal_title：Digestive diseases and sciences

authors： Gonzalez HJ,Ho SB,Gross JB,Peine C,McKee D,Smith T,Midwest Hepatitis Study Group.

更新日期：2002-04-01 00:00:00

abstract：:A primary histiocytic lymphoma arising in the esophagus and its resultant spontaneous perforation is reported in a 69-year-old female. To our knowledge esophageal perforation occurring as a complication of a primary non-Hodgkin's lymphoma of the esophagus has not been previously reported. ...

journal_title：Digestive diseases and sciences

authors： Kirsch HL,Cronin DW,Stein GN,Latour F,Herrera AF

更新日期：1983-04-01 00:00:00

abstract：:The purpose of this study is to determine the long-term relapse rate and associated risk factors in HBeAg-positive chronic hepatitis B (CHB) patients who had maintained virologic response (VR) for 1 year after lamivudine (LMV) discontinuation. We enrolled 55 treatment-naive HBeAg-positive CHB patients who achieved and...

journal_title：Digestive diseases and sciences

authors： Kim JH,Lee SJ,Joo MK,Kim CH,Choi JH,Jung YK,Yim HJ,Yeon JE,Park JJ,Kim JS,Bak YT,Byun KS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:miR-30a expression is down-regulated and regulates tumor suppressors in various cancers. AIM:We investigated the mechanisms underlying the biological role of miR-30a in CRC. METHODS:MicroRNA, mRNA, and protein expression were analyzed by quantitative real-time PCR and Western blot. The migration and invasi...

journal_title：Digestive diseases and sciences

authors： Liu YC,Park YR,Kim SL,Lee ST,Kim SW

更新日期：2017-11-01 00:00:00

abstract：:Gastroenterologists are in a unique position to assist women with chronic gastrointestinal disorders in order to optimize their health prior to pregnancy. Women, whether with chronic conditions or not, and their infants are more likely to be healthy when pregnancies are planned. Achieving a planned pregnancy at the id...

journal_title：Digestive diseases and sciences

authors： Sridhar A,Cwiak CA,Kaunitz AM,Allen RH

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to assess resting energy expenditure in patients with chronic pancreatitis; 33 patients with alcohol-related chronic pancreatitis (group 1: 13 normal weight, group 2: 20 underweight) and 11 undernourished patients without identifiable disease (group 3) were studied. Body composition was deter...

journal_title：Digestive diseases and sciences

authors： Hébuterne X,Hastier P,Péroux JL,Zeboudj N,Delmont JP,Rampal P

更新日期：1996-03-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00

abstract：:The study aimed to examine the serum serological response among H. pylori-infected patients with various upper gastrointestinal diagnoses; to ascertain whether it could be predictive to the diagnostic outcome of dyspepsia. One hundred seventy H. pylori-infected patients with dyspeptic symptoms but without previous tre...

journal_title：Digestive diseases and sciences

authors： Shiesh SC,Sheu BS,Yang HB,Tsao HJ,Lin XZ

更新日期：2000-04-01 00:00:00

abstract：:Intraoperative radiation therapy has been introduced to improve survival rates after resection of biliopancreatic cancer. Early and late effects of intraoperative radiation on the exocrine and endocrine functions of the residual pancreas were examined in 54 patients with pancreatic head resection. Of the 54 patients, ...

journal_title：Digestive diseases and sciences

authors： Yamaguchi K,Nakamura K,Kimura M,Yokohata K,Noshiro H,Chijiiwa K,Tanaka M

更新日期：2000-06-01 00:00:00

abstract：:Fructose and lactose malabsorption are characterized by impaired duodenal fructose transport or by the deficiency of mucosal lactase, respectively. As a consequence, the nonabsorbed saccharides reach the colon, where they are broken down by bacteria to short fatty acids, CO2, and H2. Bloating, cramps, osmotic diarrhea...

journal_title：Digestive diseases and sciences

authors： Ledochowski M,Widner B,Sperner-Unterweger B,Propst T,Vogel W,Fuchs D

更新日期：2000-07-01 00:00:00

abstract：:Pharmacological agents that might influence the poststimulus rebound contractile response (PSRR) through an action on the intrinsic inhibitory innervation of the circular muscle coat were studied in the large intestine of the piebald mouse model for Hirschsprung's disease. Tetrodotoxin (0.3-3 microM) suppressed, in a ...

journal_title：Digestive diseases and sciences

authors： Wood JD,Brann LR

更新日期：1986-07-01 00:00:00

abstract：:Esophageal diverticula can cause significant symptoms and affect the quality of life. There has been recent interest in the use of peroral endoscopic myotomy in the management of esophageal diverticula (D-POEM). In this meta-analysis, we have evaluated the efficacy and safety of D-POEM in the management of esophageal ...

journal_title：Digestive diseases and sciences

authors： Kamal F,Khan MA,Lee-Smith W,Sharma S,Marella HK,Iqbal U,Mcdonough S,Aslam A,Ismail MK,Tombazzi C,Adler DG

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND AND AIM:To explore the CT signs which permit estimation of clinically severe portal hypertension (PH) [≥ 12 of hepatic vein pressure gradient (HVPG)]. METHODS:One-hundred and seven consecutive patients who underwent HVPG measurement in the PH group and 52 controls were included. The diameters of main portal...

journal_title：Digestive diseases and sciences

authors： Lee JY,Kim TY,Jeong WK,Kim Y,Kim J,Kim KW,Kim YH,Sohn JH

更新日期：2014-09-01 00:00:00

abstract：:Chronic abdominal wall pain (CAWP) is common and frequently mistaken for visceral pain. We determined the stability of this diagnosis with Main Outcome Measures of: (a) change of pain intensity after local anesthetic-corticosteroid injection, (b) pain relief after three or more months follow-up, and (c) costs of diagn...

journal_title：Digestive diseases and sciences

authors： Greenbaum DS,Greenbaum RB,Joseph JG,Natale JE

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that Foxp3+ regulatory T (Treg) cells act as inhibitory mediators of inflammation; however, the in vivo mechanism underlying this protection remains elusive in liver diseases. AIMS:To clarify the in vivo role of Foxp3+ Treg cells in liver fibrosis, we used the DEREG mouse, whi...

journal_title：Digestive diseases and sciences

authors： Roh YS,Park S,Lim CW,Kim B

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Defective autophagic machinery, such as that in Crohn's disease patients homozygous for ATG16L1 risk allele, is associated with alteration of resident gut bacterial communities. However, whether or not host autophagy responds to changes in the resident gut microbial community is not known. Here, we investiga...

journal_title：Digestive diseases and sciences

authors： Singh SB,Wilson M,Ritz N,Lin HC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:SEL1L gene product is implicated in the endoplasmic reticulum (ER)-associated protein degradation and Unfolded Protein Response pathways. This gene and associated miRNAs have been indicated as predictive and prognostic markers of pancreatic cancer. AIM:Explore the role of SEL1L in colorectal cancer (CRC) pr...

journal_title：Digestive diseases and sciences

authors： Ashktorab H,Green W,Finzi G,Sessa F,Nouraie M,Lee EL,Morgano A,Moschetta A,Cattaneo M,Mariani-Costantini R,Brim H,Biunno I

更新日期：2012-04-01 00:00:00

abstract：:The objective of this study was to investigate the effects of types of dialysis treatments on hepatitis C virus infection and the epidemiologic properties of hepatitis C virus (HCV) infection at three Baskent University hospitals, in Ankara, Adana, and Izmir, Turkey, in 655, 326, and 118 patients with end-stage renal ...

journal_title：Digestive diseases and sciences

authors： Selcuk H,Kanbay M,Korkmaz M,Gur G,Akcay A,Arslan H,Ozdemir N,Yilmaz U,Boyacioglu S

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and diabetes are risk factors for advanced alcoholic liver disease, and both are components of the metabolic syndrome. We aimed to assess the prevalence of metabolic syndrome and its components in a contemporary US cohort of adults with alcoholic liver disease and compare it to a historic co...

journal_title：Digestive diseases and sciences

authors： Singh A,Amin H,Garg R,Gupta M,Lopez R,Alkhouri N,MCCullough A

更新日期：2020-11-01 00:00:00

abstract：:Dieulafoy's lesion or cirsoid aneurysm is a rare cause of massive upper gastrointestinal hemorrhage. Historically cirsoid aneurysm most often occurs in the stomach, but has been reported to occur in the jejunum. In this paper, four cases are presented that are felt to represent the first documented cases of cirsoid an...

journal_title：Digestive diseases and sciences

authors： McClave SA,Goldschmid S,Cunningham JT,Boyd WP Jr

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori vacuolating cytotoxin, VacA, stimulates apoptosis via a mitochondria-dependent pathway. VacA induces apoptosis via activation of the pro-apoptotic B-cell lymphoma (Bcl)-2 family proteins, Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak), while the implication ...

journal_title：Digestive diseases and sciences

authors： Matsumoto A,Isomoto H,Nakayama M,Hisatsune J,Nishi Y,Nakashima Y,Matsushima K,Kurazono H,Nakao K,Hirayama T,Kohno S

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Stent placement in the distal duodenum can be difficult. We describe a case report of a 94-year-old man with metastatic pancreatic head cancer compressing the third and fourth portions of the duodenum, treated by endoscopic stent placement using a colonoscope. AREAS COVERED:A literature review highlighted...

journal_title：Digestive diseases and sciences

authors： Minervini A,Lauro A,Pagano N,Vaccari S,D'Andrea V,Marino IR,Cervellera M,Tonini V

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Autofluorescence imaging (AFI), which is a "red flag" technique during Barrett's surveillance, is associated with significant false positive results. The aim of this study was to assess the inter-observer agreement (IOA) in identifying AFI-positive lesions and to assess the overall accuracy of AFI. METHODS:...

journal_title：Digestive diseases and sciences

authors： Mannath J,Subramanian V,Telakis E,Lau K,Ramappa V,Wireko M,Kaye PV,Ragunath K

更新日期：2013-02-01 00:00:00

abstract：:Our purpose is to describe seven cases of disseminated aseptic abscesses with regard to clinical, biological, radiological, and histological information, treatment, and outcome. Data were collected on seven Caucasian patients who had proven sterile deep abscesses diagnosed in French university hospitals. The onset of ...

journal_title：Digestive diseases and sciences

authors： André M,Aumaître O,Papo T,Kemeny JL,Vital-Durand D,Rousset H,Ninet J,Pointud P,Charlotte F,Godeau B,Schmidt J,Marcheix JC,Piette JC

更新日期：1998-02-01 00:00:00

abstract：:Longitudinal shortening of the esophagus during peristaltic contraction has been previously analyzed globally using spaced mucosal clips. This method gives a relatively crude measurement. In this study, local longitudinal shortening (LLS) was evaluated using simultaneous high-resolution endoluminal ultrasound (HREUS) ...

journal_title：Digestive diseases and sciences

authors： Dai Q,Korimilli A,Thangada VK,Chung CY,Parkman H,Brasseur J,Miller LS

更新日期：2006-01-01 00:00:00

abstract：:Upper gastrointestinal endoscopy was performed for the evaluation of infectious esophagitis in 19 consecutive subjects evaluated prospectively before orthotopic liver transplantation (OLTx), in a separate group of 27 subjects post-OLTx, and in 21 subjects following orthotopic renal transplantation (ORTx). None of the ...

journal_title：Digestive diseases and sciences

authors： Alexander JA,Brouillette DE,Chien MC,Yoo YK,Tarter RE,Gavaler JS,Van Thiel DH

更新日期：1988-09-01 00:00:00