Abstract:
:Probiotic bacteria exhibit a variety of properties, which are unique to a particular strain. Lactobacillus acidophilus-SDC 2012, 2013 are new strains isolated from Korean infants' feces. The potential utility of Lactobacillus acidophilus-SDC 2012, 2013 in irritable bowel syndrome (IBS) was studied. Forty IBS patients were randomized into a placebo (n = 20) and probiotics group (n = 20). Four weeks of treatment with L. acidophilus-SDC 2012, 2013 was associated with a reduced score for abdominal pain or discomfort compared to the baseline (P = 0.011). The percent reduction in abdominal pain or discomfort exceeded the placebo scores by more than 20% (23.8 and 0.2% for probiotics and placebo, respectively, P = 0.003). There was a significant difference in the proportion of responders between the probiotics and placebo groups (P = 0.011). There was no drop out or adverse events for either group during the study period. Lactobacillus acidophilus-SDC 2012, 2013 appeared to have a beneficial effect in patients with IBS. Further studies are warranted.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Sinn DH,Song JH,Kim HJ,Lee JH,Son HJ,Chang DK,Kim YH,Kim JJ,Rhee JC,Rhee PLdoi
10.1007/s10620-007-0196-4subject
Has Abstractpub_date
2008-10-01 00:00:00pages
2714-8issue
10eissn
0163-2116issn
1573-2568journal_volume
53pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is a common malignancy worldwide with poor outcomes. Therefore, it is important to identify a valuable prognostic biomarker for HCC. The present study aimed to identify novel prognostic biomarkers for HCC and evaluate the potential role of hub genes in HCC. METHODS:Weighted ge...
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