Hepatic damage in neonatal rat due to E. coli endotoxin.

abstract：:Fractional systemic bioavailability of orally administered drugs was found to be unexpectedly low in liver cirrhosis, even after surgical portal-systemic shunting. Fecal loss or intestinal first-pass elimination were assumed to explain the finding. In this paper we evaluated alternative pathophysiological interpretati...

journal_title：Digestive diseases and sciences

authors： Molino G,Avagnina P,Garrone C,Sansoè G,Degerfeld MM,Peretti P,Tinivella M,Bianco S

更新日期：2001-03-01 00:00:00

abstract：:Fibronectin (FN) is important for wound healing via cell proliferation, adhesion, differentiation, and matrix formation. Fetal types of FN mRNA, which include the region of EIIIA or EIIIB, are well expressed during embryonic development and wound healing. This study was done to investigate the mRNA expression of full-...

journal_title：Digestive diseases and sciences

authors： Tominaga K,Higuchi K,Watanabe T,Fujiwara Y,Kim S,Arakawa T,Iwao H,Kuroki T

更新日期：2001-02-01 00:00:00

abstract：:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

journal_title：Digestive diseases and sciences

authors： Guslandi M,Mezzi G,Sorghi M,Testoni PA

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Triglyceride-rich lipoproteins are important in dietary lipid absorption and subsequent energy distribution in the body. Their importance in the gut-lymph may have been overlooked in sepsis, the most common cause of critical illness, and in gut ischemia-reperfusion injury, a common feature of many critical i...

journal_title：Digestive diseases and sciences

authors： Hong J,Nachkebia S,Tun SM,Petzer A,Windsor JA,Hickey AJ,Phillips AR

更新日期：2018-12-01 00:00:00

abstract：:The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Since inflammation and fatty changes are associated with hepatitis C (HCV) infection, we have tested the role of HCV in the genesis of NASH. Five consecutive cases of classic NASH were tested by Abbott anti-c100-3 EIA and polymerase cha...

journal_title：Digestive diseases and sciences

authors： Rogers DW,Lee CH,Pound DC,Kumar S,Cummings OW,Lumeng L

更新日期：1992-11-01 00:00:00

abstract：:Mannitol (molecular weight 182), lactulose (342), and polyethylene glycol 400 (range 242-550) absorption was studied in 25 controls, 22 untreated celiacs, and 13 treated celiacs. Untreated celiacs absorbed less mannitol and more lactulose than controls. Absorption of higher as well as lower molecular-weight polyethyle...

journal_title：Digestive diseases and sciences

authors： Ukabam SO,Cooper BT

更新日期：1984-09-01 00:00:00

abstract：:Previous studies have shown that duodenal motility patterns differ in preterm and term infants, but antral motor activities were not compared. Using a validated, low-compliance, continuous-perfusion, neonatal manometric system, antral and duodenal motility was studied in 19 preterm and nine term infants. Antral motili...

journal_title：Digestive diseases and sciences

authors： Ittmann PI,Amarnath R,Berseth CL

更新日期：1992-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) as an indication to liver transplant (LT) started as palliative treatment, then moved to potentially curative anti-cancer therapy and more recently entered the era of competition with non-cancer indications, consequent to the need of the society to target equal distribution of the limite...

journal_title：Digestive diseases and sciences

authors： Sposito C,Cucchetti A,Mazzaferro V

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) screening is a priority for the Veteran's Health Administration (VHA). Optimizing fecal occult blood testing (FOBT) is integral to CRC screening in health care systems. AIMS:The purpose of this study was to characterize the utilization of CRC testing in a large integrated health care...

journal_title：Digestive diseases and sciences

authors： Long MD,Lance T,Robertson D,Kahwati L,Kinsinger L,Fisher DA

更新日期：2012-02-01 00:00:00

abstract：:The study investigated the effect of either nocturnal acid suppression by the H2 antagonist nizatidine 300 mg at night or prolonged acid suppression by the proton- pump inhibitor omeprazole 20 mg in the morning, during four weeks, on intragastric pH profile, occurrence of bacterial growth in gastric fluid and biopsies...

journal_title：Digestive diseases and sciences

authors： Brummer RJ,Stockbrügger RW

更新日期：1996-10-01 00:00:00

abstract：:A novel probe was developed from genomic DNA of Helicobacter pylori ATCC type strain 43629. It hybridized with all 73 H. pylori clinical isolates tested but not with any of 183 non-H. pylori DNAs in dot blot hybridization. Typing tests revealed 41 different HaeIII-digestion patterns from 57 H. pylori strains tested. B...

journal_title：Digestive diseases and sciences

authors： Jiang C,Li C,Ha T,Ferguson DA Jr,Chi DS,Laffan JJ,Thomas E

更新日期：1998-06-01 00:00:00

abstract：:Diseases of the ileocecal junction are mostly ulcerative. The aim of this study was to investigate the value of colonoscopy on the diagnosis of the causes of ileocecal ulcer. Clinical manifestations, diagnosis, and endoscopic and histopathologic features of 52 hospitalized cases of ileocecal ulcer were retrospectively...

journal_title：Digestive diseases and sciences

authors： Cai J,Li F,Zhou W,Luo HS

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:Negative association has been reported between presence of Helicobacter pylori and developing gastroesophageal reflux disease (GERD) and its complications. The aim of this study was to determine whether H. pylori (HP) can be protective against GERD in an African American (AA) population. METHODS:Fro...

journal_title：Digestive diseases and sciences

authors： Ashktorab H,Entezari O,Nouraie M,Dowlati E,Frederick W,Woods A,Lee E,Brim H,Smoot DT,Ghadyari F,Kamangar F,Razjouyan H

更新日期：2012-11-01 00:00:00

abstract：:A prospective study was performed in 17 patients with achalasia of the esophagus determining the manometric characteristics of the gastroesophageal sphincter, correlating it with histological analysis by biopsies taken during surgery at the distal narrowed segment of the esophagus, at the location of the sphincter. Th...

journal_title：Digestive diseases and sciences

authors： Csendes A,Smok G,Braghetto I,Ramirez C,Velasco N,Henriquez A

更新日期：1985-10-01 00:00:00

abstract：:Pheripheral edema was observed in five female patients after taking proton pump inhibitors omeprazole, lansoprazole, or pantoprazole for 7-15 days for peptic acid diseases in recommended standard doses. Edema disappeared two to three days after stopping therapy but reappeared in all five patients after being reexposed...

journal_title：Digestive diseases and sciences

authors： Brunner G,Athmann C,Boldt JH

更新日期：2001-05-01 00:00:00

abstract：:The use of total parenteral nutrition and enteral nutrition in inflammatory bowel disease has become commonplace. Except for well-documented improvements in nutritional parameters, the efficacy of these treatments for primary therapy or for complications remains largely unproven. ...

journal_title：Digestive diseases and sciences

authors： Whittaker JS

更新日期：1987-12-01 00:00:00

abstract：:To examine the effect of preoperative total parenteral nutrition (TPN) on patients with Crohn's disease undergoing bowel resection, an historical cohort was assembled of 103 patients resected between 1982 and 1984 by a single surgical team. Preoperative, perioperative, and postoperative variables were compared between...

journal_title：Digestive diseases and sciences

authors： Lashner BA,Evans AA,Hanauer SB

更新日期：1989-05-01 00:00:00

abstract：:Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

journal_title：Digestive diseases and sciences

authors： Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemoradiation reduces local recurrence in locally advanced rectal cancer, and adherence to national and societal recommendations remains unknown. OBJECTIVE:To determine variability in guideline adherence in rectal cancer treatment and investigate whether hospital volume correlated with variabil...

journal_title：Digestive diseases and sciences

authors： Midura EF,Jung AD,Daly MC,Hanseman DJ,Davis BR,Shah SA,Paquette IM

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Liver transplant recipients often perform liver biopsy (LB), specially in the context of potentially recurring diseases, such as hepatitis C infection. However, the LB has risks of complications, despite being the gold standard. Transient elastography (TE) is a noninvasive method comparable to the LB to ev...

journal_title：Digestive diseases and sciences

authors： Della-Guardia B,Evangelista AS,Felga GE,Marins LV,Salvalaggio PR,Almeida MD

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Gastroparesis is a heterogeneous disorder. Patient characteristics and treatment responsiveness may differ based on the extent of delay in gastric emptying. AIMS:Characterize gastroparesis patients based on the degree of delay in gastric emptying, and assess the relationship of patient demographics, symptom...

journal_title：Digestive diseases and sciences

authors： Navas CM,Wadas ED,Zbib NH,Crowell MD,Lacy BE

更新日期：2020-04-18 00:00:00

abstract：BACKGROUND:Anemia is a common systemic complication of inflammatory bowel disease (IBD) and is associated with worse disease outcomes, quality of life, and higher healthcare costs. AIMS:The purpose of this study was to determine how anemia severity impacts healthcare resource utilization and if treatment of anemia was...

journal_title：Digestive diseases and sciences

authors： Blaney H,Vu P,Mathew A,Snelling R,England J,Duong C,Hammonds K,Johnson C

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:Our previous study has shown that MYO5B is downregulated in gastric cancer. However, the mechanism by which the expression of MYO5B was inhibited remains unknown. METHODS:Inspection of the human MYO5B locus uncovered a large and dense CpG island within the 5' region of this gene. Methylation-specific PCR (M...

journal_title：Digestive diseases and sciences

authors： Dong W,Wang L,Shen R

更新日期：2013-07-01 00:00:00

abstract：:This study was undertaken to determine whether the synthetic prostaglandin E2 analog enprostil is able to inhibit basal and postprandial hypergastrinemia induced by omeprazole. We also studied the effect of omeprazole, enprostil, and the combination of both drugs on serum pepsinogen A and C levels. Eight normal subjec...

journal_title：Digestive diseases and sciences

authors： Meijer JL,Crobach LF,Jansen JB,Lamers CB

更新日期：1994-03-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00

abstract：:Isosmotic liquid peptone meals adjusted to pH 7, 3, and 1.5 were instilled on separate days into the stomachs of 8 duodenal ulcer patients and 7 healthy controls. Using a marker-dilution method, duodenal acid load (DAL) was measured as the amount of unbuffered hydrogen ions delivered to the duodenum per unit time. Gas...

journal_title：Digestive diseases and sciences

authors： Lam SK,Isenberg JI,Grossman MI,Lane WH,Hogan DL

更新日期：1982-07-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor highly expressed in the colon and playing an anti-inflammatory role through inhibition of the NF-kappaB pathway. Toll-like receptor 4 (TLR4) has been known to mediate LPS-induced cellular signaling through activation of NF-kappaB pa...

journal_title：Digestive diseases and sciences

authors： Eun CS,Han DS,Lee SH,Paik CH,Chung YW,Lee J,Hahm JS

更新日期：2006-04-01 00:00:00

abstract：:Congenital gastric outlet anomalies are rarely seen defects resulting from early embryologic development of foregut. We report a case of congenital pyloric outlet anomaly in a 60-year-old man with mild postprandial epigastric discomfort of approximately 3 months' duration. Endoscopic examination of the stomach showed ...

journal_title：Digestive diseases and sciences

authors： Uraz S,Aygün C,Konduk T,Celebi A,Sentürk O,Hülagü S

更新日期：2007-04-01 00:00:00

abstract：:There continues to be disagreement regarding the effects of ethanol on gastric emptying. This study was designed to assess different degrees of ethanol exposure on gastric emptying. Scintigraphic gastric emptying studies were performed in healthy adult cats and the half time (t1/2) of gastric emptying was obtained fro...

journal_title：Digestive diseases and sciences

authors： Willson CA,Bushnell D,Keshavarzian A

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

journal_title：Digestive diseases and sciences

authors： Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

更新日期：2013-06-01 00:00:00