Neutrophil infiltration of the colon is independent of the FPR1 yet FPR1 deficient mice show differential susceptibilities to acute versus chronic induced colitis.

abstract：:Lichen planus is a common mucocutaneus disorder that rarely involves the esophagus. We report two challenging cases presenting with recurrent dysphagia originally suspected due to gastroesophageal reflux. Subsequent evaluation revealed peculiar endoscopic findings of desquamative esophagitis leading to the diagnosis o...

journal_title：Digestive diseases and sciences

authors： Ukleja A,DeVault KR,Stark ME,Achem SR

更新日期：2001-10-01 00:00:00

abstract：:Bile acids, such as deoxycholic acid (DC), are known to mediate some of their actions by differentially activating various protein kinase C (PKC) isoforms. This study confirms that DC induces apoptosis in gastric epithelial cells through PARP and caspase cascade activation, and examined the role of PKC in DC-induced a...

journal_title：Digestive diseases and sciences

authors： Redlak MJ,Power JJ,Miller TA

更新日期：2006-05-01 00:00:00

abstract：:Gastroesophageal reflux and clearance of the refluxed material can be measured by plotting a time-activity curve from an esophageal area of interest after 1 mCi of 99mTc sulfur colloid is placed in the stomach. Control subjects do not have peaks exceeding a value twice that of the baseline count levels. Reflux patient...

journal_title：Digestive diseases and sciences

authors： Velasco N,Pope CE 2nd,Gannan RM,Roberts P,Hill LD

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Obesity and metabolic syndrome are risk factors for colorectal neoplasia (CRN). However, the association between metabolically healthy obese (MHO) or metabolically unhealthy non-obese (MUNO) status and the risk of CRN remains unclear. AIMS:We aimed to elucidate the association between MHO or MUNO status and...

journal_title：Digestive diseases and sciences

authors： Kim NH,Jung YS,Park JH,Park DI,Sohn CI

更新日期：2018-11-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection is a major etiology of chronic liver disease worldwide. In the past decade, nonalcoholic fatty liver disease (NAFLD) has emerged as a common liver disorder in general population. Accordingly, the patient number of chronic hepatitis B (CHB) concomitant with NAFLD grows rapidly. The pre...

journal_title：Digestive diseases and sciences

authors： Lin CW,Huang XL,Liu HL,Wang Y

更新日期：2015-12-01 00:00:00

abstract：:The perception that chronic hepatitis C is an asymptomatic disease contrasts with many studies that show a strong association between chronic hepatitis C, hepatocellular cancer, and fatal liver disease. In order to resolve these issues, it is logical to directly evaluate the quality of life in patients with chronic he...

journal_title：Digestive diseases and sciences

authors： Carithers RL Jr,Sugano D,Bayliss M

更新日期：1996-12-01 00:00:00

abstract：:The effect of dopamine on human gastric and small intestinal interdigestive motility was investigated in 12 subjects. Intestinal motility was recorded by means of a four-lumen polyvinyl probe with four open tips located 15 cm apart, continuously perfused with distilled water. In each subject during the same study, aft...

journal_title：Digestive diseases and sciences

authors： Marzio L,Neri M,Di Giammarco AM,Cuccurullo F,Lanfranchi GA

更新日期：1986-04-01 00:00:00

abstract：:Growing evidence suggests that complex gene and environment interactions underlie a number of diseases including chronic inflammatory diseases of the digestive system. The rapid advances in information and technology provide opportunities to discover the risks or etiology for a variety of disorders within individual p...

journal_title：Digestive diseases and sciences

authors： Whitcomb DC,Aoun E,Vodovotz Y,Clermont G,Barmada MM

更新日期：2005-12-01 00:00:00

abstract：:Diamine oxidase (DAO) is an enzyme whose low plasma values are enhanced by an intravenous injection of heparin, which releases the enzyme from the enterocytes of the villous tips. In 20 normal controls and 15 untreated subjects affected with an overt malabsorption syndrome and subtotal atrophy shown by Crosby jejunal ...

journal_title：Digestive diseases and sciences

authors： D'Agostino L,Ciacci C,Daniele B,Barone MV,Sollazzo R,Mazzacca G

更新日期：1987-03-01 00:00:00

abstract：:The pathophysiology of constipation after rectopexy remains unclear: acquired anorectal dysfunction or preoperative colonic state are, by turns, the supposed culprit. The aim of this prospective study was to characterize the colorectal motility abnormalities encountered after such a surgical procedure. Twelve patients...

journal_title：Digestive diseases and sciences

authors： Siproudhis L,Ropert A,Gosselin A,Bretagne JF,Heresbach D,Raoul JL,Gosselin M

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

journal_title：Digestive diseases and sciences

authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

更新日期：2008-08-01 00:00:00

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The relationship of gastric cancer to the presence of interleukin-8 (IL-8) 251 T/A has been reported with conflicting results. AIM:To further explore the association of IL-8 251 allele polymorphism with gastric cancer susceptibility. METHODS:We performed an extensive search of relevant studies and carried ...

journal_title：Digestive diseases and sciences

authors： Wang J,Pan HF,Hu YT,Zhu Y,He Q

更新日期：2010-07-01 00:00:00

abstract：:In previous open studies, misoprostol and metronidazole reduced nonsteroidal anti-inflammatory drug-induced intestinal permeability changes and inflammation respectively. We assessed the effects of indomethacin treatment (50 mg three times a day) for one week with either coadministered metronidazole (400 mg twice a da...

journal_title：Digestive diseases and sciences

authors： Davies GR,Wilkie ME,Rampton DS

更新日期：1993-03-01 00:00:00

abstract：:Twenty-four patients with chronic active HCV infection, nonresponders to a previous treatment cycle with recombinant interferon-alpha (r-IFNA), underwent retreatment with leukocyte (LE-) IFN-alpha. This was administered at the dose of 3 MU three times a week, for either six months (group A) or 12 months (group B). All...

journal_title：Digestive diseases and sciences

authors： Scotto G,Grimaldi M

更新日期：1998-10-01 00:00:00

abstract：AIM:Renal toxicity of adefovir disoproxil (ADV) and tenofovir disoproxil fumarate (TDF) is a significant concern in chronic hepatitis B (CHB) patients. Early observational clinical data suggested that telbivudine (LdT) might have renoprotective effects. METHODS:In this prospective study, consecutive CHB patients on co...

journal_title：Digestive diseases and sciences

authors： Mak LY,Liu SH,Yap DY,Seto WK,Wong DK,Fung J,Chan TM,Lai CL,Yuen MF

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Assessment and quantification of actual liver function is crucial in patients with chronic liver disease to monitor disease progression and predict individual prognosis. Mathematical models, such as model for end-stage liver disease, are used for risk stratification of patients with chronic liver disease but...

journal_title：Digestive diseases and sciences

authors： Malinowski M,Jara M,Lüttgert K,Orr J,Lock JF,Schott E,Stockmann M

更新日期：2014-12-01 00:00:00

abstract：:Impaired gallbladder emptying is one of the various factors suggested to be involved in the pathogenesis of gallstones. The present study was undertaken to determine whether gallbladder emptying, endogenous cholecystokinin (CCK) secretion, or their interrelation is altered in patients with gallstones. After intraduode...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Driessen WM,Geuskens LM,Lamers CB

更新日期：1989-03-01 00:00:00

abstract：AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...

journal_title：Digestive diseases and sciences

authors： Bafford AC,Latushko A,Hansraj N,Jambaulikar G,Ghazi LJ

更新日期：2017-08-01 00:00:00

abstract：:We have studied pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells. Monolayers were formed after approximately 48 hr. Pepsinogen synthesis was studied by adding 14C-labeled amino acids to the culture medium. Basal secretion of de novo synthesized pepsinogen after 4 hr was 4 ...

journal_title：Digestive diseases and sciences

authors： Defize J,Hunt RH

更新日期：1988-12-01 00:00:00

abstract：:Animal studies have shown that calcium blocking drugs decrease lower esophageal sphincter pressure and inhibit peristaltic amplitude and duration. In a single-dose acute study, we compared the effects of a new oral calcium blocker, diltiazem (90, 120, 150 mg) with placebo in five volunteers and 10 patients with chest ...

journal_title：Digestive diseases and sciences

authors： Richter JE,Spurling TJ,Cordova CM,Castell DO

更新日期：1984-07-01 00:00:00

abstract：:Current research in gene delivery to the liver is focused on the intravenous, intraarterial, intraportal, or intratumoral route. Another possible route for gene delivery is via the common bile duct through endoscopic retrograde cholangiopancreatography (ERCP). Whether bile and pancreatic juice have any effect on gene ...

journal_title：Digestive diseases and sciences

authors： Xie X,Forsmark CE,Lau JY

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:This study aimed to objectively investigate whether the addition of polydextrose to sterilized probiotic containing Lactobacillus helveticus will confer benefits to constipation-predominant irritable bowel syndrome patients. METHODS:A total of 163 patients were randomized into two groups: Group A to consume...

journal_title：Digestive diseases and sciences

authors： Bahrudin MF,Abdul Rani R,Tamil AM,Mokhtar NM,Raja Ali RA

更新日期：2020-02-01 00:00:00

abstract：:Autoregulation of blood flow in the denervated, autoperfused dog stomach was studied before and during local intraarterial infusion of histamine. Histamine caused an increase in gastric blood flow and oxygen uptake. The increased oxygen uptake was due entirely to an increased blood flow, ie, oxygen extraction was not ...

journal_title：Digestive diseases and sciences

authors： Perry MA,Murphree D,Granger DN

更新日期：1982-08-01 00:00:00

abstract：:Chronic dyspepsia is common in children. However, the association of individual predominant symptoms with gastric emptying and their impact on nutritional status are poorly defined. We therefore studied 31 children (mean age 11 years, 14 boys) with chronic dyspepsia and classified their predominant symptoms (PS) by th...

journal_title：Digestive diseases and sciences

authors： Papadopoulou A,Vazeou A,Siafakas C,Papadimitriou A,Bartsocas C

更新日期：2002-01-01 00:00:00

abstract：:Effects of selective beta-adrenoceptor agonists on rectosigmoid motility during prolonged rectal distension were studied in 12 healthy volunteers in a double-blind, randomized fashion. Continuous distension was performed with a balloon in the proximal part of the rectum. Pressure was recorded by this balloon and by a ...

journal_title：Digestive diseases and sciences

authors： Lyrenäs E,Abrahamsson H,Dotevall G

更新日期：1985-06-01 00:00:00

abstract：:To evaluate the influence of chronic alcoholism on clinical features of chronic pancreatitis in Japan, pain evolution, pancreatic insufficiency, and long-term prognosis were studied by comparing chronic alcoholic pancreatitis (N = 88) with idiopathic pancreatitis (N = 67). The 155 patients with known course of the dis...

journal_title：Digestive diseases and sciences

authors： Hayakawa T,Kondo T,Shibata T,Sugimoto Y,Kitagawa M

更新日期：1989-01-01 00:00:00

abstract：:This study was designed to evaluate the role of 111In-labeled leukocyte imaging and fecal excretion in the assessment of inflammatory bowel disease. We compared these tests to various indices of disease activity in Crohn's disease, to Truelove's grading in ulcerative colitis, and to endoscopy, x-ray, and pathology in ...

journal_title：Digestive diseases and sciences

authors： Leddin DJ,Paterson WG,DaCosta LR,Dinda PK,Depew WT,Markotich J,McKaigney JP,Groll A,Beck IT

更新日期：1987-04-01 00:00:00

abstract：:A randomized controlled clinical study was conducted to determine (a) whether basic aluminum sucrose sulfate (sucralfate) is effective in preventing or reducing gastric ulcer recurrence, and (b) the clinical parameters contributing to ulcer recurrence after endoscopically proved healing has been effected. A total of 1...

journal_title：Digestive diseases and sciences

authors： Miyake T,Ariyoshi J,Suzaki T,Oishi M,Sakai M,Ueda S

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND AIM:The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect on their regeneration. In this study, we examined whether the pre-activate...

journal_title：Digestive diseases and sciences

authors： Arioka Y,Ito H,Ando T,Ogiso H,Hirata A,Hara A,Seishima M

更新日期：2015-06-01 00:00:00