Pancreatic-type hyperamylasemia in end-stage renal disease.

Abstract:

:Pancreatic-type isoamylase (P-type) and salivary-type isoamylase (S-type) activities were determined by the wheat protein inhibitor method in 29 patients with end-stage renal disease and in 38 healthy volunteers. Serum levels of total amylase (322 +/- 43 units/liter) and P-type (212 +/- 39 units/liter) in ESRD were significantly higher than those of controls (total: 142 +/- 7 units/liter, P less than 0.01; P-type: 52 +/- 4 units/liter, P less than 0.01). There was no significant difference between S-type activities in ESRD (110 +/- 16 units/liter) and in controls (90 +/- 6 units/liter). The ratios of amylase clearance to creatinine clearance (Cam/Ccr) and S-type clearance to creatinine clearance (Cs-amy/Ccr) rose significantly in ESRD(Cam/Ccr: 5.7 +/- 0.6%; Cs-amy/Ccr: 4.3 +/- 0.55%) compared to controls (Cam/Ccr: 3.2 +/- 0.24%, P less than 0.01; Cs-amy/Ccr: 2.1 +/- 0.17%, P less than 0.01). The ratio of P-type clearance to creatinine clearance (Cp-amy/Ccr) revealed no significant difference between ESRD (5.5 +/- 0.54%) and controls (5.6 +/- 0.42%). The renal excretion of P-type appeared to be more impaired than that of S-type in ESRD.

journal_name

Dig Dis Sci

authors

Araki T,Ueda M,Taketa K,Kosaka K

doi

10.1007/BF01538080

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

1425-7

issue

9

eissn

0163-2116

issn

1573-2568

journal_volume

34

pub_type

杂志文章
  • Changes in serum hepatitis C virus RNA titer and response to interferon therapy in patients with chronic hepatitis C.

    abstract::Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02090379

    authors: Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

    更新日期:1994-10-01 00:00:00

  • Prognosis of gastric carcinoma after curative surgery. A population-based study using multivariate crude and relative survival analysis.

    abstract::A population-based series of 246 gastric cancer patients operated for cure and who survived the postoperative phase was reviewed to determine prognostic factors after potentially curative treatment. The overall five-year observed survival rate was 34.8%, and the relative survival rate was 43.9%. Previous history of ga...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296435

    authors: Arveux P,Faivre J,Boutron MC,Piard F,Dusserre-Guion L,Monnet E,Hillon P

    更新日期:1992-05-01 00:00:00

  • Is obesity a risk factor for Crohn's disease?

    abstract:BACKGROUND:Obesity is associated with a proinflammatory state. AIM:To determine whether obesity at diagnosis is a risk factor for Crohn's disease vs. ulcerative colitis and also vs. community controls and whether there is a U-shaped relationship between body mass index at diagnosis and risk of Crohn's disease versus u...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-010-1541-6

    authors: Mendall MA,Gunasekera AV,John BJ,Kumar D

    更新日期:2011-03-01 00:00:00

  • Crohn's disease and adenocarcinoma of the bowel.

    abstract::We present six cases of cancer associated with Crohn's disease and stress the importance of the earlier age of onset than spontaneously arising small-bowel carcinoma, the long period of latency from the time of diagnosis of Crohn's disease to that of carcinoma, and the generally poor prognosis. We emphasize, furthermo...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01308045

    authors: Traube J,Simpson S,Riddell RH,Levin B,Kirsner JB

    更新日期:1980-12-01 00:00:00

  • Measurement of postprandial changes in urine acid output to detect changes of gastric acid secretion after proton pump inhibitors in children.

    abstract::Acid inhibition after proton pump inhibitors in children is variable, and to measure it by a noninvasive method may help to tailor treatment. To study gastric acid inhibition after a single dose of PPI, by measuring urinary acid output (UAO), which decreases as parietal cells release acid into the stomach during a mea...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1023/a:1016465116541

    authors: Oderda G,Rapa A,Chiorboli E,Ronchi B,Zavallone A,Strigini L

    更新日期:2002-08-01 00:00:00

  • Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis.

    abstract::Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-007-9848-7

    authors: Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

    更新日期:2008-01-01 00:00:00

  • Cost-effectiveness of chemoprevention with proton pump inhibitors in Barrett's esophagus.

    abstract:BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3186-3

    authors: Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

    更新日期:2014-06-01 00:00:00

  • An inter-observer agreement study of autofluorescence endoscopy in Barrett's esophagus among expert and non-expert endoscopists.

    abstract:BACKGROUND:Autofluorescence imaging (AFI), which is a "red flag" technique during Barrett's surveillance, is associated with significant false positive results. The aim of this study was to assess the inter-observer agreement (IOA) in identifying AFI-positive lesions and to assess the overall accuracy of AFI. METHODS:...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10620-012-2358-2

    authors: Mannath J,Subramanian V,Telakis E,Lau K,Ramappa V,Wireko M,Kaye PV,Ragunath K

    更新日期:2013-02-01 00:00:00

  • Changes in cell proliferation and differentiation of adult rat small intestine epithelium after adrenalectomy: kinetic, biochemical, and morphological studies.

    abstract::The effects of 10-day bilateral adrenalectomy on morphometry, proliferation, and apoptosis were determined in the small intestine of 3-month-old Sprague-Dawley rats. The activities of sucrase, lactase, and its respective mRNA, aminopeptidase N, and intestinal alkaline phosphatase were also evaluated. Adrenalectomy lea...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1010611228730

    authors: Foligne B,Aissaoui S,Senegas-Balas F,Cayuela C,Bernard P,Antoine JM,Balas D

    更新日期:2001-06-01 00:00:00

  • Adalimumab for Induction of Histological Remission in Moderately to Severely Active Ulcerative Colitis.

    abstract:BACKGROUND:Histological remission represents a target distinct from endoscopic healing in ulcerative colitis (UC) and seems a better predictor of clinical outcomes. AIMS:The aim of this study was to assess the ability of adalimumab to achieve histological remission in UC patients. METHODS:Single-center, retrospective...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-4935-5

    authors: Fernández-Blanco JI,Fernández-Díaz G,Cara C,Vera MI,Olivares D,Taxonera C

    更新日期:2018-03-01 00:00:00

  • Neuropeptides and nerve growth in inflammatory bowel diseases: a quantitative immunohistochemical study.

    abstract::Many studies have indicated changes in neuropeptides in inflammatory bowel disease (IBD), but with contradictory results. Nerve growth factor also has a potential role in the maintenance of enteric nerves and may be associated with IBD. A quantitative immunohistochemical method was used to measure area density of immu...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1017943430627

    authors: Lee CM,Kumar RK,Lubowski DZ,Burcher E

    更新日期:2002-03-01 00:00:00

  • Primary histiocytic lymphoma of the esophagus.

    abstract::Squamous cell carcinoma represents the most common primary malignant lesion of the esophagus (1). The initial manifestation of lymphosarcoma infrequently occurs in the gastrointestinal tract, and in one large series, there were no lymphosarcomas presenting in the esophagus (2). In the case described below, a primary h...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01324907

    authors: Berman MD,Falchuk KR,Trey C,Gramm HF

    更新日期:1979-11-01 00:00:00

  • Correction to: Crohn's Disease Only Visible on Small Bowel Capsule Endoscopy: A New Entity.

    abstract::The original version of the article unfortunately contained an error in the surname of the second author, Dr. Ferdinando D'Amico in the author group. ...

    journal_title:Digestive diseases and sciences

    pub_type: 已发布勘误

    doi:10.1007/s10620-020-06613-8

    authors: Chateau T,D'Amico F,Zallot C,Mathieu N,Peyrin-Biroulet L

    更新日期:2020-09-25 00:00:00

  • Prevention of Esophageal Strictures After Endoscopic Submucosal Dissection: A Promising Therapy Using Carboxymethyl Cellulose Sheets.

    abstract:BACKGROUND:Esophageal stricture is one of the serious adverse events following endoscopic submucosal dissection (ESD). However, optimum preventive techniques are still lacking. AIMS:Our primary objective was to evaluate the incidence of post-ESD esophageal stricture with the application of carboxymethyl cellulose (CMC...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-016-4034-4

    authors: Lua GW,Tang J,Liu F,Li ZS

    更新日期:2016-06-01 00:00:00

  • Changes of the intestinal microbiota, short chain fatty acids, and fecal pH in patients with colorectal cancer.

    abstract:BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-012-2526-4

    authors: Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

    更新日期:2013-06-01 00:00:00

  • Physiology and pharmacology of prostaglandins.

    abstract::Prostaglandins (PGs) are products of polyunsaturated acid metabolism, particularly arachidonic acid (AA) released from membrane phospholipids by the action of phospholipase A2 in response to a variety of physical, chemical, and neurohormonal factors. AA is rapidly metabolized to oxygenated products by two distinct enz...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/BF01309317

    authors: Konturek SJ,Pawlik W

    更新日期:1986-02-01 00:00:00

  • Role of food in appearance of growth-stimulating activity in rat proximal intestine after small-bowel resection.

    abstract::The oral intake of food is important for the observed compensatory hyperplasia in the remnant small intestine after resection but the molecular events governing this response are not known. Peptides, of molecular weight 4500 and 1000 daltons, present in the the proximal intestine for 96 hr after resection and mitogeni...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536635

    authors: Grey VL,Morin CL

    更新日期:1988-01-01 00:00:00

  • Effects of graded amounts of intragastric calcium on acid secretion, gastrin release, and gastric emptying in normal and duodenal ulcer subjects.

    abstract::We studied effects of graded concentrations of intragastric calcium on acid secretion, residual gastric volume, and serum gastrin and calcium levels. Intragastric titration was performed with solutions of isotonic mannitol or mannitol plus 2.5, 6, 16, 39, and 97 mM CaCl(2) in 10 normal and eight duodenal ulcer subject...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02430525

    authors: Barclay G,Maxwell V,Grossman MI,Solomon TE

    更新日期:1983-05-01 00:00:00

  • Failure of inhibitor assay to determine isoamylase distribution.

    abstract::Isoamylase distribution in the urine of normal individuals and patients admitted to the hospital with hyperamylasemia was determined by a wheat inhibitor mmethod and compared to results obtained by cellulose-acetate electrophoresis. We report two cases where the inhibitor ethod failed to give accurate results in urine...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01311727

    authors: Gersten M,Bank S,Lendvai S

    更新日期:1983-11-01 00:00:00

  • Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide.

    abstract::Several epidemiological studies have demonstrated a close association between Helicobacter pylori infection and carcinoma of the mid- or distal stomach. If this can be shown to be a causal association, eradication of the organism may prevent later development of cancer. Several mechanisms have been proposed by which H...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Hahm KB,Lee KJ,Kim JH,Cho SW,Chung MH

    更新日期:1998-09-01 00:00:00

  • Saccharomyces boulardii in maintenance treatment of Crohn's disease.

    abstract::The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1023/a:1005588911207

    authors: Guslandi M,Mezzi G,Sorghi M,Testoni PA

    更新日期:2000-07-01 00:00:00

  • A Prospective Study on Contrast-Enhanced Endoscopic Ultrasound for Differential Diagnosis of Pancreatic Cystic Neoplasms.

    abstract:BACKGROUND AND AIMS:To determine the value of contrast-enhanced endoscopic ultrasound (CE-EUS) for differentiation of pancreatic cystic neoplasms (PCNs). METHODS:From April 2015 to December 2017, 82 patients were enrolled in this study. All patients were confirmed to have PCNs by surgical pathology. Prior to surgery, ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-019-05718-z

    authors: Zhong L,Chai N,Linghu E,Li H,Yang J,Tang P

    更新日期:2019-12-01 00:00:00

  • Effectiveness of concomitant enteral nutrition therapy and infliximab for maintenance treatment of Crohn's disease in adults.

    abstract:BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-012-2374-2

    authors: Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

    更新日期:2013-05-01 00:00:00

  • Impact of gastrointestinal dysfunction on survival after liver transplantation for familial amyloidotic polyneuropathy.

    abstract::Liver transplantation is the only effective treatment of familial amyloidotic polyneuropathy type I (FAP). The aim of the present investigation was to identify factors at the time of submission for transplantation that had impact on survival, with special reference to gastrointestinal disturbances. All 28 liver-transp...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02093589

    authors: Suhr O,Danielsson A,Rydh A,Nyhlin N,Hietala SO,Steen L

    更新日期:1996-10-01 00:00:00

  • Graded esophageal balloon distention. A new provocative test for noncardiac chest pain.

    abstract::The evaluation of suspected esophageal chest pain is frustrating because of difficulty in clearly implicating the esophagus. Balloon distention was considered as a new provocative test in the esophagus because it has been shown to safely produce pain in other hollow gastrointestinal organs. Studies were performed in 5...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01299805

    authors: Barish CF,Castell DO,Richter JE

    更新日期:1986-12-01 00:00:00

  • Effects of metronidazole and misoprostol on indomethacin-induced changes in intestinal permeability.

    abstract::In previous open studies, misoprostol and metronidazole reduced nonsteroidal anti-inflammatory drug-induced intestinal permeability changes and inflammation respectively. We assessed the effects of indomethacin treatment (50 mg three times a day) for one week with either coadministered metronidazole (400 mg twice a da...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01316493

    authors: Davies GR,Wilkie ME,Rampton DS

    更新日期:1993-03-01 00:00:00

  • Validation of the 7th edition TNM staging system for hepatocellular carcinoma: an analysis of 8,828 patients in a single medical center.

    abstract:BACKGROUND:Major modification of the 7th tumor-node-metastasis (TNM) staging system for hepatocellular carcinoma (HCC) was divided into 6th stage IIIA to 7th IIIA (multiple tumors, any>5 cm) and IIIB (tumors involving a major vessel). This study aimed to validate 6th and 7th TNM systems in prognostic prediction, then a...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-013-2716-8

    authors: Kee KM,Wang JH,Lin CY,Wang CC,Cheng YF,Lu SN

    更新日期:2013-09-01 00:00:00

  • Measurement of serum electrolytes and phosphate after sodium phosphate colonoscopy bowel preparation: an evaluation.

    abstract::Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-2780-9

    authors: Ainley EJ,Winwood PJ,Begley JP

    更新日期:2005-07-01 00:00:00

  • Patients over Age 75 Are at Increased Risk of Emergency Department Visit and Hospitalization Following Colonoscopy.

    abstract:BACKGROUND:The age to stop screening or surveillance colonoscopy is not well established, and unplanned hospital use after colonoscopy in the elderly is not well understood. AIMS:To evaluate unplanned emergency department (ED) visits and hospitalization in patients over 75 within 7 days of outpatient colonoscopy. MET...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-019-05962-3

    authors: Grossberg LB,Papamichael K,Leffler DA,Sawhney MS,Feuerstein JD

    更新日期:2020-07-01 00:00:00

  • A De Novo mutation of STK11 gene in a Chinese patient with Peutz-Jeghers syndrome.

    abstract::Peutz-Jeghers syndrome (PJS) is an autosomal-dominant inherited disorder characterized by mucocutaneous pigmentation, hamartomatous polyposis of the gastrointestinal tract, and an increased risk for the development of both gastrointestinal and extraintestinal malignancies. Germline mutation of the STK11 gene, which en...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-009-0837-x

    authors: Gao Y,Zhang FM,Huang S,Wang X,Zhang P,Huang XD,Ji GZ,Fan ZN

    更新日期:2010-04-01 00:00:00