Enhanced expression of transforming growth factor (TGF) -alpha precursor and TGF-beta1 during Paneth cell regeneration.

abstract：:The effects of cisapride on upper gut motility were studied in seven healthy volunteers by means of a novel intraluminal electromyographic technique in a placebo-controlled study. In the interdigestive state, cisapride (10 mg intravenous bolus injection) markedly increased the number of spike bursts. The most obvious ...

journal_title：Digestive diseases and sciences

authors： Coremans G,Janssens J,Vantrappen G,Chaussade S,Ceccatelli P

更新日期：1988-12-01 00:00:00

abstract：:Impaired gallbladder emptying is one of the various factors suggested to be involved in the pathogenesis of gallstones. The present study was undertaken to determine whether gallbladder emptying, endogenous cholecystokinin (CCK) secretion, or their interrelation is altered in patients with gallstones. After intraduode...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Driessen WM,Geuskens LM,Lamers CB

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:Pancreas divisum (PD) as a cause of pancreatitis has been debated. In this study, we report the association of multiple gene polymorphisms on the risk of RAP in the presence of PD. DESIGN:We enrolled 687 individuals (167 IRAP, 276 ICP, and 244 unrelated healthy controls) from May 2015 to September 2016. Pat...

journal_title：Digestive diseases and sciences

authors： Talukdar R,Aslam M,Reddy DN,Nabi Z,Shava U,Ravikanth VV,Avanthi S,Govardhan B

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:We hypothesized that the severity of dextran sodium sulfate (DSS)-induced colitis could differ between DSS preparations of the same molecular weight, and that this difference may be affected by the sulfur content. To test this, we used three DSS preparations of similar molecular weights but with different su...

journal_title：Digestive diseases and sciences

authors： Bamba S,Andoh A,Ban H,Imaeda H,Aomatsu T,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Araki Y,Fujiyama Y

更新日期：2012-02-01 00:00:00

abstract：:Endoscopic papillary balloon dilatation (EPBD) has been recently used in conjunction with endoscopic sphincterotomy (EST) for the removal of common bile duct (CBD) stones. The present study was aimed at assessing the safety and outcome of sequential EPBD following EST for CBD stones. A total of 74 patients (43 females...

journal_title：Digestive diseases and sciences

authors： Kochhar R,Dutta U,Shukla R,Nagi B,Singh K,Wig JD

更新日期：2009-07-01 00:00:00

abstract：:The effect of ursodeoxycholic acid (UDCA) on bile lipid composition and bile acid kinetics was evaluated in seven cholesterol gallstone patients following one month of UDCA administration (12 mg/kg/day). UDCA administration induces a significant reduction in the cholesterol saturation index (SI). After UDCA treatment,...

journal_title：Digestive diseases and sciences

authors： Roda E,Roda A,Sama C,Festi D,Mazzella G,Aldini R,Barbara L

更新日期：1979-02-01 00:00:00

abstract：:The aim of the present study was to investigate the antioxidative effects of water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), on ischemia-reperfusion (I/R) -induced gastric mucosal injury in rats. Gastric ischemia was induced by applying a small clamp to the c...

journal_title：Digestive diseases and sciences

authors： Ichikawa H,Yoshida N,Takano H,Ishikawa T,Handa O,Takagi T,Naito Y,Murase H,Yoshikawa T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Lysyl oxidase (LOX) is frequently overexpressed in a variety of malignancies and involved in tumor invasion and metastasis. Furthermore, it has been shown that LOX is closely related to vascular endothelial growth factor (VEGF). AIMS:In this study, we aimed to investigate the exact role of LOX and the corre...

journal_title：Digestive diseases and sciences

authors： Zhu J,Huang S,Wu G,Huang C,Li X,Chen Z,Zhao L,Zhao Y

更新日期：2015-10-01 00:00:00

abstract：:MR enteroclysis is becoming a very important imaging modality in the workup and follow-up of small bowel diseases. The technique has many advantages, including the absence of ionizing radiation, ability to control luminal distension, superior tissue characterization, multiplanar capabilities, and mural and extramural ...

journal_title：Digestive diseases and sciences

authors： Wiarda BM,Kuipers EJ,Houdijk LP,Tuynman HA

更新日期：2005-06-01 00:00:00

abstract：:Magnifying videoendoscopic observation of a minute lesion with a single IIIL type cryptal orifice was reported. This minute lesion was a single-gland adenoma accompanied histopathologically by a bud of adenomatous gland and was located in the upper part of the mucosa. This finding regarding a pit pattern should make p...

journal_title：Digestive diseases and sciences

authors： Tamura S,Nakajo K,Kitamura M,Kamiji I,Onishi S

更新日期：2002-10-01 00:00:00

abstract：:We prospectively assessed the relationship between nodular gastritis and Helicobacter pylori infection. Of 1409 adults who underwent endoscopy for persistent dyspepsia between June 2004 and August 2005, 41 (2.9%) patients were diagnosed with nodular gastritis (11 [27%] men and 30 [73%] women). The mean age was 45.9 ye...

journal_title：Digestive diseases and sciences

authors： Chen MJ,Wang TE,Chang WH,Liao TC,Lin CC,Shih SC

更新日期：2007-10-01 00:00:00

abstract：:Three cases of gastritis glandularis et cystica profunda are presented, two associated with severe chronic gastritis and the other with invasive gastric carcinoma and chronic gastritis. This poorly known entity consists of benign downgrowths of deep gastric glands through the muscularis mucosae into the submucosa. The...

journal_title：Digestive diseases and sciences

authors： Honoré LH,Lewis AS,O'Hara KE

更新日期：1979-01-01 00:00:00

abstract：:This study investigated the effects of portal hypertension on gastric motor and secretory functions and the role of endothelin in rats. Control; sham-operated; endothelin-A receptor blocker, BQ 485 (1 microgram/kg)-treated; portal hypertensive; and portal hypertension +, endothelin-A receptor blocker-treated rats were...

journal_title：Digestive diseases and sciences

authors： Günal O,Yeğen C,Aktan AO,Yalin R,Yeğen BC

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Human hepatocellular carcinoma (HCC) is one of the most common fatal cancers and an important health problem worldwide, but its mechanism is still unclear. Microtubule (MT) kinesin motor proteins orchestrate a variety of cellular processes (e.g. mitosis, motility and organelle transportation) and have been i...

journal_title：Digestive diseases and sciences

authors： Huang X,Liu F,Zhu C,Cai J,Wang H,Wang X,He S,Liu C,Yao L,Ding Z,Zhang Y,Zhang T

更新日期：2014-04-01 00:00:00

abstract：:We report a case of dissecting aneurysm of the celiac axis and hepatic artery resulting in obstructive jaundice. The aneurysm was demonstrated both by ultrasound and by angiography, but the associated aortic dissection was apparent only on CT scan. The patient was treated with percutaneous transhepatic biliary drainag...

journal_title：Digestive diseases and sciences

authors： Bret PM,Partensky C,Bretagnolle M,Paliard P,Burke M

更新日期：1987-12-01 00:00:00

abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...

journal_title：Digestive diseases and sciences

authors： Heresbach D,Bretagne JF,Raoul JL,Moisan A,Siproudhis L,Devillers A,Gosselin M

更新日期：1993-09-01 00:00:00

abstract：:We report the findings in two sisters with active cirrhosis and an anti-liver-kidney microsomal antibody (anti-LKM) of the autoimmune type. This unusual disease is characterized by the presence of high levels of antibodies that react with the smooth and rough endoplasmic reticulum of the liver and other tissues. Our p...

journal_title：Digestive diseases and sciences

authors： Buffet C,Homberg JC,Pelletier G,Turner K,Etienne JP

更新日期：1986-11-01 00:00:00

abstract：:The role of mucosal T-cell activation in HIV-associated enteropathy is uncertain. Twenty Zambian patients with AIDS and chronic diarrhea were studied, as were nine controls. Distal duodenal biopsies were taken at endoscopy. Morphometric analysis and dual color immunofluorescence staining were performed. Villous height...

journal_title：Digestive diseases and sciences

authors： Veitch AM,Kelly P,Zulu I,MacDonald TT,Farthing MJ

更新日期：2001-05-01 00:00:00

abstract：:Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...

journal_title：Digestive diseases and sciences

authors： Guo JP,Maurer AH,Fisher RS,Parkman HP

更新日期：2001-01-01 00:00:00

abstract：:The frequent association of stromal tumors with neurofobromatosis raises high suspicion of a possible correlation between the two entities. The aim of this study was to analyze clinicopathologic features of patients with concomitant neurofibromatosis and gastrointestinal stromal tumors and to discuss the molecular bas...

journal_title：Digestive diseases and sciences

authors： Cheng SP,Huang MJ,Yang TL,Tzen CY,Liu CL,Liu TP,Hsiao SC

更新日期：2004-08-01 00:00:00

abstract：:Opioids, both endogenous and exogenous, have been shown to exert a modulating influence on many gastrointestinal functions. Animal studies suggest an inhibitory role for opioids in the control of pancreatic secretion, which may be exerted through their inhibitory effect on acetylcholine release from intramural neurons...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Saad C,Valenzuela JE

更新日期：1988-05-01 00:00:00

abstract：:The purpose of this study was to examine the effect of perfusion of the colon with a fatty acid (oleic acid) on peptone-stimulated gastric acid secretion and release of gastrin in conscious dogs. Gastric acid secretion was monitored by continuous intragastric titration. Perfusion of the colon with sodium oleate (24 mm...

journal_title：Digestive diseases and sciences

authors： Hashimoto T,Lluis F,Gomez G,Hill FL,Greeley GH Jr,Thompson JC

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Bowel-cleansing studies are frequently underpowered, poorly designed, and with subjective assessments. Consensus on tolerability of the bowel-cleansing agents is thus lacking. This study developed and validated a bowel-preparation tolerability questionnaire and used it to assess the tolerabili...

journal_title：Digestive diseases and sciences

authors： Lawrance IC,Willert RP,Murray K

更新日期：2013-04-01 00:00:00

abstract：:Many physiological factors can alter gastric emptying, and the role of gastric emptying in functional dyspepsia is controversial. The aim of this study was to assess the effects of different factors (age, sex, the degree of dyspeptic and irritable bowel symptoms, lactase deficiency, smoking habits, the use of antiinfl...

journal_title：Digestive diseases and sciences

authors： Koskenpato J,Kairemo K,Korppi-Tommola T,Färkkilä M

更新日期：1998-06-01 00:00:00

abstract：:Alterations in smooth muscle responsiveness and neural pathways in adjacent tissue may occur after local myenteric denervation. The in vitro contractile responses of both longitudinal and circular muscle to the mixed muscarinic and nicotinic cholinergic agonist carbachol were determined 15, 30, and 45 days after local...

journal_title：Digestive diseases and sciences

authors： Herman JR,Bass P

更新日期：1990-09-01 00:00:00

abstract：:Cytomegalovirus (CMV) inclusions were found at colonic perforation sites in three patients with clinical settings suggesting a compromised immunologic status. This could be interpreted as: (1) CMV was an etiologic agent in these perforations; or (2) CMV was an opportunistic superinfection in areas of preexisting infla...

journal_title：Digestive diseases and sciences

authors： Goodman ZD,Boitnott JK,Yardley JH

更新日期：1979-05-01 00:00:00

abstract：:Twelve patients with recurrent polyserositis (RP, familial Mediterranean fever) on colchicine prophylaxis (1.0-2.0 mg daily) for three years or more were evaluated for the presence of gastrointestinal effects possibly attributable to the drug. Two patients had bulky stools, two others had transient diarrhea, and one h...

journal_title：Digestive diseases and sciences

authors： Ehrenfeld M,Levy M,Sharon P,Rachmilewitz D,Eliakim M

更新日期：1982-08-01 00:00:00

abstract：:Lafutidine, a histamine H2-receptor antagonist, exhibits gastric mucosal protective action mediated by capsaicin-sensitive afferent neurons, in addition to a potent antisecretory effect. In this study we examined the effect of lafutidine on dextran sulfate Na (DSS)-induced ulcerative colitis in rats, in relation to ca...

journal_title：Digestive diseases and sciences

authors： Okayama M,Tsubouchi R,Kato S,Takeuchi K

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:In liver cirrhosis, intestinal mucus barrier is rarely studied. AIMS:This study aimed to investigate whether mucus barrier in ileum is altered in cirrhotic rats and its underlying mechanisms. METHODS:Thioacetamide was injected to induce liver cirrhosis in rats. Serum from portal vein blood, and ileum and l...

journal_title：Digestive diseases and sciences

authors： Zhang L,Tai Y,Tang S,Zhao C,Tong H,Gao J,Tang C

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00