Free radical scavengers prevent reflux esophagitis in rats.

abstract：BACKGROUND AND AIMS:Avoidance of gluten is critical for individuals with celiac disease (CD), but there is also concern that "extreme vigilance" to a strict gluten-free diet may increase symptoms such as anxiety and fatigue, and therefore, lower quality of life (QOL). We examined the associations of QOL with energy lev...

journal_title：Digestive diseases and sciences

authors： Wolf RL,Lebwohl B,Lee AR,Zybert P,Reilly NR,Cadenhead J,Amengual C,Green PHR

更新日期：2018-06-01 00:00:00

abstract：:Autoregulation of blood flow in the denervated, autoperfused dog stomach was studied before and during local intraarterial infusion of histamine. Histamine caused an increase in gastric blood flow and oxygen uptake. The increased oxygen uptake was due entirely to an increased blood flow, ie, oxygen extraction was not ...

journal_title：Digestive diseases and sciences

authors： Perry MA,Murphree D,Granger DN

更新日期：1982-08-01 00:00:00

abstract：:This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healin...

journal_title：Digestive diseases and sciences

authors： Di Febo G,Miglioli M,Calò G,Biasco G,Luzza F,Gizzi G,Cipollini F,Rossi A,Barbara L

更新日期：1985-02-01 00:00:00

abstract：:To date few therapies have been shown to reliably prevent the evolution of Crohn's disease (CD). The traditional Chinese medicine, Tripterygium wilfordii Hook F (TWHF), has both immunomodulatory and anti-inflammatory activities. Our aim was to investigate the potential efficacy of T2, the major constituent of extracts...

journal_title：Digestive diseases and sciences

authors： Ren J,Tao Q,Wang X,Wang Z,Li J

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00

abstract：:Nearly all chronic anal fissures occur in the posterior midline of the anal canal. However, some of them are in the anterior midline and are rarely double or in the lateral anal walls. The aim of this study was to determine if the clinical, manometric and endosonographic characteristics in patients with chronic anal f...

journal_title：Digestive diseases and sciences

authors： Pascual M,Parés D,Pera M,Courtier R,Gil MJ,Puig S,Serrano A,Andreu M,Grande L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Antiglycan antibodies have recently been reported to be associated with Crohn's disease (CD). These antibodies include anti-Saccharomyces cerevisiae mannan antibodies (ASCA), anti-laminariobioside carbohydrate antibodies (ALCA), anti-chitobioside carbohydrate antibodies (ACCA), and anti-mannobioside carbohyd...

journal_title：Digestive diseases and sciences

authors： Koutroubakis IE,Drygiannakis D,Tsirogianni A,Oustamanolakis P,Karmiris K,Papamichael K,Mantzaris GJ,Kouroumalis EA

更新日期：2011-03-01 00:00:00

abstract：:Data about colonic mucosa transport of short-chain fatty acids in cirrhotic patients are still lacking. The aim of the present study was to compare the rectal mucosa transport of n-butyrate and its effect on transport of other electrolytes and endoluminal pH in normal subjects and in cirrhotic patients by using a rect...

journal_title：Digestive diseases and sciences

authors： Onori L,Pimpo MT,Palumbo GC,Gili L,Marchetti G,Saltarelli P,Aggio A,Frieri G

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is an established causal factor for non-cardia gastric cancer. H. pylori negative gastric cancer prevalence among US patients is unclear. METHODS:This retrospective cohort study examined H. pylori prevalence among consecutive patients with incident non-cardia gastric adenocarci...

journal_title：Digestive diseases and sciences

authors： Nguyen TH,Mallepally N,Hammad T,Liu Y,Thrift AP,El-Serag HB,Tan MC

更新日期：2020-08-01 00:00:00

abstract：:Twenty-eight patients with delayed gastric emptying as measured by an abnormal barium "burger" were treated with metoclopramide in a randomized, double-blind fashion. Five had diabetic gastroparesis, four had undergone vagotomy and pyloroplasty, and 19 were idiopathic. Patients received either metoclopramide or placeb...

journal_title：Digestive diseases and sciences

authors： Perkel MS,Moore C,Hersh T,Davidson ED

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Small intestinal bacterial overgrowth (SIBO) is regarded as the major risk factor of bacterial translocation. Few studies have investigated the direct relation between SIBO and translocation in cirrhotic patients. The purpose of this study is to examine the correlation between SIBO and bacterial DNA in the p...

journal_title：Digestive diseases and sciences

authors： Jun DW,Kim KT,Lee OY,Chae JD,Son BK,Kim SH,Jo YJ,Park YS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori vacuolating cytotoxin, VacA, stimulates apoptosis via a mitochondria-dependent pathway. VacA induces apoptosis via activation of the pro-apoptotic B-cell lymphoma (Bcl)-2 family proteins, Bcl-2-associated X protein (Bax) and Bcl-2 homologous antagonist/killer (Bak), while the implication ...

journal_title：Digestive diseases and sciences

authors： Matsumoto A,Isomoto H,Nakayama M,Hisatsune J,Nishi Y,Nakashima Y,Matsushima K,Kurazono H,Nakao K,Hirayama T,Kohno S

更新日期：2011-04-01 00:00:00

abstract：:Endoscopic photodynamic therapy with hematoporphyrin derivative was used in the primary treatment of 54 patients with inoperable gastrointestinal neoplasms. Patients were divided into three groups including 24 with esophageal squamous cell carcinoma, 14 with adenocarcinoma of the stomach or lower third of the esophagu...

journal_title：Digestive diseases and sciences

authors： Patrice T,Foultier MT,Yactayo S,Adam F,Galmiche JP,Douet MC,Le Bodic L

更新日期：1990-05-01 00:00:00

abstract：:The incidence of colorectal adenocarcinoma increased in the five major ethnic groups in Hawaii, but more in men than women. The highest rates were in the Chinese and Japanese. The site-specific time trend patterns revealed that the greatest increase occurred in rectosigmoid cancer, followed by cancer of the sigmoid co...

journal_title：Digestive diseases and sciences

authors： Nomura AM,Kolonel LN,Hinds MW

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND AND AIM:Second harmonic generation (SHG) is a novel imaging technology that could provide optical biopsy during endoscopy with advantages over current technology. SHG has the unique ability to evaluate the amount of extracellular matrix collagen protein and its alignment. METHODS:Hematoxylin- and eosin-stai...

journal_title：Digestive diseases and sciences

authors： Birk JW,Tadros M,Moezardalan K,Nadyarnykh O,Forouhar F,Anderson J,Campagnola P

更新日期：2014-07-01 00:00:00

abstract：:Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...

journal_title：Digestive diseases and sciences

authors： Guo JP,Maurer AH,Fisher RS,Parkman HP

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Data on alcohol-related HCC are limited. AIMS:Our aim was to describe the incidence, management, and prognosis of alcohol compared to Hepatitis C (HCV)-related HCC at a national level. METHODS:Incident cases of HCC were identified in French healthcare databases between 2009 and 2012 and analyzed retrospect...

journal_title：Digestive diseases and sciences

authors： Costentin CE,Sogni P,Falissard B,Barbare JC,Bendersky N,Farges O,Goutte N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Determining the risk stratification of nonvariceal upper gastrointestinal bleeding (NVUGIB) plays a vital role in treating upper gastrointestinal bleeding (UGIB). Traditional scores like Glasgow-Blatchford score (GBS), Rockall score (RS), and AIMS65 score have been widely utilized in UGIB practice, however e...

journal_title：Digestive diseases and sciences

authors： Yue W,Liu Y,Jiang W,Huang J,Liu J

更新日期：2020-06-24 00:00:00

abstract：:Hepatocyte growth factor plays a key role in liver regeneration but the role of liver in its synthesis in acute liver failure is unclear. We therefore measured hepatic expression of hepatocyte growth factor mRNA in this condition in comparison to H3 histone mRNA, a marker of cellular proliferation. Hepatocyte growth f...

journal_title：Digestive diseases and sciences

authors： Harrison P,Gove C,Bomford A

更新日期：2000-10-01 00:00:00

abstract：:A case of hypereosinophilic syndrome with eosinophilic colitis, eosinophilic cholecystitis, and increased serum levels of interleukin-5 (IL-5) and soluble interleukin-2 receptor (sIL-2R) is reported. Immunohistochemical studies of cholecystectomy and colon biopsy specimens with monoclonal antibodies, which are specifi...

journal_title：Digestive diseases and sciences

authors： Tajima K,Katagiri T

更新日期：1996-02-01 00:00:00

abstract：:The effect of psyllium hydrophilic mucilloid (PHM) when used as a laxative and/or stool softener on serum cholesterol concentrations was examined in 176 ambulatory elderly participants attending a health screening program. The change in one-year serum cholesterol concentration in subjects using PHM was compared with t...

journal_title：Digestive diseases and sciences

authors： Stewart RB,Hale WE,Moore MT,May FE,Marks RG

更新日期：1991-03-01 00:00:00

abstract：:Fructose and lactose malabsorption are characterized by impaired duodenal fructose transport or by the deficiency of mucosal lactase, respectively. As a consequence, the nonabsorbed saccharides reach the colon, where they are broken down by bacteria to short fatty acids, CO2, and H2. Bloating, cramps, osmotic diarrhea...

journal_title：Digestive diseases and sciences

authors： Ledochowski M,Widner B,Sperner-Unterweger B,Propst T,Vogel W,Fuchs D

更新日期：2000-07-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：:It has previously been shown that mucosal nitric oxide synthase (NOS) is involved in acid-induced duodenal mucosal alkaline secretion. The primary aim of the present study was to elucidate which isoform of NOS is responsible in rats. Immunohistochemistry showed that inducible NOS (iNOS) was constitutively expressed in...

journal_title：Digestive diseases and sciences

authors： Holm M,Powell T,Casselbrant A,Johansson B,Fändriks L

更新日期：2001-08-01 00:00:00

abstract：:Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supplemented with 0.2% DOC, develop colonic inflammation associated with in...

journal_title：Digestive diseases and sciences

authors： Bernstein H,Holubec H,Bernstein C,Ignatenko NA,Gerner E,Dvorak K,Besselsen D,Blohm-Mangone KA,Padilla-Torres J,Dvorakova B,Garewal H,Payne CM

更新日期：2007-03-01 00:00:00

abstract：:Published clinical trials (N = 56) of antisecretory drugs in the treatment of benign gastric ulcer were reviewed. Composite healing rates for various drug regimens were calculated using a method previously described for duodenal ulcer. Healing rates were compared with data on suppression of intragastric acidity to see...

journal_title：Digestive diseases and sciences

authors： Howden CW,Jones DB,Peace KE,Burget DW,Hunt RH

更新日期：1988-05-01 00:00:00

abstract：AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...

journal_title：Digestive diseases and sciences

authors： Bafford AC,Latushko A,Hansraj N,Jambaulikar G,Ghazi LJ

更新日期：2017-08-01 00:00:00

abstract：:Translocation of bacteria and endotoxtin has long been documented in obstructive jaundice, and altered intestinal barrier function is considered to be one of the important mechanisms for this phenomenon. The regulation of gastrointestinal mucosal response to injury is thus of important clinical as well as biological r...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Chen HS,Ho HT,Sheen CC,Chen WJ,Eng HL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation ...

journal_title：Digestive diseases and sciences

authors： Park SC,Keum B,Seo YS,Kim YS,Jeen YT,Chun HJ,Um SH,Kim CD,Ryu HS

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00