Is biopsy necessary if colonoscopy is normal?

abstract：BACKGROUND:The NIH-sponsored Patient-Reported Outcomes Measurement Information System (PROMIS) Gastrointestinal (GI) Symptoms scales were developed to assess patients' GI symptoms in clinical settings. AIMS:To assess responsiveness to change and provide minimally important difference (MID) estimates for the PROMIS GI ...

journal_title：Digestive diseases and sciences

authors： Khanna D,Hays RD,Shreiner AB,Melmed GY,Chang L,Khanna PP,Bolus R,Whitman C,Paz SH,Hays T,Reise SP,Spiegel B

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:This study focused on unhealed gastrocutaneous fistulas to resolve whether standard drugs that promote healing of gastric ulcers may simultaneously have the same effect on cutaneous wounds, and corticosteroid aggravation, and to demonstrate why peptides such as BPC 157 exhibit a greater healing effect. Theref...

journal_title：Digestive diseases and sciences

authors： Skorjanec S,Dolovski Z,Kocman I,Brcic L,Blagaic Boban A,Batelja L,Coric M,Sever M,Klicek R,Berkopic L,Radic B,Drmic D,Kolenc D,Ilic S,Cesarec V,Tonkic A,Zoricic I,Mise S,Staresinic M,Ivica M,Lovric Bencic M,Anic

更新日期：2009-01-01 00:00:00

abstract：:Hepatic steatosis is a recognized feature of hepatitis C viral infection, particularly in genotype 3. The demographics and the associations contributing to moderate to severe steatosis in genotype 3 are not very well studied. The aim of this study is to determine the demographics and association of steatosis with fibr...

journal_title：Digestive diseases and sciences

authors： Sharma P,Balan V,Hernandez J,Rosati M,Williams J,Rodriguez-Luna H,Schwartz J,Harrison E,Anderson M,Byrne T,Vargas HE,Douglas DD,Rakela J

更新日期：2004-01-01 00:00:00

abstract：:To evaluate the frequency and type of gastroduodenal mucosal inflammatory changes in patients with symptomatic acid peptic disease and nonulcer dyspepsia, 100 patients with gastrointestinal symptoms indicative of acid peptic disease or dyspepsia and 10 control subjects were clinically evaluated and underwent radiograp...

journal_title：Digestive diseases and sciences

authors： Greenlaw R,Sheahan DG,DeLuca V,Miller D,Myerson D,Myerson P

更新日期：1980-09-01 00:00:00

abstract：:This study was conducted to determine the ion transport mechanisms in the normal mouse cecum and compare them to an inbred mouse model of colitis. The Ussing chamber-voltage clamp technique was used to monitor the short circuit current (I(sc)). The basal I(sc) in the normal cecum was 82.6 +/- 5.8 microA/cm2. It was no...

journal_title：Digestive diseases and sciences

authors： Homaidan FR,Tripodi J,Cheng P,Donovan V,Burakoff R

更新日期：1999-08-01 00:00:00

abstract：:The significance of hyperplastic polyps of the gastric antrum in anemic patients with suspected gastrointestinal bleeding has not been determined. The aim of this study is to evaluate the prevalence and prognosis of such polyps in this patient group. Clinical records of patients referred to our endoscopy lab from Nove...

journal_title：Digestive diseases and sciences

authors： Al-Haddad M,Ward EM,Bouras EP,Raimondo M

更新日期：2007-01-01 00:00:00

abstract：:Calcineurin inhibitor (CI)-associated renal dysfunction has emerged as a major cause of morbidity and mortality after liver transplantation. In this retrospective study, we compared the efficacy, safety, and renal protective effect of sirolimus monotherapy (Group A; n = 26) with sirolimus in combination (Group B; n = ...

journal_title：Digestive diseases and sciences

authors： Maheshwari A,Torbenson MS,Thuluvath PJ

更新日期：2006-10-01 00:00:00

abstract：:Magnifying videoendoscopic observation of a minute lesion with a single IIIL type cryptal orifice was reported. This minute lesion was a single-gland adenoma accompanied histopathologically by a bud of adenomatous gland and was located in the upper part of the mucosa. This finding regarding a pit pattern should make p...

journal_title：Digestive diseases and sciences

authors： Tamura S,Nakajo K,Kitamura M,Kamiji I,Onishi S

更新日期：2002-10-01 00:00:00

abstract：:Fractional systemic bioavailability of orally administered drugs was found to be unexpectedly low in liver cirrhosis, even after surgical portal-systemic shunting. Fecal loss or intestinal first-pass elimination were assumed to explain the finding. In this paper we evaluated alternative pathophysiological interpretati...

journal_title：Digestive diseases and sciences

authors： Molino G,Avagnina P,Garrone C,Sansoè G,Degerfeld MM,Peretti P,Tinivella M,Bianco S

更新日期：2001-03-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

journal_title：Digestive diseases and sciences

authors： Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

更新日期：2008-01-01 00:00:00

abstract：:Probiotic bacteria exhibit a variety of properties, which are unique to a particular strain. Lactobacillus acidophilus-SDC 2012, 2013 are new strains isolated from Korean infants' feces. The potential utility of Lactobacillus acidophilus-SDC 2012, 2013 in irritable bowel syndrome (IBS) was studied. Forty IBS patients ...

journal_title：Digestive diseases and sciences

authors： Sinn DH,Song JH,Kim HJ,Lee JH,Son HJ,Chang DK,Kim YH,Kim JJ,Rhee JC,Rhee PL

更新日期：2008-10-01 00:00:00

abstract：:Somatostatin analog SMS 201-995 causes a dose-related suppression of the release and/or action of several gastrointestinal hormones and impairs several anterior pituitary functions. Some patients with illness involving abnormal hormonal activity have responded to treatment with SMS 201-995, including resolution of sev...

journal_title：Digestive diseases and sciences

authors： Greenberg RN

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

journal_title：Digestive diseases and sciences

authors： Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

更新日期：2014-06-01 00:00:00

abstract：:We report a case of localized jejunal amyloidosis occurring in a 74-year-old man who experienced an episode of digestive bleeding while he was receiving oral anticoagulation. It illustrates a rare entity, characterized by an endoscopic aspect of polypoid, pseudotumoral formations. Histologically, submucosal connective...

journal_title：Digestive diseases and sciences

authors： Peny MO,Debongnie JC,Haot J,Van Gossum A

更新日期：2000-09-01 00:00:00

abstract：:We report four patients with pneumothorax as a complication of ERCP with sphincterotomy. With conservative treatment all patients recovered. Previously, 16 comparable cases have been reported in the literature. The main risk factor for this rare complication seems (pre-cut) sphincterotomy. Pneumothorax is usually righ...

journal_title：Digestive diseases and sciences

authors： Schepers NJ,van Buuren HR

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Periampullary diverticulum (PAD) is most often asymptomatically found in elderly population. ERCP in the presence of PAD is technically challenging since the location and orientation of the ampulla could be altered. Various studies have reported differing results on the technical success and safety outcome...

journal_title：Digestive diseases and sciences

authors： Jayaraj M,Mohan BP,Dhindsa BS,Mashiana HS,Radhakrishnan G,Dhir V,Trindade AJ,Adler DG

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Intrasphincteric injection of botulinum toxin (BTX) and removable self-expanding metal stents (SEMS) have both been used for the treatment of achalasia. AIM:To compare the effectiveness and long-term outcome of SEMS placement and BTX injection in patients with achalasia. METHODS:A total of 110 patients wit...

journal_title：Digestive diseases and sciences

authors： Cai XB,Dai YM,Wan XJ,Zeng Y,Liu F,Wang D,Zhou H

更新日期：2013-07-01 00:00:00

abstract：:In a subset of patients with gastroesophageal reflux disease (GERD), symptoms persist in spite of proton pump inhibitor (PPI) therapy. Endoscopic gastroplication (EG) was reported to provide a novel therapeutic option in GERD. To evaluate symptomatic and objective outcome of EG in PPI refractory GERD, consecutive GERD...

journal_title：Digestive diseases and sciences

authors： Arts J,Lerut T,Rutgeerts P,Sifrim D,Janssens J,Tack J

更新日期：2005-02-01 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant connective tissue disease caused by mutations in the type III collagen gene resulting in extreme tissue fragility. Affected individuals are at risk of dramatic and often fatal complications, mostly spontaneous arterial, uterine, or colonic ruptures. Phenoty...

journal_title：Digestive diseases and sciences

authors： Gelbmann CM,Köllinger M,Gmeinwieser J,Leser HG,Holstege A,Schölmerich J

更新日期：1997-08-01 00:00:00

abstract：:To study the clinicopathologic features of hepatitis C viremic patients negative for hepatitis C antibodies (anti-HCV) by current second-generation assay, we categorized 139 consecutive histologically verified patients with chronic non-A, non-B hepatitis into three groups: 121 (87%) were positive for second-generation...

journal_title：Digestive diseases and sciences

authors： Kao JH,Lai MY,Hwang YT,Yang PM,Chen PJ,Sheu JC,Wang TH,Hsu HC,Chen DS

更新日期：1996-01-01 00:00:00

abstract：:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, s...

journal_title：Digestive diseases and sciences

authors： Campieri M,Gionchetti P,Belluzzi A,Brignola C,Migaldi M,Tabanelli GM,Bazzocchi G,Miglioli M,Barbara L

更新日期：1987-12-01 00:00:00

abstract：:We examined the effect of cyclooxygenase (COX) inhibitors on dextran sulfate sodium (DSS)-induced ulcerative colitis in rats and investigated the role of COX isozymes in the pathogenesis of this model. Experimental colitis was induced by treatment with 2.5% DSS in drinking water for 6 days. Indomethacin (a nonselectiv...

journal_title：Digestive diseases and sciences

authors： Okayama M,Hayashi S,Aoi Y,Nishio H,Kato S,Takeuchi K

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND AIM:Diabetes is the main cause of gastroparesis accompanying decreased neuronal nitric oxide synthase (nNOS) in myenteric ganglia of the stomach. Decreased nNOS expression in the stomach also results from defects in apolipoprotein E (ApoE), which is secreted by astrocytes and has neuroprotective effects ...

journal_title：Digestive diseases and sciences

authors： Fukuhara S,Masaoka T,Nishimura S,Nakamura M,Matsuzaki J,Tsugawa H,Miyoshi S,Mori H,Kawase S,Shibata S,Okano H,Kanai T,Suzuki H

更新日期：2017-12-01 00:00:00

abstract：:Tacrolimus, a relatively new therapeutic option for patients with corticosteroid-refractory Crohn's disease or ulcerative colitis, is a substrate for the apically directed efflux transporter P-glycoprotein (P-gp). Duodenal biopsy specimens obtained from a patient with corticosteroid-refractory Crohn's disease and with...

journal_title：Digestive diseases and sciences

authors： Buchman AL,Paine MF,Wallin A,Ludington SS

更新日期：2005-12-01 00:00:00

abstract：:Glucagon-like peptide-2 (GLP-2) is an enteroendocrine hormone which is uniquely trophic for the intestine; a physiological role in regulating nutrient absorptive capacity is becoming apparent. GLP-2, independent of enteral feeding, stimulates a classical pattern of intestinal adaptation in terminal ileum following res...

journal_title：Digestive diseases and sciences

authors： Sigalet DL,Bawazir O,Martin GR,Wallace LE,Zaharko G,Miller A,Zubaidi A

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The Chronic Hepatitis Cohort Study (CHeCS) is a longitudinal observational study of risks and benefits of treatments and care in patients with chronic hepatitis B (HBV) and C (HCV) infection from four US health systems. We hypothesized that comparative effectiveness methods-including a centralized d...

journal_title：Digestive diseases and sciences

authors： Lu M,Rupp LB,Moorman AC,Li J,Zhang T,Lamerato LE,Holmberg SD,Spradling PR,Teshale EH,Vijayadeva V,Boscarino JA,Schmidt MA,Nerenz DR,Gordon SC

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Esophageal epithelial microRNAs may be used to diagnose Barrett's esophagus (BE) and possibly monitor its progression to esophageal adenocarcinoma (EAC). AIMS:We reviewed studies that have investigated this to identify microRNAs with high biomarker potential for screening and disease monitoring in BE. METH...

journal_title：Digestive diseases and sciences

authors： Mallick R,Patnaik SK,Wani S,Bansal A

更新日期：2016-04-01 00:00:00

abstract：:Lichen planus is a common mucocutaneus disorder that rarely involves the esophagus. We report two challenging cases presenting with recurrent dysphagia originally suspected due to gastroesophageal reflux. Subsequent evaluation revealed peculiar endoscopic findings of desquamative esophagitis leading to the diagnosis o...

journal_title：Digestive diseases and sciences

authors： Ukleja A,DeVault KR,Stark ME,Achem SR

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:The majority of ghrelin producing cells (GPC) are present in the fundic gland of the stomach and recognized as X/A like cells. The detailed distribution of GPC in the stomach is still unknown in healthy and pathological subjects. METHODS:We investigated the detailed distribution of GPC in the stomach, especi...

journal_title：Digestive diseases and sciences

authors： Takiguchi S,Adachi S,Yamamoto K,Morii E,Miyata H,Nakajima K,Yamasaki M,Kangawa K,Mori M,Doki Y

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Industrialization has been linked to the etiology of inflammatory bowel disease (IBD). AIM:We investigated the association between air pollution exposure and IBD. METHODS:The European Prospective Investigation into Cancer and Nutrition cohort was used to identify cases with Crohn's disease (CD) (n = 38) an...

journal_title：Digestive diseases and sciences

authors： Opstelten JL,Beelen RMJ,Leenders M,Hoek G,Brunekreef B,van Schaik FDM,Siersema PD,Eriksen KT,Raaschou-Nielsen O,Tjønneland A,Overvad K,Boutron-Ruault MC,Carbonnel F,de Hoogh K,Key TJ,Luben R,Chan SSM,Hart AR,Bueno-de-

更新日期：2016-10-01 00:00:00