[*C]octanoic acid breath test to measure gastric emptying rate of solids.

Abstract:

:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by simultaneous radioscintigraphic and breath test measurements. Nine healthy volunteers were studied after intravenous administration of 200 mg erythromycin and peroral administration of 30 mg propantheline, respectively. Erythromycin significantly enhanced gastric emptying, while propantheline significantly reduced gastric emptying rates. We conclude that the [*C]octanoic breath test is a promising and reliable test for measuring the gastric emptying rate of solids.

journal_name

Dig Dis Sci

authors

Maes BD,Ghoos YF,Rutgeerts PJ,Hiele MI,Geypens B,Vantrappen G

doi

10.1007/BF02300385

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

104S-106S

issue

12 Suppl

eissn

0163-2116

issn

1573-2568

journal_volume

39

pub_type

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