Abstract：
:The oral intake of food is important for the observed compensatory hyperplasia in the remnant small intestine after resection but the molecular events governing this response are not known. Peptides, of molecular weight 4500 and 1000 daltons, present in the the proximal intestine for 96 hr after resection and mitogenic for the intestine have been implicated in the adaptive hyperplasia. In this study, the role of food in the appearance of these peptides was assessed. The results show that after resection, rats nourished intravenously demonstrated neither a significant adaptation nor any of the detectable mucosal mitogens, whereas the rats nourished intragastrically demonstrated both hyperplasia and the mitogenic peptide(s). The association of the hyperplasia with the appearance of the mitogenic peptides in the small intestine suggests that they are important in the mechanism by which food promotes the adaptive hyperplasia.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Grey VL,Morin CLdoi
10.1007/BF01536635subject
Has Abstractpub_date
1988-01-01 00:00:00pages
78-82issue
1eissn
0163-2116issn
1573-2568journal_volume
33pub_type
杂志文章abstract：:The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/BF02208664
更新日期：1995-09-01 00:00:00
abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01303166
更新日期：1993-09-01 00:00:00
abstract：:Hepatic steatosis is a recognized feature of hepatitis C viral infection, particularly in genotype 3. The demographics and the associations contributing to moderate to severe steatosis in genotype 3 are not very well studied. The aim of this study is to determine the demographics and association of steatosis with fibr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/b:ddas.0000011597.92851.56
更新日期：2004-01-01 00:00:00
abstract：:Stimulation of the intrinsic nerves of the esophageal body leads to a twitch of the circular muscle after the end of the stimulation (the esophageal off-response), and the twitch spreads in the distal direction because of a latency gradient in the onset of the off-response between the proximal and the distal esophagus...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536324
更新日期：1989-04-01 00:00:00
abstract：:The diagnostic accuracy of two different methods of sectioning rectal biopsies was evaluated prospectively. The frequency of focal and diffuse findings in more than 80 serial sections from a limited portion of the well-oriented areas of 74 biopsies was compared with that found in three or more step sections distribute...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01295652
更新日期：1982-05-01 00:00:00
abstract：BACKGROUND:Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 μm. AIM:Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barrett's esophagus (BE),...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-013-2625-x
更新日期：2013-08-01 00:00:00
abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01538066
更新日期：1989-09-01 00:00:00
abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018828507990
更新日期：1997-08-01 00:00:00
abstract：:Insulinlike growth factor-1 (IGF-1) is an anabolic hormone synthesized by the liver upon stimulation by growth hormone (GH). IGF-1 exerts important effects on renal hemodynamics and renal sodium handling. The bioactivity of this hormone is influenced by its binding proteins (BP) of which IGF-BP3 favors retention in th...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1010631800505
更新日期：2001-06-01 00:00:00
abstract：:An important histologic feature of inflammatory bowel disease (IBD) is infiltration of the colonic mucosa with neutrophils. To investigate the nature of the chemotactic agents responsible for this infiltration, colonic mucosa from three normals and nine patients with inflammatory bowel disease (seven ulcerative coliti...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296664
更新日期：1987-12-01 00:00:00
abstract：:The significance of hyperplastic polyps of the gastric antrum in anemic patients with suspected gastrointestinal bleeding has not been determined. The aim of this study is to evaluate the prevalence and prognosis of such polyps in this patient group. Clinical records of patients referred to our endoscopy lab from Nove...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-9182-5
更新日期：2007-01-01 00:00:00
abstract：:A 36-year-old female with a six-year history of Crohn's disease of the anus and colon was found to have in situ cloacogenic carcinoma of the anus after having undergone total proctocolectomy for massive bleeding. This case further supports the association between Crohn's disease of the gastrointestinal tract and its p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01395512
更新日期：1980-06-01 00:00:00
abstract：:Octreotide is an effective therapeutic option in controlling secretory diarrhea of varied etiology. However, marked patient-to-patient differences in the antidiarrheal effects necessitate titration of octreotide dose in individual patients to achieve optimal symptom control. A consensus development panel established g...
journal_title：Digestive diseases and sciences
pub_type： 共识发展会议,杂志文章,评审
doi：10.1007/BF02285194
更新日期：1995-07-01 00:00:00
abstract：:Bone loss is an established complication of cholestatic liver cirrhosis, while little is known about bone mass and metabolism in noncholestatic liver cirrhosis. The aim of the present study is, therefore, to evaluate bone mass and mineral metabolism in patients with liver cirrhosis secondary to viral hepatitis. Bone m...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005568406664
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10620-012-2206-4
更新日期：2012-10-01 00:00:00
abstract：:Inadequate vegetable intake appears to increase colon cancer risk. Since genetic variation in taste influences vegetable preference, we tested associations between bitterness of 6-n-propylthiouracil (PROP), a measure of taste genetics, and number of colonic polyps, a measure of colon cancer risk, in 251 men who underw...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-2462-7
更新日期：2005-03-01 00:00:00
abstract：:Gastric stasis and duodenogastric reflux have each been implicated in the pathogenesis of various upper gastrointestinal disorders. However, the relationship between intragastric bile and gastric emptying has not been explored. In each of nine healthy volunteers (seven men and two women, ages 22-47 years), gastric emp...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01535751
更新日期：1988-03-01 00:00:00
abstract：:Changes in colonic motility were compared in dogs undergoing autonomic denervation of the paraaortic and presacral (group A), paraaortic (group B), or mesocolonic region (group C), and sham operation (group D). Five bipolar recording electrodes were placed into the seromuscular layer of the colon and rectum. The numbe...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018827613809
更新日期：1997-09-01 00:00:00
abstract：:Published clinical trials (N = 56) of antisecretory drugs in the treatment of benign gastric ulcer were reviewed. Composite healing rates for various drug regimens were calculated using a method previously described for duodenal ulcer. Healing rates were compared with data on suppression of intragastric acidity to see...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,评审
doi：10.1007/BF01798367
更新日期：1988-05-01 00:00:00
abstract：:The relationship between the GOT/GPT ratio in nonviral liver disorders and underlying physical condition and life-style were evaluated. The subjects were 12,808 male railway company workers who underwent an annual health checkup. Nonviral liver disorders were defined as elevated transaminases (GOT > 76 IU/liter or GPT...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1017959801493
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND AND AIMS:To determine the value of contrast-enhanced endoscopic ultrasound (CE-EUS) for differentiation of pancreatic cystic neoplasms (PCNs). METHODS:From April 2015 to December 2017, 82 patients were enrolled in this study. All patients were confirmed to have PCNs by surgical pathology. Prior to surgery, ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05718-z
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND AND AIMS:To study pre-operative and peri-operative course and outcome on follow up after pancreaticoduodenenctomy (PD) for resectable pancreatic cancer amongst patients receiving self-expanding metal stents (SEMS). METHODS:Medical charts of consecutively reviewed patients (2005-2009) with resectable pancrea...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1815-7
更新日期：2011-12-01 00:00:00
abstract：:Liver transplantation is the only effective treatment of familial amyloidotic polyneuropathy type I (FAP). The aim of the present investigation was to identify factors at the time of submission for transplantation that had impact on survival, with special reference to gastrointestinal disturbances. All 28 liver-transp...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02093589
更新日期：1996-10-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) is a common disease in infants and children. Prolonged (24-hr) pH monitoring in the esophagus for determination of increased acid exposure has, together with endoscopy, been the only routinely implemented method for GERD diagnosis. The recently introduced multiple intraluminal im...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-9731-y
更新日期：2007-09-01 00:00:00
abstract：:The intrarectal administration of trinitrobenzene sulfonic acid in rats induces ulcerative colitis, which results in histological alterations of colonic mucosa, severe modification of the cellular antioxidant defense system, and enhanced production of inflammatory eicosanoids. This study evaluated the influence of dif...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026655311878
更新日期：1998-12-01 00:00:00
abstract：:Concentration and voltage dependence of Mg transport across the rat duodenum was measured in an Ussing chamber. Mucosa (m) to serosa (s) Mg flux exhibits a cellular fraction comparable to that found for Ca. Mg sm flux is purely diffusive and probably restricted to the paracellular pathway. At all concentrations betwee...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296406
更新日期：1991-11-01 00:00:00
abstract：:The double pylorus is a fistulous communication between the gastric antrum and duodenal bulb. In most instances, it is believed to be a complication of peptic ulcer disease. In prior reports, the longest follow-up has been only 5 years. We report four cases of double pylorus, three of which have been followed medicall...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296254
更新日期：1984-03-01 00:00:00
abstract：:A case of heterotopic bone formation in a primary rectal adenocarcinoma was recently observed in a 54-year-old woman. This unusual finding was present both in the diagnostic biopsy and in the subsequently resected bowel. Pertinent gross and microscopic features are presented. This report represents the twelfth case in...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/BF01296512
更新日期：1992-10-01 00:00:00
abstract：BACKGROUND:Lymphocytic esophagitis is a rare esophageal condition. Our knowledge of potential risk factors and treatment outcomes of lymphocytic esophagitis is limited. AIM:To investigate potential risk factors associated with the development of lymphocytic esophagitis and compare clinical characteristics and treatmen...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06706-4
更新日期：2020-11-20 00:00:00
abstract：:Although gastric cancer formation with H. pylori in Mongolian gerbils was recently reported, the same inoculation procedure did not result in cancer formation in other animals such as mice. Disturbed regulation of apoptosis and cell proliferation are known to link the multistep process of carcinogenesis. The present s...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1013219621422
更新日期：2002-01-01 00:00:00
