Efficacy of 5-aminosalicylic acid enemas versus hydrocortisone enemas in ulcerative colitis.

Abstract:

:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, sigmoidoscopic, and histologic criteria for 5-ASA treatment. Other aspects have been investigated, such as retrograde spread of enemas which have been shown to reach the left colon. No nephrotoxicity was detected. The long term experience confirmed the preliminary positive results.

journal_name

Dig Dis Sci

authors

Campieri M,Gionchetti P,Belluzzi A,Brignola C,Migaldi M,Tabanelli GM,Bazzocchi G,Miglioli M,Barbara L

doi

10.1007/BF01312467

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

67S-70S

issue

12 Suppl

eissn

0163-2116

issn

1573-2568

journal_volume

32

pub_type

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