Diagnostic Ability of Endoscopic Bile Cytology Using a Newly Designed Biliary Scraper for Biliary Strictures.

Abstract:

BACKGROUND:A new device with metallic wires for scrape cytology was developed. AIMS:To compare the diagnostic performance of scrape cytology and conventional cytology during endoscopic retrograde cholangiopancreatography for biliary strictures. METHODS:A total of 420 cases with biliary stricture underwent transpapillary bile cytology. Among them, there are 79 cases with scrape cytology using the new device (scrape group) and 341 cases with conventional cytology (control group). Seventy-two and 174 cases underwent biliary biopsy at the same time as bile cytology in the scrape and control group, respectively. RESULTS:The sensitivity for malignancy of bile cytology in the scrape and control group was 41.2% [pancreatic cancer (PC): 23.1%, biliary cancer (BC): 52.5%] and 27.1% (PC: 16.3%, BC: 38.0%), respectively (P = 0.023). When analyzed PC and BC, respectively, there was no significant difference between the two groups. In the both groups, the sensitivity was significantly higher for BC than PC. In the scrape group, there was no difference in the sensitivity between cytology and biopsy [39.7% (PC: 17.4%, BC: 55.3%)], but in the control group, a significantly lower sensitivity was observed with cytology than biopsy (36.4% (PC: 19.7%, BC: 50.0%)) (P = 0.046). When analyzed PC and BC, respectively, there was no significant difference between cytology and biopsy. The sensitivity of combined cytology and biopsy was 55.6% (PC: 30.4%, BC: 71.1%) in the scrape group and 47.0% (PC: 24.6%, BC: 64.3%) in the control group. CONCLUSION:Scrape bile cytology for biliary strictures may be superior to conventional cytology.

journal_name

Dig Dis Sci

authors

Nakahara K,Michikawa Y,Morita R,Suetani K,Morita N,Sato J,Tsuji K,Ikeda H,Matsunaga K,Watanabe T,Matsumoto N,Kobayashi S,Otsubo T,Itoh F

doi

10.1007/s10620-018-5217-y

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

241-248

issue

1

eissn

0163-2116

issn

1573-2568

pii

10.1007/s10620-018-5217-y

journal_volume

64

pub_type

杂志文章
  • Fructose-Bisphosphate Aldolase A Regulates Hypoxic Adaptation in Hepatocellular Carcinoma and Involved with Tumor Malignancy.

    abstract:BACKGROUND:Hypoxia is an important factor in malignant tumors, and glycolysis is a major metabolic contributor in their development. Glycolytic enzymes have gained increasing attention as potential therapeutic targets because they are associated with cancer-specific metabolism. Fructose-bisphosphate aldolase A (ALDOA),...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-019-05642-2

    authors: Li X,Jiang F,Ge Z,Chen B,Yu J,Xin M,Wang J,An L,Wei J,Wu L

    更新日期:2019-11-01 00:00:00

  • Immune escape mechanism: defective resting and stimulated leukocyte-endothelium interaction in hepatocellular carcinoma of the rat.

    abstract::Hepatocellular carcinoma represents an increasing therapeutic challenge due to its high incidence and early metastasis. Numerous studies have demonstrated the influence of the vascular system on tumor growth and development. In addition, the role of leukocyte-endothelium interaction in tumor vessels is of particular s...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/b:ddas.0000030100.05979.b7

    authors: Maksan SM,Araib PM,Ryschich E,Gebhard MM,Schmidt J

    更新日期:2004-05-01 00:00:00

  • Focused Education Increases Hepatocellular Cancer Screening in Patients with Cirrhosis Regardless of Functional Health Literacy.

    abstract:BACKGROUND:Health education interventions are successful in modifying lifestyle. Functional health literacy (FHL) can determine patient adherence to clinic visits and procedures and may adversely impact the success of these interventions. AIMS:We sought to evaluate the hypothesis that a health education intervention w...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-020-06583-x

    authors: Shaw J,Patidar KR,Reuter B,Hajezifar N,Dharel N,Wade JB,Bajaj JS

    更新日期:2020-09-05 00:00:00

  • Effect of isopropamide on response to oral cimetidine in patients with Zollinger--Ellison syndrome.

    abstract::Patients with Zollinger-Ellison syndrome whose gastric acid secretion or symptoms were not controlled by cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of cimetidine, used either alone or in combination with a long-acting anticholinergic agent,...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296756

    authors: McCarthy DM,Hyman PE

    更新日期:1982-04-01 00:00:00

  • Recalibrating the Child-Turcotte-Pugh Score to Improve Prediction of Transplant-Free Survival in Patients with Cirrhosis.

    abstract:BACKGROUND:The Child-Turcotte-Pugh (CTP) score is a widely used and validated predictor of long-term survival in cirrhosis. However, the cutpoints for stratifying laboratory variables in CTP have never been validated. OBJECTIVE:The objective of this study was to identify evidence-based cutpoints for the CTP laboratory...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-016-4239-6

    authors: Kaplan DE,Dai F,Skanderson M,Aytaman A,Baytarian M,D'Addeo K,Fox R,Hunt K,Knott A,Mehta R,Pedrosa M,Pocha C,Valderrama A,Taddei T,VOCAL Study Group.

    更新日期:2016-11-01 00:00:00

  • Short-Term Effects of Relamorelin on Descending Colon Motility in Chronic Constipation: A Randomized, Controlled Trial.

    abstract:BACKGROUND:The pentapeptide ghrelin agonist, relamorelin, accelerates colonic transit in patients with chronic constipation (CC). In a murine model, relamorelin decreased excitability of colonic circular smooth muscle cells and colonic intraluminal pressure. AIM:To determine short-term effects of relamorelin on coloni...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10620-015-3876-5

    authors: Acosta A,Camilleri M,Busciglio I,Boldingh A,Nelson AD,Burton D

    更新日期:2016-03-01 00:00:00

  • Role of nitric oxide in oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation.

    abstract::The present study aimed to investigate the role of nitric oxide on the oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, a nitric oxide donor, sodium nitroprusside, and superoxide dismutase were...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018886919532

    authors: Kim H,Kim KH

    更新日期:1998-05-01 00:00:00

  • Regional differences in concentrations of regulatory peptides in human colon mucosal biopsy.

    abstract::The study was undertaken to examine regional differences in the concentrations of five regulatory peptides in the human colonic mucosa. Biopsies were obtained during routine colonoscopy from 33 patients whose colonic mucosa was macroscopically and histologically normal. Regulatory peptides were extracted, and measured...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01537267

    authors: Calam J,Ghatei MA,Domin J,Adrian TE,Myszor M,Gupta S,Tait C,Bloom SR

    更新日期:1989-08-01 00:00:00

  • Evaluation of cytoprotection against ethanol-induced injury in gastric mucosa pretreated with misoprostol, cimetidine, or placebo.

    abstract::The authors have developed a primate model for evaluating cytoprotection against alcohol-induced injury in gastric mucosa pretreated with antiulcer agents. In the present study, groups of squirrel monkeys received either a single oral dose of misoprostol (500 or 200 micrograms/kg), cimetidine (3 or 6 mg/kg), placebo, ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01309333

    authors: Liss RH,Letourneau RJ,Schepis JP

    更新日期:1986-02-01 00:00:00

  • Pyloric deformation from peptic disease. Radiographic evidence for incompetence rather than obstruction.

    abstract::We have used double-contrast radiographic techniques to clarify what changes in the configuration and movements of the gastroduodenal junction result when peptic lesions involve the distal gastric segment between the proximal (PPL) and the distal pyloric muscle loop (DPL). Among 50 cases of pyloric ulceration diagnose...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01540562

    authors: Lu CC,Schulze-Delrieu K

    更新日期:1990-12-01 00:00:00

  • Continuous intraoperative monitoring of hepatic blood perfusion using a noninvasive surface electrode.

    abstract::Continuous noninvasive measurement of local blood flow at one or more chosen sites will be useful during experiments on the liver, during liver surgery, or after hepatic transplantation. We have compared a Clark-type flow-dependent oxygen electrode having a 3-mm-diameter cathode applied to the surface of rabbit liver ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01537421

    authors: Piasecki C,Seifalian AM

    更新日期:1990-03-01 00:00:00

  • Effects of octreotide and erythromycin on gastric myoelectrical and motor activities in patients with gastroparesis.

    abstract::Simultaneous recordings of gastric manometry and myoelectrical activity were made in 10 patients with gastroparesis. Intravenous erythromycin (100 mg) was administered in the fasting state for a period of 30 min. Subcutaneous injection of octreotide (100 microg) was administered before one of the four identical test m...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018876021156

    authors: Chen JD,Lin ZY,Edmunds MC 3rd,McCallum RW

    更新日期:1998-01-01 00:00:00

  • Polymorphism of IL-8 in 251 allele and gastric cancer susceptibility: a meta-analysis.

    abstract:BACKGROUND:The relationship of gastric cancer to the presence of interleukin-8 (IL-8) 251 T/A has been reported with conflicting results. AIM:To further explore the association of IL-8 251 allele polymorphism with gastric cancer susceptibility. METHODS:We performed an extensive search of relevant studies and carried ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s10620-009-0978-y

    authors: Wang J,Pan HF,Hu YT,Zhu Y,He Q

    更新日期:2010-07-01 00:00:00

  • Autophagy Genes of Host Responds to Disruption of Gut Microbial Community by Antibiotics.

    abstract:BACKGROUND:Defective autophagic machinery, such as that in Crohn's disease patients homozygous for ATG16L1 risk allele, is associated with alteration of resident gut bacterial communities. However, whether or not host autophagy responds to changes in the resident gut microbial community is not known. Here, we investiga...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-017-4589-8

    authors: Singh SB,Wilson M,Ritz N,Lin HC

    更新日期:2017-06-01 00:00:00

  • Diabetes mellitus, and not obesity, is associated with lower survival following liver transplantation.

    abstract:BACKGROUND AND AIMS:The impact of obesity on survival following liver transplantation is unclear, and existing studies report conflicting results. Our current study aims to further delineate the impact of obesity using population-based registry data from the USA. METHODS:All US adult liver transplant recipients from 2...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3469-8

    authors: Wong RJ,Cheung R,Perumpail RB,Holt EW,Ahmed A

    更新日期:2015-04-01 00:00:00

  • MiR-27a/b Regulates Liver Regeneration by Posttranscriptional Modification of Tmub1.

    abstract:BACKGROUND:Transmembrane and ubiquitin-like domain-containing 1 protein (Tmub1) negatively regulates liver regeneration. However, whether this regulation involves posttranscriptional modification of Tmub1 expression is unknown. AIM:The aim of the study was to investigate whether microRNA (miR)-27a/b regulates posttran...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-5113-5

    authors: Lan X,Li G,Liu H,Fu H,Chen P,Liu M

    更新日期:2018-09-01 00:00:00

  • Ultra-short Celiac Disease Is a Distinct and Milder Phenotype of the Disease in Children.

    abstract:BACKGROUND AND AIMS:Approximately 10% of children with celiac disease (CD) have ultra-short celiac disease (USCD), where histological abnormalities are limited to the duodenal bulb. The aim of our retrospective study was to identify clinical and serological characteristics at baseline and at follow-up of children with ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-5323-x

    authors: Doyev R,Cohen S,Ben-Tov A,Weintraub Y,Amir A,Galai T,Moran-Lev H,Yerushalmy-Feler A

    更新日期:2019-01-01 00:00:00

  • Vitamin D deficiency and corticosteroid use are risk factors for low bone mineral density in inflammatory bowel disease patients.

    abstract:BACKGROUND:As several factors can contribute to low bone mineral density (BMD), we investigated the role of vitamin D in low BMD while controlling for other risk factors in inflammatory bowel diseases (IBD) patients. METHODS:We conducted a prospective cross-sectional study between 2008 and 2012 in adult IBD patients. ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3102-x

    authors: Abraham BP,Prasad P,Malaty HM

    更新日期:2014-08-01 00:00:00

  • Interleukin-1β Mediates β-Catenin-Driven Downregulation of Claudin-3 and Barrier Dysfunction in Caco2 Cells.

    abstract:BACKGROUND:IL-1β is a cytokine involved in mediating epithelial barrier dysfunction in the gut. It is known that IL-1β mediates activation of non-muscle myosin light chain kinase in epithelial cells, but the precise mechanism by which epithelial barrier dysfunction is induced by IL-1β is not understood. METHODS AND RE...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-016-4145-y

    authors: Haines RJ,Beard RS Jr,Chen L,Eitnier RA,Wu MH

    更新日期:2016-08-01 00:00:00

  • Dientamoeba fragilis, a protozoan parasite in adult members of a semicommunal group.

    abstract::Dientamoeba fragilis is an intestinal protozoan parasite associated with gastrointestinal symptoms. This study was undertaken in a semicommunal group reported to have a high prevalence of this parasite. Stools were collected from 81 adult group members. Intestinal parasites were observed in stool specimens of 45 (56%)...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01324950

    authors: Millet V,Spencer MJ,Chapin M,Stewart M,Yatabe JA,Brewer T,Garcia LS

    更新日期:1983-04-01 00:00:00

  • Effect of cholecystectomy on gastric and esophageal bile reflux in patients with upper gastrointestinal symptoms.

    abstract::Epidemiologic data have shown that cholecystectomy is associated with a moderately increased risk of esophageal adenocarcinoma. The study objective was to evaluate the role of refluxed bile. A total of 696 patients with upper gastrointestinal symptoms were included in the study, of whom 55 had a history of cholecystec...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-007-9989-8

    authors: Fein M,Bueter M,Sailer M,Fuchs KH

    更新日期:2008-05-01 00:00:00

  • Randomized, single-blind, placebo-controlled multicenter trial to compare the efficacy and safety of metronidazole and satranidazole in patients with amebic liver abscess.

    abstract::The aims of our randomized, single-blind trial involving 49 patients were to study the efficacy, side effects, and tolerance of metronidazole and satranidazole in patients of amebic liver abscess. Twenty-five patients received metronidazole (800 mg TID) and 24 received satranidazole (300 mg TID with placebo at mealtim...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s10620-006-9111-7

    authors: Muzaffar J,Madan K,Sharma MP,Kar P

    更新日期:2006-12-01 00:00:00

  • Effects of graded amounts of intragastric calcium on acid secretion, gastrin release, and gastric emptying in normal and duodenal ulcer subjects.

    abstract::We studied effects of graded concentrations of intragastric calcium on acid secretion, residual gastric volume, and serum gastrin and calcium levels. Intragastric titration was performed with solutions of isotonic mannitol or mannitol plus 2.5, 6, 16, 39, and 97 mM CaCl(2) in 10 normal and eight duodenal ulcer subject...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02430525

    authors: Barclay G,Maxwell V,Grossman MI,Solomon TE

    更新日期:1983-05-01 00:00:00

  • Hepatitis A, hepatitis B, and combination hepatitis vaccines for immunoprophylaxis: an update.

    abstract::Since the publication of the last extensive review of hepatitis vaccines, use of inactivated hepatitis A vaccines has been extended to high-risk regions of the United States and specific patient groups, such as those with chronic liver disease, and use of the recombinant hepatitis B vaccines has been recommended for o...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1023/a:1015397807278

    authors: Koff RS

    更新日期:2002-06-01 00:00:00

  • Eosinophilic gastroenteritis: a review.

    abstract::Eosinophilic gastroenteritis is a rare benign disease characterized by tissue eosinophilic infiltration that may involve several digestive tract layers. Also known as allergic, or eosinophilic allergic, gastroenteropathy, it usually involves the stomach and small intestine: rarely the colon. It may or may not be accom...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-005-9011-2

    authors: Méndez-Sánchez N,Chávez-Tapia NC,Vazquez-Elizondo G,Uribe M

    更新日期:2007-11-01 00:00:00

  • Modafinil in the treatment of debilitating fatigue in primary biliary cirrhosis: a clinical experience.

    abstract::Modafinil may be a potentially effective treatment for primary biliary cirrhosis (PBC)-related fatigue. About 42 patients were given a 3-day trial of 100-200 mg modafinil. Response was defined as increased energy, decreased somnolence and sleep requirements, and improved daily function. Patients with positive response...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-008-0613-3

    authors: Ian Gan S,de Jongh M,Kaplan MM

    更新日期:2009-10-01 00:00:00

  • Periampullary Diverticula and ERCP Outcomes: A Systematic Review and Meta-Analysis.

    abstract:INTRODUCTION:Periampullary diverticulum (PAD) is most often asymptomatically found in elderly population. ERCP in the presence of PAD is technically challenging since the location and orientation of the ampulla could be altered. Various studies have reported differing results on the technical success and safety outcome...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,meta分析

    doi:10.1007/s10620-018-5314-y

    authors: Jayaraj M,Mohan BP,Dhindsa BS,Mashiana HS,Radhakrishnan G,Dhir V,Trindade AJ,Adler DG

    更新日期:2019-05-01 00:00:00

  • Chronic hepatitis C without anti-hepatitis C antibodies by second-generation assay. A clinicopathologic study and demonstration of the usefulness of a third-generation assay.

    abstract::To study the clinicopathologic features of hepatitis C viremic patients negative for hepatitis C antibodies (anti-HCV) by current second-generation assay, we categorized 139 consecutive histologically verified patients with chronic non-A, non-B hepatitis into three groups: 121 (87%) were positive for second-generation...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02208599

    authors: Kao JH,Lai MY,Hwang YT,Yang PM,Chen PJ,Sheu JC,Wang TH,Hsu HC,Chen DS

    更新日期:1996-01-01 00:00:00

  • Mucosal addressin cell adhesion molecule (MAdCAM-1) expression is upregulated in the cirrhotic liver and immunolocalises to the peribiliary plexus and lymphoid aggregates.

    abstract:BACKGROUND:Enhanced cell expression of MAdCAM-1 is critical in tissue recruitment of lymphocytes in response to stimuli expressing the α4β7 integrin. MAdCAM-1 is well characterized in gut mucosa with emerging evidence of hepatic expression. AIMS:(i) Compare quantitative/semi-quantitatively MAdCAM-1 expression in relat...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-013-2755-1

    authors: Ala A,Brown D,Khan K,Standish R,Odin JA,Fiel MI,Schiano TD,Hillan KJ,Rahman SA,Hodgson HJ,Dhillon AP

    更新日期:2013-09-01 00:00:00

  • Role of the jejunum versus ileum on intestinal gas dynamics during a balanced meal in healthy subjects.

    abstract::Under physiological conditions, the human gut adapts intestinal gas propulsion and evacuation to prevent intestinal gaseous complaints In this study we aimed to determine influences of the jejunum versus ileum on intestinal gas dynamics during a balanced meal. Paired studies were randomly performed with seven women an...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-006-9344-5

    authors: Harder H,Hernando-Harder AC,Franke A,Krammer HJ,Singer MV

    更新日期:2006-05-01 00:00:00