Metoclopramide inhibits development of esophageal varices in rat model.

abstract：:Leptin is a 16-kDa nonglycosylated protein primarily secreted from the adipocytes of white fat; minor levels of regulated leptin expression also occurs at other sites such as placenta, skeletal muscle, the stomach fundus, and culture-activated hepatic stellate cells (HSCs). Leptin is primarily involved in the regulati...

journal_title：Digestive diseases and sciences

authors： Bethanis SK,Theocharis SE

更新日期：2006-10-01 00:00:00

abstract：:Leptin is an adipocyte-derived hormone involved in the homeostasis of body composition. An imbalance in leptin regulation has been observed in patients with liver cirrhosis. We aimed to assess serum and ascitic leptin levels in a group of patients with decompensated liver cirrhosis and to evaluate the relationship of ...

journal_title：Digestive diseases and sciences

authors： Giannini E,Romagnoli P,Tenconi GL,Botta F,Malfatti F,Chiarbonello B,Mamone M,Barreca T,Testa R

更新日期：2004-02-01 00:00:00

abstract：:Twelve patients with recurrent polyserositis (RP, familial Mediterranean fever) on colchicine prophylaxis (1.0-2.0 mg daily) for three years or more were evaluated for the presence of gastrointestinal effects possibly attributable to the drug. Two patients had bulky stools, two others had transient diarrhea, and one h...

journal_title：Digestive diseases and sciences

authors： Ehrenfeld M,Levy M,Sharon P,Rachmilewitz D,Eliakim M

更新日期：1982-08-01 00:00:00

abstract：:Pancreatic function tests were performed in 11 adult cystic fibrosis (CF) patients with a fecal fat excretion of more than 10% during treatment with pancrease 2 capsules three times a day. These tests included urinary p-aminobenzoic acid (PABA) excretion, fasting serum trypsin and pancreatic polypeptide (PP), and gluc...

journal_title：Digestive diseases and sciences

authors： Heijerman HG,Lamers CB,Bakker W,Dijkman JH

更新日期：1993-01-01 00:00:00

abstract：AIM:To identify the clinical and biochemical predictors of histologic disease severity in patients with non-alcoholic steatohepatitis (NASH). METHOD:Clinical, anthropometric and biochemical data of 71 consecutive patients with a histological diagnosis of NASH were retrieved from the medical database. The histologic cr...

journal_title：Digestive diseases and sciences

authors： Singh DK,Sakhuja P,Malhotra V,Gondal R,Sarin SK

更新日期：2008-07-01 00:00:00

abstract：:Hyperglycemia slows gastric emptying and increases the intensity of perception of gastric distension during fasting and small intestinal nutrient stimulation. In order to examine the possibility that abnormalities of gastric electrical rhythm may be associated with the effects of hyperglycemia, the gastric electrical ...

journal_title：Digestive diseases and sciences

authors： Hebbard GS,Samson M,Andrews JM,Carman D,Tansell B,Sun WM,Dent J,Horowitz M

更新日期：1997-03-01 00:00:00

abstract：:Although various types of artificial liver support systems (ALSSs) including a hybrid type have been made, few are practical ALSSs for treatment of acute and/or chronic hepatic failure. Titanium oxide (TiO(2)), a stable material, dismantles various materials using a photocatalytic action under ultraviolet irradiation....

journal_title：Digestive diseases and sciences

authors： Shinohara H,Shimada M,Ikemoto T,Morine Y,Imura S,Fujii M,Imaizumi T,Murayama M,Aiba Y

更新日期：2007-09-01 00:00:00

abstract：:Interferon-alpha therapy for chronic hepatitis C in special patient populations raises a number of issues. Patients with hemophilia, kidney disease requiring hemodialysis, mixed cryoglobulinemia, HIV infection, and those receiving an allograft share some characteristics that complicate the treatment of hepatitis C vir...

journal_title：Digestive diseases and sciences

authors： Marcellin P,Boyer N,Behamou JP,Erlinger S

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in affluent countries. Recent studies have reported that circular RNAs (circRNAs) are important regulators of hepatic steatosis. However, the role and mechanism of circRNA in NAFLD are poorly understood. AIMS:This study is to ...

journal_title：Digestive diseases and sciences

authors： Li P,Shan K,Liu Y,Zhang Y,Xu L,Xu L

更新日期：2019-01-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：:Our objective was to determine whether there are dominating racial differences in patient preferences for surgery that may explain the disparities in proctocolectomy utilization between African Americans (AA) and whites. We used the time trade-off technique to measure health preferences for undergoing ileal pouch anal...

journal_title：Digestive diseases and sciences

authors： Nguyen GC,Tuskey A,Bayless TM,LaVeist TA,Brant SR

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Studies investigating the association between aspirin use and gastric cancer risk have reported conflicting results. The objective of this study was to quantitatively summarize the evidence for such a relationship. RESULTS:Two investigators independently searched the Medline, PubMed, Embase, and Academic Searc...

journal_title：Digestive diseases and sciences

authors： Yang P,Zhou Y,Chen B,Wan HW,Jia GQ,Bai HL,Wu XT

更新日期：2010-06-01 00:00:00

abstract：:Patients with Zollinger-Ellison syndrome whose gastric acid secretion or symptoms were not controlled by cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of cimetidine, used either alone or in combination with a long-acting anticholinergic agent,...

journal_title：Digestive diseases and sciences

authors： McCarthy DM,Hyman PE

更新日期：1982-04-01 00:00:00

abstract：:Macro-creatine-kinases are isoenzymes of creatinine-kinases (CK). They have been classified in two types: type 1 (CK bound to an immunoglobulin) and type 2 (an oligomeric mitochondrial CK). CK type 1 has been found in patients with ulcerative colitis (UC) but not in Crohn's disease (CD). However, there are no studies ...

journal_title：Digestive diseases and sciences

authors： Perez-Calle JL,Marin-Jimenez I,Lopez-Serrano P,Gisbert JP,Pena AS,Fernandez-Rodriguez C

更新日期：2008-02-01 00:00:00

abstract：:Clinical and experimental evidence indicates that estrogens are involved in the control of hepatocyte proliferation both in normal and in neoplastic conditions. Thirty-two cirrhotic patients with unresectable or otherwise untreatable hepatocellular carcinoma were allocated to receive either tamoxifen (30 mg/day) or no...

journal_title：Digestive diseases and sciences

authors： Farinati F,De Maria N,Fornasiero A,Salvagnini M,Fagiuoli S,Chiaramonte M,Naccarato R

更新日期：1992-05-01 00:00:00

abstract：:Isosmotic liquid peptone meals adjusted to pH 7, 3, and 1.5 were instilled on separate days into the stomachs of 8 duodenal ulcer patients and 7 healthy controls. Using a marker-dilution method, duodenal acid load (DAL) was measured as the amount of unbuffered hydrogen ions delivered to the duodenum per unit time. Gas...

journal_title：Digestive diseases and sciences

authors： Lam SK,Isenberg JI,Grossman MI,Lane WH,Hogan DL

更新日期：1982-07-01 00:00:00

abstract：:We report a case of dissecting aneurysm of the celiac axis and hepatic artery resulting in obstructive jaundice. The aneurysm was demonstrated both by ultrasound and by angiography, but the associated aortic dissection was apparent only on CT scan. The patient was treated with percutaneous transhepatic biliary drainag...

journal_title：Digestive diseases and sciences

authors： Bret PM,Partensky C,Bretagnolle M,Paliard P,Burke M

更新日期：1987-12-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a connective tissue disorder of unknown etiology characterized by fibrosis and vascular obliteration in the skin, gastrointestinal tract, lungs, and heart. Our aim was to investigate the autoantibody profile in patients with esophageal involvement of SSc and to describe the relationship bet...

journal_title：Digestive diseases and sciences

authors： Savas N,Dagli U,Ertugrul E,Kuran S,Sahin B

更新日期：2007-11-01 00:00:00

abstract：:The synthetic substrate cholyl-PABA, developed by conjugating cholic acid with paraaminobenzoic acid, is hydrolyzed by the bacterial enzyme cholyl hydrolase to release free PABA. This study aimed to evaluate whether quantitating urinary excretion of PABA after oral administration of cholyl-PABA can detect small intest...

journal_title：Digestive diseases and sciences

authors： Bardhan PK,Feger A,Kogon M,Muller J,Gillessen D,Beglinger C,Gyr N

更新日期：2000-03-01 00:00:00

abstract：:The secondary bile acid deoxycholic acid is believed to be a promoter of large bowel cancer, in part by inducing colonic epithelial proliferation. The effects of deoxycholic acid on [3H]thymidine incorporation by the human colon cancer cell line HT29 and two differentiated subclones were measured and compared. The sub...

journal_title：Digestive diseases and sciences

authors： Peiffer LP,Peters DJ,McGarrity TJ

更新日期：1997-11-01 00:00:00

abstract：:Nongranulomatous chronic idiopathic enterocolitis is characterized by sudden onset of severe watery diarrhea, malabsorption, exudative enteropathy, frequent appearance of shallow ulcerations, and variable degrees of villus atrophy. In the absence of infectious and pharmacologic causes, the presence of a predominantly ...

journal_title：Digestive diseases and sciences

authors： Soergel KH

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Barrett's esophagus (BE) is characterized by a distinct Th2-predominant cytokine profile. However, antigens that shift the immune response toward the Th2 profile are unknown. AIM:We examined the effects of rebamipide on the esophageal microbiome and BE development in a rat model. METHODS:BE was induced by ...

journal_title：Digestive diseases and sciences

authors： Kohata Y,Nakahara K,Tanigawa T,Yamagami H,Shiba M,Watanabe T,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2015-09-01 00:00:00

abstract：:The time-dependent appearance of phospholipase A2 (PLA2) activity in the preservation media of ischemic rat intestinal grafts is described. In controls, Ca2+-dependent, secretory PLA2 activity accumulated rapidly during the first 6 hr of ischemia, followed by a linear increase for up to 48 hr. LDH levels, by contrast,...

journal_title：Digestive diseases and sciences

authors： Sonnino RE,Pigatt L,Schrama A,Burchett S,Franson R

更新日期：1997-05-01 00:00:00

abstract：:Nonalcoholic steatohepatitis is the fastest-growing indication for the liver transplant and a leading cause of hepatocellular carcinoma among patients listed for liver transplantation in the USA. Post-transplant nonalcoholic hepatic steatosis and steatohepatitis are frequent complications of liver transplantation. Non...

journal_title：Digestive diseases and sciences

authors： Samji NS,Verma R,Keri KC,Singal AK,Ahmed A,Rinella M,Bernstein D,Abdelmalek MF,Satapathy SK

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The role of 5-aminosalicylic acid (5-ASA or mesalamine) in the prevention of colorectal cancer in ulcerative colitis (UC) patients was reported, but the effect on molecular targets in UC colon mucosa is unknown. AIM:This observational study evaluates gene expression levels of 5-ASA targets using serial colo...

journal_title：Digestive diseases and sciences

authors： Bajpai M,Seril DN,Van Gurp J,Geng X,Alvarez J,Minacapelli CD,Gorin S,Das KK,Poplin E,Cheng J,Amenta PS,Das KM

更新日期：2019-03-01 00:00:00

abstract：:We prospectively assessed the relationship between nodular gastritis and Helicobacter pylori infection. Of 1409 adults who underwent endoscopy for persistent dyspepsia between June 2004 and August 2005, 41 (2.9%) patients were diagnosed with nodular gastritis (11 [27%] men and 30 [73%] women). The mean age was 45.9 ye...

journal_title：Digestive diseases and sciences

authors： Chen MJ,Wang TE,Chang WH,Liao TC,Lin CC,Shih SC

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:It is not known if genetic background, characteristics at diagnosis, physical and psychological well-being, and adherence to a gluten-free diet are comparable between patients with familial or sporadic celiac disease. These issues were investigated in a follow-up study. METHODS:Altogether 1064 patients were...

journal_title：Digestive diseases and sciences

authors： Airaksinen L,Myllymäki L,Kaukinen K,Saavalainen P,Huhtala H,Lindfors K,Kurppa K

更新日期：2020-07-23 00:00:00

abstract：BACKGROUND:Preclinical data demonstrate that activation of the renin-angiotensin system (RAS) contributes to mucosal inflammation, and RAS inhibition by angiotensin-converting-enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improves colitis in animal models. Less is known regarding the effects of RAS i...

journal_title：Digestive diseases and sciences

authors： Jacobs JD,Wagner T,Gulotta G,Liao C,Li YC,Bissonnette M,Pekow J

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:Postoperative infection is not uncommon after hepatectomy. This study assessed the effectiveness of preoperative antibiotic prophylaxis in elective hepatectomy in a randomized clinical trial setting. METHODS:A total of 120 patients who were scheduled to undergo elective hepatectomy were equally rand...

journal_title：Digestive diseases and sciences

authors： Zhou YM,Chen ZY,Li XD,Xu DH,Su X,Li B

更新日期：2016-06-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) as an indication to liver transplant (LT) started as palliative treatment, then moved to potentially curative anti-cancer therapy and more recently entered the era of competition with non-cancer indications, consequent to the need of the society to target equal distribution of the limite...

journal_title：Digestive diseases and sciences

authors： Sposito C,Cucchetti A,Mazzaferro V

更新日期：2019-04-01 00:00:00