Cytological screening for Barrett's esophagus using a prototype flexible mesh catheter.

Abstract:

:The current cost of endoscopically screening patients with gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) is considerable. A nonendoscopic device that allows for screening of these patients would offer significant cost savings. This pilot study evaluates the utility of cytologically diagnosing BE using a prototype flexible mesh catheter. Patients with known BE undergoing indicated surveillance endoscopy were enrolled in the study. Cytology specimens were obtained using a prototype flexible catheter and were evaluated for the presence of glandular cells, goblet cells, squamous cells, inflammation, and dysplasia. Eleven patients with BE were enrolled in the study. None of the patients experienced complications. Specimens from eight patients (73%) were adequate for evaluation and seven of these patients (87.5%) had goblet cells diagnostic for BE. In conclusion, flexible mesh catheters potentially offer a sensitive, inexpensive, and minimally invasive approach to evaluating patients with GERD and BE.

journal_name

Dig Dis Sci

authors

Rader AE,Faigel DO,Ditomasso J,Magaret N,Burm M,Fennerty MB

doi

10.1023/a:1012771328187

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

2681-6

issue

12

eissn

0163-2116

issn

1573-2568

journal_volume

46

pub_type

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