Reversible pheripheral edema in female patients taking proton pump inhibitors for peptic acid diseases.

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:S-isomer (S) pantoprazole is known to be more effective and less dependent on cytochrome 2C19 than R-isomer (R)-pantoprazole. AIM:The purpose of this study was to compare the efficacy and safety of S-pantoprazole 20 mg versus pantoprazole 40 mg for treatment of reflux esophagitis. METHODS:This multi-center...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Bak YT,Rhee PL,Kim SG,Jung HY,Seol SY

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:It is unclear whether the quality of bowel preparation affects colonoscopic detection of non-polypoid colorectal neoplasms (NP-CRNs). AIM:To evaluate the impact of bowel-cleansing quality on detection of NP-CRNs. METHODS:We performed a retrospective analysis of asymptomatic screening colonoscopy cases afte...

journal_title：Digestive diseases and sciences

authors： Oh CH,Lee CK,Kim JW,Shim JJ,Jang JY

更新日期：2015-08-01 00:00:00

abstract：:Gastric stasis and duodenogastric reflux have each been implicated in the pathogenesis of various upper gastrointestinal disorders. However, the relationship between intragastric bile and gastric emptying has not been explored. In each of nine healthy volunteers (seven men and two women, ages 22-47 years), gastric emp...

journal_title：Digestive diseases and sciences

authors： Parr NJ,Baker PR,Grime JS,Mackie CR

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND/AIMS:There is a lack of studies describing the epidemiology of colorectal cancer (CRC) in patients aged 75 years and older (elderly). Current guidelines recommend against routine screening colonoscopies in this population. We sought to describe the epidemiology of CRC in the elderly, utilizing a large, popul...

journal_title：Digestive diseases and sciences

authors： Chouhan V,Mansoor E,Parasa S,Cooper GS

更新日期：2018-07-01 00:00:00

abstract：:The present study reports the results of intravenous cyclosporine in 32 patients with refractory and/or severe attacks of ulcerative colitis (UC). Twenty of 32 patients responded to intravenous cyclosporine; cyclosporine was clinically effective and improved colonic lesions. However, one colonic perforation and one po...

journal_title：Digestive diseases and sciences

authors： Carbonnel F,Boruchowicz A,Duclos B,Soulé JC,Lerebours E,Lémann M,Belaïche J,Colombel JF,Cosnes J,Gendre JP

更新日期：1996-12-01 00:00:00

abstract：:Musashi-1 (Msi-1), a mammalian neural RNA-binding protein, has been found to play important roles in the maintenance of stem cell states and differentiation in neural stem cells and mouse intestinal cells. We explored Msi-1 expression and its potential implications in the human stomach. Reverse transcription-PCR revea...

journal_title：Digestive diseases and sciences

authors： Murata H,Tsuji S,Tsujii M,Nakamura T,Fu HY,Eguchi H,Asahi K,Okano H,Kawano S,Hayashi N

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary complications (BCs) occur in up to 40% of living donor liver transplant (LDLT) recipients. The aim of this study was to evaluate the efficacy of endoscopic therapy in the management of LDLT-related BCs. METHODS:A retrospective study of 100 LDLT recipients at a single transplant center over ...

journal_title：Digestive diseases and sciences

authors： Elwir S,Thompson J,Amateau SK,Trikudanathan G,Attam R,Hassan M,Kandaswamy R,Pruett T,Lake J,Chinnakotla S,Freeman ML,Arain MA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The influence of direct-acting antivirals (DAAs) on chronic hepatitis C (CHC)-related hepatocellular carcinoma (HCC) remains controversial. We investigated the effect of eradicating CHC using DAAs on treatment outcomes in patients with CHC-related HCC treated with transarterial chemoembolization (TA...

journal_title：Digestive diseases and sciences

authors： Hyun HK,Cho EJ,Park SY,Hong YM,Kim SS,Kim HY,Heo NY,Park JG,Sinn DH,Kang W,Jeong SW,Song MJ,Park H,Lee D,Lee YS,Cho SB,An CS,Rhee HJ,Lee HW,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Lee JH,Yu SJ,Kim YJ,Yoo

更新日期：2020-08-28 00:00:00

abstract：:The impact of treatment on progression of fibrosis in autoimmune hepatitis (AIH) is unknown. We assessed the changes in liver fibrosis before and after treatment among these patients. Nineteen AIH patients who had paired liver biopsies were studied. Of these, seven had been treated with 6 months of cyclosporine A and ...

journal_title：Digestive diseases and sciences

authors： Mohamadnejad M,Malekzadeh R,Nasseri-Moghaddam S,Hagh-Azali S,Rakhshani N,Tavangar SM,Sedaghat M,Alimohamadi SM

更新日期：2005-03-01 00:00:00

abstract：:Patients with persistently normal ALT affected with HCV-related chronic hepatitis exist. The natural history of liver disease in these patients was demonstrated to be very slow and progression to cirrhosis likely absent. The case we report describes the occurrence of hepatocellular carcinoma (HCC) in a patient with pe...

journal_title：Digestive diseases and sciences

authors： Persico M,Palmentieri B,Coppola L,Di Giacomo Russo G,De Marino F,De Sio I,Torella R

更新日期：2002-11-01 00:00:00

abstract：:Sodium butyrate is a well-recognized differentiating agent inducing alkaline phosphatase activity, one of the epithelial differentiation markers. When IEC6 cells, a nontransformed, small intestinal epithelial cell line, were cultured with butyrate, this substrate induced alkaline phosphate activity in a time- and dose...

journal_title：Digestive diseases and sciences

authors： Fukushima K,Sasaki I,Hasegawa H,Takahashi K,Naito H,Funayama Y,Matsuno S

更新日期：1998-05-01 00:00:00

abstract：:We investigated whether S-adenosyl-L-methionine (SAMe) influences the inhibitory effect of ethanol on bile secretion and ethanol hepatotoxicity in the isolated perfused rat liver. SAMe (25 mg/kg intramuscularly three times a day) was administered for three days consecutively. Liver was then isolated and perfused with ...

journal_title：Digestive diseases and sciences

authors： Alvaro D,Gigliozzi A,Piat C,Carli L,Bini A,La Rosa T,Furfaro S,Capocaccia L

更新日期：1995-07-01 00:00:00

abstract：:Local or national policy, patients' preferences, safety and/or economic concerns, or reimbursement issues may dictate stopping drug in inflammatory bowel diseases (IBD) patients. Sustained deep remission is an important predictor of a better outcome after anti-tumor necrosis (TNF) factor therapy discontinuation, inclu...

journal_title：Digestive diseases and sciences

authors： Williet N,Paul S,Peyrin-Biroulet L,Roblin X

更新日期：2016-04-01 00:00:00

abstract：:The effects of Sulglycotide were evaluated in a pilot study of active H. pylori+ atrophic gastritis. Ten informed patients (mean age 51 +/- 13 years) entered a double-blind study. Five received Sulglycotide 400 mg three times a day for one year, the other 5, placebo. At 0, 30, 90, 270, and 360 days of treatment, patie...

journal_title：Digestive diseases and sciences

authors： Bazuro GE,Dezi A,Pallotta L,Masci P,Teodori L,Trinca ML,Koch M,Capurso L

更新日期：1996-01-01 00:00:00

abstract：:The effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion were evaluated in a pylorus-ligated rat model. Oral administration of salicylate (50 mg/kg), aspirin (50 mg/kg), and indomethacin (3.5 mg/kg) significantly increased ulcerogenesis over the basal value by six- to sevenfold, but ib...

journal_title：Digestive diseases and sciences

authors： Wagner KA,Nandi J,King RL,Levine RA

更新日期：1995-01-01 00:00:00

abstract：:Hepatic vein thrombosis (Budd-Chiari syndrome) is a rare complication of ulcerative colitis and has not previously been reported in association with Crohn's disease. We here report the first known case of Crohn's disease presenting as the Budd-Chiari syndrome. ...

journal_title：Digestive diseases and sciences

authors： Maccini DM,Berg JC,Bell GA

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Sorafenib is a proven first-line treatment recommended for hepatocellular carcinoma (HCC) patients with portal vein invasion (PVI). However, multiple treatment modalities are used in clinical practice as a first-line option. This study is a prospective, observational, multicenter, cohort study evalu...

journal_title：Digestive diseases and sciences

authors： Sinn DH,Lee HW,Paik YH,Kim DY,Kim YJ,Kim KM,Bae SH,Kim JH,Seo YS,Jang JY,Jang BK,Yim HJ,Kim HJ,Lee BS,Kim BH,Kim IH,Cho EY,Lee JI,Suh KS

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) follows a relapsing and remitting course incurring cumulative bowel damage over time. The question of whether or not the timing of the initiating biologic therapy affects long-term disease progression remains unanswered. Herein, we calculated rates of change in the Lémann index-which q...

journal_title：Digestive diseases and sciences

authors： Panchal H,Wagner M,Chatterji M,Taouli B,McBride R,Patterson JR,Ungaro R,Dubinsky M,Cho J,Sachar DB

更新日期：2019-11-01 00:00:00

abstract：:Endoscopic photodynamic therapy with hematoporphyrin derivative was used in the primary treatment of 54 patients with inoperable gastrointestinal neoplasms. Patients were divided into three groups including 24 with esophageal squamous cell carcinoma, 14 with adenocarcinoma of the stomach or lower third of the esophagu...

journal_title：Digestive diseases and sciences

authors： Patrice T,Foultier MT,Yactayo S,Adam F,Galmiche JP,Douet MC,Le Bodic L

更新日期：1990-05-01 00:00:00

abstract：:In cases of difficult biliary cannulation, transpancreatic sphincterotomy (TPS) can be an alternative approach of biliary access. However, its success and safety profile have not been studied in detail. A systematic review and meta-analysis were performed to study the overall cannulation success and adverse events of ...

journal_title：Digestive diseases and sciences

authors： Pécsi D,Farkas N,Hegyi P,Varjú P,Szakács Z,Fábián A,Varga G,Rakonczay Z Jr,Bálint ER,Erőss B,Czimmer J,Szepes Z,Vincze Á

更新日期：2019-09-01 00:00:00

abstract：:To test the role of immune reactivity in the pathogenesis of hepatitis C, serum soluble immune factors were measured in a cohort of 57 patients with chronic hepatitis C, and in 20 healthy subjects. Levels of interleukin-1 beta, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and interleu...

journal_title：Digestive diseases and sciences

authors： Quiroga JA,Martin J,Pardo M,Carreño V

更新日期：1994-11-01 00:00:00

abstract：:The effect of luminal 150 mmol saline, 0.05-0.2% (w/v) lysolecithin, and 5-20% (v/v) ethanol was studied on the mucosal morphology of the proximal small intestine in conscious guinea pigs as well as on the mucosal penetration and transfer to portal venous blood of luminal horseradish peroxidase (HRP). No ultrastructur...

journal_title：Digestive diseases and sciences

authors： Talbot RW,Foster JR,Hermon-Taylor J,Grant DA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The detailed risk factors such as bleeding pattern, comorbidities, and medication usage of patients with obscure gastrointestinal bleeding (OGIB) are largely unknown. We evaluated the risk factors related to ulcerative and vascular lesions of the small intestine diagnosed by capsule endoscopy or bal...

journal_title：Digestive diseases and sciences

authors： Okamoto J,Tominaga K,Sugimori S,Kato K,Minamino H,Ominami M,Fukunaga S,Nagami Y,Kamata N,Yamagami H,Tanigawa T,Shiba M,Watanabe T,Fujiwara Y,Arakawa T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The performance characteristics of colonic sensation and motility measurements are unclear. AIM:To compare left colon compliance, tone, and sensation in males and females and to evaluate inter and intra-individual coefficients of variation (COV) in these measurements. METHODS:Data were acquired using stand...

journal_title：Digestive diseases and sciences

authors： Odunsi ST,Camilleri M,Bharucha AE,Papathanasopoulos A,Busciglio I,Burton D,Zinsmeister AR

更新日期：2010-03-01 00:00:00

abstract：:Cirrhotic patients with hepatocellular carcinoma (HCC) frequently develop hepatic encephalopathy. Metabolic etiology of encephalopathy is less often considered in these patients. Although paraneoplastic hypercalcemia may be associated with several malignant tumors, it has also been described in HCC [1-4], and may caus...

journal_title：Digestive diseases and sciences

authors： Tudela P,Soldevila B,Mòdol JM,Domènech E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Intestinal Behcet's disease (BD) is a specific subtype of BD. Effective drug therapy for intestinal BD remains elusive. AIMS:To investigate long-term outcomes and identify predictors of sustained response in intestinal BD patients receiving infliximab (IFX) treatment. METHODS:The medical records were revie...

journal_title：Digestive diseases and sciences

authors： Zou J,Ji DN,Cai JF,Guan JL,Bao ZJ

更新日期：2017-02-01 00:00:00

abstract：:Barrett's esophagus (BE) is intestinal metaplasia of the lower esophagus and a precursor lesion for esophageal adenocarcinoma (EAC). Both are important health issues as they have rising incidences in the Western world. Improving the management of BE relies on understanding the underlying biology of this disease, but t...

journal_title：Digestive diseases and sciences

authors： To H,Clemons NJ,Duong CP,Trainer AH,Phillips WA

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The purpose of this prospective study was to demonstrate the ability to measure pancreatic tumor tissue blood flow (TBF) with a noninvasive method using xenon inhalation computed tomography (xenon-CT) and to correlate TBF with histological features, particularly microvascular density (MVD). METHODS...

journal_title：Digestive diseases and sciences

authors： Kubota M,Murakami T,Nagano H,Eguchi H,Marubashi S,Kobayashi S,Wada H,Tanemura M,Dono K,Nakamori S,Sakon M,Monden M,Mori M,Doki Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Small bowel mass lesions (SBML) are a relatively common cause of obscure gastrointestinal bleeding (OGIB). Their detection has been limited by the inability to endoscopically examine the entire small intestine. This has changed with the introduction of capsule endoscopy (CE) and double balloon enteroscopy (D...

journal_title：Digestive diseases and sciences

authors： Ross A,Mehdizadeh S,Tokar J,Leighton JA,Kamal A,Chen A,Schembre D,Chen G,Binmoeller K,Kozarek R,Waxman I,Dye C,Gerson L,Harrison ME,Haluszka O,Lo S,Semrad C

更新日期：2008-08-01 00:00:00