Diversity of nucleotide sequences in hypervariable region 1 of hepatitis C virus in Japanese patients with chronic hepatitis C of unknown mode of transmission.

abstract：:In view of the increased anticoagulant effect of acetaldehyde-treated heparin, other glycosaminoglycans (GAGs) such as chondroitin sulfates A and C, dermatan sulfate (chondroitin sulfate B), heparan sulfate, and hyaluronic acid were tested for anticoagulant activity before and after exposure to acetaldehyde. Clotting ...

journal_title：Digestive diseases and sciences

authors： Brecher AS,Adamu MT

更新日期：2001-09-01 00:00:00

abstract：:The diagnostic accuracy of two different methods of sectioning rectal biopsies was evaluated prospectively. The frequency of focal and diffuse findings in more than 80 serial sections from a limited portion of the well-oriented areas of 74 biopsies was compared with that found in three or more step sections distribute...

journal_title：Digestive diseases and sciences

authors： Surawicz CM

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Gastric acidification inhibits motilin-induced gastric phase III contractions. However, the underlying mechanism has not been thoroughly investigated. Here, we studied the inhibitory mechanism by gastric acidification on motilin-induced contraction in Suncus murinus (S. murinus). METHODS:We measured interdi...

journal_title：Digestive diseases and sciences

authors： Yoshimura M,Mikami T,Kuroda K,Nishida M,Ito K,Mondal A,Koyama K,Jogahara T,Sakata I,Sakai T

更新日期：2016-06-01 00:00:00

abstract：:The purpose of this study was to investigate interdigestive cycling and postprandial release of pancreatic polypeptide (PP) in relation to exocrine pancreatic function in chronic pancreatitis (CP). We investigated nine patients with mild-moderate CP (MCP), eight patients with severe CP and steathorrea (SCP), and 17 he...

journal_title：Digestive diseases and sciences

authors： Pieramico O,Nelson DK,Glasbrenner B,Malfertheiner P

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:We explored the function of the intestine's mucosal barrier to foreign antigen entry in Crohn's disease. Macroscopically and microscopically uninvolved areas of the small intestines of patients with Crohn's disease were examined. We studied 27 endoscopic biopsy samples from 17 patients with Crohn's disease and 14 samp...

journal_title：Digestive diseases and sciences

authors： Malin M,Isolauri E,Pikkarainen P,Karikoski R,Isolauri J

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and diabetes are risk factors for advanced alcoholic liver disease, and both are components of the metabolic syndrome. We aimed to assess the prevalence of metabolic syndrome and its components in a contemporary US cohort of adults with alcoholic liver disease and compare it to a historic co...

journal_title：Digestive diseases and sciences

authors： Singh A,Amin H,Garg R,Gupta M,Lopez R,Alkhouri N,MCCullough A

更新日期：2020-11-01 00:00:00

abstract：:Biliary mucin was isolated from human hepatic bile, and its induced effects on the appearance time of cholesterol monohydrate crystals (nucleation time) and on the precipitation of calcium carbonate were studied in vitro to examine the possible significance of mucin for ductular gallstone formation. Mucin was isolated...

journal_title：Digestive diseases and sciences

authors： Yamasaki T,Chijiiwa K,Endo M

更新日期：1993-05-01 00:00:00

abstract：:A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4 g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients, 44 of whom received 5-ASA and 42 received hydrocortisone. The results were favorable in terms of clinical, s...

journal_title：Digestive diseases and sciences

authors： Campieri M,Gionchetti P,Belluzzi A,Brignola C,Migaldi M,Tabanelli GM,Bazzocchi G,Miglioli M,Barbara L

更新日期：1987-12-01 00:00:00

abstract：:The clonality of gastric glands remains a controversial topic. Chimeric mouse studies suggested that all gastric glands were monoclonal. However, using the X-linked transgenic mouse model, we have suggested that most glands are polyclonal during development and that the fraction of monoclonal glands increases after bi...

journal_title：Digestive diseases and sciences

authors： Nomura S,Kaminishi M,Takagi N,Esumi H

更新日期：2004-02-01 00:00:00

abstract：:Verapamil, a type-1 calcium-channel blocker, given intraperitoneally, macroscopically protected the gastric mucosa of rats from 96% ethanol-induced lesions in a dose-dependent fashion. This effect was significant when verapamil at 10 or 20 mg/kg was given 1 hr before ethanol. Histopathologically, verapamil prevented t...

journal_title：Digestive diseases and sciences

authors： Gutiérrez-Cabano CA

更新日期：1993-11-01 00:00:00

abstract：:The hepatic stimulatory substance (HSS) extracted from weanling rat livers was purified 381,000-fold using chromatographic techniques including nondissociating polyacrylamide gel electrophoresis (nondenaturing PAGE). The activity of this highly purified HSS, named Acr-F4, was assessed in two in vivo models. In 40% hep...

journal_title：Digestive diseases and sciences

authors： Francavilla A,Barone M,Van Thiel DH,Mazzaferro V,Prelich JG,Starzl TE

更新日期：1991-05-01 00:00:00

abstract：:We postulated that coadministration of cholylsarcosine with ursodeoxycholic acid might provide additional benefit to primary biliary cirrhosis patients with an incomplete response to ursodeoxycholic acid. Our aim was to test the tolerability and the effect of adjuvant cholylsarcosine on liver tests and plasma choleste...

journal_title：Digestive diseases and sciences

authors： Ricci P,Hofmann AF,Hagey LR,Jorgensen RA,Rolland Dickson E,Lindor KD

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

journal_title：Digestive diseases and sciences

authors： Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

更新日期：2013-05-01 00:00:00

abstract：:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

journal_title：Digestive diseases and sciences

authors： Guslandi M,Mezzi G,Sorghi M,Testoni PA

更新日期：2000-07-01 00:00:00

abstract：:Stevens-Johnson Syndrome (SJS) is a rare but severe dermatological condition that typically occurs after the ingestion of medications such as nonsteroidal drugs, antibiotics, and anticonvulsants. Extracutaneous manifestations of the syndrome can occur and may involve the conjunctiva, trachea, buccal mucosa, gastrointe...

journal_title：Digestive diseases and sciences

authors： Morelli MS,O'Brien FX

更新日期：2001-11-01 00:00:00

abstract：:This study was undertaken to compare the effects of subtotal Billroth II gastrectomy on gastric emptying and gastrointestinal motility with previously published results in intact dogs and in dogs with subtotal Roux-Y gastrectomy. Extraluminal strain gauge transducers were used to study gastrointestinal motility after ...

journal_title：Digestive diseases and sciences

authors： Ehrlein HJ,Wulschke S,Thoma G,Schumpelick V

更新日期：1989-08-01 00:00:00

abstract：:The mechanisms by which Dai-kenchu-to (TJ-100), a kampo medicine, enhances gastrointestinal motility was investigated using isolated guinea pig ileum. TJ-100 induced contractions accompanied by autonomous contraction at a concentration of more than 3 x 10(-4) g/ml in a dose-related manner. The TJ-100-induced ileal con...

journal_title：Digestive diseases and sciences

authors： Satoh K,Hayakawa T,Kase Y,Ishige A,Sasaki H,Nishikawa S,Kurosawa S,Yakabi K,Nakamura T

更新日期：2001-02-01 00:00:00

abstract：:In previous open studies, misoprostol and metronidazole reduced nonsteroidal anti-inflammatory drug-induced intestinal permeability changes and inflammation respectively. We assessed the effects of indomethacin treatment (50 mg three times a day) for one week with either coadministered metronidazole (400 mg twice a da...

journal_title：Digestive diseases and sciences

authors： Davies GR,Wilkie ME,Rampton DS

更新日期：1993-03-01 00:00:00

abstract：:Obesity and diet affect the incidence and severity of various types of cancer, including colon cancer. It is not known whether obesity, independent of diet, is a risk factor for colon adenocarcinoma. We used azoxymethane (AOM) to induce colon cancer in mature genetically obese male Zucker rats (fa/fa) on low-fat crude...

journal_title：Digestive diseases and sciences

authors： Weber RV,Stein DE,Scholes J,Kral JG

更新日期：2000-05-01 00:00:00

abstract：:We report the findings in two sisters with active cirrhosis and an anti-liver-kidney microsomal antibody (anti-LKM) of the autoimmune type. This unusual disease is characterized by the presence of high levels of antibodies that react with the smooth and rough endoplasmic reticulum of the liver and other tissues. Our p...

journal_title：Digestive diseases and sciences

authors： Buffet C,Homberg JC,Pelletier G,Turner K,Etienne JP

更新日期：1986-11-01 00:00:00

abstract：:We conducted a double-blind, placebo-controlled study to evaluate the effects of ranitidine on intragastric pH and upper gastrointestinal tract bleeding in severe head injury patients. Within 24 hr of the precipitating trauma, 34 adults with Glasgow coma scale scores < or = 10 were randomized to a 6.25 mg/hr ranitidin...

journal_title：Digestive diseases and sciences

authors： Burgess P,Larson GM,Davidson P,Brown J,Metz CA

更新日期：1995-03-01 00:00:00

abstract：:Symptom scores, stool data, and the transit of a standard, solid meal were measured in 28 patients with irritable bowel syndrome (IBS) during baseline conditions and after five weeks of treatment with placebo and loperamide, given as a flexible dosage regime in the form of a double-blind, cross-over trial. All patient...

journal_title：Digestive diseases and sciences

authors： Cann PA,Read NW,Holdsworth CD,Barends D

更新日期：1984-03-01 00:00:00

abstract：:Ischemic enterocolitis is a well-recognized entity occurring in cocaine users. Diagnosis is based on the presence of rectal bleeding, abdominal pain, a history of cocaine use, supportive endoscopic and histopathologic findings, and the absence of other etiologic mechanisms of ischemic colitis. In this study, we evalua...

journal_title：Digestive diseases and sciences

authors： Niazi M,Kondru A,Levy J,Bloom AA

更新日期：1997-07-01 00:00:00

abstract：:The paraoxonase (PON) genes family maps to chromosome 7q21-q22, within a loci that also showed evidence of susceptibility genes for both Crohn's disease (CD) and ulcerative colitis (UC). In this case-control study we investigated the possible relationship between PON1 and PON2 polymorphisms and the risk of inflammator...

journal_title：Digestive diseases and sciences

authors： Karban A,Hartman C,Eliakim R,Waterman M,Nesher S,Barnett-Griness O,Shamir R

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The influence of direct-acting antivirals (DAAs) on chronic hepatitis C (CHC)-related hepatocellular carcinoma (HCC) remains controversial. We investigated the effect of eradicating CHC using DAAs on treatment outcomes in patients with CHC-related HCC treated with transarterial chemoembolization (TA...

journal_title：Digestive diseases and sciences

authors： Hyun HK,Cho EJ,Park SY,Hong YM,Kim SS,Kim HY,Heo NY,Park JG,Sinn DH,Kang W,Jeong SW,Song MJ,Park H,Lee D,Lee YS,Cho SB,An CS,Rhee HJ,Lee HW,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Lee JH,Yu SJ,Kim YJ,Yoo

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:The gut is an important target organ of injury during critically ill conditions. Although Gram staining is a common and quick method for identifying bacteria, its clinical application has not been fully evaluated in critically ill conditions. AIMS:This study's aims were to identify patterns of Gram-stained ...

journal_title：Digestive diseases and sciences

authors： Shimizu K,Ogura H,Tomono K,Tasaki O,Asahara T,Nomoto K,Morotomi M,Matsushima A,Nakahori Y,Yamano S,Osuka A,Kuwagata Y,Sugimoto H

更新日期：2011-06-01 00:00:00

abstract：:A multitude of opportunistic infections has been documented in virtually every organ system of patients with the acquired immunodeficiency syndrome (AIDS). Prominent among these are infections of the gastrointestinal tract. However, studies of large numbers of patients documenting the frequency of such involvement are...

journal_title：Digestive diseases and sciences

authors： Antony MA,Brandt LJ,Klein RS,Bernstein LH

更新日期：1988-09-01 00:00:00

abstract：:Rectally administered suspensions of 5-aminosalicylic acid (5-ASA) are topically effective in treating left-sided ulcerative colitis. The extent to which the contents of these enemas are distributed to inflamed mucosal linings has not previously been determined. This study was undertaken to validate a technique for la...

journal_title：Digestive diseases and sciences

authors： Vitti RA,Meyers F,Knight LC,Siegel JA,Malmud LS,Fisher RS

更新日期：1989-11-01 00:00:00

abstract：:Concentration and voltage dependence of unidirectional Mg fluxes across the rat colon ascendens were measured in a modified Ussing chamber. Mucosa (M) to serosa (S) Mg flux exhibits a cellular component, whereas SM flux is totally diffusive. At all the concentrations between 0.125 and 8 mmol/liter MS Mg transport is h...

journal_title：Digestive diseases and sciences

authors： Karbach U

更新日期：1989-12-01 00:00:00