Abstract：
:The effect of nutrients on small intestinal motility is controversial. Our aim was to analyze the effect of intraduodenal infusion of mixtures of nutrients of increasing caloric load, on intestinal motility. Studies were performed in dogs with a duodenal cannula. Isosmolar infusions of saline, 0.5, 2, and 4 kcal/min were performed and motility recorded by means of infused catheters. Nonstatistically significant differences were observed between frequency of contractions during infusion of 0.5 (4.1 +/- 1.6 cpm) and 2 kcal/min (5.3 +/- 1.5 cpm) compared to control (4.3 +/- 1.9 cpm). With 4 kcal/min a significant decrease of frequency (2.7 +/- 0.9 cpm) was observed. A similar finding was observed for amplitude of contrations. With 0.5 kcal/min fasting cyclic activity was still present, but the numbers of phase III were significantly reduced, associated with an increased duration of phase II. With higher caloric loads cyclic fasting activity was replaced by marked variations of frequency, following a cyclic pattern. A lower threshold for mechanisms switching the fasting to fed state was observed, compared to those controlling frequency and amplitude.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Defilippi Cdoi
10.1023/a:1024799303676subject
Has Abstractpub_date
2003-08-01 00:00:00pages
1482-6issue
8eissn
0163-2116issn
1573-2568journal_volume
48pub_type
杂志文章abstract：:For biotherapeutic agents, there is a lack of information on dose-response relationships and mechanism of action. The present study was designed to address these issues for Saccharomyces boulardii using the rat model of castor oil-induced diarrhea. A single dose of Saccharomyces boulardii at 12 x 10(10) CFU/kg of viab...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1022801228938
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND AND AIMS:The impact of obesity on survival following liver transplantation is unclear, and existing studies report conflicting results. Our current study aims to further delineate the impact of obesity using population-based registry data from the USA. METHODS:All US adult liver transplant recipients from 2...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3469-8
更新日期：2015-04-01 00:00:00
abstract：:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, s...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/BF01312467
更新日期：1987-12-01 00:00:00
abstract：:Theoretically, relative distal common bile duct obstruction due to sphincter of Oddi dysfunction may be a cause of poor gallbladder evacuation observed on quantitative cholescintigraphy. In this study, the relationship of sphincter of Oddi dysfunction to the gallbladder ejection fraction by quantitative cholescintigra...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02090199
更新日期：1994-02-01 00:00:00
abstract：:The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial he...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-9595-1
更新日期：2007-05-01 00:00:00
abstract：:Although the pathogenic mechanisms of inflammatory bowel diseases are not fully understood, colonic microbiota may affect the induction of colonic inflammation, and some probiotics and prebiotics have been reported to suppress colitis. The inhibitory effects of brown rice fermented by Aspergillus oryzae (FBRA), a fibe...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-007-0063-3
更新日期：2008-06-01 00:00:00
abstract：:Orocecal transit time was determined by the lactulose hydrogen breath test in nine healthy volunteers after administration of placebo, loperamide (16 mg per os), and loperamide (16 mg per os) followed by oral naloxone at doses of 16 and 32 mg. The four tests were performed in double-blind conditions and in random sequ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01296704
更新日期：1987-08-01 00:00:00
abstract：BACKGROUND:Small bowel mass lesions (SBML) are a relatively common cause of obscure gastrointestinal bleeding (OGIB). Their detection has been limited by the inability to endoscopically examine the entire small intestine. This has changed with the introduction of capsule endoscopy (CE) and double balloon enteroscopy (D...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究
doi：10.1007/s10620-007-0110-0
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The performance characteristics of colonic sensation and motility measurements are unclear. AIM:To compare left colon compliance, tone, and sensation in males and females and to evaluate inter and intra-individual coefficients of variation (COV) in these measurements. METHODS:Data were acquired using stand...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-009-0772-x
更新日期：2010-03-01 00:00:00
abstract：:Autoimmune hepatitis has two major variant phenotypes in which the features of classical disease are co-mingled with those of primary biliary cirrhosis or primary sclerosing cholangitis. These overlap syndromes lack codified diagnostic criteria, established pathogenic mechanisms, and confident management strategies. T...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-012-2367-1
更新日期：2013-02-01 00:00:00
abstract：:Transient delayed gastric emptying is reported as a frequent complication following pancreas-preserving pancreaticoduodenectomy (PPW). We placed serosal electrodes on the stomach of a patient undergoing PPW. Myoelectric recordings were obtained postoperatively and correlated with simultaneous radionuclide liquid gastr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536411
更新日期：1990-10-01 00:00:00
abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308344
更新日期：1992-01-01 00:00:00
abstract：:Solitary rectal ulcer syndrome (SRUS) is sufficiently uncommon that the clinician or general pathologist may lack familiarity with the disorder and may confuse it with other inflammatory bowel diseases. To evaluate the role of collagen staining in facilitating the differential diagnosis of SRUS, an initial open review...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536986
更新日期：1988-11-01 00:00:00
abstract：:Cyclic vomiting syndrome is a disorder characterized by recurrent episodes of nausea and vomiting with complete resolution of symptoms between attacks. Nitric oxide plays a critical role in regulating several components of gastrointestinal mucosal defense and injury. Interleukin-6 has a wide variety of actions in the ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1010712703685
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:DNA methylation mainly affects tumor suppressor genes in the development of hepatocellular carcinoma (HCC). However, sera methylation of specific genes in hepatitis B virus (HBV)-related HCC remains unknown. AIMS:The purpose of this study was to identify methylation frequencies of sera E-cadherin (CDH1), DN...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-015-3975-3
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5018-3
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:The impact of prior anti-TNF use on "real-life" outcomes of adalimumab therapy in ulcerative colitis (UC) is not well known. AIM:To compare the influence of prior anti-TNF use on the outcomes of adalimumab maintenance treatment in UC patients. We also assessed the effectiveness of adalimumab dose escalation...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究
doi：10.1007/s10620-016-4398-5
更新日期：2017-02-01 00:00:00
abstract：:A retrospective multicenter analysis of 652 patients with chronic hepatitis C who have been treated with interferon (IFN) was performed to assess the effects of IFN on the clinical course and development of HCC. During a mean follow-up of 54.8 months, hepatocellular carcinoma (HCC) developed in 7.0% of the patients. T...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究
doi：10.1023/a:1013244326874
更新日期：2002-01-01 00:00:00
abstract：:An association between hypothermia and gastric ulceration has been reported in rats in cervical cord section and in restraint models. The present study was designed to determine this relationship in cervical and in lumbar cord sectioned Sprague-Dawley rats. Ambient temperatures were varied by placing the sectioned ani...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01307976
更新日期：1981-01-01 00:00:00
abstract：:Somatostatin analog SMS 201-995 causes a dose-related suppression of the release and/or action of several gastrointestinal hormones and impairs several anterior pituitary functions. Some patients with illness involving abnormal hormonal activity have responded to treatment with SMS 201-995, including resolution of sev...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296623
更新日期：1991-12-01 00:00:00
abstract：BACKGROUND:Intestinal failure is the most critical complication of Crohn's disease. Intestinal failure requires home parenteral nutrition, which worsens the quality of life of the patients and sometimes causes life-threatening complications. AIMS:The purpose of this study was to investigate the incidence and risk fact...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05553-2
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:The receptor for formylated peptides, formyl peptide receptor 1 (FPR1), potently activates and serves as a chemoattractant receptor for neutrophils. AIM:Given the abundance of neutrophils in the inflamed colon, our aim was to determine if the FPR1 mediates colonic neutrophil migration, using the dextran sod...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2082-y
更新日期：2012-07-01 00:00:00
abstract：:The effects of sennosides on colonic myoelectrical activity were investigated in man. Spiking activity of the left and sigmoid colons was continuously recorded in seven constipated patients during two sessions from 5:00 PM to 9:00 AM. Each patient received orally at 7:00 PM on two consecutive days 30 mg of sennosides ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01536053
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:Colorectal cancer (CRC) screening is cost-effective and prevents death from CRC if used appropriately. Physicians do not recommend CRC screening according to guidelines. Physician-related factors associated with CRC screening knowledge are unknown. AIMS:We tested the accuracy of CRC screening knowledge in a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5339-2
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:The overwhelming majority of reported duodenal and colonic SEMS placements in the literature have used the 0.035″ guidewire almost to the exclusion of guidewires of other diameters. AIMS:The purpose of this study was to compare technical and clinical outcomes in patients undergoing duodenal or colonic SEMS ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1932-3
更新日期：2012-03-01 00:00:00
abstract：:The motor function of the gallbladder after partial distal gastrectomy for gastric carcinoma (Billroth-I reconstruction) and its relationship to the motor function of the stomach was investigated using a double-isotope method. In this method, [99mTc]N-54-pyridoxyl-5-methyltryptophan ([99mTc]PMT) was utilized as a trac...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02064968
更新日期：1995-04-01 00:00:00
abstract：:This study determined how the luminal surface hydrophobicity and transmucosal potential difference (PD) of canine gastric mucosa changed during the recovery period after the tissue was challenged with acidified aspirin. Luminal aspirin reduced both the contact angle and PD of mucosae incubated in Ussing chambers. Afte...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02065551
更新日期：1995-06-01 00:00:00
abstract：:Patients with symptomatic cholelithiasis who represent higher than normal surgical risks may be the most suitable candidates for medical dissolution of gallstones. Chenodeoxycholic acid was given to 97 patients in a dosage of 15 mg/kg of body weight per day for a period of two years. Complete gallstone dissolution occ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/BF01308157
更新日期：1983-06-01 00:00:00
abstract：BACKGROUND:The endoscopic detection of esophageal cancer is suboptimal in both patients referred with dyspeptic symptoms and those enrolled in Barrett's surveillance programs. MCM5 expression in cells collected from gastric fluid may be correlated with the presence of dysplasia or adenocarcinoma. Analysis of this bioma...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05607-5
更新日期：2019-10-01 00:00:00
abstract：:The value of a "bread-barium" swallow for diagnosis of disordered esophageal motility was examined in 53 patients, 20 of whom complained of dysphagia, 20 retrosternal chest pain, and 13 heartburn; a further 19 subjects served as controls. Esophageal manometry in the patients with dysphagia and chest pain revealed majo...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01295808
更新日期：1983-12-01 00:00:00
