Rates of Prevalent Colorectal Cancer Occurrence in Persons 75 Years of Age and Older: A Population-Based National Study.

abstract：:The effects of the water-soluble and delayed-release formulations of a nonsteroidal antiinflammatory drug, diclofenac, on the healing of gastroduodenal mucosal lesions were compared in a double-blind, double cross-over, placebo-controlled endoscopic study conducted in 14 healthy volunteers. Severe endoscopic lesions (...

journal_title：Digestive diseases and sciences

authors： Stadler P,Armstrong D,Margalith D,Saraga E,Stolte M,Lualdi P,Mautone G,Blum AL

更新日期：1991-05-01 00:00:00

abstract：:Nearly all chronic anal fissures occur in the posterior midline of the anal canal. However, some of them are in the anterior midline and are rarely double or in the lateral anal walls. The aim of this study was to determine if the clinical, manometric and endosonographic characteristics in patients with chronic anal f...

journal_title：Digestive diseases and sciences

authors： Pascual M,Parés D,Pera M,Courtier R,Gil MJ,Puig S,Serrano A,Andreu M,Grande L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The incidence of Clostridium difficile infection is increasing in the United States. The aim of our investigation is to compare short-term and long-term outcomes of patients admitted with an ulcerative colitis (UC) flare and co-existent C. difficile infection to those of non-infected patients. METHODS:A his...

journal_title：Digestive diseases and sciences

authors： Jodorkovsky D,Young Y,Abreu MT

更新日期：2010-02-01 00:00:00

abstract：:Survivin is known to be overexpressed in various human malignancies, including pancreatic cancer, and to cause resistance to radiation and chemotherapy, so the regulation of this molecule could be a new strategy for treating pancreatic cancer. In our study, a short interfering RNA (siRNA) plasmid expression vector aga...

journal_title：Digestive diseases and sciences

authors： Liu WS,Yan HJ,Qin RY,Tian R,Wang M,Jiang JX,Shen M,Shi CJ

更新日期：2009-01-01 00:00:00

abstract：:Effects of selective beta-adrenoceptor agonists on rectosigmoid motility during prolonged rectal distension were studied in 12 healthy volunteers in a double-blind, randomized fashion. Continuous distension was performed with a balloon in the proximal part of the rectum. Pressure was recorded by this balloon and by a ...

journal_title：Digestive diseases and sciences

authors： Lyrenäs E,Abrahamsson H,Dotevall G

更新日期：1985-06-01 00:00:00

abstract：:Other studies have shown that both morphological and functional adaptation occur in the ileal mucosa after total colectomy and may be mediated by humoral factors. To elucidate the participation of peptide YY (PYY) in intestinal adaptation after total proctocolectomy with ileal pouch-anal anastomosis (IPAA), changes in...

journal_title：Digestive diseases and sciences

authors： Imamura M,Nakajima H,Mikami Y,Yamauchi H

更新日期：1999-05-01 00:00:00

abstract：INTRODUCTION:Scant data exist about accidental occupational injuries in endoscopy suites. This work systematically analyzes injuries, identifies workplace hazards, and proposes hazard remediation to potentially reduce risks. METHODS:A retrospective study was performed on 14 previously unreported injuries among 120 end...

journal_title：Digestive diseases and sciences

authors： Cappell MS

更新日期：2011-02-01 00:00:00

abstract：:We have previously shown that methane on lactulose breath test (LBT) is highly associated with constipation in IBS and that methane gas itself slows small bowel transit in dogs. Previous studies suggest that serotonin may have a role in the control of transit in IBS. In this study, we aim to evaluate the role of serot...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Kong Y,Park S

更新日期：2004-01-01 00:00:00

abstract：:Liver from neonatal rats injected with LD50 E. coli endotoxin was studied by light and electron microscopy. By 2 hr, there was margination and migration of polymorphonuclear leukocytes. Single cell necrosis was seen after 8 hr. At 16 hr, there were numerous necrotic foci in the mid-zonal region of hepatic lobules, as ...

journal_title：Digestive diseases and sciences

authors： Young RS,Woods C,Towfighi J

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Heat shock protein 70-2 (HSP70-2) has a cytoprotective role in various conditions and also protects the gastric mucosa. Recently, polymorphism of HSP70-2 at position 1267 was suggested to be associated with carcinogenesis. We investigated the association of this polymorphism with the risk of gastric cancer i...

journal_title：Digestive diseases and sciences

authors： Shibata T,Arisawa T,Tahara T,Yoshioka D,Maruyama N,Fujita H,Kamiya Y,Nakamura M,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2009-01-01 00:00:00

abstract：:In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...

journal_title：Digestive diseases and sciences

authors： Phillips WT,Schwartz JG,McMahan CA

更新日期：1993-01-01 00:00:00

abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...

journal_title：Digestive diseases and sciences

authors： Iino S,Hino K,Kuroki T,Suzuki H,Yamamoto S

更新日期：1993-04-01 00:00:00

abstract：:Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...

journal_title：Digestive diseases and sciences

authors： Abel E,Ekman T,Warnhammar E,Hultborn R,Jennische E,Lange S

更新日期：2005-09-01 00:00:00

abstract：:The impact of depression (assessed by the Beck Depression Inventory) on quality of life and outcome was prospectively assessed in adult patients with cirrhosis. Patients with depression had significantly poorer perceived quality of life (P = 0.006), poorer adaptive coping (P = 0.001), and lower functional status, i.e....

journal_title：Digestive diseases and sciences

authors： Singh N,Gayowski T,Wagener MM,Marino IR

更新日期：1997-07-01 00:00:00

abstract：:Our objective was to determine whether there are dominating racial differences in patient preferences for surgery that may explain the disparities in proctocolectomy utilization between African Americans (AA) and whites. We used the time trade-off technique to measure health preferences for undergoing ileal pouch anal...

journal_title：Digestive diseases and sciences

authors： Nguyen GC,Tuskey A,Bayless TM,LaVeist TA,Brant SR

更新日期：2008-03-01 00:00:00

abstract：:Basal gastric acid output was analyzed prospectively in 110 patients with endoscopically documented duodenal ulcer disease to determine the frequency of gastric acid hypersecretion in patients with bleeding versus nonbleeding ulcers. Thirty-eight patients with stigmata of an actively or recently bleeding duodenal ulce...

journal_title：Digestive diseases and sciences

authors： Collen MJ,Kalloo AN,Sheridan MJ

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Sorafenib, a drug that inhibits Raf serine/threonine kinases mediating cell proliferation and receptor tyrosine kinases involved in angiogenesis, is approved for treatment of advanced hepatocellular carcinoma. AIMS:To explore the efficacy and safety of sorafenib for treating advanced HCC, and to identify cl...

journal_title：Digestive diseases and sciences

authors： Xie B,Wang DH,Spechler SJ

更新日期：2012-05-01 00:00:00

abstract：:Idiopathic chronic constipation is a frequent and disabling symptom, but its pathophysiological grounds are still poorly understood. In particular, there is little knowledge about the relationships between distal (anorectal area) and proximal (colonic area) motor abnormalities in this condition, especially concerning ...

journal_title：Digestive diseases and sciences

authors： Bassotti G,Chiarioni G,Vantini I,Betti C,Fusaro C,Pelli MA,Morelli A

更新日期：1994-07-01 00:00:00

abstract：:Epidemiologic data have shown that cholecystectomy is associated with a moderately increased risk of esophageal adenocarcinoma. The study objective was to evaluate the role of refluxed bile. A total of 696 patients with upper gastrointestinal symptoms were included in the study, of whom 55 had a history of cholecystec...

journal_title：Digestive diseases and sciences

authors： Fein M,Bueter M,Sailer M,Fuchs KH

更新日期：2008-05-01 00:00:00

abstract：:Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on...

journal_title：Digestive diseases and sciences

authors： Yang AM,Shih SC,Chu CH,Wang TE,Yang WS

更新日期：2010-03-01 00:00:00

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Adenosine deaminase acting on RNA 1 (ADAR1) is known to mediate deamination of adenosine-to-inosine through binding to double-stranded RNA, the phenomenon known as RNA editing. Currently, the function of ADAR1 in gastric cancer is unclear. AIMS:This study was aimed at investigating RNA editing-dependent and...

journal_title：Digestive diseases and sciences

authors： Cho CJ,Jung J,Jiang L,Lee EJ,Kim DS,Kim BS,Kim HS,Jung HY,Song HJ,Hwang SW,Park Y,Jung MK,Pack CG,Myung SJ,Chang S

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND AIM:The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD...

journal_title：Digestive diseases and sciences

authors： Zhang RN,Zheng RD,Mi YQ,Zhou D,Shen F,Chen GY,Zhu CY,Pan Q,Fan JG

更新日期：2016-08-01 00:00:00

abstract：:The effect of psyllium hydrophilic mucilloid (PHM) when used as a laxative and/or stool softener on serum cholesterol concentrations was examined in 176 ambulatory elderly participants attending a health screening program. The change in one-year serum cholesterol concentration in subjects using PHM was compared with t...

journal_title：Digestive diseases and sciences

authors： Stewart RB,Hale WE,Moore MT,May FE,Marks RG

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Ileocolic anastomosis is an essential step in the treatment to restore continuity of the gastrointestinal tract following ileocolic resection in patients with Crohn's disease (CD). However, the association between anastomotic type and surgical outcome is controversial. AIMS:The aim of this meta-analysis is ...

journal_title：Digestive diseases and sciences

authors： He X,Chen Z,Huang J,Lian L,Rouniyar S,Wu X,Lan P

更新日期：2014-07-01 00:00:00

abstract：:To investigate the pathophysiological basis of Courvoisier's law, the gallbladder size and pliability were measured in chronic calculous cholecystitis with (7 patients) or without (25 patients) common duct obstruction, in periampullary malignancy (6 patients), and in the normal state (3 patients). The duration and lev...

journal_title：Digestive diseases and sciences

authors： Chung RS

更新日期：1983-01-01 00:00:00

abstract：:Fasting antroduodenal motor activity was studied in 15 dyspeptic patients with chronic superficial antral gastritis and Helicobacter pylori infection (group A), 10 dyspeptic patients with chronic superficial antral gastritis without Helicobacter pylori infection (group B), and eight healthy control subjects (group C) ...

journal_title：Digestive diseases and sciences

authors： Testoni PA,Bagnolo F,Masci E,Colombo E,Tittobello A

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Estradiol-17β-D-glucuronide (E17G) induces cholestasis in vivo, endocytic internalization of the canalicular transporters multidrug resistance-associated protein 2 (Abcc2) and bile salt export pump (Abcb11) being a key pathomechanism. Cyclic AMP (cAMP) prevents cholestasis by targeting these transporters bac...

journal_title：Digestive diseases and sciences

authors： Zucchetti AE,Barosso IR,Boaglio AC,Luquita MG,Roma MG,Crocenzi FA,Sánchez Pozzi EJ

更新日期：2013-06-01 00:00:00

abstract：:The effects of Sulglycotide were evaluated in a pilot study of active H. pylori+ atrophic gastritis. Ten informed patients (mean age 51 +/- 13 years) entered a double-blind study. Five received Sulglycotide 400 mg three times a day for one year, the other 5, placebo. At 0, 30, 90, 270, and 360 days of treatment, patie...

journal_title：Digestive diseases and sciences

authors： Bazuro GE,Dezi A,Pallotta L,Masci P,Teodori L,Trinca ML,Koch M,Capurso L

更新日期：1996-01-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00