Abstract：
:Nonalcoholic steatohepatitis is the fastest-growing indication for the liver transplant and a leading cause of hepatocellular carcinoma among patients listed for liver transplantation in the USA. Post-transplant nonalcoholic hepatic steatosis and steatohepatitis are frequent complications of liver transplantation. Nonalcoholic steatohepatitis poses a significant challenge in both pre- and post-transplant period due to its association with metabolic syndrome, coronary artery disease, chronic kidney disease, and obstructive sleep apnea. While optimal therapy is not yet available in the post-liver transplant setting, lifestyle interventions continue to remain as the mainstay of therapy for post-transplant nonalcoholic steatohepatitis. Early recognition with protocol biopsies and noninvasive modalities, along with modification of known risk factors, are the most effective methods to curtail the progression of nonalcoholic steatohepatitis in the absence of FDA-approved pharmacologic therapy.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Samji NS,Verma R,Keri KC,Singal AK,Ahmed A,Rinella M,Bernstein D,Abdelmalek MF,Satapathy SKdoi
10.1007/s10620-019-05716-1subject
Has Abstractpub_date
2019-12-01 00:00:00pages
3413-3430issue
12eissn
0163-2116issn
1573-2568pii
10.1007/s10620-019-05716-1journal_volume
64pub_type
杂志文章,评审abstract：:Twelve partially gastrectomized subjects who have consecutively undergone total biliary diversion for severe bilious vomiting were studied before and after operation in order to assess the effects of surgery on gastric histology and enterogastric reflux. Before and six months after operation, the following protocol wa...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536682
更新日期：1988-10-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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doi：10.1007/BF01297143
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doi：10.1007/s10620-006-9657-4
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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doi：10.1007/BF01299863
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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更新日期：1979-02-01 00:00:00
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journal_title：Digestive diseases and sciences
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doi：10.1007/BF01296568
更新日期：1992-08-01 00:00:00
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更新日期：2011-04-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296291
更新日期：1987-04-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018895207333
更新日期：1997-10-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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pub_type： 杂志文章,随机对照试验
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-008-0595-1
更新日期：2009-10-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308196
更新日期：1985-02-01 00:00:00
