Surgical bypass versus endoscopic stenting for malignant gastroduodenal obstruction: a decision analysis.

abstract：:Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on...

journal_title：Digestive diseases and sciences

authors： Yang AM,Shih SC,Chu CH,Wang TE,Yang WS

更新日期：2010-03-01 00:00:00

abstract：:Published clinical trials (N = 56) of antisecretory drugs in the treatment of benign gastric ulcer were reviewed. Composite healing rates for various drug regimens were calculated using a method previously described for duodenal ulcer. Healing rates were compared with data on suppression of intragastric acidity to see...

journal_title：Digestive diseases and sciences

authors： Howden CW,Jones DB,Peace KE,Burget DW,Hunt RH

更新日期：1988-05-01 00:00:00

abstract：:In Japanese healthy CYP2C19 extensive metabolizers, rabeprazole 10 mg shows a faster onset of action and stronger inhibition of acid secretion than does omeprazole 20 mg on the first 3 days of administration. We evaluated gastric ulcer improvement after 1 week's treatment with rabeprazole or omeprazole in relation to ...

journal_title：Digestive diseases and sciences

authors： Ando T,Ishikawa T,Kokura S,Naito Y,Yoshida N,Yoshikawa T

更新日期：2008-04-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection is a major etiology of chronic liver disease worldwide. In the past decade, nonalcoholic fatty liver disease (NAFLD) has emerged as a common liver disorder in general population. Accordingly, the patient number of chronic hepatitis B (CHB) concomitant with NAFLD grows rapidly. The pre...

journal_title：Digestive diseases and sciences

authors： Lin CW,Huang XL,Liu HL,Wang Y

更新日期：2015-12-01 00:00:00

abstract：:The synthetic substrate cholyl-PABA, developed by conjugating cholic acid with paraaminobenzoic acid, is hydrolyzed by the bacterial enzyme cholyl hydrolase to release free PABA. This study aimed to evaluate whether quantitating urinary excretion of PABA after oral administration of cholyl-PABA can detect small intest...

journal_title：Digestive diseases and sciences

authors： Bardhan PK,Feger A,Kogon M,Muller J,Gillessen D,Beglinger C,Gyr N

更新日期：2000-03-01 00:00:00

abstract：INTRODUCTION:The impact of antithrombotic treatment on the findings of small-bowel capsule endoscopy for patients with obscure gastrointestinal bleeding remains contentious. We aimed to determine the effect of these agents on small-bowel video capsule endoscopy positive findings. METHODS:MEDLINE, Cochrane Library, and...

journal_title：Digestive diseases and sciences

authors： Tziatzios G,Gkolfakis P,Papanikolaou IS,Triantafyllou K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Adenosine deaminase acting on RNA 1 (ADAR1) is known to mediate deamination of adenosine-to-inosine through binding to double-stranded RNA, the phenomenon known as RNA editing. Currently, the function of ADAR1 in gastric cancer is unclear. AIMS:This study was aimed at investigating RNA editing-dependent and...

journal_title：Digestive diseases and sciences

authors： Cho CJ,Jung J,Jiang L,Lee EJ,Kim DS,Kim BS,Kim HS,Jung HY,Song HJ,Hwang SW,Park Y,Jung MK,Pack CG,Myung SJ,Chang S

更新日期：2018-07-01 00:00:00

abstract：:Free radical damage in reflux esophagitis of rats induced by 24-hr duodenojejunal ligation was studied. Oxygen free radicals were selectively blocked. Groups were: sham operation, reflux, reflux + superoxide dismutase (SOD), catalase, dimethylthiourea, allopurinol, and inactivated SOD or inactivated catalase alone or ...

journal_title：Digestive diseases and sciences

authors： Wetscher GJ,Hinder PR,Bagchi D,Perdikis G,Redmond EJ,Glaser K,Adrian TE,Hinder RA

更新日期：1995-06-01 00:00:00

abstract：:The aim of this study was to compare alcohol and smoking as risk factors in the development of chronic pancreatitis and pancreatic cancer. We considered only male subjects: (1) 630 patients with chronic pancreatitis who developed 12 pancreatic and 47 extrapancreatic cancers; (2) 69 patients with histologically well do...

journal_title：Digestive diseases and sciences

authors： Talamini G,Bassi C,Falconi M,Sartori N,Salvia R,Rigo L,Castagnini A,Di Francesco V,Frulloni L,Bovo P,Vaona B,Angelini G,Vantini I,Cavallini G,Pederzoli P

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Sorafenib, a drug that inhibits Raf serine/threonine kinases mediating cell proliferation and receptor tyrosine kinases involved in angiogenesis, is approved for treatment of advanced hepatocellular carcinoma. AIMS:To explore the efficacy and safety of sorafenib for treating advanced HCC, and to identify cl...

journal_title：Digestive diseases and sciences

authors： Xie B,Wang DH,Spechler SJ

更新日期：2012-05-01 00:00:00

abstract：:The present paper evaluates the efficiency of Nissen fundoplication as an antireflux technique in a series of 51 patients with different grades of esophagitis. Follow-up time averaged 6.6 years. The evaluation includes a clinical assessment, endoscopic study, and 24-hr pH monitoring. The results reveal an acceptable r...

journal_title：Digestive diseases and sciences

authors： Martinez de Haro LF,Ortiz A,Parrilla P,Garcia Marcilla JA,Aguayo JL,Morales G

更新日期：1992-04-01 00:00:00

abstract：:The effect of inhibition of acid secretion on parietal cell morphology and the concentration of H,K-ATPase alpha-subunit protein was determined by electron microscopy and western blotting. Omeprazole or famotidine alone or in combination were used. Control animals showed a morphological stimulation index (0 = resting,...

journal_title：Digestive diseases and sciences

authors： Scott DR,Besancon M,Sachs G,Helander H

更新日期：1994-10-01 00:00:00

abstract：:Abnormalities in the gastric pacemaker potentials occur in patients with impaired gastric emptying. It is unclear if treatment effects the underlying rhythm or if normalization of dysrhythmias is important. We examined the effect of cisapride using surface electrogastrograms and radionuclide gastric emptying studies o...

journal_title：Digestive diseases and sciences

authors： Rothstein RD,Alavi A,Reynolds JC

更新日期：1993-08-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：:We have studied pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells. Monolayers were formed after approximately 48 hr. Pepsinogen synthesis was studied by adding 14C-labeled amino acids to the culture medium. Basal secretion of de novo synthesized pepsinogen after 4 hr was 4 ...

journal_title：Digestive diseases and sciences

authors： Defize J,Hunt RH

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Peyer's patches (PPs), which are covered by specialized follicle-associated epithelium (FAE) including M cells, play a central role in immune induction in the gastrointestinal tract. This study is to investigate a new molecule to characterize PPs. METHODS:We generated a monoclonal antibody (mAb 10-15-3-3) t...

journal_title：Digestive diseases and sciences

authors： Tokuhara D,Nochi T,Matsumura A,Mejima M,Takahashi Y,Kurokawa S,Kiyono H,Yuki Y

更新日期：2014-11-01 00:00:00

abstract：:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by...

journal_title：Digestive diseases and sciences

authors： Maes BD,Ghoos YF,Rutgeerts PJ,Hiele MI,Geypens B,Vantrappen G

更新日期：1994-12-01 00:00:00

abstract：:The effects of cisapride on upper gut motility were studied in seven healthy volunteers by means of a novel intraluminal electromyographic technique in a placebo-controlled study. In the interdigestive state, cisapride (10 mg intravenous bolus injection) markedly increased the number of spike bursts. The most obvious ...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1988-12-01 00:00:00

abstract：:Many physiological factors can alter gastric emptying, and the role of gastric emptying in functional dyspepsia is controversial. The aim of this study was to assess the effects of different factors (age, sex, the degree of dyspeptic and irritable bowel symptoms, lactase deficiency, smoking habits, the use of antiinfl...

journal_title：Digestive diseases and sciences

authors： Koskenpato J,Kairemo K,Korppi-Tommola T,Färkkilä M

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Minimal hepatic encephalopathy is the mildest form of the spectrum of hepatic encephalopathy (HE) that impairs health-related quality of life. We assessed (1) the usefulness of psychometric hepatic encephalopathy score and critical flicker frequency for the diagnosis of minimal hepatic encephalopath...

journal_title：Digestive diseases and sciences

authors： Dhiman RK,Kurmi R,Thumburu KK,Venkataramarao SH,Agarwal R,Duseja A,Chawla Y

更新日期：2010-08-01 00:00:00

abstract：:We have studied three patients with chronic HBV infection who had a superimposed bout of type A hepatitis. The patients recovered uneventfully without observing a change in their clinical course afterwards. In one patient we observed transient disappearance of DNA polymerase during type A hepatitis; we have postulated...

journal_title：Digestive diseases and sciences

authors： Conteas C,Kao H,Rakela J,Weliky B

更新日期：1983-08-01 00:00:00

abstract：:The effect of nutrients on small intestinal motility is controversial. Our aim was to analyze the effect of intraduodenal infusion of mixtures of nutrients of increasing caloric load, on intestinal motility. Studies were performed in dogs with a duodenal cannula. Isosmolar infusions of saline, 0.5, 2, and 4 kcal/min w...

journal_title：Digestive diseases and sciences

authors： Defilippi C

更新日期：2003-08-01 00:00:00

abstract：:In addition to regulating blood pressure and body fluid homeostasis, the renin-angiotensin system (RAS) is also involved in hepatic fibrogenesis. We aimed to investigate the effect of losartan, an angiotensin II (Ang II) antagonist, on CCl4-induced hepatic fibrosis in rats. Hepatic fibrosis was induced by a subcutaneo...

journal_title：Digestive diseases and sciences

authors： Wei YH,Jun L,Qiang CJ

更新日期：2004-10-01 00:00:00

abstract：:Patients with symptomatic cholelithiasis who represent higher than normal surgical risks may be the most suitable candidates for medical dissolution of gallstones. Chenodeoxycholic acid was given to 97 patients in a dosage of 15 mg/kg of body weight per day for a period of two years. Complete gallstone dissolution occ...

journal_title：Digestive diseases and sciences

authors： Tangedahl T,Carey WD,Ferguson DR,Forsythe S,Williams M,Paradis K,Hightower NC

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Estradiol-17β-D-glucuronide (E17G) induces cholestasis in vivo, endocytic internalization of the canalicular transporters multidrug resistance-associated protein 2 (Abcc2) and bile salt export pump (Abcb11) being a key pathomechanism. Cyclic AMP (cAMP) prevents cholestasis by targeting these transporters bac...

journal_title：Digestive diseases and sciences

authors： Zucchetti AE,Barosso IR,Boaglio AC,Luquita MG,Roma MG,Crocenzi FA,Sánchez Pozzi EJ

更新日期：2013-06-01 00:00:00

abstract：:The aim of the present study was to investigate the antioxidative effects of water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), on ischemia-reperfusion (I/R) -induced gastric mucosal injury in rats. Gastric ischemia was induced by applying a small clamp to the c...

journal_title：Digestive diseases and sciences

authors： Ichikawa H,Yoshida N,Takano H,Ishikawa T,Handa O,Takagi T,Naito Y,Murase H,Yoshikawa T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Although a genetic component has been identified as a risk factor for developing inflammatory bowel disease, there is evidence that dietary factors also play a role in the development of this disease. AIMS:The aim of this study was to determine the effects of feeding a red meat diet with and without resista...

journal_title：Digestive diseases and sciences

authors： Le Leu RK,Young GP,Hu Y,Winter J,Conlon MA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The role of cannabinoids in gastrointestinal diseases is controversial and of great interest, yet their use in patients has not been critically examined. AIM:To determine the prevalence and effects of cannabis abuse on healthcare utilization, as measured by emergency department (ED) visits, in a large, tert...

journal_title：Digestive diseases and sciences

authors： Gubatan J,Staller K,Barshop K,Kuo B

更新日期：2016-07-01 00:00:00

abstract：:The aim of this study was to review the impact of infliximab therapy on children with treatment-resistant Crohn's disease. Treatment resistance was defined as clinically active disease despite >4 months of immunosuppressive therapy. The outcome variables were time to first remission, duration of remission and the need...

journal_title：Digestive diseases and sciences

authors： Afzal NA,Ozzard A,Keady S,Thomson M,Murch S,Heuschkel R

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity is a known risk factor for diverticulitis. Our objective was to examine the less investigated impact of morbid obesity (MO) on admissions and clinical course of diverticulitis in a US representative database. METHODS:We retrospectively queried the 2010-2014 Nationwide Readmission Database t...

journal_title：Digestive diseases and sciences

authors： Patel K,Krishna SG,Porter K,Stanich PP,Mumtaz K,Conwell DL,Clinton SK,Hussan H

更新日期：2020-09-01 00:00:00