Abstract:
:Cyclic vomiting syndrome is a disorder characterized by recurrent episodes of nausea and vomiting with complete resolution of symptoms between attacks. Nitric oxide plays a critical role in regulating several components of gastrointestinal mucosal defense and injury. Interleukin-6 has a wide variety of actions in the gastrointestinal apparatus. The purpose of this study was to evaluate the synthesis and release of nitric oxide and interleukin-6 by the esophageal and gastric mucosa in 10 children with cyclic vomiting syndrome, during symptom-free periods, and in 10 controls. The nitric oxide and interleukin-6 release by esophageal mucosa cells obtained from cyclic vomiting patients was quite similar to that in controls, but the release of nitric oxide from gastric mucosa cells of patients was significantly higher than that of controls. Conversely, no interleukin-6 was detectable in gastric mucosa cell supernatants in any of the patients. Further studies are needed to evaluate the relationship between factors triggering cyclic vomiting syndrome and the release of nitric oxide and interleukin-6 by gastric mucosa.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Zicari A,Corrado G,Pacchiarotti C,Lucarelli S,Frediani T,Cavaliere M,Porcelli M,Cardi Edoi
10.1023/a:1010712703685subject
Has Abstractpub_date
2001-04-01 00:00:00pages
831-5issue
4eissn
0163-2116issn
1573-2568journal_volume
46pub_type
杂志文章abstract:BACKGROUND:Little is known on practice patterns of endoscopists for the management of Barrett's esophagus (BE) over the last decade. AIMS:Our aim was to assess practice patterns of endoscopists for the diagnosis, surveillance and treatment of BE. METHODS:All members of the Italian Society of Digestive Endoscopy (SIED...
journal_title:Digestive diseases and sciences
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更新日期:2020-09-28 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Digestive diseases and sciences
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更新日期:1992-03-01 00:00:00
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journal_title:Digestive diseases and sciences
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更新日期:1994-07-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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更新日期:1984-05-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1023/a:1018868126743
更新日期:1998-06-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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更新日期:1982-08-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308313
更新日期:1980-02-01 00:00:00
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doi:10.1007/s10620-012-2399-6
更新日期:2013-03-01 00:00:00
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更新日期:1996-07-01 00:00:00
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更新日期:2019-05-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01537413
更新日期:1990-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01338533
更新日期:1980-11-01 00:00:00