Abstract:
:A new extracorporeal piezoelectric lithotripter was tested for its gallstone disintegration capability. A total of 177 surgically removed gallbladder stones were submitted to piezoelectric shock-wave treatment. Prior to shock-wave application, the diameter, weight, and volume of all the stones and CT density and MR signal intensity of selected stones were determined. After shock-wave application, the chemical composition of the stones was investigated by x-ray diffractometry and/or infrared spectrometry. All the stones (maximum diameter 6-30 mm) were successfully fragmented; calculi with a maximum diameter of 17 mm, a maximum weight of 1800 mg, and a maximum volume of 2 cc were regularly disintegrated into fragments less than or equal to 4 mm. The number of shock waves required correlated most closely with volume (r = 0.82, P less than 0.001), weight (r = 0.81, P less than 0.001) and, to a somewhat lesser degree, diameter (r = 0.62, P less than 0.001). No correlation was found between the chemical composition, CT density, or MR intensity of the calculi and the number of pulses needed for fragmentation.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Ell C,Kerzel W,Langer H,Heyder N,Foerster E,Domschke Wdoi
10.1007/BF01536364subject
Has Abstractpub_date
1989-07-01 00:00:00pages
1006-10issue
7eissn
0163-2116issn
1573-2568journal_volume
34pub_type
杂志文章abstract::This study evaluates the hypothesis that cerulein relaxes the sphincter of Oddi (SO) via nitric oxide (NO). The spontaneous motility and the response to cerulein on the canine SO were recorded using a constant-perfusion technique. N(G)-L-arginine-methyl-ester (L-NAME) increased the spontaneous motility and dose-depend...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018811124191
更新日期:1998-03-01 00:00:00
abstract::Several gastrointestinal hormones have been found in the intestinal lumen, but as yet their physiologic role is not yet clear. We have previously shown in anesthesized animals that electrical vagal stimulation provokes simultaneous intraluminal release of serotonin (5-HT) and substance P (SP). The aim of this study wa...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297056
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:Hypoxia is an important factor in malignant tumors, and glycolysis is a major metabolic contributor in their development. Glycolytic enzymes have gained increasing attention as potential therapeutic targets because they are associated with cancer-specific metabolism. Fructose-bisphosphate aldolase A (ALDOA),...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-019-05642-2
更新日期:2019-11-01 00:00:00
abstract::Systemic sclerosis (SSc) is a connective tissue disorder of unknown etiology characterized by fibrosis and vascular obliteration in the skin, gastrointestinal tract, lungs, and heart. Our aim was to investigate the autoantibody profile in patients with esophageal involvement of SSc and to describe the relationship bet...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-007-9809-1
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Reflux-like dyspepsia (RLD), where predominant epigastric pain is associated with heartburn and/or regurgitation, is a common clinical syndrome in both primary and specialty care. Because symptom frequency and severity vary, overlap among gastroesophageal reflux disease (GERD), non-erosive reflux disease (NE...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1708-9
更新日期:2011-10-01 00:00:00
abstract::In a randomized trial, 75 patients with an endoscopically confirmed and symptomatic duodenal (N = 50) or prepyloric (N = 25) ulcer were allocated to cimetidine treatment (1 g/day) either regularly for four weeks (standard treatment group) or regularly for a minimum of one week and thereafter only until the symptoms we...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01347901
更新日期:1986-01-01 00:00:00
abstract::The effects of chronic normovolemic anemia on gastric microcirculation and gastric mucosal susceptibility to ethanol-induced gastric damage were investigated in anesthetized rats. Blood exchange by a plasma expander during four consecutive days rendered the animals anemic with a 34% decrease in the baseline hematocrit...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02087418
更新日期:1994-04-01 00:00:00
abstract::Serum levels of immunosuppressive acidic protein (IAP) were determined in 68 patients undergoing resection of colorectal cancer and 21 healthy subjects. Eighteen patients had perioperative transfusion of allogeneic blood (transfused patients) and 50 patients had no blood transfusion (nontransfused patients). Transfuse...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
doi:10.1023/a:1026619111897
更新日期:1999-08-01 00:00:00
abstract::Aging and gastrointestinal malignancies, including that of the stomach are associated with increased activation of EGF-receptor (EGFR). Although the intracellular events that regulate this process are poorly understood, we hypothesize that loss of ERRP (EGFR-related protein; GenBank accession number AF187818), a recen...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1023078924686
更新日期:2003-05-01 00:00:00
abstract::The initiating mechanisms involved in colonic injury are currently unknown. The goal of the current study was to examine the role of the inflammatory mediators reactive oxygen metabolites and proteases in an ex vivo model of selective epithelial permeability. Rats were prepared with exteriorized colonic chambers to wh...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02209017
更新日期:1995-10-01 00:00:00
abstract::Idiopathic chronic constipation has been correlated to neural abnormalities that consist of a reduced number of myenteric plexus neurons and a decreased concentration of VIP-positive nerve fibers within the circular muscle. Recent studies hypothesized the involvement of nitric oxide in motility disorders of the human ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02063253
更新日期:1995-11-01 00:00:00
abstract::Cytomegalovirus (CMV) inclusions were found at colonic perforation sites in three patients with clinical settings suggesting a compromised immunologic status. This could be interpreted as: (1) CMV was an etiologic agent in these perforations; or (2) CMV was an opportunistic superinfection in areas of preexisting infla...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297124
更新日期:1979-05-01 00:00:00
abstract::Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02100135
更新日期:1996-12-01 00:00:00
abstract:BACKGROUND:Accumulating evidence suggests that Foxp3+ regulatory T (Treg) cells act as inhibitory mediators of inflammation; however, the in vivo mechanism underlying this protection remains elusive in liver diseases. AIMS:To clarify the in vivo role of Foxp3+ Treg cells in liver fibrosis, we used the DEREG mouse, whi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-014-3438-2
更新日期:2015-07-01 00:00:00
abstract::This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/b:ddas.0000026310.71607.4c
更新日期:2004-04-01 00:00:00
abstract::We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measurements were made of LES relaxation before and after intravenous administr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01300200
更新日期:1987-10-01 00:00:00
abstract::A 24-year-old white woman presented with abdominal discomfort associated with a firm, nonpulsatile hepatic mass. Radiological examination, which included radionuclide liver scan, abdominal ultrasonography, computed tomography, and hepatic angiography, demonstrated a large, globular, multilocular cyst arising from the ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296059
更新日期:1986-08-01 00:00:00
abstract::In toxic liver injury, proliferation of preexisting hepatocytes helps restore liver mass and function. While loss of liver mass per se stimulates hepatocyte proliferation, exogenous mitogens have a potential role in enhancing liver regeneration. The aim of this study was to characterize the effects of the mitogen, tri...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-006-9275-1
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Hepatoportal sclerosis (HPS) is a clinicopathologic condition that is clinically characterized by portal hypertension (varices and portosystemic collateral vessels), splenomegaly and pancytopenia, in the absence of cirrhosis. Although the etiology is obscure, a number of theories such as immunologic...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1580-7
更新日期:2011-07-01 00:00:00
abstract::This study was undertaken to investigate the effect of ingestion of 80 g Vivonex on gallbladder volume, plasma cholecystokinin (CCK), and pancreatic polypeptide (PP) in eight healthy volunteers and to compare the results with those obtained after ingestion of 60 ml corn oil. Gallbladder volumes were measured by ultras...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296686
更新日期:1987-01-01 00:00:00
abstract::Bacterial infection remains a leading cause of mortality and morbidity for patients with cirrhosis, with hospitalization, alterations in the intestinal microbiota, and therapeutic drugs all implicated in its development. Bacterial infections also remain the most common precipitant of acute-on-chronic liver failure, wi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-019-05943-6
更新日期:2020-01-01 00:00:00
abstract::Gastric antral vascular ectasia was endoscopically diagnosed in seven patients. Pathologic characteristics of this entity were defined retrospectively, by studying endoscopic pinch biopsy slides from these seven patients and antrectomy specimens from five patients. A scoring system was developed, and the seven patient...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01540274
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND/AIM:Familial Mediterranean fever (FMF), the most frequent periodic fever syndrome, is an autosomal recessive inherited disease that predominantly affects eastern Mediterranean populations. Fetuin-A is a well known negative acute-phase protein. Studies of this glycoprotein as a marker of inflammation in FMF a...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-013-2814-7
更新日期:2013-11-01 00:00:00
abstract::Twenty-four patients with chronic active HCV infection, nonresponders to a previous treatment cycle with recombinant interferon-alpha (r-IFNA), underwent retreatment with leukocyte (LE-) IFN-alpha. This was administered at the dose of 3 MU three times a week, for either six months (group A) or 12 months (group B). All...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1023/a:1026693901012
更新日期:1998-10-01 00:00:00
abstract::The current cost of endoscopically screening patients with gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) is considerable. A nonendoscopic device that allows for screening of these patients would offer significant cost savings. This pilot study evaluates the utility of cytologically diagnosing BE ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1012771328187
更新日期:2001-12-01 00:00:00
abstract::The hydrogen (H2) lactose breath test (BT) is a test commonly used for the diagnosis of hypolactasia. However, its sensitivity is not always good. In the last few years, the new Quick Lactase Test (QLT) has been developed for endoscopic diagnosis of adult-type hypolactasia. The aim of this study was to compare the eff...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-007-0027-7
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Microinflammation frequently develops in chronic uremia with pathological intestinal changes. However, the relationship between gut bacterial translocation and microinflammation in uremia has not been widely investigated. AIM:This study aimed to investigate whether gut microbiome dysbiosis and translocation...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-012-2242-0
更新日期:2012-11-01 00:00:00
abstract::The main objective of our studies has been to optimize the effects of monoclonal antibodies (MAbs) and other immunosuppressive reagents to enhance organ graft survival. One such agent is OKT3, a MAb that is directed against the CD3 component of the human T-cell receptor (TCR) complex. Treatment of a rejection episode ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/BF02063942
更新日期:1995-01-01 00:00:00
abstract::Achalasia is an esophageal motility disorder of unknown etiology. Several studies suggest possible herpes or measles virus etiology, but results are inconclusive. The aim of this study was to test whether herpesvirus (HV), measles (MV), or human papilloma virus (HPV) sequences could be detected in myotomy specimens fr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018805600276
更新日期:1997-02-01 00:00:00
abstract::A sustained increase in cytosolic Ca2+ can damage gastric mucosal cells. The present study has examined the role of Ca2+ in thromboxane B2 (TXB2)-mediated damage of rabbit isolated gastric mucosal cells. Cells were isolated from rabbit oxyntic mucosa by collagenase-EDTA digestion. Cell metabolic activity and cell dama...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02208674
更新日期:1995-09-01 00:00:00