Human cholecystokinin-A receptor is not an oncofetal protein.

abstract：:Aging and gastrointestinal malignancies, including that of the stomach are associated with increased activation of EGF-receptor (EGFR). Although the intracellular events that regulate this process are poorly understood, we hypothesize that loss of ERRP (EGFR-related protein; GenBank accession number AF187818), a recen...

journal_title：Digestive diseases and sciences

authors： Majumdar AP,Du J,Hatfield JS,Levi E,Adsay V,Schmelz EM,Nagothu KK,Jaszewski R,Kucuk O,Sarkar FH

更新日期：2003-05-01 00:00:00

abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...

journal_title：Digestive diseases and sciences

authors： Yuki N,Hayashi N,Kasahara A,Hagiwara H,Katayama K,Fusamoto H,Kamada T

更新日期：1992-01-01 00:00:00

abstract：:Four patients with cold urticaria and six control subjects were studied. Gastric acid output was measured for 1 hr before and 1 hr after the immersion of both hands in ice cold water. The mean acid output fell in the control group by 16.3%. Acid output in the cold urticaria patients rose in each case following the col...

journal_title：Digestive diseases and sciences

authors： Lass N,Doron O,Gilat T

更新日期：1980-07-01 00:00:00

abstract：:A large retrospective autopsy study of patients was analyzed to evaluate the major etiologic and pathologic factors contributing to fatal acute pancreatitis (AP). From an autopsy population of 50,227 patients, 405 cases were identified where AP was defined as the official primary cause of death. AP was classified acco...

journal_title：Digestive diseases and sciences

authors： Renner IG,Savage WT 3rd,Pantoja JL,Renner VJ

更新日期：1985-10-01 00:00:00

abstract：:Left-sided portal hypertension is a rare clinical syndrome which may lead to bleeding from isolated gastric varices. Pancreatic disease is the most common etiology. Left-sided portal hypertension should be considered in the presence of gastrointestinal bleeding with normal liver function and unexplained splenomegaly. ...

journal_title：Digestive diseases and sciences

authors： Köklü S,Coban S,Yüksel O,Arhan M

更新日期：2007-05-01 00:00:00

abstract：:All cases of hepatolithiasis showed features of chronic proliferative cholangitis, and it has been speculated that the atypical glandular proliferation might be a precursor to overt cholangiocarcinoma. Proliferative cell nuclear antigen (PCNA) is a nuclear protein synthesized in the G1/S phase of the cell cycle and th...

journal_title：Digestive diseases and sciences

authors： Lee KT,Sheen PC

更新日期：1999-11-01 00:00:00

abstract：:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

journal_title：Digestive diseases and sciences

authors： Guslandi M,Mezzi G,Sorghi M,Testoni PA

更新日期：2000-07-01 00:00:00

abstract：AIM:Although Ebola virus infection (EVI) clinically presents with common, prominent, gastroenterologic manifestations, this subject has not been previously reviewed. This work critically and comprehensively reviews this subject. METHODS:This study is a comprehensive literature review generated by computerized search o...

journal_title：Digestive diseases and sciences

authors： Sharma N,Cappell MS

更新日期：2015-09-01 00:00:00

abstract：:Opioids, both endogenous and exogenous, have been shown to exert a modulating influence on many gastrointestinal functions. Animal studies suggest an inhibitory role for opioids in the control of pancreatic secretion, which may be exerted through their inhibitory effect on acetylcholine release from intramural neurons...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Saad C,Valenzuela JE

更新日期：1988-05-01 00:00:00

abstract：:The major host defense mechanisms against bacterial overgrowth in the small bowel are the normal propulsive activity of the bowel itself and gastric acid secretion. Microbial interactions are a major factor in regulating the indigenous bacterial flora. Studies of the bacterial enzymes of the gut suggest that changes i...

journal_title：Digestive diseases and sciences

authors： Simon GL,Gorbach SL

更新日期：1986-09-01 00:00:00

abstract：:This article [1] is retracted at the request of Editor-in-Chief. ...

journal_title：Digestive diseases and sciences

authors： Zong G,Xu Z,Zhang S,Shen Y,Qiu H,Zhu G,He S,Tao T,Chen X

更新日期：2019-11-11 00:00:00

abstract：:We previously demonstrated that false-positive findings for tumor markers are frequently observed, and that the sensitivity of marker monitoring for early detection of the recurrence is low after curative resection of gastric cancer. The aim of this study was to investigate whether such characters are specific to gast...

journal_title：Digestive diseases and sciences

authors： Ohtsuka T,Nakafusa Y,Sato S,Kitajima Y,Tanaka M,Miyazaki K

更新日期：2008-06-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) as an indication to liver transplant (LT) started as palliative treatment, then moved to potentially curative anti-cancer therapy and more recently entered the era of competition with non-cancer indications, consequent to the need of the society to target equal distribution of the limite...

journal_title：Digestive diseases and sciences

authors： Sposito C,Cucchetti A,Mazzaferro V

更新日期：2019-04-01 00:00:00

abstract：:A patient with congenital asucrasia was investigated using in vivo differential urinary disaccharide excretion. Impaired hydrolysis of sucrose and isomaltose, but normal lactase activity, were demonstrated and confirmed by in vitro estimation. The technique of differential disaccharide excretion can now be used to ass...

journal_title：Digestive diseases and sciences

authors： Maxton DG,Catt SD,Menzies IS

更新日期：1989-01-01 00:00:00

abstract：:To date few therapies have been shown to reliably prevent the evolution of Crohn's disease (CD). The traditional Chinese medicine, Tripterygium wilfordii Hook F (TWHF), has both immunomodulatory and anti-inflammatory activities. Our aim was to investigate the potential efficacy of T2, the major constituent of extracts...

journal_title：Digestive diseases and sciences

authors： Ren J,Tao Q,Wang X,Wang Z,Li J

更新日期：2007-08-01 00:00:00

abstract：:The effects of somatostatin on diarrhea and on small intestinal flow of water and electrolytes (slow-marker perfusion technique) in a patient with pancreatic cholera are reported. Continuous intravenous infusion of somatostatin (8 micrograms/kg/hr) suppressed the diarrhea, but a rebound was observed after somatostatin...

journal_title：Digestive diseases and sciences

authors： Ruskoné A,René E,Chayvialle JA,Bonin N,Pignal F,Kremer M,Bonfils S,Rambaud JC

更新日期：1982-05-01 00:00:00

abstract：:One hundred nineteen children, either French or from the Ivory Coast, aged 1-8 years, were submitted to pancreatic function testing by duodenal aspiration. Trypsin, chymotrypsin, lipase, phospholipase, amylase, volume, bicarbonate, chloride, and calcium were estimated before and after an intravenous injection of 1 CU ...

journal_title：Digestive diseases and sciences

authors： Sauniere JF,Sarles H,Attia Y,Lombardo A,Yoman TN,Laugier R,Manlan K,Sahel J

更新日期：1986-05-01 00:00:00

abstract：:The presence in the esophagus of three distinct entities--Barrett's mucosa, Crohn's disease, and adenocarcinoma--is a very rare finding. In a 60-year-old man with a long history of heartburn and recently developed dysphagia, narrowing of the distal esophagus was found to be related to the presence of Barrett's mucosa....

journal_title：Digestive diseases and sciences

authors： Delpre G,Mor C,Avidor I,Gutman H,Leisser A,Kott I,Kadish U

更新日期：1989-02-01 00:00:00

abstract：:Despite many studies on pain of functional gastrointestinal disorders (FGID), the pain mechanism of FGID is not well understood, and pain treatment of FGID is not established. Following our former functional dyspepsia (FD) study, we proposed two subgroups of patients with irritable bowel syndrome (IBS), pain and disco...

journal_title：Digestive diseases and sciences

authors： Handa M,Nukina H,Ando K,Kubo C

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and diabetes are risk factors for advanced alcoholic liver disease, and both are components of the metabolic syndrome. We aimed to assess the prevalence of metabolic syndrome and its components in a contemporary US cohort of adults with alcoholic liver disease and compare it to a historic co...

journal_title：Digestive diseases and sciences

authors： Singh A,Amin H,Garg R,Gupta M,Lopez R,Alkhouri N,MCCullough A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Preclinical data demonstrate that activation of the renin-angiotensin system (RAS) contributes to mucosal inflammation, and RAS inhibition by angiotensin-converting-enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improves colitis in animal models. Less is known regarding the effects of RAS i...

journal_title：Digestive diseases and sciences

authors： Jacobs JD,Wagner T,Gulotta G,Liao C,Li YC,Bissonnette M,Pekow J

更新日期：2019-07-01 00:00:00

abstract：:For biotherapeutic agents, there is a lack of information on dose-response relationships and mechanism of action. The present study was designed to address these issues for Saccharomyces boulardii using the rat model of castor oil-induced diarrhea. A single dose of Saccharomyces boulardii at 12 x 10(10) CFU/kg of viab...

journal_title：Digestive diseases and sciences

authors： Girard P,Pansart Y,Lorette I,Gillardin JM

更新日期：2003-04-01 00:00:00

abstract：:The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner's glands was investigated in rats. Secretin increased volume secretion and the median output of EGF rose from 720 fmol/5 hr (total range 460-1320) in controls to 2065 fmol/5 hr (total range 1560-2730) at a dose of 50 pmo...

journal_title：Digestive diseases and sciences

authors： Olsen PS,Kirkegaard P,Poulsen SS,Nexø E

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a common malignancy worldwide with poor outcomes. Therefore, it is important to identify a valuable prognostic biomarker for HCC. The present study aimed to identify novel prognostic biomarkers for HCC and evaluate the potential role of hub genes in HCC. METHODS:Weighted ge...

journal_title：Digestive diseases and sciences

authors： Wu M,Jiang L

更新日期：2021-01-26 00:00:00

abstract：:To evaluate the frequency and type of gastroduodenal mucosal inflammatory changes in patients with symptomatic acid peptic disease and nonulcer dyspepsia, 100 patients with gastrointestinal symptoms indicative of acid peptic disease or dyspepsia and 10 control subjects were clinically evaluated and underwent radiograp...

journal_title：Digestive diseases and sciences

authors： Greenlaw R,Sheahan DG,DeLuca V,Miller D,Myerson D,Myerson P

更新日期：1980-09-01 00:00:00

abstract：:The effects of vasoactive intestinal polypeptide (VIP), glucagon, and secretin on lower esophageal sphincter pressure were investigated in awake baboons. The three hormones were compared with respect to effect on (1) resting lower esophageal sphincter pressure and (2) maximal stimulatory response to pentagastrin. VIP ...

journal_title：Digestive diseases and sciences

authors： Siegel SR,Brown FC,Castell DO,Johnson LF,Said SI

更新日期：1979-05-01 00:00:00

abstract：INTRODUCTION:Stent placement in the distal duodenum can be difficult. We describe a case report of a 94-year-old man with metastatic pancreatic head cancer compressing the third and fourth portions of the duodenum, treated by endoscopic stent placement using a colonoscope. AREAS COVERED:A literature review highlighted...

journal_title：Digestive diseases and sciences

authors： Minervini A,Lauro A,Pagano N,Vaccari S,D'Andrea V,Marino IR,Cervellera M,Tonini V

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:S-isomer (S) pantoprazole is known to be more effective and less dependent on cytochrome 2C19 than R-isomer (R)-pantoprazole. AIM:The purpose of this study was to compare the efficacy and safety of S-pantoprazole 20 mg versus pantoprazole 40 mg for treatment of reflux esophagitis. METHODS:This multi-center...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Bak YT,Rhee PL,Kim SG,Jung HY,Seol SY

更新日期：2012-12-01 00:00:00

abstract：:We report a case of documented transient segmental aperistalsis of the distal esophagus following an accidental electrical injury. There are no other reports in the literature demonstrating this phenomenon. A review of gastrointestinal injury secondary to electrical injury is presented. ...

journal_title：Digestive diseases and sciences

authors： Rubin BM,Doman DB,Goldberg HJ,Golding MI

更新日期：1998-09-01 00:00:00

abstract：:Modafinil may be a potentially effective treatment for primary biliary cirrhosis (PBC)-related fatigue. About 42 patients were given a 3-day trial of 100-200 mg modafinil. Response was defined as increased energy, decreased somnolence and sleep requirements, and improved daily function. Patients with positive response...

journal_title：Digestive diseases and sciences

authors： Ian Gan S,de Jongh M,Kaplan MM

更新日期：2009-10-01 00:00:00