Hepatic morphology in obesity.

Abstract:

:Changes in hepatic morphology were evaluated in 242 consecutive liver biopsy specimens obtained from nonalcoholic obese subjects. Steatosis occurred in 59.7% of the subjects but was moderate to severe in 28.7%. An alcoholic hepatitis-like picture was present in 8.7% and cirrhosis in 2.7%. Fibrosis of mild and moderate degrees was encountered in 26.1% and 5.8%, respectively. This study indicates that the histopathological changes that occur in the livers of obese subjects are similar to alcoholic liver injury.

journal_name

Dig Dis Sci

authors

Nasrallah SM,Wills CE Jr,Galambos JT

doi

10.1007/BF01308373

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

325-7

issue

4

eissn

0163-2116

issn

1573-2568

journal_volume

26

pub_type

杂志文章
  • Microendoscopic nasointestinal feeding tube placement in mechanically ventilated patients with gastroparesis.

    abstract::Gastroparesis often precludes gastric enteral nutrition (EN) in critically ill patients. Our aim was to determine the feasibility of bedside microendoscopic placement of nasointestinal feeding tubes to facilitate enteral nutrition in critically ill patients with poor gastric emptying. Nine mechanically ventilated pati...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1022828507557

    authors: Taylor SJ,Przemioslo R,Manara AR

    更新日期:2003-04-01 00:00:00

  • Natural killer cell activity in patients with pernicious anemia.

    abstract::Patients with pernicious anemia have an estimated risk of gastric adenocarcinoma that ranges from three- to fivefold greater than that of the general population. It has been reported that NK cells may be involved in immunosurveillance against tumor spread. The natural killer cell activity of peripheral blood mononucle...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02285205

    authors: Vargas JA,Alvarez-Mon M,Manzano L,Albillos A,Fernández-Corugedo A,Gea-Banacloche JC,Gonzalez FM,Durántez A

    更新日期:1995-07-01 00:00:00

  • Assessment of gastric emptying: comparison of solid scintigraphic emptying and emptying of radiopaque markers in patients and healthy subjects.

    abstract::The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026609808495

    authors: Stotzer PO,Fjälling M,Grétarsdóttir J,Abrahamsson H

    更新日期:1999-04-01 00:00:00

  • Partial hepatectomy in the treatment of Caroli's disease. Report of a case and review of the literature.

    abstract::We describe a 28-yr-old woman who presented with severe, recurrent cholangitis due to Caroli's disease in association with congenital hepatic fibrosis. Cystic dilatation of the segmental bile ducts was diffuse, but predominated in the right lobe and left medial segment of the liver. Extended right lobectomy was follow...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01318526

    authors: Ramond MJ,Huguet C,Danan G,Rueff B,Benhamou JP

    更新日期:1984-04-01 00:00:00

  • Granulocyte migration in uncomplicated intestinal anastomosis in man.

    abstract::We have investigated the presence, duration, and clinical significance of granulocyte accumulation, using indium-111 granulocyte scanning, in patients following uncomplicated intestinal anastomosis. Eight patients underwent intestinal resection and anastomosis (right hemicolectomy, 5; sigmoid colectomy, 2; ileal resec...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01318118

    authors: Keshavarzian A,Gibson R,Guest J,Spencer J,Lavender JP,Hodgson HJ

    更新日期:1986-03-01 00:00:00

  • Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation.

    abstract::Resistant starch is by definition that part of starch that escapes digestion in the small bowel. Cecal fermentation of resistant starch into short-chain fatty acids will result subsequently in a decrease in pH. Thus, resistant starch may have the same effect on colonic luminal contents and mucosa as some fiber compone...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02087431

    authors: van Munster IP,Tangerman A,Nagengast FM

    更新日期:1994-04-01 00:00:00

  • Gastritic glandularis et cystica profunda: a report of three cases with discussion of etiology and pathogenesis.

    abstract::Three cases of gastritis glandularis et cystica profunda are presented, two associated with severe chronic gastritis and the other with invasive gastric carcinoma and chronic gastritis. This poorly known entity consists of benign downgrowths of deep gastric glands through the muscularis mucosae into the submucosa. The...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01297238

    authors: Honoré LH,Lewis AS,O'Hara KE

    更新日期:1979-01-01 00:00:00

  • Purified micronized flavonoid fraction ameliorates the injury of spleen and ileum secondary to hepatic ischemia-reperfusion in rats.

    abstract:BACKGROUND:Flavonoids have been subjected to considerable investigations due to their antioxidant and anti-inflammatory properties. Yet the effects of flavonoids on the ileum and spleen against hepatic ischemia-reperfusion injury have so far not been addressed. AIMS:We aimed to investigate whether micronized purified ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-009-1018-7

    authors: Yildiz F,Terzi A,Coban S,Bitiren M,Celik H,Aksoy N,Ozdogan MK,Cakir H

    更新日期:2010-08-01 00:00:00

  • Adalimumab Maintenance Treatment in Ulcerative Colitis: Outcomes by Prior Anti-TNF Use and Efficacy of Dose Escalation.

    abstract:BACKGROUND:The impact of prior anti-TNF use on "real-life" outcomes of adalimumab therapy in ulcerative colitis (UC) is not well known. AIM:To compare the influence of prior anti-TNF use on the outcomes of adalimumab maintenance treatment in UC patients. We also assessed the effectiveness of adalimumab dose escalation...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10620-016-4398-5

    authors: Taxonera C,Iglesias E,Muñoz F,Calvo M,Barreiro-de Acosta M,Busquets D,Calvet X,Rodríguez A,Pajares R,Gisbert JP,López-Serrano P,Pérez-Calle JL,Ponferrada Á,De la Coba C,Bermejo F,Chaparro M,Olivares D,Alba C,Fernández

    更新日期:2017-02-01 00:00:00

  • Short-term effects of bile diversion on postgastrectomy gastric histology.

    abstract::Twelve partially gastrectomized subjects who have consecutively undergone total biliary diversion for severe bilious vomiting were studied before and after operation in order to assess the effects of surgery on gastric histology and enterogastric reflux. Before and six months after operation, the following protocol wa...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536682

    authors: Bechi P,Amorosi A,Mazzanti R,Buccarelli A,Pantalone D,Cortesini C

    更新日期:1988-10-01 00:00:00

  • Gastrointestinal effects of long-term colchicine therapy in patients with recurrent polyserositis (familial mediterranean fever).

    abstract::Twelve patients with recurrent polyserositis (RP, familial Mediterranean fever) on colchicine prophylaxis (1.0-2.0 mg daily) for three years or more were evaluated for the presence of gastrointestinal effects possibly attributable to the drug. Two patients had bulky stools, two others had transient diarrhea, and one h...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01393768

    authors: Ehrenfeld M,Levy M,Sharon P,Rachmilewitz D,Eliakim M

    更新日期:1982-08-01 00:00:00

  • Influence of Obesity and Metabolic Abnormalities on the Risk of Developing Colorectal Neoplasia.

    abstract:BACKGROUND:Obesity and metabolic syndrome are risk factors for colorectal neoplasia (CRN). However, the association between metabolically healthy obese (MHO) or metabolically unhealthy non-obese (MUNO) status and the risk of CRN remains unclear. AIMS:We aimed to elucidate the association between MHO or MUNO status and...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-5239-5

    authors: Kim NH,Jung YS,Park JH,Park DI,Sohn CI

    更新日期:2018-11-01 00:00:00

  • Rehospitalization, Treatment, and Resource Use After Inpatient Admission for Achalasia in the USA.

    abstract:INTRODUCTION:Readmission for achalasia treatment is associated with significant morbidity and cost. Factors predictive of readmission would be useful in identifying patients at risk. METHODS:We performed a retrospective study using the Nationwide Readmission Database for the year 2016 and 2017. We collected data on ho...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-020-06775-5

    authors: Gupta K,Khan A,Chalhoub J,Groudan K,Desilets D

    更新日期:2021-01-01 00:00:00

  • Medical residents' colorectal cancer screening may be dependent on ambulatory care education.

    abstract::Colorectal cancer results in significant morbidity and mortality in the United States. Screening is a critical component of cancer prevention. However, research has suggested that physicians may inconsistently adhere to surveillance guidelines. Since residency training can significantly impact upon future practice pat...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018837603989

    authors: Borum ML

    更新日期:1997-06-01 00:00:00

  • Localized amyloid tumor in small bowel.

    abstract::We report a case of localized jejunal amyloidosis occurring in a 74-year-old man who experienced an episode of digestive bleeding while he was receiving oral anticoagulation. It illustrates a rare entity, characterized by an endoscopic aspect of polypoid, pseudotumoral formations. Histologically, submucosal connective...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1005536901678

    authors: Peny MO,Debongnie JC,Haot J,Van Gossum A

    更新日期:2000-09-01 00:00:00

  • Correction to: Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain.

    abstract::The original version of this article unfortunately contained an error in a couple of reference citation in Discussion Section, paragraph 6. The reference citation number should be changed from [6] to [9] in the below sentences so that it reads. ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s10620-018-5046-z

    authors: Hammer V,Hammer K,Memaran N,Huber WD,Hammer K,Hammer J

    更新日期:2018-06-01 00:00:00

  • Light chain deposition disease of the liver without renal involvement in a patient with multiple myeloma related to liver failure and rapid fatal outcome.

    abstract::We describe a 36-year-old man with advanced multiple myeloma (Salmon and Durie stage III) who developed jaundice and severe cholestasis after a first cure with systemic chemotherapy of vincristine, doxorubicin, and oral dexamethasone (VAD). Serology for hepatitis A, B, and C and for CMV was negative. A liver ultrasoun...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1014773512707

    authors: Michopoulos S,Petraki K,Petraki C,Dimopoulos MA

    更新日期:2002-04-01 00:00:00

  • Triolein breath test of fat absorption in patients with chronic liver disease.

    abstract::We have compared the [14C]triolein breath test for fat malabsorption with fecal fat excretion corrected for marker pellet recovery in 23 subjects with chronic liver disease. The breath test identified 15 of the 17 subjects with abnormal fecal fat excretion (sensitivity 88%). However, four of the six subjects with norm...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01798358

    authors: Absalom SR,Saverymuttu SH,Maxwell JD,Levin GE

    更新日期:1988-05-01 00:00:00

  • Changes in serum hepatitis C virus RNA titer and response to interferon therapy in patients with chronic hepatitis C.

    abstract::Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02090379

    authors: Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

    更新日期:1994-10-01 00:00:00

  • Mucosal addressin cell adhesion molecule-1 of rhesus macaques: molecular cloning, expression, and alteration after viral infection.

    abstract:BACKGROUND:Mucosal addressin cell adhesion molecule-1 (MAdCAM-1), a member of the immunoglobulin superfamily, is essential for gut-specific homing of leukocytes; however, it has not been well characterized in rhesus macaques. AIMS:To obtain the complete nucleotide sequence of rhesus macaque MAdCAM-1 cDNA and determine...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3209-0

    authors: Wang Y,Yao WR,Duan JZ,Xu W,Yang GB

    更新日期:2014-10-01 00:00:00

  • Long-Term Outcomes and Predictors of Sustained Response in Patients with Intestinal Behcet's Disease Treated with Infliximab.

    abstract:BACKGROUND:Intestinal Behcet's disease (BD) is a specific subtype of BD. Effective drug therapy for intestinal BD remains elusive. AIMS:To investigate long-term outcomes and identify predictors of sustained response in intestinal BD patients receiving infliximab (IFX) treatment. METHODS:The medical records were revie...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-016-4395-8

    authors: Zou J,Ji DN,Cai JF,Guan JL,Bao ZJ

    更新日期:2017-02-01 00:00:00

  • Is there a relation between irritable Bowel syndrome and urinary stone disease?

    abstract::Our aim was to investigate the role of renal colic, a clinical condition characterized by excruciating pain, in the etiopathogenesis of irritable bowel syndrome (IBS). Two groups of patients were enrolled in the study. Group I consisted of 59 patients (33 male and 26 female) with a median age of 41.9 (18 to 58) years....

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-2482-3

    authors: Erdem E,Akbay E,Sezgin O,Doruk E,Canpolat B,Cayan S

    更新日期:2005-03-01 00:00:00

  • Cisapride vs metoclopramide. An acute study in diabetic gastroparesis.

    abstract::Radionuclide gastric solid-phase emptying was studied in 10 subjects with diabetic gastroparesis comparing the acute intravenous administration of cisapride (2.5, 5, 10 mg), placebo, and metoclopramide (10 mg). No hemodynamic or electrocardiographic changes were noted. While both cisapride and metoclopramide normalize...

    journal_title:Digestive diseases and sciences

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF01300277

    authors: McHugh S,Lico S,Diamant NE

    更新日期:1992-07-01 00:00:00

  • Effect of renal failure or portacaval shunt on release of neurotensin in man.

    abstract::Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296684

    authors: Eaves ER,Hansky J

    更新日期:1987-01-01 00:00:00

  • Focal ultrasound lesions in liver cirrhosis diagnosed as regenerating nodules by fine-needle biopsy. Follow-up of 12 cases.

    abstract::In the period 1985-1988, 62 focal liver lesions in 58 cirrhotic patients were studied by ultrasonography; 12 of these focal lesions were documented to be regenerating lesions by echo-guided fine-needle biopsy. During an average follow-up period of 10.2 months (range 3-22 months), hepatocellular carcinoma was subsequen...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536913

    authors: Rapaccini GL,Pompili M,Caturelli E,Anti M,Aliotta A,Cedrone A,Amadei E,Grattagliano A,Squillante MM,Rabitti C

    更新日期:1990-04-01 00:00:00

  • Gallbladder kinetics in obese patients. Effect of a regular meal and low-calorie meal.

    abstract::Gallbladder contractility has been studied in 21 obese patients (greater than 130% ideal weight) and 30 nonobese subjects before and at regular intervals after the administration of a regular solid-liquid meal, and after a low-calorie, low-fat meal used conventionally for weight-loss purposes (Modifast). Gallbladder v...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536623

    authors: Marzio L,Capone F,Neri M,Mezzetti A,De Angelis C,Cuccurullo F

    更新日期:1988-01-01 00:00:00

  • Intestinal disaccharidases assessed in congenital asucrasia by differential urinary disaccharide excretion.

    abstract::A patient with congenital asucrasia was investigated using in vivo differential urinary disaccharide excretion. Impaired hydrolysis of sucrose and isomaltose, but normal lactase activity, were demonstrated and confirmed by in vitro estimation. The technique of differential disaccharide excretion can now be used to ass...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536167

    authors: Maxton DG,Catt SD,Menzies IS

    更新日期:1989-01-01 00:00:00

  • Effect of mosapride combined with esomeprazole improves esophageal peristaltic function in patients with gastroesophageal reflux disease: a study using high resolution manometry.

    abstract:BACKGROUND:Whether addition of prokinetics to proton pump inhibitors improves esophageal peristalsis and symptoms in patients with gastroesophageal reflux disease (GERD) remains unknown. AIM:We evaluated the effect of mosapride, a 5-HT4 agonist, and PPI cotherapy in patients with GERD on esophageal motility using high...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10620-012-2430-y

    authors: Cho YK,Choi MG,Park EY,Lim CH,Kim JS,Park JM,Lee IS,Kim SW,Choi KY

    更新日期:2013-04-01 00:00:00

  • Sucrase-Isomaltase Deficiency as a Potential Masquerader in Irritable Bowel Syndrome.

    abstract:BACKGROUND:Patients with irritable bowel syndrome (IBS) frequently have meal-related symptoms and can recognize specific trigger foods. Lactose intolerance is a well-established carbohydrate malabsorption syndrome that causes symptoms similar to IBS such as bloating, abdominal pain, and diarrhea. However, the prevalenc...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-019-05780-7

    authors: Kim SB,Calmet FH,Garrido J,Garcia-Buitrago MT,Moshiree B

    更新日期:2020-02-01 00:00:00

  • Smoking and male gender rather than CagA protein are associated with increased risk for duodenal ulcer in Helicobacter pylori-infected patients in Taiwan.

    abstract::The aim of this study was to examine the seroprevalence of antibody to CagA antigen, as well as other major H. pylori antigens by Western blot in H. pylori-infected subjects with endoscopically normal mucosa (N = 54) and duodenal ulcer (N = 51). The role of the host and environmental factors was also evaluated. There ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026634721351

    authors: Chen TS,Chang FY,Lee SD

    更新日期:1999-10-01 00:00:00