Surface structure of single-gland adenoma in familial adenomatous polyposis.

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is an accepted pathologic precursor to gastric adenocarcinoma (GAC). While surveillance of GIM in Europe and Asia is common, only limited recommendations related to endoscopic surveillance of GIM exist in the United States. AIM:To understand the clinical practice patterns...

journal_title：Digestive diseases and sciences

authors： Vance RB Jr,Kubiliun N,Dunbar KB

更新日期：2016-07-01 00:00:00

abstract：:Misoprostol, a synthetic prostaglandin E1 methyl ester analog with gastric antisecretory and cytoprotective properties, prevents the development of acute experimental gastric and duodenal ulcers in various animal models. This study was designed as a multicenter randomized double-blind parallel-group comparison of the ...

journal_title：Digestive diseases and sciences

authors： Agrawal NM,Saffouri B,Kruss DM,Callison DA,Dajani EZ

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Corticosteroids and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis (SAH), but not to the extent desired. Combining both drugs may lead to better survival, but has not yet been studied. AIM:To compare the efficacy of corticosteroids plus pentoxifylline with that of corticosteroids a...

journal_title：Digestive diseases and sciences

authors： Sidhu SS,Goyal O,Singla P,Gupta D,Sood A,Chhina RS,Soni RK

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary complications (BCs) occur in up to 40% of living donor liver transplant (LDLT) recipients. The aim of this study was to evaluate the efficacy of endoscopic therapy in the management of LDLT-related BCs. METHODS:A retrospective study of 100 LDLT recipients at a single transplant center over ...

journal_title：Digestive diseases and sciences

authors： Elwir S,Thompson J,Amateau SK,Trikudanathan G,Attam R,Hassan M,Kandaswamy R,Pruett T,Lake J,Chinnakotla S,Freeman ML,Arain MA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Lipopolysaccharide binding protein (LBP) is involved in the modulation of acute liver injury and failure caused by acetaminophen (APAP). Although the biological activity of LBP is concentration dependent, little is known about its levels in acute liver failure. METHODS:Serum and hepatic LBP were me...

journal_title：Digestive diseases and sciences

authors： Su GL,Fontana RJ,Jinjuvadia K,Bayliss J,Wang SC

更新日期：2012-04-01 00:00:00

abstract：:The aim of the present study was to investigate the antioxidative effects of water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), on ischemia-reperfusion (I/R) -induced gastric mucosal injury in rats. Gastric ischemia was induced by applying a small clamp to the c...

journal_title：Digestive diseases and sciences

authors： Ichikawa H,Yoshida N,Takano H,Ishikawa T,Handa O,Takagi T,Naito Y,Murase H,Yoshikawa T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is associated with tissue remodeling that can result in esophageal mucosal fragility, and esophageal dilation for patients with EoE is known to cause painful mucosal lacerations. Clinicians have been admonished that patients with EoE may be exceptionally predisposed to perforat...

journal_title：Digestive diseases and sciences

authors： Jacobs JW Jr,Spechler SJ

更新日期：2010-06-01 00:00:00

abstract：:We examined the effect of cyclooxygenase (COX) inhibitors on dextran sulfate sodium (DSS)-induced ulcerative colitis in rats and investigated the role of COX isozymes in the pathogenesis of this model. Experimental colitis was induced by treatment with 2.5% DSS in drinking water for 6 days. Indomethacin (a nonselectiv...

journal_title：Digestive diseases and sciences

authors： Okayama M,Hayashi S,Aoi Y,Nishio H,Kato S,Takeuchi K

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Corticotropin-releasing factor (CRF) peptides exert profound effects on the secretomotor function of the gastrointestinal tract. Nevertheless, despite the presence of CRF peptides and receptors in colonic tissue, their influence on colonic blood flow (CBF) is unknown. AIM:To determine the effect and mechani...

journal_title：Digestive diseases and sciences

authors： Akiba Y,Kaunitz JD,Million M

更新日期：2015-04-01 00:00:00

abstract：:In view of the increased anticoagulant effect of acetaldehyde-treated heparin, other glycosaminoglycans (GAGs) such as chondroitin sulfates A and C, dermatan sulfate (chondroitin sulfate B), heparan sulfate, and hyaluronic acid were tested for anticoagulant activity before and after exposure to acetaldehyde. Clotting ...

journal_title：Digestive diseases and sciences

authors： Brecher AS,Adamu MT

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Although the overall incidence of hepatitis B virus (HBV) has declined since the introduction of universal vaccine guidelines, the incidence remains elevated in high risk groups. Recent guidelines from the Centers for Disease Control (CDC) have underscored the importance of vaccination against HBV in high ri...

journal_title：Digestive diseases and sciences

authors： Foster T,Hon H,Kanwal F,Han S,Spiegel B

更新日期：2011-12-01 00:00:00

abstract：:We studied the natural history of ulcerative colitis (UC) by following 1116 patients in whom UC had been diagnosed or confirmed at The Cleveland Clinic Foundation between 1960 and 1983. Data before 1973 were obtained retrospectively. Criteria for inclusion in the study were: a diagnosis of UC confirmed by clinical, ra...

journal_title：Digestive diseases and sciences

authors： Farmer RG,Easley KA,Rankin GB

更新日期：1993-06-01 00:00:00

abstract：:The purpose of this study was to characterize the diagnostic process, frequency of associated disorders, family history, and impact of a gluten-free diet in individuals with celiac disease. All members of the Canadian Celiac Association (n=5240) were surveyed with a questionnaire. Respondents included 2681 adults with...

journal_title：Digestive diseases and sciences

authors： Cranney A,Zarkadas M,Graham ID,Butzner JD,Rashid M,Warren R,Molloy M,Case S,Burrows V,Switzer C

更新日期：2007-04-01 00:00:00

abstract：:Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

journal_title：Digestive diseases and sciences

authors： Ainley EJ,Winwood PJ,Begley JP

更新日期：2005-07-01 00:00:00

abstract：:The effect of inhibition of acid secretion on parietal cell morphology and the concentration of H,K-ATPase alpha-subunit protein was determined by electron microscopy and western blotting. Omeprazole or famotidine alone or in combination were used. Control animals showed a morphological stimulation index (0 = resting,...

journal_title：Digestive diseases and sciences

authors： Scott DR,Besancon M,Sachs G,Helander H

更新日期：1994-10-01 00:00:00

abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...

journal_title：Digestive diseases and sciences

authors： Heresbach D,Bretagne JF,Raoul JL,Moisan A,Siproudhis L,Devillers A,Gosselin M

更新日期：1993-09-01 00:00:00

abstract：:Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

journal_title：Digestive diseases and sciences

authors： Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

更新日期：1991-12-01 00:00:00

abstract：:The objective of this study was to investigate the effects of types of dialysis treatments on hepatitis C virus infection and the epidemiologic properties of hepatitis C virus (HCV) infection at three Baskent University hospitals, in Ankara, Adana, and Izmir, Turkey, in 655, 326, and 118 patients with end-stage renal ...

journal_title：Digestive diseases and sciences

authors： Selcuk H,Kanbay M,Korkmaz M,Gur G,Akcay A,Arslan H,Ozdemir N,Yilmaz U,Boyacioglu S

更新日期：2006-08-01 00:00:00

abstract：:There is a lack of information about the effect of omeprazole or other antisecretory drugs on intraduodenal pH. Aim of the study was to document the variation over time of intraduodenal pH during a 24-hr period and to simultaneously study the effect of omeprazole 40 mg once daily on intragastric and intraduodenal pH i...

journal_title：Digestive diseases and sciences

authors： Gan KH,Geus WP,Lamers CB,Heijerman HG

更新日期：1997-11-01 00:00:00

abstract：:Zinc is an essential trace element, exerting important antioxidant, anti-inflammatory, and antiapoptotic effects. It affects growth and development and participates in processes such as aging and cancer induction. The liver is important for the regulation of zinc homeostasis, while zinc is necessary for proper liver f...

journal_title：Digestive diseases and sciences

authors： Stamoulis I,Kouraklis G,Theocharis S

更新日期：2007-07-01 00:00:00

abstract：:Possible differences in the abilities of esophageal body and lower esophageal sphincter muscles to utilize substrates to support agonist-induced contractions were studied. Strips of longitudinal, circular, and lower esophageal sphincter muscle from the opossum esophagus were first contracted to approximately 70% of th...

journal_title：Digestive diseases and sciences

authors： Percy WH,Sutherland J,Christensen J

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer can be difficult to diagnose. Fine-needle aspiration (FNA) biopsies may be negative even when malignancy is present. AIMS:To identify endosonographic features predictive of malignancy that will separate patients into high- and low-risk groups, in whom a negative FNA effectively rules out m...

journal_title：Digestive diseases and sciences

authors： Rodriguez S,Faigel D

更新日期：2010-04-01 00:00:00

abstract：:The potential effect of recombinant human interleukin-11 (rhIL-11) on trinitrobenzene sulfonic acid (TNB)-induced colitis was investigated in rats. Intrarectal TNB (40 mg in 0.25 ml 40% ethanol) produced significant ulcerative colitis. The lesions were most severe at three days after TNB instillation, and then decline...

journal_title：Digestive diseases and sciences

authors： Qiu BS,Pfeiffer CJ,Keith JC Jr

更新日期：1996-08-01 00:00:00

abstract：:We observed five cases of unusual extraperitoneal presentation of diverticulitis during an 11 year period. During that time, a total of 263 patients were operated for diverticulitis. Patients 1-4 presented with an inflammatory spread of diverticulitis through the abdominal wall; in patient 5 multiple abscesses were pr...

journal_title：Digestive diseases and sciences

authors： Rothenbuehler JM,Oertli D,Harder F

更新日期：1993-11-01 00:00:00

abstract：:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, s...

journal_title：Digestive diseases and sciences

authors： Campieri M,Gionchetti P,Belluzzi A,Brignola C,Migaldi M,Tabanelli GM,Bazzocchi G,Miglioli M,Barbara L

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Restoring normal fecal flora through intestinal microbiota transplantation (IMT) was successful in curing recurrent Clostridium difficile infection (CDI). However, only a few cases have been reported of IMT being utilized for the treatment of severe or fulminant CDI. AIM:Is IMT a simple and effective treatm...

journal_title：Digestive diseases and sciences

authors： Zainah H,Hassan M,Shiekh-Sroujieh L,Hassan S,Alangaden G,Ramesh M

更新日期：2015-01-01 00:00:00

abstract：:Alterations of small intestinal sensory thresholds and small intestinal dysmotility are associated with functional dyspepsia. Because gastric and duodenal afferents partly project to the same areas, we postulated that patients with functional dyspepsia and H. pylori infection would be characterized by lower duodenal s...

journal_title：Digestive diseases and sciences

authors： Holtmann G,Talley NJ,Goebell H

更新日期：1996-07-01 00:00:00

abstract：:Several techniques have been developed to diagnose Helicobacter pylori infection and two noninvasive methods are available: carbon 13-urea breath test (UBT) and serology. Measurement of IgG serum antibodies by enzyme-linked immunosorbent assay (ELISA) is a reliable and inexpensive method for detection of infection. Th...

journal_title：Digestive diseases and sciences

authors： Menegatti M,Figura N,Farinelli S,Landi F,Acciardi C,Ricci C,Holton J,Gatta L,Crosatti M,Polacci R,Miglioli M,Vaira D

更新日期：2000-08-01 00:00:00

abstract：:In toxic liver injury, proliferation of preexisting hepatocytes helps restore liver mass and function. While loss of liver mass per se stimulates hepatocyte proliferation, exogenous mitogens have a potential role in enhancing liver regeneration. The aim of this study was to characterize the effects of the mitogen, tri...

journal_title：Digestive diseases and sciences

authors： Malik R,Saich R,Rahman T,Hodgson H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Data on alcohol-related HCC are limited. AIMS:Our aim was to describe the incidence, management, and prognosis of alcohol compared to Hepatitis C (HCV)-related HCC at a national level. METHODS:Incident cases of HCC were identified in French healthcare databases between 2009 and 2012 and analyzed retrospect...

journal_title：Digestive diseases and sciences

authors： Costentin CE,Sogni P,Falissard B,Barbare JC,Bendersky N,Farges O,Goutte N

更新日期：2020-01-01 00:00:00