The Canadian Celiac Health Survey.

abstract：BACKGROUND:Irritable bowel syndrome (IBS) pathophysiology has not been fully understood. Abnormalities of serine proteases have been identified in IBS patients. In addition, protease-activated receptors (PAR) activation interferes with several components of the pathogenesis of IBS, so, evaluating the PAR expression in ...

journal_title：Digestive diseases and sciences

authors： Zhao JH,Dong L,Shi HT,Wang ZY,Shi HY,Ding H

更新日期：2012-01-01 00:00:00

abstract：:Free radical damage in reflux esophagitis of rats induced by 24-hr duodenojejunal ligation was studied. Oxygen free radicals were selectively blocked. Groups were: sham operation, reflux, reflux + superoxide dismutase (SOD), catalase, dimethylthiourea, allopurinol, and inactivated SOD or inactivated catalase alone or ...

journal_title：Digestive diseases and sciences

authors： Wetscher GJ,Hinder PR,Bagchi D,Perdikis G,Redmond EJ,Glaser K,Adrian TE,Hinder RA

更新日期：1995-06-01 00:00:00

abstract：:Celiac disease (CD) is an immune-mediated enteropathy triggered by dietary ingestion of gluten in genetically susceptible patients. CD is often diagnosed by a "case-finding" approach of symptomatic patients. In recent times, the diagnostic paradigm has shifted to investigate patients who may be asymptomatic, but are a...

journal_title：Digestive diseases and sciences

authors： Kumral D,Syed S

更新日期：2020-08-01 00:00:00

abstract：:These studies were done to determine the effects of fluoride (F) on the structure and function of the canine gastric mucosa and the possible protective effects of 16,16-dimethyl-prostaglandin E2 (dmPGE2). A portion of the stomach with its vascular supply intact was mounted in a two-compartment chamber, one side of whi...

journal_title：Digestive diseases and sciences

authors： Whitford GM,Pashley DH,Garman RH

更新日期：1997-10-01 00:00:00

abstract：:Anorectal manometry was performed in 40 women, who consulted for functional disorders of the lower gastrointestinal tract and had been sexually abused. Anismus, defined as a rise in anal pressure during straining, was observed in 39 of 40 abused women, but in only six of 20 healthy control women (P < 0.0001). Other pa...

journal_title：Digestive diseases and sciences

authors： Leroi AM,Berkelmans I,Denis P,Hémond M,Devroede G

更新日期：1995-07-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) and ulcerative colitis (UC) are associated with considerable direct healthcare costs. There have been few comprehensive analyses of all IBD- and non-IBD comorbidities that determine direct costs in this population. METHODS:We used data from a validated cohort of patients with inflamma...

journal_title：Digestive diseases and sciences

authors： Cai W,Cagan A,He Z,Ananthakrishnan AN

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Heat shock protein 70-2 (HSP70-2) has a cytoprotective role in various conditions and also protects the gastric mucosa. Recently, polymorphism of HSP70-2 at position 1267 was suggested to be associated with carcinogenesis. We investigated the association of this polymorphism with the risk of gastric cancer i...

journal_title：Digestive diseases and sciences

authors： Shibata T,Arisawa T,Tahara T,Yoshioka D,Maruyama N,Fujita H,Kamiya Y,Nakamura M,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2009-01-01 00:00:00

abstract：:The gut endocrine gene, neurotensin (NT/N), is expressed in a strict temporally and spatially specific pattern. Utilizing a sensitive reverse transcription-polymerase chain reaction procedure, we analyzed foregut and midgut organs for NT/N expression, determined the earliest apparent time point that NT/N is expressed ...

journal_title：Digestive diseases and sciences

authors： Wang XM,Evers BM

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:An increasing number of studies have found that long non-coding RNAs (lncRNAs) play an important role in carcinogenesis and tumor progression, whereas their molecular mechanisms of function remain largely unknown. AIMS:This study was aimed to explore the biological function and underlying mechanism of a new...

journal_title：Digestive diseases and sciences

authors： He W,Zhang D,Li D,Zhu D,Geng Y,Wang Q,He J,Wu J

更新日期：2020-11-03 00:00:00

abstract：:Barrett's esophagus (BE) is a well-known premalignant condition that can be associated with the development of dysplasia and adenocarcinoma. In the past, esophagectomy was the standard treatment for patients with BE with high grade dysplasia (HGD) and early cancer (EC). However, esophagectomy is not necessarily the on...

journal_title：Digestive diseases and sciences

authors： Azarm A,Lukolic I,Shukla M,Concha-Parra R,Gress F

更新日期：2012-12-01 00:00:00

abstract：:To examine the relationship between peptic ulcer and gastric cancer, we investigated 2529 patients with peptic ulcer diagnosed from 1963 to 1975. During the follow-up period of 9-23 years, we found 38 in whom gastric cancer developed or who died of gastric cancer. Included were nine in whom gastric cancer was detected...

journal_title：Digestive diseases and sciences

authors： Lee S,Iida M,Yao T,Shindo S,Okabe H,Fujishima M

更新日期：1990-06-01 00:00:00

abstract：:In some patients, proton pump inhibitors do not abolish nocturnal gastric acidity and additional evening antisecretory medication may be required. In 16 subjects with chronic heartburn, 24-hr gastric and esophageal pH were measured at baseline and again after six days of 20 mg omeprazole alone at 08:00 hr followed by ...

journal_title：Digestive diseases and sciences

authors： Robinson M,Rodriguez-Stanley S,Ciociola AA,Filinto J,Zubaidi S,Miner PB Jr,Gardner JD

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...

journal_title：Digestive diseases and sciences

authors： Volta U,Caio G,Ghirardi C,Lungaro L,Mansueto P,Carroccio A,De Giorgio R

更新日期：2020-10-01 00:00:00

abstract：:Autoimmune hepatitis has a variable clinical phenotype, and the absence of conventional autoantibodies does not preclude its diagnosis or need for treatment. The goals of this review are to describe the frequency and nature of autoantibody-negative autoimmune hepatitis, indicate its outcome after corticosteroid treatm...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Recent data suggest the involvement of both the adaptive and the innate immune system in celiac disease (CD). However, little is known about the immune phenotype of children with CD and its alteration upon dietary intervention. AIMS:We characterized the prevalence of major interacting members of the adaptiv...

journal_title：Digestive diseases and sciences

authors： Cseh Á,Vásárhelyi B,Szalay B,Molnár K,Nagy-Szakál D,Treszl A,Vannay Á,Arató A,Tulassay T,Veres G

更新日期：2011-03-01 00:00:00

abstract：:A primary histiocytic lymphoma arising in the esophagus and its resultant spontaneous perforation is reported in a 69-year-old female. To our knowledge esophageal perforation occurring as a complication of a primary non-Hodgkin's lymphoma of the esophagus has not been previously reported. ...

journal_title：Digestive diseases and sciences

authors： Kirsch HL,Cronin DW,Stein GN,Latour F,Herrera AF

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The Gastroenterology Core Curriculum requires training in women's digestive disorders; however, requirements do not necessarily produce knowledge and competence. Our study goals were: (1) to compare perceptions of education, fellow-reported levels of competence, and attitudes towards training in wom...

journal_title：Digestive diseases and sciences

authors： Saha S,Roberson E,Richie K,Lindstrom MJ,Esposti SD,Wald A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Exercise-triggered asthma (ETA) develops when physical activity triggers asthma symptoms during or directly after exercise. In patients prone to symptoms of supra-esophageal reflux, exercise may trigger gastroesophageal reflux (GER), resulting in such symptoms. AIMS:To determine the prevalence of abnormal p...

journal_title：Digestive diseases and sciences

authors： Peterson KA,Samuelson WM,Ryujin DT,Young DC,Thomas KL,Hilden K,Fang JC

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Eradication therapies for Helicobacter pylori infection are advancing as new acid inhibitory reagents approved. The aim of this study was to assess the efficacy and safety of vonoprazan-based triple treatment. MATERIALS AND METHODS:Triple therapy with vonoprazan and two antibiotics (amoxicillin and clarithr...

journal_title：Digestive diseases and sciences

authors： Tanabe H,Ando K,Sato K,Ito T,Goto M,Sato T,Fujinaga A,Kawamoto T,Utsumi T,Yanagawa N,Ichiishi E,Otake T,Kohgo Y,Nomura Y,Ueno N,Sugano H,Kashima S,Moriichi K,Fujiya M,Okumura T

更新日期：2017-11-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is implicated in the pathology of acute liver injury and can induce lethal liver failure when simultaneously administered with D-galactosamine (D-GalN). At the present time, nonlethal liver failure, the liver injury of clinical implication, is incompletely understood following challenge by low...

journal_title：Digestive diseases and sciences

authors： Liu LM,Zhang JX,Luo J,Guo HX,Deng H,Chen JY,Sun SL

更新日期：2008-05-01 00:00:00

abstract：:The distribution of tissue kallikrein (TK) and its plasma inhibitor, kallistatin in plasma and intestinal tissue, was studied in patients with active ulcerative colitis (UC) and Crohn's disease (CD). TK was localized to goblet cells and kallistatin to epithelial cells of normal human intestine. Both proteins are visua...

journal_title：Digestive diseases and sciences

authors： Stadnicki A,Mazurek U,Gonciarz M,Plewka D,Nowaczyk G,Orchel J,Pastucha E,Plewka A,Wilczok T,Colman RW

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Intrasphincteric injection of botulinum toxin (BTX) and removable self-expanding metal stents (SEMS) have both been used for the treatment of achalasia. AIM:To compare the effectiveness and long-term outcome of SEMS placement and BTX injection in patients with achalasia. METHODS:A total of 110 patients wit...

journal_title：Digestive diseases and sciences

authors： Cai XB,Dai YM,Wan XJ,Zeng Y,Liu F,Wang D,Zhou H

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Natural language processing is a powerful technique of machine learning capable of maximizing data extraction from complex electronic medical records. METHODS:We utilized this technique to develop algorithms capable of "reading" full-text radiology reports to accurately identify the presence of fatty live...

journal_title：Digestive diseases and sciences

authors： Redman JS,Natarajan Y,Hou JK,Wang J,Hanif M,Feng H,Kramer JR,Desiderio R,Xu H,El-Serag HB,Kanwal F

更新日期：2017-10-01 00:00:00

abstract：:The effect of ischemia-reperfusion and 48-hr fasting on apoptosis was characterized in rat gastric mucosa and compared to small intestinal mucosa. Under halothane anesthesia, the celiac artery or superior mesenteric artery in the rat was occluded for 60 min followed by reperfusion. Occlusion of the celiac artery reduc...

journal_title：Digestive diseases and sciences

authors： Fukuyama K,Iwakiri R,Noda T,Kojima M,Utsumi H,Tsunada S,Sakata H,Ootani A,Fujimoto K

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To compare the Rosemont criteria, which are graded features chosen by experts in 2007, versus the conventional criteria, which require ≥ 3-5 of the 9 features that are "counted as equal," for the diagnosis of chronic pancreatitis by EUS. METHODS:This is a retrospective cohort study. EUS examinations were sco...

journal_title：Digestive diseases and sciences

authors： D'Souza SL,Anderson MA,Korsnes SJ,Elmunzer BJ,Piraka C,Menees S,Wamsteker EJ,Kwon RS,Scheiman JM,Elta GH

更新日期：2015-12-01 00:00:00

abstract：:The study was undertaken to examine regional differences in the concentrations of five regulatory peptides in the human colonic mucosa. Biopsies were obtained during routine colonoscopy from 33 patients whose colonic mucosa was macroscopically and histologically normal. Regulatory peptides were extracted, and measured...

journal_title：Digestive diseases and sciences

authors： Calam J,Ghatei MA,Domin J,Adrian TE,Myszor M,Gupta S,Tait C,Bloom SR

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND/AIM:Familial Mediterranean fever (FMF), the most frequent periodic fever syndrome, is an autosomal recessive inherited disease that predominantly affects eastern Mediterranean populations. Fetuin-A is a well known negative acute-phase protein. Studies of this glycoprotein as a marker of inflammation in FMF a...

journal_title：Digestive diseases and sciences

authors： Oncu K,Yazgan Y,Tanoglu A,Kaplan M,Ermis F,Ipcioglu OM,Kara M,Kucuk I,Ozari HO

更新日期：2013-11-01 00:00:00

abstract：:Mutations in the gene encoding the CYP2C-19 enzyme for PPI metabolism have been shown to enhance the chance for a cure in a H. pylori-positive patients using a two-week dual-therapy regimen involving omeprazole and amoxicillin. However, the impact of CYP2C-19 genetic polymorphism on eradication rates of a one-week tri...

journal_title：Digestive diseases and sciences

authors： Miwa H,Misawa H,Yamada T,Nagahara A,Ohtaka K,Sato N

更新日期：2001-11-01 00:00:00

abstract：:The incidence of colorectal adenocarcinoma increased in the five major ethnic groups in Hawaii, but more in men than women. The highest rates were in the Chinese and Japanese. The site-specific time trend patterns revealed that the greatest increase occurred in rectosigmoid cancer, followed by cancer of the sigmoid co...

journal_title：Digestive diseases and sciences

authors： Nomura AM,Kolonel LN,Hinds MW

更新日期：1981-12-01 00:00:00