Abstract：
:Capsaicin-sensitive afferent nerves (CSANs) are involved in the protection of gastric mucosa. To clarify the role of CSANs in human Helicobacter pylori-negative or -positive chronic gastritis, after bacterium detection by rapid urease test, (14)C urea breath test, and specific histological staining, the immunodistribution of capsaicin receptor, calcitonin gene-related peptide (CGRP), and substance P (SP) was studied in 21 H. pylori-positive and 30 H. pylori-negative patients with chronic gastritis and 20 patients with functional dyspepsia (as histologically healthy controls). The expression of capsaicin receptor, CGRP, and SP was significantly higher in the mucosa of patients with chronic gastritis than in controls, however, no significant difference was obtained in the immunodistribution in patients with H. pylori-negative versus H. pylori-positive gastritis. In conclusion, CSANs participate in the development of human gastritis, however, their participation does not depend on the presence of Helicobacter pylori as a causative factor.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Dömötör A,Kereskay L,Szekeres G,Hunyady B,Szolcsányi J,Mózsik Gdoi
10.1007/s10620-006-9180-7subject
Has Abstractpub_date
2007-02-01 00:00:00pages
411-7issue
2eissn
0163-2116issn
1573-2568journal_volume
52pub_type
杂志文章abstract：:Four patients with cold urticaria and six control subjects were studied. Gastric acid output was measured for 1 hr before and 1 hr after the immersion of both hands in ice cold water. The mean acid output fell in the control group by 16.3%. Acid output in the cold urticaria patients rose in each case following the col...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01315214
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Digestive diseases and sciences
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更新日期：2009-02-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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更新日期：1979-05-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01540400
更新日期：1990-05-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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更新日期：2013-06-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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abstract：BACKGROUND AND AIMS:The dose recommendation for entecavir (ETV) is 0.5 mg daily for treatment-naïve chronic hepatitis B (CHB) patients and 1.0 mg daily for lamivudine-refractory patients; however, few data are available for the efficacy of a 1.0-mg daily dose in treatment-naïve CHB patients. Our goal is to examine the ...
journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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更新日期：1989-06-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 已发布勘误
doi：10.1007/s10620-020-06524-8
更新日期：2020-08-08 00:00:00
