The Genetics of Barrett's Esophagus: A Familial and Population-Based Perspective.

abstract：BACKGROUND:Ectopic expression of gastric intrinsic factor (IF) has been described in rodent models of chronic gastritis. AIMS:The current study undertook to determine if ectopic IF was also present in chronic gastritis in humans and might identify the process of ectopic protein expression as part of the response to ch...

journal_title：Digestive diseases and sciences

authors： Shao JS,Carmel R,Alpers DH

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between insulin resistance and post-ERCP pancreatitis (PEP) is not known. We aimed to determine the relation between pre-ERCP insulin resistance and risk of PEP, and to evaluate the relationship of insulin resistance with well-established risk factors for PEP. METHODS:Consecutive p...

journal_title：Digestive diseases and sciences

authors： Koksal AR,Boga S,Alkim H,Bayram M,Ergun M,Alkim C

更新日期：2016-08-01 00:00:00

abstract：:This study evaluated the gastroprotective activity of DA-6034 against various ulcerogens including ethanol, aspirin, indomethacin, stress, and acetic acid. The basic mechanisms of DA-6034 as a defensive factor such as mucus secretion and endogenous prostaglandin E(2) synthesis were determined. Rats with gastric lesion...

journal_title：Digestive diseases and sciences

authors： Choi SM,Shin JH,Kang KK,Ahn BO,Yoo M

更新日期：2007-11-01 00:00:00

abstract：:The interaction of [35S]methionine with hepatic tRNA in normal, carcinogen-treated, and partially hepatectomized rats was studied. tRNA was preferentially labeled following [35S]methionine (1.6 mCi, 25 mg/kg body wt) administration by intraperitoneal injection. The extent of [35S]methionine-tRNA interaction was impair...

journal_title：Digestive diseases and sciences

authors： Kanduc D,Quagliariello E

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Although the overall incidence of hepatitis B virus (HBV) has declined since the introduction of universal vaccine guidelines, the incidence remains elevated in high risk groups. Recent guidelines from the Centers for Disease Control (CDC) have underscored the importance of vaccination against HBV in high ri...

journal_title：Digestive diseases and sciences

authors： Foster T,Hon H,Kanwal F,Han S,Spiegel B

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Although a genetic component has been identified as a risk factor for developing inflammatory bowel disease, there is evidence that dietary factors also play a role in the development of this disease. AIMS:The aim of this study was to determine the effects of feeding a red meat diet with and without resista...

journal_title：Digestive diseases and sciences

authors： Le Leu RK,Young GP,Hu Y,Winter J,Conlon MA

更新日期：2013-12-01 00:00:00

abstract：:Hepatic vein thrombosis (Budd-Chiari syndrome) is a rare complication of ulcerative colitis and has not previously been reported in association with Crohn's disease. We here report the first known case of Crohn's disease presenting as the Budd-Chiari syndrome. ...

journal_title：Digestive diseases and sciences

authors： Maccini DM,Berg JC,Bell GA

更新日期：1989-12-01 00:00:00

abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...

journal_title：Digestive diseases and sciences

authors： Shimouchi A,Nose K,Takaoka M,Hayashi H,Kondo T

更新日期：2009-08-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：:This study was undertaken to determine whether the synthetic prostaglandin E2 analog enprostil is able to inhibit basal and postprandial hypergastrinemia induced by omeprazole. We also studied the effect of omeprazole, enprostil, and the combination of both drugs on serum pepsinogen A and C levels. Eight normal subjec...

journal_title：Digestive diseases and sciences

authors： Meijer JL,Crobach LF,Jansen JB,Lamers CB

更新日期：1994-03-01 00:00:00

abstract：:A classification of gastrointestinal motility disorders is offered based upon the type of disorder in transit (delay or acceleration), and the region of the gastrointestinal tract affected. Specific abnormalities of myoelectrical patterns are identified when possible and related to disturbances in transit in the stoma...

journal_title：Digestive diseases and sciences

authors： Vantrappen G,Janssens J,Coremans G,Jian R

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:Lifestyle and demographic risk factors for the development of oesophageal adenocarcinoma developing from columnar-lined oesophagus are not well defined. METHODS:Demographic and lifestyle factors, endoscopy and histology reports were extracted from 1,761 subjects from seven UK centres. The associations of co...

journal_title：Digestive diseases and sciences

authors： Gatenby PA,Caygill CP,Ramus JR,Charlett A,Watson A

更新日期：2008-05-01 00:00:00

abstract：:Wilson disease, an autosomal recessive disorder due to mutations of the ATP7B gene, is characterized by copper accumulation and toxicity in the liver and subsequently in other organs, mainly the brain and cornea. A new missense mutation (T1288R) of the ATP7B gene has recently been discovered in a Wilson disease patien...

journal_title：Digestive diseases and sciences

authors： Leggio L,Malandrino N,Loudianos G,Abenavoli L,Lepori MB,Capristo E,De Virgiliis S,Gasbarrini G,Addolorato G

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:We previously reported that preoperative chemolipiodolization of the whole liver is effective for reducing the incidence of postoperative recurrence and prolonging survival in patients with resectable hepatocellular carcinoma (HCC). The present randomized controlled trial was performed to evaluate the influe...

journal_title：Digestive diseases and sciences

authors： Kaibori M,Tanigawa N,Kariya S,Ikeda H,Nakahashi Y,Hirohara J,Koreeda C,Seki T,Sawada S,Okazaki K,Kwon AH

更新日期：2012-05-01 00:00:00

abstract：:Five cases of granular cell tumor of the esophagus are reported. In four cases, the tumor was an asymptomatic, incidental finding. In one case, a larger granular cell tumor presented with dysphagia and required local surgical excision. Long-term follow-up in three cases revealed no evidence of tumor progression. Esoph...

journal_title：Digestive diseases and sciences

authors： Brady PG,Nord HJ,Connar RG

更新日期：1988-10-01 00:00:00

abstract：:Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary bile acids were separated by chromatography, the majority ...

journal_title：Digestive diseases and sciences

authors： Raedsch R,Lauterburg BH,Hofmann AF

更新日期：1981-05-01 00:00:00

abstract：:MR enteroclysis is becoming a very important imaging modality in the workup and follow-up of small bowel diseases. The technique has many advantages, including the absence of ionizing radiation, ability to control luminal distension, superior tissue characterization, multiplanar capabilities, and mural and extramural ...

journal_title：Digestive diseases and sciences

authors： Wiarda BM,Kuipers EJ,Houdijk LP,Tuynman HA

更新日期：2005-06-01 00:00:00

abstract：:The gastroprotective agent ecabet sodium (ecabet, 12-sulfodehydroabietic acid monosodium salt) increases the formation of prostaglandin (PG) E2 and I2 by gastric mucosa. In the present study, we examined the effect of ecabet on metabolism of arachidonic acid (AA) in rat gastric mucosal cells. Ecabet (0.1-10 mM) concen...

journal_title：Digestive diseases and sciences

authors： Kinoshita M,Tamaki H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:IL-1β is a cytokine involved in mediating epithelial barrier dysfunction in the gut. It is known that IL-1β mediates activation of non-muscle myosin light chain kinase in epithelial cells, but the precise mechanism by which epithelial barrier dysfunction is induced by IL-1β is not understood. METHODS AND RE...

journal_title：Digestive diseases and sciences

authors： Haines RJ,Beard RS Jr,Chen L,Eitnier RA,Wu MH

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Immune balances are important for many diseases including ulcerative colitis (UC). This study aimed to explore the role of the balance between CD8+ CD28+ and CD8+ CD28- T lymphocytes for the immunological pathogenesis of UC. METHODS:Sixteen patients with UC, 16 patients with irritable bowel syndrome (IBS) a...

journal_title：Digestive diseases and sciences

authors： Dai SX,Wu G,Zou Y,Feng YL,Liu HB,Feng JS,Chi HG,Lv RX,Zheng XB

更新日期：2013-01-01 00:00:00

abstract：:Idiopathic chronic constipation is a frequent and disabling symptom, but its pathophysiological grounds are still poorly understood. In particular, there is little knowledge about the relationships between distal (anorectal area) and proximal (colonic area) motor abnormalities in this condition, especially concerning ...

journal_title：Digestive diseases and sciences

authors： Bassotti G,Chiarioni G,Vantini I,Betti C,Fusaro C,Pelli MA,Morelli A

更新日期：1994-07-01 00:00:00

abstract：:Ischemic enterocolitis is a well-recognized entity occurring in cocaine users. Diagnosis is based on the presence of rectal bleeding, abdominal pain, a history of cocaine use, supportive endoscopic and histopathologic findings, and the absence of other etiologic mechanisms of ischemic colitis. In this study, we evalua...

journal_title：Digestive diseases and sciences

authors： Niazi M,Kondru A,Levy J,Bloom AA

更新日期：1997-07-01 00:00:00

abstract：:Campylobacter pyloridis has been associated with antral gastritis and duodenal ulcer. To study the pathogenetic role of these organisms in duodenal ulcer, endoscopic biopsies, two from the first part of duodenum, four from antrum, and four from body and fundus, were taken before and after four weeks of cimetidine trea...

journal_title：Digestive diseases and sciences

authors： Hui WM,Lam SK,Chau PY,Ho J,Lui I,Lai CL,Lok AS,Ng MM

更新日期：1987-11-01 00:00:00

abstract：:An important histologic feature of inflammatory bowel disease (IBD) is infiltration of the colonic mucosa with neutrophils. To investigate the nature of the chemotactic agents responsible for this infiltration, colonic mucosa from three normals and nine patients with inflammatory bowel disease (seven ulcerative coliti...

journal_title：Digestive diseases and sciences

authors： Lobos EA,Sharon P,Stenson WF

更新日期：1987-12-01 00:00:00

abstract：:Previous studies have found a widely variable prevalence of dysplasia and cancer in colonic strictures in patients with ulcerative colitis. Consequently, therapeutic recommendations are conflicting. To better assess the prevalence, we reviewed the clinical and pathological findings in all 27 patients with ulcerative c...

journal_title：Digestive diseases and sciences

authors： Lashner BA,Turner BC,Bostwick DG,Frank PH,Hanauer SB

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:No study has evaluated current scoring systems for their accuracy in predicting short and long-term outcome of alcoholic hepatitis in a US population. METHODS:We reviewed electronic records for patients with alcoholic liver disease (ALD) admitted to Parkland Memorial Hospital between January 2002 and August...

journal_title：Digestive diseases and sciences

authors： Cuthbert JA,Arslanlar S,Yepuri J,Montrose M,Ahn CW,Shah JP

更新日期：2014-07-01 00:00:00

abstract：:Although various types of artificial liver support systems (ALSSs) including a hybrid type have been made, few are practical ALSSs for treatment of acute and/or chronic hepatic failure. Titanium oxide (TiO(2)), a stable material, dismantles various materials using a photocatalytic action under ultraviolet irradiation....

journal_title：Digestive diseases and sciences

authors： Shinohara H,Shimada M,Ikemoto T,Morine Y,Imura S,Fujii M,Imaizumi T,Murayama M,Aiba Y

更新日期：2007-09-01 00:00:00

abstract：:The hepatic stimulatory substance (HSS) extracted from weanling rat livers was purified 381,000-fold using chromatographic techniques including nondissociating polyacrylamide gel electrophoresis (nondenaturing PAGE). The activity of this highly purified HSS, named Acr-F4, was assessed in two in vivo models. In 40% hep...

journal_title：Digestive diseases and sciences

authors： Francavilla A,Barone M,Van Thiel DH,Mazzaferro V,Prelich JG,Starzl TE

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Although the use of cold snare polypectomy (CSP) has spread rapidly, its safety for pedunculated (Ip) polyps remains controversial. In particular, the outcomes of hot snare polypectomy (HSP) and CSP for Ip polyps have not been previously compared. AIMS:This study evaluated whether the rate of delayed postpo...

journal_title：Digestive diseases and sciences

authors： Arimoto J,Chiba H,Ashikari K,Fukui R,Tachikawa J,Okada N,Suto T,Kawano N,Niikura T,Kuwabara H,Nakaoka M,Ida T,Goto T,Nakajima A

更新日期：2020-07-04 00:00:00

abstract：:We studied the natural history of ulcerative colitis (UC) by following 1116 patients in whom UC had been diagnosed or confirmed at The Cleveland Clinic Foundation between 1960 and 1983. Data before 1973 were obtained retrospectively. Criteria for inclusion in the study were: a diagnosis of UC confirmed by clinical, ra...

journal_title：Digestive diseases and sciences

authors： Farmer RG,Easley KA,Rankin GB

更新日期：1993-06-01 00:00:00