Serum levels of soluble immune factors and pathogenesis of chronic hepatitis C, and their relation to therapeutic response to interferon-alpha.

abstract：BACKGROUND AND AIM:Self-expandable metal stents (SEMSs) have been a good treatment option for malignant intestinal obstruction. However, stent placement with a gastroscope can be technically difficult for the distal duodenum obstruction. A side-viewing duodenoscope may be helpful for these patients. We report our exper...

journal_title：Digestive diseases and sciences

authors： Park JM,Min BH,Lee SH,Chung KH,Lee JM,Song BJ,Lee JK,Ryu JK,Kim YT

更新日期：2015-02-01 00:00:00

abstract：:The purpose of the present study was to investigate the prognostic role of severe hypoxemia on admission as an independent risk factor of pulmonary complications and mortality in patients with acute pancreatitis. Pulmonary complications were studied in 166 previously healthy patients with acute pancreatitis. Forty-eig...

journal_title：Digestive diseases and sciences

authors： Polyzogopoulou E,Bikas C,Danikas D,Koutras A,Kalfarentzos F,Gogos CA

更新日期：2004-01-01 00:00:00

abstract：:Although transient increases in intracellular Ca2+ ([Ca2+]i) underlie a number of important physiological processes, sustained elevations in [Ca2+]i mediate damage to a number of tissues and cell types including gastric mucosal cells. Increases in [Ca2+]i can activate phospholipid hydrolysis via increases in phospholi...

journal_title：Digestive diseases and sciences

authors： Tepperman BL,Soper BD

更新日期：1999-03-01 00:00:00

abstract：:The involvement of oxygen free radicals in the development of the ethanol-induced gastric mucosal damage has been investigated. We found that oral administration of superoxide dismutase reduced the incidence of ethanol-induced mucosal lesions. Reduction of superoxide dismutase activity by diethyldithiocarbamate led to...

journal_title：Digestive diseases and sciences

authors： Szelenyi I,Brune K

更新日期：1988-07-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by peroral load of sucrose...

journal_title：Digestive diseases and sciences

authors： Borch K,Sjöstedt C,Hannestad U,Söderholm JD,Franzén L,Mårdh S

更新日期：1998-04-01 00:00:00

abstract：:The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All ...

journal_title：Digestive diseases and sciences

authors： Petroni ML,Jazrawi RP,Grundy A,Lanzini A,Pigozzi MG,Biasio A,Heaton KW,Virjee J,Northfield TC

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) appear to have increased intestinal permeability; it has been suggested that activation of protease-activated receptor-2 (PAR-2) receptors is responsible for this alteration. The aims of this study are to evaluate (1) if rectal (lar...

journal_title：Digestive diseases and sciences

authors： Lee JW,Park JH,Park DI,Park JH,Kim HJ,Cho YK,Sohn CI,Jeon WK,Kim BI

更新日期：2010-10-01 00:00:00

abstract：:Dysmotility and delayed emptying of the stomach have been reported in patients with chronic renal failure (CRF). The aim of this study was to investigate whether gastric myoelectrical activity was impaired in patients with CRF using electrogastrography. The electrogastrogram (EGG) was recorded in 24 symptomatic patien...

journal_title：Digestive diseases and sciences

authors： Lin X,Mellow MH,Southmayd L 3rd,Pan J,Chen JD

更新日期：1997-05-01 00:00:00

abstract：:The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial he...

journal_title：Digestive diseases and sciences

authors： Assy N,Hussein O,Khalil A,Luder A,Szvalb S,Paizi M,Spira G

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：:Some patients referred for esophagogastroduodenoscopy (EGD) to evaluate symptoms of dysphagia have normal endoscopies. How best to manage these patients is unclear. We reviewed our experience with empiric esophageal dilation in this setting. Over a five-year period, 40 consecutive patients with esophageal dysphagia an...

journal_title：Digestive diseases and sciences

authors： Marshall JB,Chowdhury TA

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Probe-based confocal laser endomicroscopy (pCLE) has enabled in vivo histopathology by obtaining high resolution images of the mucosal layers of the gastrointestinal tract. For indeterminate bile duct strictures, biopsy, cytologic brushing and needle aspiration have low levels of diagnostic accuracy. AIM:Th...

journal_title：Digestive diseases and sciences

authors： Talreja JP,Sethi A,Jamidar PA,Singh SK,Kwon RS,Siddiqui UD,Sawhney M,Bakhru MR,Gaidhane M,Kline P,Sauer BG,Kahaleh M

更新日期：2012-12-01 00:00:00

abstract：:Opioids, both endogenous and exogenous, have been shown to exert a modulating influence on many gastrointestinal functions. Animal studies suggest an inhibitory role for opioids in the control of pancreatic secretion, which may be exerted through their inhibitory effect on acetylcholine release from intramural neurons...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Saad C,Valenzuela JE

更新日期：1988-05-01 00:00:00

abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...

journal_title：Digestive diseases and sciences

authors： Sandler RS,Johnson MD,Holland KL

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Hepatoportal sclerosis (HPS) is a clinicopathologic condition that is clinically characterized by portal hypertension (varices and portosystemic collateral vessels), splenomegaly and pancytopenia, in the absence of cirrhosis. Although the etiology is obscure, a number of theories such as immunologic...

journal_title：Digestive diseases and sciences

authors： Beyazit Y,Ibis M,Purnak T,Turhan T,Kekilli M,Kurt M,Sayilir A,Onal IK,Turhan N,Tas A,Köklü S,Haznedaroglu IC

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Wnt ligand binding initiates the interaction between Frizzled and Dvl proteins. However, the regulation of Frizzled-Dvl proteins interaction remains largely unknown. AIMS:The present study aims to elucidate the regulation of Frizzled-Dvl interaction by WDR34. METHODS:The protein levels of WDR34 in hepatoce...

journal_title：Digestive diseases and sciences

authors： Luo X,Liu Y,Ma S,Liu L,Xie R,Wang S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Transmembrane and ubiquitin-like domain-containing 1 protein (Tmub1) negatively regulates liver regeneration. However, whether this regulation involves posttranscriptional modification of Tmub1 expression is unknown. AIM:The aim of the study was to investigate whether microRNA (miR)-27a/b regulates posttran...

journal_title：Digestive diseases and sciences

authors： Lan X,Li G,Liu H,Fu H,Chen P,Liu M

更新日期：2018-09-01 00:00:00

abstract：:Over the past two decades, evidence has accumulated to challenge the traditional view that cardiac mucosa, which is comprised exclusively of mucus glands, is the normal lining of the most proximal portion of the stomach (the gastric cardia). There is now considerable evidence to suggest that cardiac mucosa develops as...

journal_title：Digestive diseases and sciences

authors： Spechler SJ

更新日期：2018-08-01 00:00:00

abstract：:Patients with persistently normal ALT affected with HCV-related chronic hepatitis exist. The natural history of liver disease in these patients was demonstrated to be very slow and progression to cirrhosis likely absent. The case we report describes the occurrence of hepatocellular carcinoma (HCC) in a patient with pe...

journal_title：Digestive diseases and sciences

authors： Persico M,Palmentieri B,Coppola L,Di Giacomo Russo G,De Marino F,De Sio I,Torella R

更新日期：2002-11-01 00:00:00

abstract：:The objective of this study was to determine if HCV can be transmitted from patient to patient in psychiatric institutions and to determine possible routes of infection. We did a cross-sectional survey of 196 Japanese psychiatric patients tested for HCV and HBV markers and 400 age- and sex-matched controls. Anti-HCV w...

journal_title：Digestive diseases and sciences

authors： Sawayama Y,Hayashi J,Kakuda K,Furusyo N,Ariyama I,Kawakami Y,Kinukawa N,Kashiwagi S

更新日期：2000-02-01 00:00:00

abstract：:Pancreatic-type isoamylase (P-type) and salivary-type isoamylase (S-type) activities were determined by the wheat protein inhibitor method in 29 patients with end-stage renal disease and in 38 healthy volunteers. Serum levels of total amylase (322 +/- 43 units/liter) and P-type (212 +/- 39 units/liter) in ESRD were si...

journal_title：Digestive diseases and sciences

authors： Araki T,Ueda M,Taketa K,Kosaka K

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis is among the causes of refractory reflux disease. Biopsy of esophagus is the gold standard for diagnosis. In this study we determined the frequency of eosinophilic esophagitis (EE) in refractory reflux cases referred to Motility Department of Shahid Beheshti Research Center of Gastro...

journal_title：Digestive diseases and sciences

authors： Foroutan M,Norouzi A,Molaei M,Mirbagheri SA,Irvani S,Sadeghi A,Derakhshan F,Tavassoli S,Besharat S,Zali M

更新日期：2010-01-01 00:00:00

abstract：:There is A paucity of data on racial differences in epidemiology of irritable bowel syndrome (IBS) alone and un-investigated dyspepsia (UD) alone compared to "overlap syndrome" (OS). We conducted a random survey (n = 990). Subjects completed a questionnaire which included Rome II criteria for IBS and functional dyspep...

journal_title：Digestive diseases and sciences

authors： Minocha A,Chad W,Do W,Johnson WD

更新日期：2006-01-01 00:00:00

abstract：:Hereditary type 2 diabetes mellitus is a risk factor for chronic liver disease, and ~30 % of patients with liver cirrhosis develop diabetes. Diabetes mellitus has been associated with cirrhotic and non-cirrhotic hepatitis C virus liver infection, can aggravate the course the liver infection, and can induce a lower sus...

journal_title：Digestive diseases and sciences

authors： García-Compeán D,González-González JA,Lavalle-González FJ,González-Moreno EI,Villarreal-Pérez JZ,Maldonado-Garza HJ

更新日期：2016-02-01 00:00:00

abstract：:The macroscopic appearance of the liver after primary portal vein thrombosis often mimics cirrhosis, despite the absence of bridging fibrosis at histology. The purpose of this study was to describe unique morphologic changes of the liver after portal venous thrombosis. A retrospective review was performed to find pati...

journal_title：Digestive diseases and sciences

authors： Tublin ME,Towbin AJ,Federle MP,Nalesnik MA

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:We investigated the effects of ischemia/reperfusion in the intestine (I/R-i) on purine receptor P2X2-immunoreactive (IR) neurons of the rat ileum. METHODS:The superior mesenteric artery was occluded for 45 min with an atraumatic vascular clamp and animals were sacrificed 4 h later. Neurons of the myenteric and...

journal_title：Digestive diseases and sciences

authors： Paulino AS,Palombit K,Cavriani G,Tavares-de-Lima W,Mizuno MS,Marosti AR,da Silva MV,Girotti PA,Liberti EA,Castelucci P

更新日期：2011-08-01 00:00:00

abstract：:Both increased duodenogastric reflux and chronic aspirin ingestion are associated with the development of gastric ulcers in man. Animal studies suggest aspirin increases duodenogastric reflux. Prostaglandin E2 protects gastric mucosa from the effects of many injurious agents and inhibits gastric motility, but its effe...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Mello WD,Valenzuela JE

更新日期：1985-06-01 00:00:00

abstract：:Ischemic enterocolitis is a well-recognized entity occurring in cocaine users. Diagnosis is based on the presence of rectal bleeding, abdominal pain, a history of cocaine use, supportive endoscopic and histopathologic findings, and the absence of other etiologic mechanisms of ischemic colitis. In this study, we evalua...

journal_title：Digestive diseases and sciences

authors： Niazi M,Kondru A,Levy J,Bloom AA

更新日期：1997-07-01 00:00:00

abstract：:Experimental graft-versus-host disease (GVHD) causes immune-mediated intestinal injury. The adhesion molecule lymphocyte function associated antigen-1 (LFA-1) is involved in leukocyte homing to areas of inflammatory injury. Our hypothesis was that LFA-1 is increased in the GVHD injured small bowel and colon. We found ...

journal_title：Digestive diseases and sciences

authors： Poritz LS,Olt GJ,Ruggiero FM,Colony P,Tilberg AF,Koltun WA

更新日期：1998-02-01 00:00:00