Altered carbachol-induced contractile responses of rat jejunal smooth muscle following local myenteric plexus ablation.

abstract：:The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

journal_title：Digestive diseases and sciences

authors： Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

更新日期：1998-11-01 00:00:00

abstract：:Pharmacological agents that might influence the poststimulus rebound contractile response (PSRR) through an action on the intrinsic inhibitory innervation of the circular muscle coat were studied in the large intestine of the piebald mouse model for Hirschsprung's disease. Tetrodotoxin (0.3-3 microM) suppressed, in a ...

journal_title：Digestive diseases and sciences

authors： Wood JD,Brann LR

更新日期：1986-07-01 00:00:00

abstract：:Gallbladder contractility has been studied in 21 obese patients (greater than 130% ideal weight) and 30 nonobese subjects before and at regular intervals after the administration of a regular solid-liquid meal, and after a low-calorie, low-fat meal used conventionally for weight-loss purposes (Modifast). Gallbladder v...

journal_title：Digestive diseases and sciences

authors： Marzio L,Capone F,Neri M,Mezzetti A,De Angelis C,Cuccurullo F

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Gut dysmotility is closely associated with proinflammatory cytokines both in irritable bowel syndrome and inflammatory bowel disease. There is a dose-response relationship between depression and these inflammatory cytokines. AIMS:In the present study, we aimed to investigate the effect of Interleukin-6 (IL-...

journal_title：Digestive diseases and sciences

authors： Zhang L,Hu L,Chen M,Yu B

更新日期：2013-08-01 00:00:00

abstract：BACKGROUNDS AND AIMS:We studied the intestinotrophic hormone glucagon-like peptide-2 (GLP-2) as a possible therapy for non-steroidal anti-inflammatory drug (NSAID)-induced intestinal ulcers. Luminal nutrients release endogenous GLP-2 from enteroendocrine L cells. Since GLP-2 is degraded by dipeptidyl peptidase IV (DPPI...

journal_title：Digestive diseases and sciences

authors： Inoue T,Higashiyama M,Kaji I,Rudenkyy S,Higuchi K,Guth PH,Engel E,Kaunitz JD,Akiba Y

更新日期：2014-06-01 00:00:00

abstract：:We present the case of a 60-year-old male patient, who had several episodes of melena during the last years. One month ago he had a new episode of digestive bleeding, and an endoscopic study was performed that showed at 35 cm from the dental arcade a polypoid, pedunculated lesion, with a diameter of 5 cm and a submuco...

journal_title：Digestive diseases and sciences

authors： Bosch O,González Campos C,Jurado A,Guijo I,Miro C,Renedo G,Porres JC

更新日期：1994-12-01 00:00:00

abstract：:We report four patients with pneumothorax as a complication of ERCP with sphincterotomy. With conservative treatment all patients recovered. Previously, 16 comparable cases have been reported in the literature. The main risk factor for this rare complication seems (pre-cut) sphincterotomy. Pneumothorax is usually righ...

journal_title：Digestive diseases and sciences

authors： Schepers NJ,van Buuren HR

更新日期：2012-08-01 00:00:00

abstract：:The authors have developed a primate model for evaluating cytoprotection against alcohol-induced injury in gastric mucosa pretreated with antiulcer agents. In the present study, groups of squirrel monkeys received either a single oral dose of misoprostol (500 or 200 micrograms/kg), cimetidine (3 or 6 mg/kg), placebo, ...

journal_title：Digestive diseases and sciences

authors： Liss RH,Letourneau RJ,Schepis JP

更新日期：1986-02-01 00:00:00

abstract：AIM:To evaluate the use of health care resources and the associated costs of complex perianal Crohn's disease (CD) from the National Health System perspective. METHODS:We conducted a multicenter, retrospective, observational study in which gastroenterologists from 11 hospitals in the Community of Madrid took part. Dat...

journal_title：Digestive diseases and sciences

authors： Chaparro M,Zanotti C,Burgueño P,Vera I,Bermejo F,Marín-Jiménez I,Yela C,López P,Martín MD,Taxonera C,Botella B,Pajares R,Ponferrada A,Calvo M,Algaba A,Pérez L,Casis B,Maté J,Orofino J,Lara N,García-Losa M,Badia

更新日期：2013-12-01 00:00:00

abstract：:In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...

journal_title：Digestive diseases and sciences

authors： Phillips WT,Schwartz JG,McMahan CA

更新日期：1993-01-01 00:00:00

abstract：:The headword "overlap syndromes" of liver diseases includes the coexistence of autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis. These syndromes often represent a diagnostic and therapeutic challenge for hepatologists; it remains unclear whether these overlap syndromes form distinct ...

journal_title：Digestive diseases and sciences

authors： Durazzo M,Premoli A,Paschetta E,Belci P,Spandre M,Bo S

更新日期：2013-02-01 00:00:00

abstract：:Viral dynamic studies in chronic hepatitis C virus (HCV) infection indicate a significantly shortened survival of virus-infected cells. Since at the steady state of chronic viral infection, the rate of infected cell elimination equals new cell regeneration, this would imply a high rate of hepatocyte turnover in chroni...

journal_title：Digestive diseases and sciences

authors： Lake-Bakaar G,Mazzoccoli V,Ruffini L

更新日期：2002-07-01 00:00:00

abstract：:Gastritis, an inflammatory state in gastric mucosa, can be induced experimentally in various ways. The present study considered the iodoacetamide model (Iodo). Omega-3 fatty acids (fish oil), black seed oil, and curcuminoids (natural products) in addition to omeprazole (synthetic proton-pump inhibitor) were tested. Su...

journal_title：Digestive diseases and sciences

authors： Elseweidy MM,Younis NN,Amin RS,Abdallah FR,Fathy AM,Yousif ZA

更新日期：2008-07-01 00:00:00

abstract：:Because of marked improvement in diagnosis and management, cystic fibrosis is now more frequently noted in young adults, many of whom have only mild clinical forms. Pancreatitis is a known complication of cystic fibrosis and may occur at any time in the course of the disease; in rare instances, pancreatitis is the fir...

journal_title：Digestive diseases and sciences

authors： Masaryk TJ,Achkar E

更新日期：1983-10-01 00:00:00

abstract：:Isolated case reports in which symptomatic hearing loss develops suddenly during the course of inflammatory bowel disease (IBD) have been reported, but the presence of subclinical sensorineural hearing loss (SNHL) associated with IBD has been investigated in only two preliminary studies. In order to research this furt...

journal_title：Digestive diseases and sciences

authors： Akbayir N,Caliş AB,Alkim C,Sökmen HM,Erdem L,Ozbal A,Bölükbaş F,Akbayir N

更新日期：2005-10-01 00:00:00

abstract：:MR enteroclysis is becoming a very important imaging modality in the workup and follow-up of small bowel diseases. The technique has many advantages, including the absence of ionizing radiation, ability to control luminal distension, superior tissue characterization, multiplanar capabilities, and mural and extramural ...

journal_title：Digestive diseases and sciences

authors： Wiarda BM,Kuipers EJ,Houdijk LP,Tuynman HA

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Safety-net hospitals are enriched in ethnic minorities and provide opportunities for high-impact hepatitis B virus (HBV) screening. AIM:We aim to evaluate the impact of a pilot program integrating HBV screening into outpatient endoscopy among urban safety-net populations. METHODS:From July 2015 to May 2017...

journal_title：Digestive diseases and sciences

authors： Campbell B,Lopez A,Liu B,Bhuket T,Wong RJ

更新日期：2018-01-01 00:00:00

abstract：:For evaluation of the prognostic relevance of p53 expression in gastric cancer, the immunohistochemical tissue status of 133 primary gastric cancer patients was investigated for p53 expression and the association between p53 tissue status and clinicopathological parameters was analyzed. P53 immunoreactivity was detect...

journal_title：Digestive diseases and sciences

authors： Mönig SP,Eidt S,Zirbes TK,Stippel D,Baldus SE,Pichlmaier H

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Despite accumulating data on the pathogenesis of eosinophilic esophagitis, not much is known about risk factors for the development of the disease. The role of factors such as smoking, breastfeeding, early antibiotic exposure and other factors that have been associated with other allergic diseases has not be...

journal_title：Digestive diseases and sciences

authors： Slae M,Persad R,Leung AJ,Gabr R,Brocks D,Huynh HQ

更新日期：2015-11-01 00:00:00

abstract：:The specificity of polymerase chain reaction monoclonality in the diagnosis of gastric lymphoma was prospectively evaluated. Gastric mucosal tissue from normal gastric mucosa (N = 13), benign gastric ulcers (N = 3), chronic Helicobacter pylori gastritis (N = 3), gastric mucosa-associated lymphoid tissue (N = 16), and ...

journal_title：Digestive diseases and sciences

authors： Weston AP,Banerjee SK,Horvat RT,Cherian R,Campbell DR,Zoubine MN

更新日期：1998-02-01 00:00:00

abstract：:Many drugs have been used in the treatment of chronic hepatitis B, but with the exception of interferon, none have proved to be effective. Several studies have found that a sustained loss of viral replication occurs in approximately 40% of patients who started with a 16-week course of recombinant interferon alfa-2b gi...

journal_title：Digestive diseases and sciences

authors： Perrillo RP

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis is among the causes of refractory reflux disease. Biopsy of esophagus is the gold standard for diagnosis. In this study we determined the frequency of eosinophilic esophagitis (EE) in refractory reflux cases referred to Motility Department of Shahid Beheshti Research Center of Gastro...

journal_title：Digestive diseases and sciences

authors： Foroutan M,Norouzi A,Molaei M,Mirbagheri SA,Irvani S,Sadeghi A,Derakhshan F,Tavassoli S,Besharat S,Zali M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Primary liver cancer constitutes an increasingly malignancy in the Western world and one of the leading causes of cancer-related deaths worldwide. The purpose of this study was to evaluate and compare long-term outcomes after R0 resections in noncirrhotic livers for hepatocellular carcinoma (HCC) and intrahe...

journal_title：Digestive diseases and sciences

authors： Sotiropoulos GC,Bockhorn M,Sgourakis G,Brokalaki EI,Molmenti EP,Neuhäuser M,Radtke A,Wohlschlaeger J,Baba HA,Broelsch CE,Lang H

更新日期：2009-04-01 00:00:00

abstract：:An altered adaptive response of the pancreas and small intestine to nutritional stress has an adverse impact upon nutritional status in elderly humans or senescent rats. We evaluated the effects of a pancreatic extract nutritional supplement on intestinal mucosa adaptation in LPS-treated aged rats. Endotoxemic rats we...

journal_title：Digestive diseases and sciences

authors： Farges MC,Raul F,Cezard JP,Davot P,Meunier MT,Cynober L,Vasson MP

更新日期：1998-10-01 00:00:00

abstract：:The distribution of tissue kallikrein (TK) and its plasma inhibitor, kallistatin in plasma and intestinal tissue, was studied in patients with active ulcerative colitis (UC) and Crohn's disease (CD). TK was localized to goblet cells and kallistatin to epithelial cells of normal human intestine. Both proteins are visua...

journal_title：Digestive diseases and sciences

authors： Stadnicki A,Mazurek U,Gonciarz M,Plewka D,Nowaczyk G,Orchel J,Pastucha E,Plewka A,Wilczok T,Colman RW

更新日期：2003-03-01 00:00:00

abstract：UNLABELLED:Recent evidence suggests a role for gut bacteria and antibiotics in the pathophysiology and treatment of irritable bowel syndrome (IBS), respectively. While the benefits of the antibiotic rifaximin have demonstrated efficacy and durable improvement in symptoms over 3 months, the long-term need for retreatmen...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Morales W,Chua K,Barlow G,Weitsman S,Kim G,Amichai MM,Pokkunuri V,Rook E,Mathur R,Marsh Z

更新日期：2011-07-01 00:00:00

abstract：:Manometry is considered the gold standard for evaluating sphincter of Oddi dysfunction. It has recently been demonstrated that the ultrasound (US) secretin test proposed a few years ago as a noninvasive test for the study of sphincter of Oddi dysfunction yields a substantial percentage of pathological findings in pati...

journal_title：Digestive diseases and sciences

authors： Di Francesco V,Brunori MP,Rigo L,Toouli J,Angelini G,Frulloni L,Bovo P,Filippini M,Vaona B,Talamini G,Cavallini G

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SS) patients with severe esophageal affection have impaired peristalsis. However, motor function evaluated in vivo by manometry and fluoroscopy does not provide detailed information about the individual contraction cycles. AIMS:To apply, for the first time in gastrointestinal (GI) patien...

journal_title：Digestive diseases and sciences

authors： Gregersen H,Villadsen GE,Liao D

更新日期：2011-12-01 00:00:00

abstract：:The effect of smoking on interdigestive gastrointestinal motility is little studied but may play a role in gastrointestinal morbidity. We studied gastroduodenal motility in 10 volunteers (five smokers and five nonsmokers) using a water-perfused pressure catheter. A pH probe was placed in the duodenal bulb. Baseline mo...

journal_title：Digestive diseases and sciences

authors： McDonnell WM,Owyang C

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree of inflammation, while chemoprevention ...

journal_title：Digestive diseases and sciences

authors： Tang J,Sharif O,Pai C,Silverman AL

更新日期：2010-06-01 00:00:00