Nongranulomatous chronic idiopathic enterocolitis: a primary histologically defined disease.

Abstract:

:Nongranulomatous chronic idiopathic enterocolitis is characterized by sudden onset of severe watery diarrhea, malabsorption, exudative enteropathy, frequent appearance of shallow ulcerations, and variable degrees of villus atrophy. In the absence of infectious and pharmacologic causes, the presence of a predominantly acute inflammatory infiltrate limited to the lamina propria establishes the diagnosis. No underlying disease appears during prolonged follow-up. The etiology remains unknown. The disease is generally corticosteroid-responsive; low-dose maintenance therapy is frequently required. The long-term prognosis is guarded. Three of 11 patients died of opportunistic infections or resistance to therapy.

journal_name

Dig Dis Sci

authors

Soergel KH

doi

10.1023/a:1026415218942

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

2085-90

issue

11

eissn

0163-2116

issn

1573-2568

journal_volume

45

pub_type

杂志文章,评审
  • Effects of sennosides on colonic myoelectrical activity in man.

    abstract::The effects of sennosides on colonic myoelectrical activity were investigated in man. Spiking activity of the left and sigmoid colons was continuously recorded in seven constipated patients during two sessions from 5:00 PM to 9:00 AM. Each patient received orally at 7:00 PM on two consecutive days 30 mg of sennosides ...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01536053

    authors: Frexinos J,Staumont G,Fioramonti J,Bueno L

    更新日期:1989-02-01 00:00:00

  • Effect of eradication of Helicobacter pylori infection on gastric epithelial cell proliferation.

    abstract::Helicobacter pylori infection has been linked with gastric carcinoma. Epithelial cell proliferation is an indicator of cancer risk. The aim of this study was to assess gastric epithelial cell proliferation before and after eradication therapy and to assess the efficacy of treatment of H. pylori infection using lanzopr...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02212681

    authors: Cahill RJ,Xia H,Kilgallen C,Beattie S,Hamilton H,O'Morain C

    更新日期:1995-08-01 00:00:00

  • Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas.

    abstract::Impairment of pancreatic microcirculation has often been advocated as one pathogenic mechanism in necrotizing pancreatitis. In contrast, data on pancreatic capillary perfusion in edematous pancreatitis are scarce. It was the aim of this experimental study to compare changes in pancreatic microcirculation in edematous ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02087702

    authors: Klar E,Schratt W,Foitzik T,Buhr H,Herfarth C,Messmer K

    更新日期:1994-12-01 00:00:00

  • Perception of gastric distension. Influence of mode of distension on perception thresholds and gastric compliance.

    abstract::Gastric distension has been used to evaluate gastric sensory function in humans, but the methodology is poorly validated and studies in vivo comparing different distension protocols are lacking. We aimed to compare the influence of the mode of gastric distension on sensation and gastric compliance utilizing a barostat...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF02220459

    authors: Holtmann G,Gschossmann J,Guerra G,Goebell H,Talley NJ

    更新日期:1995-12-01 00:00:00

  • Nutritional implications of chronic dyspepsia in childhood.

    abstract::Chronic dyspepsia is common in children. However, the association of individual predominant symptoms with gastric emptying and their impact on nutritional status are poorly defined. We therefore studied 31 children (mean age 11 years, 14 boys) with chronic dyspepsia and classified their predominant symptoms (PS) by th...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1013299016879

    authors: Papadopoulou A,Vazeou A,Siafakas C,Papadimitriou A,Bartsocas C

    更新日期:2002-01-01 00:00:00

  • Intense nutritional support in inflammatory bowel disease.

    abstract::The value of intense nutritional support in inflammatory bowel disease is still debated. Claims have been made that total enteral nutrition is as effective as total parental nutrition. In this review, the use of parenteral and enteral nutritional support as primary therapy in patients with inflammatory bowel disease h...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/BF02064990

    authors: Wu S,Craig RM

    更新日期:1995-04-01 00:00:00

  • Inhibitory effect of emodin on tissue inhibitor of metalloproteinases-1 (TIMP-1) expression in rat hepatic stellate cells.

    abstract::Emodin inhibited expression of both transforming growth factor beta1 (TGFbeta1)- and phorbol ester (PMA)-induced tissue inhibitors of metalloproteinase-1 (TIMP-1) in an immortalized rat hepatic stellate cell line, HSC-T6, by Western blot and reverse transcription polymerase chain reaction. Reporter gene assays showed ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-006-9321-z

    authors: Gui M,Zhang YF,Xiao ZY,Sun P,Dai JF,Wang SF,Rui YC,Zhang JP

    更新日期:2007-01-01 00:00:00

  • Prevalence of esophageal eosinophilia and eosinophilic esophagitis in adults: a population-based endoscopic study in Shanghai, China.

    abstract:BACKGROUND AND AIM:Population-based endoscopic studies of esophageal eosinophilia and eosinophilic esophagitis are limited in the world. This study was aiming to describe features of esophageal eosinophilia and eosinophilic esophagitis in a representative sample of the adult in Shanghai, China. METHODS:As part of a la...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3512-9

    authors: Ma X,Xu Q,Zheng Y,Zhao Y,Lu J,Wang R,Li Z,Zou D,He J

    更新日期:2015-06-01 00:00:00

  • Factors affecting methane production in humans. Gastrointestinal diseases and alterations of colonic flora.

    abstract::Breath methane was studied in 394 subjects. Among 152 controls, 50.0% produced methane--42.1% of males and 57.9% of females. One hundred sixteen patients with gastrointestinal diseases were studied. Among 32 with Crohn's disease, only 2 (6.1%) produced methane, as well as 16 of 51 ulcerative colitis patients (31.4%) a...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01297052

    authors: Peled Y,Weinberg D,Hallak A,Gilat T

    更新日期:1987-03-01 00:00:00

  • Development and validation of the Gastroesophageal Reflux Disease Treatment Satisfaction Questionnaire.

    abstract::There is growing recognition of the importance of assessing patient perceptions of treatment, especially patient satisfaction. The Gastroesophageal Reflux Disease (GERD) Treatment Satisfaction Questionnaire (GTSQ) was developed to assess satisfaction with GERD medication. A web-based survey, which included the GTSQ an...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-3002-1

    authors: Shikiar R,Flood E,Siddique R,Howell J,Dodd SL

    更新日期:2005-11-01 00:00:00

  • Immunomodulation of transplant rejection using monoclonal antibodies and soluble receptors.

    abstract::The main objective of our studies has been to optimize the effects of monoclonal antibodies (MAbs) and other immunosuppressive reagents to enhance organ graft survival. One such agent is OKT3, a MAb that is directed against the CD3 component of the human T-cell receptor (TCR) complex. Treatment of a rejection episode ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/BF02063942

    authors: Alegre ML,Lenschow DJ,Bluestone JA

    更新日期:1995-01-01 00:00:00

  • Are the echogenicities on intraductal ultrasonography really biliary microlithiasis?

    abstract:BACKGROUND:Intraductal ultrasonography (IDUS) is a useful procedure for diagnosing microlithiasis in the bile duct but it is not easy to differentiate between tiny echogenicity and real microlithiasis. We compared the echogenicity seen on IDUS and the findings of bile microscopy (BM) of bile that was collected in the c...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-009-0770-z

    authors: Kim BJ,Kang P,Lee JK,Sinn DH,Lee KH,Lee KT,Rhee JC,Lim JH

    更新日期:2010-03-01 00:00:00

  • Frailty Assessment Predicts Acute Outcomes in Patients Undergoing Screening Colonoscopy.

    abstract:BACKGROUND:Colonoscopy is associated with multiple adverse outcomes. With an aging population undergoing colorectal cancer screening, few modalities exist to assess the patient risk prior to colonoscopy. Frailty, the age-related decline in reserve and function across multiple organ systems, predicts poor surgical outco...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-5129-x

    authors: Taleban S,Toosizadeh N,Junna S,Golden T,Ghazala S,Wadeea R,Tirambulo C,Mohler J

    更新日期:2018-12-01 00:00:00

  • Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying.

    abstract:BACKGROUND AND AIM:Diabetes is the main cause of gastroparesis accompanying decreased neuronal nitric oxide synthase (nNOS) in myenteric ganglia of the stomach. Decreased nNOS expression in the stomach also results from defects in apolipoprotein E (ApoE), which is secreted by astrocytes and has neuroprotective effects ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-017-4820-7

    authors: Fukuhara S,Masaoka T,Nishimura S,Nakamura M,Matsuzaki J,Tsugawa H,Miyoshi S,Mori H,Kawase S,Shibata S,Okano H,Kanai T,Suzuki H

    更新日期:2017-12-01 00:00:00

  • Psychological comparison of patients with nutcracker esophagus and irritable bowel syndrome.

    abstract:UNLABELLED:Recent evidence suggests that psychological factors may affect esophageal as well as intestinal motility. To study this further, we compared the psychological profiles of 20 irritable bowel patients and 20 patients with recurrent noncardiac chest pain associated with high-amplitude peristaltic contractions i...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01300697

    authors: Richter JE,Obrecht WF,Bradley LA,Young LD,Anderson KO

    更新日期:1986-02-01 00:00:00

  • Hepatocellular carcinoma screening rates vary by etiology of cirrhosis and involvement of gastrointestinal sub-specialists.

    abstract:BACKGROUND:Regular screening of cirrhotic patients for hepatocellular carcinoma (HCC) has been suboptimal, but there is little data regarding specific risk factors for reduced screening. METHODS:From 1996 to 2010, patients with cirrhosis were retrospectively identified from outpatient gastroenterology and primary care...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-011-1836-2

    authors: Patwardhan V,Paul S,Corey KE,Mazhar SM,Richter JM,Thiim M,Chung RT

    更新日期:2011-11-01 00:00:00

  • Short-Term Effects of Relamorelin on Descending Colon Motility in Chronic Constipation: A Randomized, Controlled Trial.

    abstract:BACKGROUND:The pentapeptide ghrelin agonist, relamorelin, accelerates colonic transit in patients with chronic constipation (CC). In a murine model, relamorelin decreased excitability of colonic circular smooth muscle cells and colonic intraluminal pressure. AIM:To determine short-term effects of relamorelin on coloni...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10620-015-3876-5

    authors: Acosta A,Camilleri M,Busciglio I,Boldingh A,Nelson AD,Burton D

    更新日期:2016-03-01 00:00:00

  • Disseminated aseptic abscesses associated with Crohn's disease: a new entity?

    abstract::Our purpose is to describe seven cases of disseminated aseptic abscesses with regard to clinical, biological, radiological, and histological information, treatment, and outcome. Data were collected on seven Caucasian patients who had proven sterile deep abscesses diagnosed in French university hospitals. The onset of ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018835228850

    authors: André M,Aumaître O,Papo T,Kemeny JL,Vital-Durand D,Rousset H,Ninet J,Pointud P,Charlotte F,Godeau B,Schmidt J,Marcheix JC,Piette JC

    更新日期:1998-02-01 00:00:00

  • Proliferating cell nuclear antigen expression in peribiliary glands of stone-containing intrahepatic bile ducts.

    abstract::All cases of hepatolithiasis showed features of chronic proliferative cholangitis, and it has been speculated that the atypical glandular proliferation might be a precursor to overt cholangiocarcinoma. Proliferative cell nuclear antigen (PCNA) is a nuclear protein synthesized in the G1/S phase of the cell cycle and th...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026604704029

    authors: Lee KT,Sheen PC

    更新日期:1999-11-01 00:00:00

  • Vitamin D deficiency and corticosteroid use are risk factors for low bone mineral density in inflammatory bowel disease patients.

    abstract:BACKGROUND:As several factors can contribute to low bone mineral density (BMD), we investigated the role of vitamin D in low BMD while controlling for other risk factors in inflammatory bowel diseases (IBD) patients. METHODS:We conducted a prospective cross-sectional study between 2008 and 2012 in adult IBD patients. ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3102-x

    authors: Abraham BP,Prasad P,Malaty HM

    更新日期:2014-08-01 00:00:00

  • Intravenous versus high-dose oral proton pump inhibitor therapy after endoscopic hemostasis of high-risk lesions in patients with acute nonvariceal upper gastrointestinal bleeding.

    abstract::Intravenous proton pump inhibitors (IV PPIs) decrease rebleeding following endoscopic hemostasis of bleeding peptic ulcers. Oral PPIs may be equally efficacious and may significantly reduce health care costs. This study aimed to compare outcomes in patients receiving oral versus IV PPI therapy following endoscopic hem...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-006-9684-1

    authors: Murthy S,Keyvani L,Leeson S,Targownik LE

    更新日期:2007-07-01 00:00:00

  • Type 1 autoimmune hepatitis in Taiwan: diagnosis using the revised criteria of the International Autoimmune Hepatitis Group.

    abstract::Autoimmune hepatitis (AIH) is rare in Asian countries compared to the West, and an exceptionally low prevalence was noted previously in Taiwan. Using the revised criteria of the IAIHG, 48 cases of AIH patients were diagnosed. All patients were consecutively diagnosed over a period of 5 years. Detailed medical historie...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-9068-y

    authors: Koay LB,Lin CY,Tsai SL,Lee C,Lin CN,Sheu MJ,Kuo HT,Sun CS

    更新日期:2006-11-01 00:00:00

  • Food-Induced Acute Pancreatitis.

    abstract::Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-017-4817-2

    authors: Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

    更新日期:2017-12-01 00:00:00

  • Leptin in the field of hepatic fibrosis: a pivotal or an incidental player?

    abstract::Leptin is a 16-kDa nonglycosylated protein primarily secreted from the adipocytes of white fat; minor levels of regulated leptin expression also occurs at other sites such as placenta, skeletal muscle, the stomach fundus, and culture-activated hepatic stellate cells (HSCs). Leptin is primarily involved in the regulati...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-006-9126-0

    authors: Bethanis SK,Theocharis SE

    更新日期:2006-10-01 00:00:00

  • Subtotal colectomy for severe idiopathic constipation. A follow-up study of 13 patients.

    abstract::We obtained follow-up information on 13 patients who underwent subtotal colectomy for severe idiopathic constipation 19-45 months previously. Stool frequency increased from one bowel movement per 11.5 days before colectomy to 5.3 bowel movements per day after colectomy. Nine patients have required readmissions for abd...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296374

    authors: Leon SH,Krishnamurthy S,Schuffler MD

    更新日期:1987-11-01 00:00:00

  • A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome.

    abstract:PURPOSE:The objectives of this study were, firstly, to determine the diversity of the host's gut microbiota in irritable bowel syndrome (IBS) using a culture-independent method (DGGE of the 16S rRNA gene) and, secondly, to examine mucosal biopsies of IBS patients and compare them to their own fecal microbiota. METHODS...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-009-0934-x

    authors: Codling C,O'Mahony L,Shanahan F,Quigley EM,Marchesi JR

    更新日期:2010-02-01 00:00:00

  • Effects of stimulation and inhibition of acid secretion on gastric damage induced by platelet-activating factor.

    abstract::Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296615

    authors: Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

    更新日期:1991-12-01 00:00:00

  • Antimony electrodes. Mucosal potential differences and buffer composition adversely affect pH measurements in the stomach.

    abstract::Antimony electrodes are clinically useful because of their low cost and simple construction; they have no glass to break. There is only a few hundred ohms resistance between an antimony pH electrode and the reference electrode so that the voltage generated can be recorded with simple low-impedance recorders linked to ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01537242

    authors: Opekun AR,Smith JL,Graham DY

    更新日期:1990-08-01 00:00:00

  • Low ERCP Volume Is Associated with More Industry Representative Interactions but Similar Training of Nurses.

    abstract:BACKGROUND:Data on ERCP nurses and associate (ERCP-NA) training and comfort are lacking. Healthcare industry representative (HCIR) influence may be greater in low-volume units (LVUs) due to decreased procedure and device familiarity. AIM:The aim of this study was to compare ERCP-NA training, safety, and HCIR relations...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-015-3926-z

    authors: Keswani RN,Malpas P,Lynch SE,Coté GA

    更新日期:2016-03-01 00:00:00

  • MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer.

    abstract:BACKGROUND:Our previous study has shown that MYO5B is downregulated in gastric cancer. However, the mechanism by which the expression of MYO5B was inhibited remains unknown. METHODS:Inspection of the human MYO5B locus uncovered a large and dense CpG island within the 5' region of this gene. Methylation-specific PCR (M...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-013-2600-6

    authors: Dong W,Wang L,Shen R

    更新日期:2013-07-01 00:00:00