Expression of gastric antisecretory and prostaglandin E receptor binding activity of misoprostol by misoprostol free acid.

abstract：:The protective effect of a human strain of Bifidobacterium bifidum (B. bifidum) against murine group A rotavirus (MRV) was examined in the intestines of BALB/c infected mice. In experiments designed to determine whether B. bifidum mediated MRV shedding during diarrheal disease, pregnant dams (and their expected litter...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Riepenhoff-Talty M,Dryja D,Sayahtaheri-Altaie S,Griffiths E,Ruffin D,Barrett H,Ogra PL

更新日期：1994-11-01 00:00:00

abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

journal_title：Digestive diseases and sciences

authors： Eaves ER,Hansky J

更新日期：1987-01-01 00:00:00

abstract：:Intravenous lidocaine was infused at 0.82 ml/min in a concentration of 1.2 mg/ml (2.3 mg/kg) for 120 min in awake chair-restrained baboons (Papio anubis), and measurements of esophageal peristalsis and LES pressure were compared before and after lidocaine or control infusions. Lidocaine produced a progressive and sign...

journal_title：Digestive diseases and sciences

authors： Sinar DR,Carey LC,Cordova C,Fletcher JR,Castell DO

更新日期：1985-11-01 00:00:00

abstract：:Although the pathogenic mechanisms of inflammatory bowel diseases are not fully understood, colonic microbiota may affect the induction of colonic inflammation, and some probiotics and prebiotics have been reported to suppress colitis. The inhibitory effects of brown rice fermented by Aspergillus oryzae (FBRA), a fibe...

journal_title：Digestive diseases and sciences

authors： Kataoka K,Ogasa S,Kuwahara T,Bando Y,Hagiwara M,Arimochi H,Nakanishi S,Iwasaki T,Ohnishi Y

更新日期：2008-06-01 00:00:00

abstract：:Changes in colonic motility were compared in dogs undergoing autonomic denervation of the paraaortic and presacral (group A), paraaortic (group B), or mesocolonic region (group C), and sham operation (group D). Five bipolar recording electrodes were placed into the seromuscular layer of the colon and rectum. The numbe...

journal_title：Digestive diseases and sciences

authors： Ishikawa M,Mibu R,Iwamoto T,Konomi H,Oohata Y,Tanaka M

更新日期：1997-09-01 00:00:00

abstract：:The effect of smoking on interdigestive gastrointestinal motility is little studied but may play a role in gastrointestinal morbidity. We studied gastroduodenal motility in 10 volunteers (five smokers and five nonsmokers) using a water-perfused pressure catheter. A pH probe was placed in the duodenal bulb. Baseline mo...

journal_title：Digestive diseases and sciences

authors： McDonnell WM,Owyang C

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis are at high readmission risk. Using a large statewide database, we evaluated the effect of hospital cirrhosis-related patient volume on 30-day readmissions in patients with cirrhosis. METHODS:We conducted a retrospective study of the Healthcare Cost and Utilization Project State Inpa...

journal_title：Digestive diseases and sciences

authors： Wei M,Ford J,Li Q,Jeong D,Kwong AJ,Nguyen MH,Chang MS

更新日期：2018-09-01 00:00:00

abstract：:Altered peripheral neutrophil function is a feature of IBD that may contribute to the chronicity and extragastrointestinal manifestations of this disease, but clinical evidence for such alterations is confounded by variations in patient characteristics, disease onset, and use of therapeutics that can influence neutrop...

journal_title：Digestive diseases and sciences

authors： Carter L,Wallace JL

更新日期：1995-01-01 00:00:00

abstract：:Following surgical operations, opiate analgesics are widely used to control pain. This situation was used to investigate patterns of human gastroduodenal motility and the effect of opiate analgesics on this motility during the early postoperative period. Gastric contractions were absent for 6--12 hr following surgery ...

journal_title：Digestive diseases and sciences

authors： Ingram DM,Catchpole BN

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:There are many studies on submucosal injection materials, but their clinical use is restricted for various reasons. The objective of this study was to compare the feasibility and safety of injected EndoClot®SIS polysaccharide as a submucosal injection material (SFC) in ESD in the pig stomach to that of injec...

journal_title：Digestive diseases and sciences

authors： Dai MS,Hu KW,Wu W,Yin GJ,Hu DM

更新日期：2019-10-01 00:00:00

abstract：:It has not been fully understood how intact protein antigens escape digestion in the course of absorption. The present study was designed to investigate the mechanism that heat stress induced an increase in intact protein antigen absorption. Human colonic cell line Caco-2 cells were treated with high temperature (37 t...

journal_title：Digestive diseases and sciences

authors： Yang PC,Wang CS

更新日期：2006-05-01 00:00:00

abstract：:We examined the role of capsaicin-sensitive afferent neurons in pH-dependent gastrin secretion in the rat stomach. The change in serum gastrin levels relative to changes in luminal pH (using omeprazole for luminal alkalization or 0.1 N HCl for luminal acidification) was studied after oral administration of 4% lidocain...

journal_title：Digestive diseases and sciences

authors： Nojima K,Sumii K,Sumii M,Okahara S,Haruma K,Yoshihara M,Kajiyama G

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) are often immunosuppressed, and those patients receiving anti-tumor necrosis factor α (TNF) therapy can have lower antibody responses to vaccines. Pertussis cases are at their highest levels in the post-vaccine era. There is little data regarding responses to th...

journal_title：Digestive diseases and sciences

authors： Caldera F,Saha S,Wald A,Garmoe CA,McCrone S,Megna B,Ley D,Reichelderfer M,Hayney MS

更新日期：2018-06-01 00:00:00

abstract：:Although transient increases in intracellular Ca2+ ([Ca2+]i) underlie a number of important physiological processes, sustained elevations in [Ca2+]i mediate damage to a number of tissues and cell types including gastric mucosal cells. Increases in [Ca2+]i can activate phospholipid hydrolysis via increases in phospholi...

journal_title：Digestive diseases and sciences

authors： Tepperman BL,Soper BD

更新日期：1999-03-01 00:00:00

abstract：:Lansoprazole, a proton pump inhibitor, exerts prominent antiulcer activity via both antisecretory and mucosal protective actions. Although the antisecretory action has been explained by inactivation of (H+, K+)-ATPase in parietal cells, the mode of mucosal protective action remains to be elucidated. In the present stu...

journal_title：Digestive diseases and sciences

authors： Inada I,Satoh H

更新日期：1996-04-01 00:00:00

abstract：:Ninety-one patients with idiopathic constipation had segmental colonic transit studied with radiopaque markers using a new simplified technique to determine frequency and type of colonic transit time (CTT) abnormalities and to determine the utility of this test in planning therapy. Colonic transit studies defined four...

journal_title：Digestive diseases and sciences

authors： Chaussade S,Khyari A,Roche H,Garret M,Gaudric M,Couturier D,Guerre J

更新日期：1989-08-01 00:00:00

abstract：:To evaluate the effect of halofuginone on trinitrobenzene sulfonic acid (TNBS)-induced colonic injury, rats were given halofuginone (40 microg/kg, intraperitoneally) or saline 1 h before the induction of colitis, and the injections were continued twice daily for 3 days until they were decapitated. High macroscopic and...

journal_title：Digestive diseases and sciences

authors： Karakoyun B,Yüksel M,Ercan F,Salva E,Işik I,Yeğen BC

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND/AIMS:There is a lack of studies describing the epidemiology of colorectal cancer (CRC) in patients aged 75 years and older (elderly). Current guidelines recommend against routine screening colonoscopies in this population. We sought to describe the epidemiology of CRC in the elderly, utilizing a large, popul...

journal_title：Digestive diseases and sciences

authors： Chouhan V,Mansoor E,Parasa S,Cooper GS

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Split dose bowel preparations (SDP) have superior outcomes for colonoscopy as compared to evening before regimens. However, the association of the actual volume of the SDP to colonoscopy outcome measures has not been well studied. AIMS:Compare adenoma detection rate (ADR), sessile serrated polyp detection r...

journal_title：Digestive diseases and sciences

authors： Siddiki H,Ravi S,Al-Qaisi MT,Fath AR,Ramirez F,Crowell MD,Pannala R,Faigel DO,Gurudu SR

更新日期：2018-09-01 00:00:00

abstract：:The effect of dopamine on human gastric and small intestinal interdigestive motility was investigated in 12 subjects. Intestinal motility was recorded by means of a four-lumen polyvinyl probe with four open tips located 15 cm apart, continuously perfused with distilled water. In each subject during the same study, aft...

journal_title：Digestive diseases and sciences

authors： Marzio L,Neri M,Di Giammarco AM,Cuccurullo F,Lanfranchi GA

更新日期：1986-04-01 00:00:00

abstract：:The study investigated the effect of either nocturnal acid suppression by the H2 antagonist nizatidine 300 mg at night or prolonged acid suppression by the proton- pump inhibitor omeprazole 20 mg in the morning, during four weeks, on intragastric pH profile, occurrence of bacterial growth in gastric fluid and biopsies...

journal_title：Digestive diseases and sciences

authors： Brummer RJ,Stockbrügger RW

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Colonoscopy is associated with multiple adverse outcomes. With an aging population undergoing colorectal cancer screening, few modalities exist to assess the patient risk prior to colonoscopy. Frailty, the age-related decline in reserve and function across multiple organ systems, predicts poor surgical outco...

journal_title：Digestive diseases and sciences

authors： Taleban S,Toosizadeh N,Junna S,Golden T,Ghazala S,Wadeea R,Tirambulo C,Mohler J

更新日期：2018-12-01 00:00:00

abstract：:Acetic acid-induced pan colitis in rats leads not only to colonic injury but also to a bystander ileal injury, characterized by decreased fluid and electrolyte absorption without associated histological injury or infiltration of inflammatory cells. To examine the nature of this decreased ileal fluid and electrolyte ab...

journal_title：Digestive diseases and sciences

authors： Cui N,Madsen KL,Friend DR,Stevenson BR,Fedorak RN

更新日期：1996-02-01 00:00:00

abstract：:Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is, therefore, an attractive candidate gene for irritable bowel syndrome. Previous studies investigating the 5-HTTLPR and Stin2 VNTR...

journal_title：Digestive diseases and sciences

authors： Kohen R,Jarrett ME,Cain KC,Jun SE,Navaja GP,Symonds S,Heitkemper MM

更新日期：2009-12-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Obesity, gastroesophageal reflux, and Barrett's esophagus have all been linked to esophageal adenocarcinoma. In addition, the decline in Helicobacter pylori (H. pylori) infection in affluent societies has also been suggested to be a major factor in the recent rise in the incidence of esophageal adenocarcinom...

journal_title：Digestive diseases and sciences

authors： Lee YY,Raj SM,Sharif SE,Salleh R,Ayub MC,Graham DY

更新日期：2011-05-01 00:00:00

abstract：:Anorexia nervosa is considered one type of eating disorder that may result in severe malnutrition. Patients with this disorder commonly complain of postprandial nausea, abdominal pain, and distension. We describe the radiologic and motility abnormalities associated with anorexia nervosa in a 21-year-old female. Barium...

journal_title：Digestive diseases and sciences

authors： Buchman AL,Ament ME,Weiner M,Kodner A,Mayer EA

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The receptor for formylated peptides, formyl peptide receptor 1 (FPR1), potently activates and serves as a chemoattractant receptor for neutrophils. AIM:Given the abundance of neutrophils in the inflamed colon, our aim was to determine if the FPR1 mediates colonic neutrophil migration, using the dextran sod...

journal_title：Digestive diseases and sciences

authors： Farooq SM,Stadnyk AW

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Birth characteristics, including weight and gestational age, may be associated with risk of Barrett's esophagus (BE), the only known precursor for esophageal adenocarcinoma; however, data are limited. AIMS:To examine associations between various birth characteristics and BE, and whether these associations a...

journal_title：Digestive diseases and sciences

authors： Shiota S,El-Serag HB,Thrift AP

更新日期：2016-04-01 00:00:00