Enhanced absorption of macromolecules. A secondary factor in Crohn's disease.

abstract：:The role of HBV precore mutations in the spontaneous reactivation of chronic hepatitis B (CHB) is currently unknown. We studied 10 patients with CHB; five were HBeAg+ (group I) and five were anti-HBe+ (group II). All 10 had spontaneous reactivation of CHB as defined by the appearance of clinical symptoms along with an...

journal_title：Digestive diseases and sciences

authors： Laskus T,Rakela J,Tong MJ,Persing DH

更新日期：1994-09-01 00:00:00

abstract：:Since celiac disease screening by traditional IgA anti-endomysial antibody test is limited by high costs of monkey esophagus commercial kits as well as by rising ethical problems related to the endangered species, the identification of an inexpensive and commonly available substrate for this antibody determination is ...

journal_title：Digestive diseases and sciences

authors： Volta U,Molinaro N,de Franceschi L,Fratangelo D,Bianchi FB

更新日期：1995-09-01 00:00:00

abstract：:Pancreatic-type isoamylase (P-type) and salivary-type isoamylase (S-type) activities were determined by the wheat protein inhibitor method in 29 patients with end-stage renal disease and in 38 healthy volunteers. Serum levels of total amylase (322 +/- 43 units/liter) and P-type (212 +/- 39 units/liter) in ESRD were si...

journal_title：Digestive diseases and sciences

authors： Araki T,Ueda M,Taketa K,Kosaka K

更新日期：1989-09-01 00:00:00

abstract：:The purpose of this study was to establish if estrogen-induced hepatocyte proliferation in vitro involves the cell cycle regulators cyclin D1, p21(Cip1), and p27(Kip1). Male rat hepatocytes were cultured in presence of 17-beta-estradiol (E2) +/- ICI-182780, a pure estrogen antagonist, and [3H]-thymidine, as required. ...

journal_title：Digestive diseases and sciences

authors： Barone M,Ladisa R,Di Leo A,Spano D,Francioso D,Aglio V,Amoruso A,Francavilla A,Iolascon A

更新日期：2006-03-01 00:00:00

abstract：:Sumatriptan, a 5-HT1-receptor agonist has been shown to delay gastric emptying of liquids and solids in humans. However, no data are available of the effect of sumatriptan on gastric adaptation after distension with liquids and on symptoms induced by gastric distension. In 23 normal subjects and 30 dyspeptic patients ...

journal_title：Digestive diseases and sciences

authors： Malatesta MG,Fascetti E,Ciccaglione AF,Cappello G,Grossi L,Ferri A,Marzio L

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:An increasing number of studies have found that long non-coding RNAs (lncRNAs) play an important role in carcinogenesis and tumor progression, whereas their molecular mechanisms of function remain largely unknown. AIMS:This study was aimed to explore the biological function and underlying mechanism of a new...

journal_title：Digestive diseases and sciences

authors： He W,Zhang D,Li D,Zhu D,Geng Y,Wang Q,He J,Wu J

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin in AH is unknown. AIMS:To investigate the association between my...

journal_title：Digestive diseases and sciences

authors： Shamseddeen H,Madathanapalli A,Are VS,Shah VH,Sanyal AJ,Tang Q,Liang T,Gelow K,Zimmers TA,Chalasani N,Desai AP

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Use of ultrathin (ut) endoscopes is sometimes limited by their design (outer diameter, tip angulation and image quality). New ut-endoscopes are being designed to address these limitations. A new ut-endoscope, XGIF-PV70N5 (Olympus America Inc.), with an outer diameter of 5.5 mm, 4-way angulatio...

journal_title：Digestive diseases and sciences

authors： Agrawal D,Wong RC,Isenberg G,Faulx A,Chak A

更新日期：2011-03-01 00:00:00

abstract：:Health-care-seeking behaviors related to bowel complaints may vary between ethnic groups. A survey of a nonpatient population in El Paso, Texas, was conducted in order to examine differences in health care behavior related to bowel dysfunction, and in the perception of health and bowel function, in Hispanics and non-H...

journal_title：Digestive diseases and sciences

authors： Zuckerman MJ,Guerra LG,Drossman DA,Foland JA,Gregory GG

更新日期：1996-01-01 00:00:00

abstract：:In a Caucasian woman with a history of ocular and pulmonary sarcoidosis, the occurrence of sclerosing peritonitis with exudative ascites but without any of the well-known causes of this syndrome prompts us to consider that sclerosing peritonitis is a manifestation of sarcoidosis. The dramatic improvement that occurred...

journal_title：Digestive diseases and sciences

authors： Ngô Y,Messing B,Marteau P,Nouël O,Pasquiou A,Lavergne A,Rambaud JC

更新日期：1992-11-01 00:00:00

abstract：:Ethanol is a common cause of both acute and chronic pancreatitis. Studies in other organs suggest that polymorphonuclear neutrophils activated by ethanol may cause tissue injury in a variety of conditions. The aim of this study was to investigate the effects of ethanol on neutrophil extravasation in the feline pancrea...

journal_title：Digestive diseases and sciences

authors： Reber PU,Lewis MP,Patel AG,Andren-Sandberg A,Ashley SW,Reber HA

更新日期：1998-12-01 00:00:00

abstract：:Rabeprazole achieves more potent acid suppression than other proton pump inhibitors. Therefore it is administered at reduced as well as high dosages in eradication therapy for Helicobacter pylori; however, there is incomplete assessment of the efficacy of a reduced dosage of rabeprazole as might be employed in therapy...

journal_title：Digestive diseases and sciences

authors： Shimatani T,Inoue M,Kuroiwa T,Xu J,Tazuma S,Horikawa Y,Nakamura M

更新日期：2005-07-01 00:00:00

abstract：:The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All ...

journal_title：Digestive diseases and sciences

authors： Petroni ML,Jazrawi RP,Grundy A,Lanzini A,Pigozzi MG,Biasio A,Heaton KW,Virjee J,Northfield TC

更新日期：1995-09-01 00:00:00

abstract：INTRODUCTION:The C-31G polymorphism in the survivin promoter could de-repress the cell-cycle-dependent transcription of the human survivin gene, resulting in overexpression of survivin. This survivin mutation has only been studied on cervical carcinoma. However, no study has ever been conducted to evaluate the effect o...

journal_title：Digestive diseases and sciences

authors： Yang L,Zhu H,Zhou B,Gu H,Yan H,Tang N,Dong H,Sun Q,Cong R,Chen G,Wang B

更新日期：2009-05-01 00:00:00

abstract：:It is unknown whether demography, gallbladder function, or the radiographic appearance of gallstones predispose them to cause symptoms. We investigated these features in a consecutive series of 260 patients with newly diagnosed, uncomplicated gallstone disease, of whom 146 had experienced biliary pain and 114 were asy...

journal_title：Digestive diseases and sciences

authors： Ros E,Valderrama R,Bru C,Bianchi L,Terés J

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:To date, there are no studies reporting an association between vitamin D and Barrett's esophagus (BE), the precursor for esophageal adenocarcinoma (EAC). AIMS:Our aim was to study the association between serum 25-hydroxyvitamin D (25(OH)D) levels and prevalence and incidence of dysplasia/EAC in BE. METHODS...

journal_title：Digestive diseases and sciences

authors： Thota PN,Kistangari G,Singh P,Cummings L,Hajifathalian K,Lopez R,Sanaka MR

更新日期：2016-01-01 00:00:00

abstract：:Recombinant fibroblast growth factors (FGFs) maintain the integrity of the gut epithelium and reduce mucosal injury in experimental inflammatory bowel disease (IBD). Chemically synthesized FGF mimetics could potentially extend the utility of FGFs by tailoring them for optimal bioactivity and oral administration, for e...

journal_title：Digestive diseases and sciences

authors： Lin X,Zamora PO,Takahashi K,Lui Y

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Treatment with tumor necrosis factor-α (TNF-α) inhibitors in patients with Crohn's disease (CD) is associated with potentially serious infections, including tuberculosis (TB) and hepatitis B virus (HBV). We assessed the cost-effectiveness of extensive TB screening and HBV screening prior to initiati...

journal_title：Digestive diseases and sciences

authors： van der Have M,Oldenburg B,Fidder HH,Belderbos TD,Siersema PD,van Oijen MG

更新日期：2014-03-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly morbid and prevalent cancer globally. While high quality evidence for mortality benefit of HCC surveillance is lacking, early detection of HCC is likely beneficial as prognosis is highly correlated with tumor stage. High risk populations, including patients with cirrhosis and...

journal_title：Digestive diseases and sciences

authors： Deng LX,Mehta N

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The arrival of tacrolimus has drastically improved AALDLT recipients' survival. However, little data of tacrolimus have been reported concerning its effects on lipid metabolism for AALDLT recipients. AIM:Out aim was to investigate the relationship between tacrolimus blood concentration and lipid metabolism ...

journal_title：Digestive diseases and sciences

authors： Li HY,Li B,Wei YG,Yan LN,Wen TF,Zhao JC,Xu MQ,Wang WT,Ma YK,Yang JY

更新日期：2012-01-01 00:00:00

abstract：:Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supplemented with 0.2% DOC, develop colonic inflammation associated with in...

journal_title：Digestive diseases and sciences

authors： Bernstein H,Holubec H,Bernstein C,Ignatenko NA,Gerner E,Dvorak K,Besselsen D,Blohm-Mangone KA,Padilla-Torres J,Dvorakova B,Garewal H,Payne CM

更新日期：2007-03-01 00:00:00

abstract：:Serum and urine concentrations of pancreatic polypeptide (PP) were measured during experimental acute hemorrhagic pancreatitis and small-bowel infarction in dogs. The mean serum PP concentration in animals with pancreatitis increased markedly after 1 hr and remained elevated, while the mean serum PP concentration in t...

journal_title：Digestive diseases and sciences

authors： Pappas TN,Yovos JG,Ellison EC,O'Dorisio TM,Cataland S,Pace WG,Carey LC

更新日期：1981-11-01 00:00:00

abstract：:In enriched canine parietal cell preparations, misoprostol, an analog of prostaglandin E1 methyl ester, was rapidly deesterified to misoprostol free acid. Under this circumstance, misoprostol and misoprostol free acid exhibited equal antisecretory potency against histamine-stimulated acid secretion and bound equally w...

journal_title：Digestive diseases and sciences

authors： Tsai BS,Kessler LK,Stolzenbach J,Schoenhard G,Bauer RF

更新日期：1991-05-01 00:00:00

abstract：:We studied effects of graded concentrations of intragastric calcium on acid secretion, residual gastric volume, and serum gastrin and calcium levels. Intragastric titration was performed with solutions of isotonic mannitol or mannitol plus 2.5, 6, 16, 39, and 97 mM CaCl(2) in 10 normal and eight duodenal ulcer subject...

journal_title：Digestive diseases and sciences

authors： Barclay G,Maxwell V,Grossman MI,Solomon TE

更新日期：1983-05-01 00:00:00

abstract：:Acid inhibition after proton pump inhibitors in children is variable, and to measure it by a noninvasive method may help to tailor treatment. To study gastric acid inhibition after a single dose of PPI, by measuring urinary acid output (UAO), which decreases as parietal cells release acid into the stomach during a mea...

journal_title：Digestive diseases and sciences

authors： Oderda G,Rapa A,Chiorboli E,Ronchi B,Zavallone A,Strigini L

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:The impact of prior anti-TNF use on "real-life" outcomes of adalimumab therapy in ulcerative colitis (UC) is not well known. AIM:To compare the influence of prior anti-TNF use on the outcomes of adalimumab maintenance treatment in UC patients. We also assessed the effectiveness of adalimumab dose escalation...

journal_title：Digestive diseases and sciences

authors： Taxonera C,Iglesias E,Muñoz F,Calvo M,Barreiro-de Acosta M,Busquets D,Calvet X,Rodríguez A,Pajares R,Gisbert JP,López-Serrano P,Pérez-Calle JL,Ponferrada Á,De la Coba C,Bermejo F,Chaparro M,Olivares D,Alba C,Fernández

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Much of the economic burden of Crohn's disease (CD) is related to surgery. Twenty percent of patients with CD have isolated colonic disease. While permanent end ileostomy (EI) is generally the procedure of choice for patients with refractory CD colitis, single-center experiences suggest that restorative proc...

journal_title：Digestive diseases and sciences

authors： Taleban S,Van Oijen MG,Vasiliauskas EA,Fleshner PR,Shen B,Ippoliti AF,Targan SR,Melmed GY

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Enhanced cell expression of MAdCAM-1 is critical in tissue recruitment of lymphocytes in response to stimuli expressing the α4β7 integrin. MAdCAM-1 is well characterized in gut mucosa with emerging evidence of hepatic expression. AIMS:(i) Compare quantitative/semi-quantitatively MAdCAM-1 expression in relat...

journal_title：Digestive diseases and sciences

authors： Ala A,Brown D,Khan K,Standish R,Odin JA,Fiel MI,Schiano TD,Hillan KJ,Rahman SA,Hodgson HJ,Dhillon AP

更新日期：2013-09-01 00:00:00

abstract：:The effects of ecabet sodium (ecabet), 12-sulfodehydroabietic acid monosodium salt, on gastric mucin biosynthesis in rat antrum were compared with those in the corpus. Intragastric administration of ecabet significantly increased [3H]glucosamine incorporation into antral mucin as well as into corpus mucin during five ...

journal_title：Digestive diseases and sciences

authors： Ichikawa T,Ishihara K,Hayashida H,Hiruma H,Saigenji K,Hotta K

更新日期：2000-03-01 00:00:00