MiR-27a/b Regulates Liver Regeneration by Posttranscriptional Modification of Tmub1.

abstract：:The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 microgram/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. ...

journal_title：Digestive diseases and sciences

authors： Maekubo H,Matsushima T,Okada F,Honma M,Ui M

更新日期：1980-09-01 00:00:00

abstract：:Gastric antral vascular ectasia was endoscopically diagnosed in seven patients. Pathologic characteristics of this entity were defined retrospectively, by studying endoscopic pinch biopsy slides from these seven patients and antrectomy specimens from five patients. A scoring system was developed, and the seven patient...

journal_title：Digestive diseases and sciences

authors： Gilliam JH 3rd,Geisinger KR,Wu WC,Weidner N,Richter JE

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

journal_title：Digestive diseases and sciences

authors： Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Although the mortality rates for non-variceal upper gastrointestinal bleeding (NVUGIB) have recently decreased, it remains a significant medical problem. AIM:The main aim of this prospective multicenter database study was to construct a clinically useful predictive scoring system by using our predictors and...

journal_title：Digestive diseases and sciences

authors： Hwang S,Jeon SW,Kwon JG,Lee DW,Ha CY,Cho KB,Jang B,Park JB,Park YS,Daegu-Gyengbuk Gastrointestinal Study Group (DGSG).

更新日期：2016-07-01 00:00:00

abstract：:Previous studies have shown that duodenal motility patterns differ in preterm and term infants, but antral motor activities were not compared. Using a validated, low-compliance, continuous-perfusion, neonatal manometric system, antral and duodenal motility was studied in 19 preterm and nine term infants. Antral motili...

journal_title：Digestive diseases and sciences

authors： Ittmann PI,Amarnath R,Berseth CL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00

abstract：:A muscarinic receptor subtype 1 (M1) antagonist, pirenzepine, recently has been shown to be relatively free of the usual anticholinergic side effects on esophageal smooth muscle and thus has been implicated for the treatment of gastroesophageal reflux disease (GERD). However, the effect of pirenzepine on GERD remains ...

journal_title：Digestive diseases and sciences

authors： Sato TL,Wu WC,Castell DO

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown. AIMS:Th...

journal_title：Digestive diseases and sciences

authors： Im JP,Ye BD,Kim JM,Jung HC,Song IS,Kim JS

更新日期：2011-08-01 00:00:00

abstract：:We measured suprahepatic vein and arterial partial oxygen pressure in 35 alcoholics with severe (N = 7) or mild (N = 28) histological liver damage and without evidence of clinical liver failure. The suprahepatic vein was punctured with a fine needle, using a percutaneous approach. Suprahepatic vein partial oxygen pres...

journal_title：Digestive diseases and sciences

authors： Bunout D,Moya P,de la Maza MP,Petermann M,Iturriaga H,Hirsch S

更新日期：1995-06-01 00:00:00

abstract：:This study evaluates the hypothesis that cerulein relaxes the sphincter of Oddi (SO) via nitric oxide (NO). The spontaneous motility and the response to cerulein on the canine SO were recorded using a constant-perfusion technique. N(G)-L-arginine-methyl-ester (L-NAME) increased the spontaneous motility and dose-depend...

journal_title：Digestive diseases and sciences

authors： Shima Y,Mori M,Harano M,Tsuge H,Tanaka N,Yamazato T

更新日期：1998-03-01 00:00:00

abstract：:Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...

journal_title：Digestive diseases and sciences

authors： Davis GL,Krawczynski K,Szabo G

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in affluent countries. Recent studies have reported that circular RNAs (circRNAs) are important regulators of hepatic steatosis. However, the role and mechanism of circRNA in NAFLD are poorly understood. AIMS:This study is to ...

journal_title：Digestive diseases and sciences

authors： Li P,Shan K,Liu Y,Zhang Y,Xu L,Xu L

更新日期：2019-01-01 00:00:00

abstract：:Assessment of disease activity by clinical parameters in ulcerative colitis is still controversial. Different clinical indexes have been proposed. Colonoscopy provides detailed information on mucosal damage. The aim of this study was to identify, among 21 clinical and laboratory parameters, which were predictive of en...

journal_title：Digestive diseases and sciences

authors： Azzolini F,Pagnini C,Camellini L,Scarcelli A,Merighi A,Primerano AM,Bertani A,Antonioli A,Manenti F,Rigo GP

更新日期：2005-02-01 00:00:00

abstract：:During topical dissolution of gallstones, solvent can escape to the duodenum causing toxic effects that have not yet been adequately quantified. We compared the local intestinal cytotoxic and systemic hepatotoxic effects of two gallstone solvents, methyl tert-butyl ether and ethyl propionate, on the rabbit's duodenum....

journal_title：Digestive diseases and sciences

authors： Clerici C,Gentili G,Zakko SF,Balò S,Miglietti M,Giansanti M,Modesto R,Guttermuth CF,Morelli A

更新日期：1997-03-01 00:00:00

abstract：:Isosmotic liquid peptone meals adjusted to pH 7, 3, and 1.5 were instilled on separate days into the stomachs of 8 duodenal ulcer patients and 7 healthy controls. Using a marker-dilution method, duodenal acid load (DAL) was measured as the amount of unbuffered hydrogen ions delivered to the duodenum per unit time. Gas...

journal_title：Digestive diseases and sciences

authors： Lam SK,Isenberg JI,Grossman MI,Lane WH,Hogan DL

更新日期：1982-07-01 00:00:00

abstract：:The results of 88 consecutive small-bowel enemas were compared retrospectively with the results of 52 routine small-bowel series and 50 barium enemas done in the same patients. Ninety-six percent of the diagnoses made by small-bowel enema were correct, as compared to only 65% made by routine small-bowel series. The in...

journal_title：Digestive diseases and sciences

authors： Gurian L,Jendrzejewski J,Katon R,Bilbao M,Cope R,Melnyk C

更新日期：1982-12-01 00:00:00

abstract：:Nonalcoholic steatohepatitis is the fastest-growing indication for the liver transplant and a leading cause of hepatocellular carcinoma among patients listed for liver transplantation in the USA. Post-transplant nonalcoholic hepatic steatosis and steatohepatitis are frequent complications of liver transplantation. Non...

journal_title：Digestive diseases and sciences

authors： Samji NS,Verma R,Keri KC,Singal AK,Ahmed A,Rinella M,Bernstein D,Abdelmalek MF,Satapathy SK

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:There is a large Barrett's esophagus patient population undergoing endoscopic surveillance. Methods to stratify patients into higher and lower risk groups may enable more varied surveillance intervals for patients with non-dysplastic Barrett's esophagus that could optimize use of endoscopy resources. OBJECT...

journal_title：Digestive diseases and sciences

authors： Kunzmann AT,Coleman HG,Johnston BT,Turkington RC,McManus D,Anderson LA,Thrift AP

更新日期：2020-07-20 00:00:00

abstract：:This article [1] is retracted at the request of Editor-in-Chief. ...

journal_title：Digestive diseases and sciences

authors： Zong G,Xu Z,Zhang S,Shen Y,Qiu H,Zhu G,He S,Tao T,Chen X

更新日期：2019-11-11 00:00:00

abstract：:The role of mast cells, potential mediators of mucosal immunity and inflammation, was studied morphologically in the rectal mucosa in two acute diarrheal diseases, cholera and shigellosis. Quantitation of mucosal mast cells showed that they were significantly higher in the deeper lamina propria where blood vessels and...

journal_title：Digestive diseases and sciences

authors： Pulimood AB,Mathan MM,Mathan VI

更新日期：1998-09-01 00:00:00

abstract：:Nongranulomatous chronic idiopathic enterocolitis is characterized by sudden onset of severe watery diarrhea, malabsorption, exudative enteropathy, frequent appearance of shallow ulcerations, and variable degrees of villus atrophy. In the absence of infectious and pharmacologic causes, the presence of a predominantly ...

journal_title：Digestive diseases and sciences

authors： Soergel KH

更新日期：2000-11-01 00:00:00

abstract：:Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supplemented with 0.2% DOC, develop colonic inflammation associated with in...

journal_title：Digestive diseases and sciences

authors： Bernstein H,Holubec H,Bernstein C,Ignatenko NA,Gerner E,Dvorak K,Besselsen D,Blohm-Mangone KA,Padilla-Torres J,Dvorakova B,Garewal H,Payne CM

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess safety, efficacy, and clinical outcomes following transcatheter arterial embolization (TAE) of acute gastrointestinal (GI) bleeding. MATERIALS AND METHODS:Ninety-five patients (male:female ratio = 53:42, mean age 62 years) that underwent 95 TAEs for GI hemorrhage between...

journal_title：Digestive diseases and sciences

authors： Yap FY,Omene BO,Patel MN,Yohannan T,Minocha J,Knuttinen MG,Owens CA,Bui JT,Gaba RC

更新日期：2013-07-01 00:00:00

abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...

journal_title：Digestive diseases and sciences

authors： Sandler RS,Johnson MD,Holland KL

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND AND AIM:Negative association has been reported between presence of Helicobacter pylori and developing gastroesophageal reflux disease (GERD) and its complications. The aim of this study was to determine whether H. pylori (HP) can be protective against GERD in an African American (AA) population. METHODS:Fro...

journal_title：Digestive diseases and sciences

authors： Ashktorab H,Entezari O,Nouraie M,Dowlati E,Frederick W,Woods A,Lee E,Brim H,Smoot DT,Ghadyari F,Kamangar F,Razjouyan H

更新日期：2012-11-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) activity has been associated with mucosal growth and injury, yet, little information is available on ODC activity during gastric ulcer healing. We measured ODC activity in the ulcer base submucosa and the surrounding mucosa at 1 cm and 2 cm and assessed ulcer surface healing and a histolo...

journal_title：Digestive diseases and sciences

authors： Marcuard SP,Silverman JF,Finley JL,Seidel ER

更新日期：1992-07-01 00:00:00

abstract：:In previous studies, the majority of patients with the cholestatic liver diseases, primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), had increased hepatic copper (Cu) levels even in early stages of disease. We prospectively measured hepatic copper content by atomic absorption spectrophotometry ...

journal_title：Digestive diseases and sciences

authors： Kowdley KV,Knox TA,Kaplan MM

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:We investigated the effects of ischemia/reperfusion in the intestine (I/R-i) on purine receptor P2X2-immunoreactive (IR) neurons of the rat ileum. METHODS:The superior mesenteric artery was occluded for 45 min with an atraumatic vascular clamp and animals were sacrificed 4 h later. Neurons of the myenteric and...

journal_title：Digestive diseases and sciences

authors： Paulino AS,Palombit K,Cavriani G,Tavares-de-Lima W,Mizuno MS,Marosti AR,da Silva MV,Girotti PA,Liberti EA,Castelucci P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Sigmoid volvulus is a common condition in elderly patients with elongated colons. Although endoscopic de-torsion is effective as the primary treatment of sigmoid volvulus, elective surgery is recommended because of the high risk of recurrence and high mortality rate. AIM:The aim of this study was to determi...

journal_title：Digestive diseases and sciences

authors： Kusunoki R,Fujishiro H,Miyake T,Suemitsu S,Kataoka M,Fujiwara A,Tsukano K,Kotani S,Yamanouchi S,Aimi M,Tanaka M,Miyaoka Y,Kohge N,Imaoka T,Yuasa K,Kodama K,Ishihara S,Kinoshita Y

更新日期：2020-05-14 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00