During thioacetamide-induced acute liver failure, the proliferative response of hepatocytes to thyroid hormone is maintained, indicating a potential therapeutic approach to toxin-induced liver disease.

abstract：BACKGROUND:The principle of treating-to-target has been successfully applied to many diseases with significant improvement in patient care and as a useful guidance for healthcare providers. Appreciation of the central role for arterial vasodilatation in the pathogenesis of hepatorenal syndrome (HRS) has led to routine ...

journal_title：Digestive diseases and sciences

authors： Cai CX,Maddukuri G,Jaipaul N,Zhang Z

更新日期：2015-05-01 00:00:00

abstract：:The aim of this study was to investigate the effect of intestinal electrical stimulation on small intestinal dysrhythmia and motion sickness-like symptoms induced by vasopressin. Female dogs chronically implanted with two pairs of electrodes on jejunum serosa were used in a four-session study. Saline and vasopressin w...

journal_title：Digestive diseases and sciences

authors： Liu J,Wang L,Chen JD

更新日期：2004-05-01 00:00:00

abstract：:Ninety-one patients with idiopathic constipation had segmental colonic transit studied with radiopaque markers using a new simplified technique to determine frequency and type of colonic transit time (CTT) abnormalities and to determine the utility of this test in planning therapy. Colonic transit studies defined four...

journal_title：Digestive diseases and sciences

authors： Chaussade S,Khyari A,Roche H,Garret M,Gaudric M,Couturier D,Guerre J

更新日期：1989-08-01 00:00:00

abstract：:Using conventional statistical analysis and multiple regression analysis, we investigated the viral and host factors that influence the response to recombinant interferon-alpha 2a therapy in patients with chronic hepatitis C. A total of 36 patients was randomly assigned to three administration schedules, 12 patients i...

journal_title：Digestive diseases and sciences

authors： Matsumoto A,Tanaka E,Suzuki T,Ogata H,Kiyosawa K

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Safety-net hospitals are enriched in ethnic minorities and provide opportunities for high-impact hepatitis B virus (HBV) screening. AIM:We aim to evaluate the impact of a pilot program integrating HBV screening into outpatient endoscopy among urban safety-net populations. METHODS:From July 2015 to May 2017...

journal_title：Digestive diseases and sciences

authors： Campbell B,Lopez A,Liu B,Bhuket T,Wong RJ

更新日期：2018-01-01 00:00:00

abstract：:An intussusception of the small intestine in association with a long tube usually occurs in the vicinity of the mercury-filled bag and can be visualized radiographically by instilling barium directly into the tube. On rare occasions, an intussusception develops in the proximal jejunum and is difficult to recognize. We...

journal_title：Digestive diseases and sciences

authors： Peskin SR,Langevin RE Jr,Banks PA

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous dilatation of the common bile duct and pancreatic duct, "double-duct sign" (DDS), is an ominous finding concerning for pancreaticobiliary malignancy. Little evidence exists to guide the initial evaluation and subsequent follow-up for patients with DDS in the absence of jaundice or focal ...

journal_title：Digestive diseases and sciences

authors： Cohen J,Sawhney MS,Pleskow DK,Chuttani R,Patel NJ,Sheridan J,Berzin TM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND AIM:There is no consensus regarding the benefit of eradicating Helicobacter pylori (H. pylori) infection in patients with functional dyspepsia (FD). We intended to compare the symptom response to H. pylori eradication in FD patients in presence or absence of microscopic duodenitis (MD). METHODS:Patients...

journal_title：Digestive diseases and sciences

authors： Mirbagheri SS,Mirbagheri SA,Nabavizadeh B,Entezari P,Ostovaneh MR,Hosseini SM,Rakhshani N,Safa H

更新日期：2015-01-01 00:00:00

abstract：:The growth of the human gastrinoma model (PT) in athymic nude mice is stimulated by bombesin (BBS), an amphibian peptide homologous to both human gastrin-releasing peptide (GRP) and neuromedin B (NMB). The mechanism is not known, and a potent and specific GRP-R antagonist BIM26226, which has low affinity for NMB-R, wa...

journal_title：Digestive diseases and sciences

authors： Chu KU,Ishizuka J,Battey JF,Uchida T,Beauchamp RD,Townsend CM Jr,Thompson JC

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

journal_title：Digestive diseases and sciences

authors： Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Notch signaling is required for the maintenance of intestinal epithelial proliferation. Dysfunction of this signaling pathway is associated with the loss of proliferated crypt epithelial cells. AIM:The aim of this study was to investigate the role of Notch signaling in small bowel resection (SBR)-associated...

journal_title：Digestive diseases and sciences

authors： Chen G,Sun L,Yu M,Meng D,Wang W,Yang Y,Yang H

更新日期：2013-09-01 00:00:00

abstract：:In a subset of patients with gastroesophageal reflux disease (GERD), symptoms persist in spite of proton pump inhibitor (PPI) therapy. Endoscopic gastroplication (EG) was reported to provide a novel therapeutic option in GERD. To evaluate symptomatic and objective outcome of EG in PPI refractory GERD, consecutive GERD...

journal_title：Digestive diseases and sciences

authors： Arts J,Lerut T,Rutgeerts P,Sifrim D,Janssens J,Tack J

更新日期：2005-02-01 00:00:00

abstract：:The use of total parenteral nutrition and enteral nutrition in inflammatory bowel disease has become commonplace. Except for well-documented improvements in nutritional parameters, the efficacy of these treatments for primary therapy or for complications remains largely unproven. ...

journal_title：Digestive diseases and sciences

authors： Whittaker JS

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:We previously reported that preoperative chemolipiodolization of the whole liver is effective for reducing the incidence of postoperative recurrence and prolonging survival in patients with resectable hepatocellular carcinoma (HCC). The present randomized controlled trial was performed to evaluate the influe...

journal_title：Digestive diseases and sciences

authors： Kaibori M,Tanigawa N,Kariya S,Ikeda H,Nakahashi Y,Hirohara J,Koreeda C,Seki T,Sawada S,Okazaki K,Kwon AH

更新日期：2012-05-01 00:00:00

abstract：:Sodium butyrate is a well-recognized differentiating agent inducing alkaline phosphatase activity, one of the epithelial differentiation markers. When IEC6 cells, a nontransformed, small intestinal epithelial cell line, were cultured with butyrate, this substrate induced alkaline phosphate activity in a time- and dose...

journal_title：Digestive diseases and sciences

authors： Fukushima K,Sasaki I,Hasegawa H,Takahashi K,Naito H,Funayama Y,Matsuno S

更新日期：1998-05-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to investigate and compare the specificity, sensitivity, and area under curve (AUC) of the lactulose/mannitol ratio, lactulose/creatinine ratio, and lactulose recovery and their diagnostic value for intestinal permeability assessment within the absorption lactulose/mannitol (L/M...

journal_title：Digestive diseases and sciences

authors： Dastych M,Dastych M Jr,Novotná H,Cíhalová J

更新日期：2008-10-01 00:00:00

abstract：:The efficacy of tiotidine, a new H2-receptor antagonist, in reducing nocturnal acid secretion of duodenal ulcer patients (N = 12, ages 21-60 years) was investigated. Different doses of tiotidine, 25, 50, 100, and 150 mg or placebo, were given as a single oral dose and acid secretion collected overnight. Tiotidine prod...

journal_title：Digestive diseases and sciences

authors： Valenzuela JE,Strecker RB,Douglas AP

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The incidence of Clostridium difficile infection is increasing in the United States. The aim of our investigation is to compare short-term and long-term outcomes of patients admitted with an ulcerative colitis (UC) flare and co-existent C. difficile infection to those of non-infected patients. METHODS:A his...

journal_title：Digestive diseases and sciences

authors： Jodorkovsky D,Young Y,Abreu MT

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Data on cyclic vomiting syndrome (CVS) are limited to studies from tertiary care centers. There is a paucity of information about CVS on a national scale. AIM:To study the clinical characteristics, comorbidities, and hospital outcomes in patients hospitalized with CVS using a nationwide database. METHODS:W...

journal_title：Digestive diseases and sciences

authors： Bhandari S,Venkatesan T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To prospectively evaluate the frequency of upper gastrointestinal symptoms and associated disorders in morbidly obese patients with endoscopy and histology prior to their gastric bypass surgery in comparison with age- and sex-matched nonobese control subjects. METHODS:All patients who were scheduled to under...

journal_title：Digestive diseases and sciences

authors： Dutta SK,Arora M,Kireet A,Bashandy H,Gandsas A

更新日期：2009-06-01 00:00:00

abstract：:Nine patients with concurrent myelodysplastic syndrome (MDS) and inflammatory bowel disease (IBD) were examined. Median age at diagnosis of these patients was similar to the usual age of patients at diagnosis of IBD only. There was a strong predominance of Crohn's disease (seven of nine cases), with an unusually high ...

journal_title：Digestive diseases and sciences

authors： Wang Z,Zhou Y,Liu Y

更新日期：2008-07-01 00:00:00

abstract：:Technological developments have greatly promoted interest in the use of computer systems for recording findings and images at endoscopy and creating databases. The aim of this study was to develop a comprehensive WHO-approved code system for gastrointestinal endoscopic terminology. The International Classification of ...

journal_title：Digestive diseases and sciences

authors： Groenen MJ,Hirs W,Becker H,Kuipers EJ,Van Berge Henegouwen GP,Fockens P,Ouwendijk RJ

更新日期：2007-04-01 00:00:00

abstract：:The initiating mechanisms involved in colonic injury are currently unknown. The goal of the current study was to examine the role of the inflammatory mediators reactive oxygen metabolites and proteases in an ex vivo model of selective epithelial permeability. Rats were prepared with exteriorized colonic chambers to wh...

journal_title：Digestive diseases and sciences

authors： Berin MC,Buell MG

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Partially covered metal stents (PCMS) have been increasingly used for both malignant and benign biliary indications. This study reports their complications and subsequent management. METHODS:Over 5 years, all patients receiving biliary PCMS were followed prospectively until stent-related dysfunction or deat...

journal_title：Digestive diseases and sciences

authors： Ho H,Mahajan A,Gosain S,Jain A,Brock A,Rehan ME,Ellen K,Shami VM,Kahaleh M

更新日期：2010-02-01 00:00:00

abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

journal_title：Digestive diseases and sciences

authors： Eaves ER,Hansky J

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is an established causal factor for non-cardia gastric cancer. H. pylori negative gastric cancer prevalence among US patients is unclear. METHODS:This retrospective cohort study examined H. pylori prevalence among consecutive patients with incident non-cardia gastric adenocarci...

journal_title：Digestive diseases and sciences

authors： Nguyen TH,Mallepally N,Hammad T,Liu Y,Thrift AP,El-Serag HB,Tan MC

更新日期：2020-08-01 00:00:00

abstract：:It is unknown whether demography, gallbladder function, or the radiographic appearance of gallstones predispose them to cause symptoms. We investigated these features in a consecutive series of 260 patients with newly diagnosed, uncomplicated gallstone disease, of whom 146 had experienced biliary pain and 114 were asy...

journal_title：Digestive diseases and sciences

authors： Ros E,Valderrama R,Bru C,Bianchi L,Terés J

更新日期：1994-08-01 00:00:00

abstract：:We evaluated the alveolar-arterial oxygen difference (deltaA-a) and the ratio between PaO2 and the fractional concentration of inspired oxygen (P/F) in acute pancreatitis. Eleven patients had mild uncomplicated disease, six showed acute abdominal fluid collections, six had acute abdominal collections and asymptomatic ...

journal_title：Digestive diseases and sciences

authors： Salomone T,Tosi P,Di Battista N,Binetti N,Raiti C,Tomassetti P,Migliori M,Gullo L

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Controlled attenuation parameter (CAP) has been developed to estimate the extent of hepatic steatosis. AIMS:The purpose was to evaluate the usefulness of CAP in assessing hepatic steatosis and its change using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as reference standard. METHODS:...

journal_title：Digestive diseases and sciences

authors： Wang JH,Ou HY,Yen YH,Chen CH,Lu SN

更新日期：2020-05-01 00:00:00

abstract：:Forty-nine Japanese patients were enrolled in a randomized, placebo-controlled, double-blind trial of alpha-interferon for chronic non-A, non-B hepatitis: 24 patients received 3 million units of recombinant human alpha alpha-interferon (alpha-2a) thrice weekly for eight weeks, and 25 patients received placebo in a sim...

journal_title：Digestive diseases and sciences

authors： Omata M,Ito Y,Yokosuka O,Imazeki F,Tagawa M,Takano S,Hosoda K,Tada M,Ohto M,Ito K

更新日期：1991-09-01 00:00:00