MYO5B is epigenetically silenced and associated with MET signaling in human gastric cancer.

abstract：BACKGROUND AND AIM:Dietary fiber shortens gut transit time, but data on the effects of fiber components (including resistant starch, RS) on intestinal contractility are limited. We have examined RS effects in male Sprague-Dawley rats fed either a high-amylose maize starch (HAMS) or a wholemeal made from high-amylose wh...

journal_title：Digestive diseases and sciences

authors： Patten GS,Kerr CA,Dunne RA,Shaw JM,Bird AR,Regina A,Morell MK,Lockett TJ,Molloy PL,Abeywardena MY,Topping DL,Conlon MA

更新日期：2015-06-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Data on cyclic vomiting syndrome (CVS) are limited to studies from tertiary care centers. There is a paucity of information about CVS on a national scale. AIM:To study the clinical characteristics, comorbidities, and hospital outcomes in patients hospitalized with CVS using a nationwide database. METHODS:W...

journal_title：Digestive diseases and sciences

authors： Bhandari S,Venkatesan T

更新日期：2017-08-01 00:00:00

abstract：:Endoscopic biopsies are being increasingly utilized to investigate cytokine profiles in normal and diseased intestine. To evaluate the adequacy of mucosal biopsies as a source of cytokine-specific mRNA, we measured their content of interleukin-1 beta (IL-1 beta) and interleukin-2 (IL-2) mRNA by reverse transcription-p...

journal_title：Digestive diseases and sciences

authors： Fukushima K,West G,Fiocchi C

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Long non-coding RNAs have been acknowledged as the crucial regulators in the progression of human cancers, including gastric cancer (GC). Small nucleolar RNA host gene 10 (SNHG10) has been identified as an oncogene in several cancer types. Nonetheless, it is unclear whether SNHG10 exerts functions in GC cell...

journal_title：Digestive diseases and sciences

authors： Yuan X,Yang T,Xu Y,Ou S,Shi P,Cao M,Zuo X,Liu Q,Yao J

更新日期：2020-09-12 00:00:00

abstract：:Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...

journal_title：Digestive diseases and sciences

authors： Froehlich F,Hartmann D,Guezelhan C,Gonvers JJ,Jansen JB,Fried M

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder with increasing prevalence. However, epidemiologic data have mostly been acquired from small studies. We sought to describe the epidemiology of EoE in the USA, utilizing a large database. METHODS:We queried a commercial database (Exp...

journal_title：Digestive diseases and sciences

authors： Mansoor E,Cooper GS

更新日期：2016-10-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:The preoperative determination of the localization of a small insulinoma is sometimes difficult using routine imaging techniques. We have used the selective arterial calcium injection (SACI) test to determine the location of the tumor preoperatively. The pathophysiologic basis of the SACI test is based on the responsi...

journal_title：Digestive diseases and sciences

authors： Kato M,Doi R,Imamura M,Okada N,Shimada Y,Hosotani R,Miyazaki JI

更新日期：1998-11-01 00:00:00

abstract：:This study set out to evaluate the effects of dietary fiber on cancer development in the large bowel under in vivo experimental conditions as similar as possible to those under which this cancer develops in vivo in humans. Forty-eight Sprague-Dawley rats were divided into three groups that were fed either a nonfiber d...

journal_title：Digestive diseases and sciences

authors： Iwane S,Nakaji S,Ohta M,Tamura K,Sakamoto J,Munakata A,Sugawara K

更新日期：2002-06-01 00:00:00

abstract：:Fourteen patients with duodenal ulcers and eight healthy volunteers were examined to measure interdigestive gastroduodenal motility and plasma motilin. In order to study the effects of gastric acid on the gastroduodenal motility, 20 mg of famotidine was administered intravenously. The motility index of the gastric ant...

journal_title：Digestive diseases and sciences

authors： Kusano M,Sekiguchi T,Nishioka T,Kawamura O,Kikuchi K,Matsuzaki T,Horikoshi T

更新日期：1993-05-01 00:00:00

abstract：:Motion sickness provides a unique setting for the study of nausea. Studies of illusory self-motion have linked nausea and objective measures of gastric dysrhythmias and the stress hormones vasopressin and epinephrine. Electrogastrographic methods utilize Ag-AgCl electrodes placed on the abdominal surface in the epigas...

journal_title：Digestive diseases and sciences

authors： Koch KL

更新日期：1999-08-01 00:00:00

abstract：:The study aimed to examine the serum serological response among H. pylori-infected patients with various upper gastrointestinal diagnoses; to ascertain whether it could be predictive to the diagnostic outcome of dyspepsia. One hundred seventy H. pylori-infected patients with dyspeptic symptoms but without previous tre...

journal_title：Digestive diseases and sciences

authors： Shiesh SC,Sheu BS,Yang HB,Tsao HJ,Lin XZ

更新日期：2000-04-01 00:00:00

abstract：:Pancreatic function tests were performed in 11 adult cystic fibrosis (CF) patients with a fecal fat excretion of more than 10% during treatment with pancrease 2 capsules three times a day. These tests included urinary p-aminobenzoic acid (PABA) excretion, fasting serum trypsin and pancreatic polypeptide (PP), and gluc...

journal_title：Digestive diseases and sciences

authors： Heijerman HG,Lamers CB,Bakker W,Dijkman JH

更新日期：1993-01-01 00:00:00

abstract：:Helicobacter pylori causes a lifelong infection in the stomach after exposure. H. pylorihas been shown to be associated with peptic ulcer and gastric cancer development. Moreover, it is held responsible for some other nongastric diseases. Among them, coronary heart disease attracts much debate. Many studies have demon...

journal_title：Digestive diseases and sciences

authors： Aydemir S,Bayraktaroglu T,Sert M,Sokmen C,Atmaca H,Mungan G,Gun BD,Borazan A,Ustundag Y

更新日期：2005-11-01 00:00:00

abstract：:We studied the prevalence as well as the sociodemographic characteristics and QOL of older adults (> 50 years) with irritable bowel syndrome (IBS) among the population at large and compared it to their younger counterparts'. We hypothesized that IBS is less prevalent among older persons and they suffer poorer QOL comp...

journal_title：Digestive diseases and sciences

authors： Minocha A,Johnson WD,Abell TL,Wigington WC

更新日期：2006-03-01 00:00:00

abstract：:We retrospectively reviewed the role of ursodeoxycholic acid in infants having nonsurgical cholestasis attending the Hepatology Clinic, New Children Hospital, Cairo University, Egypt, from 1985 until 2005. Files of 496 infants with neonatal hepatitis and 97 with intrahepatic bile duct paucity were included; of them 24...

journal_title：Digestive diseases and sciences

authors： Kotb MA

更新日期：2009-10-01 00:00:00

abstract：:Although systemic steroids remain as the gold standard for the treatment of acute moderate to severe active ulcerative colitis (UC), 15-57% of patients do not achieve clinical remission. We sought to identify clinical, biological, or radiologic predictive factors of response to steroid treatment in acute UC attacks. T...

journal_title：Digestive diseases and sciences

authors： Bernal I,Mañosa M,Domènech E,Garcia-Planella E,Navarro M,Lorenzo-Zúñiga V,Cabré E,Gassull MA

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Hepatic encephalopathy (HE) is considered reversible regarding mental status but may not be cognitively in single-center studies. AIM:To evaluate persistence of learning impairment in prior HE compared to those who never experienced HE (no-HE) in a multicenter study. METHODS:A total of 174 outpatient cirrh...

journal_title：Digestive diseases and sciences

authors： Nardelli S,Allampati S,Riggio O,Mullen KD,Prakash R,Gioia S,Unser A,White MB,Fagan AC,Wade JB,Farcomeni A,Gavis EA,Bajaj JS

更新日期：2017-03-01 00:00:00

abstract：:Ninety-one patients with idiopathic constipation had segmental colonic transit studied with radiopaque markers using a new simplified technique to determine frequency and type of colonic transit time (CTT) abnormalities and to determine the utility of this test in planning therapy. Colonic transit studies defined four...

journal_title：Digestive diseases and sciences

authors： Chaussade S,Khyari A,Roche H,Garret M,Gaudric M,Couturier D,Guerre J

更新日期：1989-08-01 00:00:00

abstract：:Intravenous infusion of platelet-activating factor (PAF-acether) induces extensive vasocongestion and damage in the stomach and small intestine of the rat. The effect of pretreatment with the corticoid dexamethasone (2 mg/kg) on such gastrointestinal damage in the rat has now been investigated, using macroscopic obser...

journal_title：Digestive diseases and sciences

authors： Wallace JL,Whittle BJ

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Previous studies have demonstrated the value of systematic feedback in enhancing endoscopic procedure performance. It remains unknown whether feedback may play a role in modifying physician performance in outpatient practice. This study aimed to assess the impact of systematic feedback on duration o...

journal_title：Digestive diseases and sciences

authors： Harewood GC

更新日期：2011-10-01 00:00:00

abstract：:The aims of our randomized, single-blind trial involving 49 patients were to study the efficacy, side effects, and tolerance of metronidazole and satranidazole in patients of amebic liver abscess. Twenty-five patients received metronidazole (800 mg TID) and 24 received satranidazole (300 mg TID with placebo at mealtim...

journal_title：Digestive diseases and sciences

authors： Muzaffar J,Madan K,Sharma MP,Kar P

更新日期：2006-12-01 00:00:00

abstract：:There is growing recognition of the importance of assessing patient perceptions of treatment, especially patient satisfaction. The Gastroesophageal Reflux Disease (GERD) Treatment Satisfaction Questionnaire (GTSQ) was developed to assess satisfaction with GERD medication. A web-based survey, which included the GTSQ an...

journal_title：Digestive diseases and sciences

authors： Shikiar R,Flood E,Siddique R,Howell J,Dodd SL

更新日期：2005-11-01 00:00:00

abstract：:Helicobacter pylori infection has been linked with gastric carcinoma. Epithelial cell proliferation is an indicator of cancer risk. The aim of this study was to assess gastric epithelial cell proliferation before and after eradication therapy and to assess the efficacy of treatment of H. pylori infection using lanzopr...

journal_title：Digestive diseases and sciences

authors： Cahill RJ,Xia H,Kilgallen C,Beattie S,Hamilton H,O'Morain C

更新日期：1995-08-01 00:00:00

abstract：:Changes in hepatic morphology were evaluated in 242 consecutive liver biopsy specimens obtained from nonalcoholic obese subjects. Steatosis occurred in 59.7% of the subjects but was moderate to severe in 28.7%. An alcoholic hepatitis-like picture was present in 8.7% and cirrhosis in 2.7%. Fibrosis of mild and moderate...

journal_title：Digestive diseases and sciences

authors： Nasrallah SM,Wills CE Jr,Galambos JT

更新日期：1981-04-01 00:00:00

abstract：:Metronidazole has been used to treat pouchitis, but there are no controlled data that show it is effective. Chronic unremitting pouchitis is a form of the disorder particularly difficult to manage. Diarrhea is the main symptom of pouchitis, which results from acute inflammation of the mucosa of an ileal reservoir. To ...

journal_title：Digestive diseases and sciences

authors： Madden MV,McIntyre AS,Nicholls RJ

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Gastric acidification inhibits motilin-induced gastric phase III contractions. However, the underlying mechanism has not been thoroughly investigated. Here, we studied the inhibitory mechanism by gastric acidification on motilin-induced contraction in Suncus murinus (S. murinus). METHODS:We measured interdi...

journal_title：Digestive diseases and sciences

authors： Yoshimura M,Mikami T,Kuroda K,Nishida M,Ito K,Mondal A,Koyama K,Jogahara T,Sakata I,Sakai T

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

journal_title：Digestive diseases and sciences

authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

更新日期：2008-08-01 00:00:00

abstract：:Alterations in both gastric emptying (GE) and small bowel motility have been reported in irritable bowel syndrome (IBS); the relationship, however, between these different measures of upper gut motor function in IBS has not been assessed. The aims of this study were therefore: (1) to compare the prevalence and charact...

journal_title：Digestive diseases and sciences

authors： Evans PR,Bak YT,Shuter B,Hoschl R,Kellow JE

更新日期：1997-10-01 00:00:00