Improvement of fecal fat excretion after addition of omeprazole to pancrease in cystic fibrosis is related to residual exocrine function of the pancreas.

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:There is a wide choice of fecal occult blood tests (FOBTs) for colorectal cancer screening. GOAL:To highlight the issues applicable when choosing a FOBT, in particular which FOBT is best suited to the range of screening scenarios. Four scenarios characterize the constraints and expectations of screening pro...

journal_title：Digestive diseases and sciences

authors： Young GP,Symonds EL,Allison JE,Cole SR,Fraser CG,Halloran SP,Kuipers EJ,Seaman HE

更新日期：2015-03-01 00:00:00

abstract：:The objective of this work was to study the influence of insulin resistance and adipokines on the grade of steatosis in patients with NAFLD (nonalcoholic fatty liver disease) diagnosed by liver biopsy. A sample of 24 NAFLD patients was analyzed in a cross-sectional study. All patients with a two-week weight-stabilizat...

journal_title：Digestive diseases and sciences

authors： Aller R,de Luis DA,Fernandez L,Calle F,Velayos B,Olcoz JL,Izaola O,Sagrado MG,Conde R,Gonzalez JM

更新日期：2008-04-01 00:00:00

abstract：:We have used single-strand conformational polymorphism (SSCP) and heteroduplex analysis to examine DNA from 50 colorectal carcinoma patients coming from families meeting the Amsterdam criteria for hereditary nonpolyposis colorectal cancer (HNPCC) or having developed colorectal carcinoma at age 45 or younger. We identi...

journal_title：Digestive diseases and sciences

authors： Lin X,Choi JH,Lynch P,Xi L,Wu E,Frazier ML

更新日期：1999-03-01 00:00:00

abstract：:Basal gastric acid output was analyzed prospectively in 110 patients with endoscopically documented duodenal ulcer disease to determine the frequency of gastric acid hypersecretion in patients with bleeding versus nonbleeding ulcers. Thirty-eight patients with stigmata of an actively or recently bleeding duodenal ulce...

journal_title：Digestive diseases and sciences

authors： Collen MJ,Kalloo AN,Sheridan MJ

更新日期：1993-02-01 00:00:00

abstract：:The purpose of this study was to evaluate the inhibitory activity of selenium-enriched probiotics against pathogenic Escherichia coli (E. coli) in vitro and in vivo. Escherichia coli was co-cultured in vitro with each probiotic strain individually, and a mixture of the four strains and its population was counted at va...

journal_title：Digestive diseases and sciences

authors： Yang J,Huang K,Qin S,Wu X,Zhao Z,Chen F

更新日期：2009-02-01 00:00:00

abstract：:Our aim was to compare standard liver function tests (serum bilirubin, serum albumin and prothrombin concentration), with lidocaine and monoethylglycinexylidide pharmacokinetic parameters, after oral lidocaine administration, to assess hepatic function of cirrhotic individuals. Twenty-one consecutive cirrhotic patient...

journal_title：Digestive diseases and sciences

authors： Muñoz AE,Miguez C,Rubio M,Bartellini M,Levi D,Podestá A,Niselman V,Terg R

更新日期：1999-04-01 00:00:00

abstract：:There continues to be disagreement regarding the effects of ethanol on gastric emptying. This study was designed to assess different degrees of ethanol exposure on gastric emptying. Scintigraphic gastric emptying studies were performed in healthy adult cats and the half time (t1/2) of gastric emptying was obtained fro...

journal_title：Digestive diseases and sciences

authors： Willson CA,Bushnell D,Keshavarzian A

更新日期：1990-04-01 00:00:00

abstract：:A gangliocytic paraganglioma (GP) is an extremely rare neurogenic tumor nearly located in the second portion of the duodenum and has been regarded as benign. We report a case of duodenal GP in a 53-year-old man. The GP arose in the second portion of the duodenum and was shown by histological examination to consist of ...

journal_title：Digestive diseases and sciences

authors： Morita T,Tamura S,Yokoyama Y,Onishi T,Kuratani Y,Mizuta H,Onishi S

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The proliferation of cholangiocarcinoma cells is suppressed in cell culture by nonsteroidal antiinflammatory drugs (NSAIDs) through the inhibition of cyclo-oxygenase-2 enzyme and also by statins which decrease the production of mediators of the cell cycle. AIMS:To investigate whether there is an inverse ass...

journal_title：Digestive diseases and sciences

authors： Burr NE,Talboys RJ,Savva S,Clark A,Phillips M,Metcalfe M,Dennison A,Robinson R,Lewis MP,Rhodes M,Rushbrook S,Hart AR

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The relationship of gastric cancer to the presence of interleukin-8 (IL-8) 251 T/A has been reported with conflicting results. AIM:To further explore the association of IL-8 251 allele polymorphism with gastric cancer susceptibility. METHODS:We performed an extensive search of relevant studies and carried ...

journal_title：Digestive diseases and sciences

authors： Wang J,Pan HF,Hu YT,Zhu Y,He Q

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:The headword "overlap syndromes" of liver diseases includes the coexistence of autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis. These syndromes often represent a diagnostic and therapeutic challenge for hepatologists; it remains unclear whether these overlap syndromes form distinct ...

journal_title：Digestive diseases and sciences

authors： Durazzo M,Premoli A,Paschetta E,Belci P,Spandre M,Bo S

更新日期：2013-02-01 00:00:00

abstract：:This study was designed to evaluate the role of 111In-labeled leukocyte imaging and fecal excretion in the assessment of inflammatory bowel disease. We compared these tests to various indices of disease activity in Crohn's disease, to Truelove's grading in ulcerative colitis, and to endoscopy, x-ray, and pathology in ...

journal_title：Digestive diseases and sciences

authors： Leddin DJ,Paterson WG,DaCosta LR,Dinda PK,Depew WT,Markotich J,McKaigney JP,Groll A,Beck IT

更新日期：1987-04-01 00:00:00

abstract：:In a double-blind, randomized crossover study, the hypotheses were tested that more powerful inhibition of gastric acid secretion by adjuvant omeprazole further improves the efficacy of pancreatic enzyme replacement therapy compared to adjuvant cimetidine and that excluding the influence of pH-related factors, by virt...

journal_title：Digestive diseases and sciences

authors： Bruno MJ,Rauws EA,Hoek FJ,Tytgat GN

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The principle of treating-to-target has been successfully applied to many diseases with significant improvement in patient care and as a useful guidance for healthcare providers. Appreciation of the central role for arterial vasodilatation in the pathogenesis of hepatorenal syndrome (HRS) has led to routine ...

journal_title：Digestive diseases and sciences

authors： Cai CX,Maddukuri G,Jaipaul N,Zhang Z

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the potential for pancreatic calcification in autoimmune pancreatitis by investigating osteopontin and CD44 expression. METHODS:Human pancreatic tissues in normal pancreas, chronic pancreatitis, and autoimmune pancreatitis were obtained from the surgical specime...

journal_title：Digestive diseases and sciences

authors： Takada H,Nakazawa T,Ohara H,Ando T,Hayashi K,Naito I,Okumura F,Tanaka H,Yamada T,Takahashi S,Joh T

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Percutaneous endoscopic gastrostomy (PEG) is a commonly performed procedure for patients with severe dysphagia leading to malnutrition. Improved knowledge of risk factors for PEG-related complications might decrease patient discomfort and healthcare costs. AIM:The aim of the present study was to investigate...

journal_title：Digestive diseases and sciences

authors： Lee SP,Lee KN,Lee OY,Lee HL,Jun DW,Yoon BC,Choi HS,Kim SH

更新日期：2014-01-01 00:00:00

abstract：:Neurotensin-like immunoreactivity (NTLI) is released into the circulation following a meal. However, the factors influencing its degradation and metabolism are uncertain, but it is presumed that the kidneys and liver are involved. This study has determined the release of NTLI after a liquid fat meal (200 ml 20% Intral...

journal_title：Digestive diseases and sciences

authors： Eaves ER,Hansky J

更新日期：1987-01-01 00:00:00

abstract：:A prospective study was performed in 17 patients with achalasia of the esophagus determining the manometric characteristics of the gastroesophageal sphincter, correlating it with histological analysis by biopsies taken during surgery at the distal narrowed segment of the esophagus, at the location of the sphincter. Th...

journal_title：Digestive diseases and sciences

authors： Csendes A,Smok G,Braghetto I,Ramirez C,Velasco N,Henriquez A

更新日期：1985-10-01 00:00:00

abstract：:The study was undertaken to examine regional differences in the concentrations of five regulatory peptides in the human colonic mucosa. Biopsies were obtained during routine colonoscopy from 33 patients whose colonic mucosa was macroscopically and histologically normal. Regulatory peptides were extracted, and measured...

journal_title：Digestive diseases and sciences

authors： Calam J,Ghatei MA,Domin J,Adrian TE,Myszor M,Gupta S,Tait C,Bloom SR

更新日期：1989-08-01 00:00:00

abstract：:The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial he...

journal_title：Digestive diseases and sciences

authors： Assy N,Hussein O,Khalil A,Luder A,Szvalb S,Paizi M,Spira G

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and diabetes are risk factors for advanced alcoholic liver disease, and both are components of the metabolic syndrome. We aimed to assess the prevalence of metabolic syndrome and its components in a contemporary US cohort of adults with alcoholic liver disease and compare it to a historic co...

journal_title：Digestive diseases and sciences

authors： Singh A,Amin H,Garg R,Gupta M,Lopez R,Alkhouri N,MCCullough A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:IL-1β is a cytokine involved in mediating epithelial barrier dysfunction in the gut. It is known that IL-1β mediates activation of non-muscle myosin light chain kinase in epithelial cells, but the precise mechanism by which epithelial barrier dysfunction is induced by IL-1β is not understood. METHODS AND RE...

journal_title：Digestive diseases and sciences

authors： Haines RJ,Beard RS Jr,Chen L,Eitnier RA,Wu MH

更新日期：2016-08-01 00:00:00

abstract：:Factors and mechanisms involved in esophageal mucosal injury and repair are not well known. The aim of this study was to assess the effects of growth factors and prostaglandins on esophageal mucosal cell repair activities. Rabbit esophageal cells were isolated, cultured, and exposed to different growth factors and pro...

journal_title：Digestive diseases and sciences

authors： Jimenez P,Lanas A,Piazuelo E,Esteva F

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:An imbalance in gut microbiota seems to contribute to the development of chronic inflammatory disorders of the gastrointestinal tract, such as ulcerative colitis (UC). Although it has been suggested that probiotic supplementation is an effective approach to colitis, its effects on intestinal flora and on muc...

journal_title：Digestive diseases and sciences

authors： D'Incà R,Barollo M,Scarpa M,Grillo AR,Brun P,Vettorato MG,Castagliuolo I,Sturniolo GC

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Eosinophilic gastroenteritis (EOGE) is a rare idiopathic disease characterized by eosinophil-predominant inflammation of the stomach and/or intestines. Our aims are to determine the epidemiology, clinical features and outcomes of EOGE cases in a tertiary-care hospital. METHODS:Retrospective cohort study of ...

journal_title：Digestive diseases and sciences

authors： Alhmoud T,Hanson JA,Parasher G

更新日期：2016-09-01 00:00:00

abstract：:Tramadol and morphine were compared for treatment of severe chronic pancreatitis pain and their interaction with gut motor function. Oral tramadol or morphine doses were titrated double-blinded and randomized for five days in 25 patients and pain, side effects, bowel function, orocecal and colonic transit, anal restin...

journal_title：Digestive diseases and sciences

authors： Wilder-Smith CH,Hill L,Osler W,O'Keefe S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown. AIMS:Th...

journal_title：Digestive diseases and sciences

authors： Im JP,Ye BD,Kim JM,Jung HC,Song IS,Kim JS

更新日期：2011-08-01 00:00:00

abstract：:The original version of the article unfortunately contained an error in the unit used for 'Distance of propagation'. The distance of propagation should be in the unit 'cm' rather than 'mm' throughout the manuscript. ...

journal_title：Digestive diseases and sciences

authors： Jaung R,Varghese C,Lin AY,Paskaranandavadivel N,Du P,Rowbotham D,Dinning P,O'Grady G,Bissett I

更新日期：2020-08-08 00:00:00