Prevalence of gastroesophageal reflux disease symptoms and uninvestigated dyspepsia in Korea: a population-based study.

abstract：BACKGROUND:Individuals with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC) compared with the general population. Previous studies show this risk is strongly associated with dysplasia, extent of disease, duration of disease, and degree of inflammation, while chemoprevention ...

journal_title：Digestive diseases and sciences

authors： Tang J,Sharif O,Pai C,Silverman AL

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

journal_title：Digestive diseases and sciences

authors： Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The use of proton pump inhibitors (PPIs) is thought to increase the incidence of microscopic colitis (MC), although the exact mechanisms are not fully understood. Increased infiltration of intraepithelial lymphocytes (IELs) is a pathologic finding of MC (including collagenous or lymphocytic colitis). AIMS:W...

journal_title：Digestive diseases and sciences

authors： Yu YH,Han DS,Choi EY,Park HS,Jeong JY,Eun CS,Oh YH,Pyo JY

更新日期：2012-10-01 00:00:00

abstract：:Viral dynamic studies in chronic hepatitis C virus (HCV) infection indicate a significantly shortened survival of virus-infected cells. Since at the steady state of chronic viral infection, the rate of infected cell elimination equals new cell regeneration, this would imply a high rate of hepatocyte turnover in chroni...

journal_title：Digestive diseases and sciences

authors： Lake-Bakaar G,Mazzoccoli V,Ruffini L

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Both colorectal neoplasms and atherosclerosis can be induced by common visceral fat accumulation. However, the association between these diseases at the advanced stage, colorectal cancer and cardiovascular/cerebrovascular diseases, has not been elucidated. AIMS:This study aimed to investigate the associatio...

journal_title：Digestive diseases and sciences

authors： Yamaji Y,Yasunaga H,Hirata Y,Yamada A,Yoshida S,Horiguchi H,Fushimi K,Koike K

更新日期：2016-06-01 00:00:00

abstract：:Using northern blot analysis and immunohistochemistry, we assessed the expression and distribution of human epidermal growth factor receptor-1 (HER-1), HER-2, and HER-3 in pancreatic tissues obtained from patients with acute pancreatitis (AP). Overall, HER-1, HER-2, and HER-3 mRNA levels were similar in the normal pan...

journal_title：Digestive diseases and sciences

authors： Ebert M,Friess H,Büchler MW,Korc M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Despite national campaigns and other efforts to improve colorectal cancer (CRC) screening, participation rates remain below targets set by expert panels. We hypothesized that availability and practice patterns of healthcare providers may contribute to this gap. METHOD:Using data of the Medical Expenditure P...

journal_title：Digestive diseases and sciences

authors： Gawron AJ,Staub J,Bielefeldt K

更新日期：2021-01-01 00:00:00

abstract：:Endoscopic biopsies are being increasingly utilized to investigate cytokine profiles in normal and diseased intestine. To evaluate the adequacy of mucosal biopsies as a source of cytokine-specific mRNA, we measured their content of interleukin-1 beta (IL-1 beta) and interleukin-2 (IL-2) mRNA by reverse transcription-p...

journal_title：Digestive diseases and sciences

authors： Fukushima K,West G,Fiocchi C

更新日期：1995-07-01 00:00:00

abstract：:If an effective hepatic assist system existed, it could serve as a bridge to transplantation. Most of the patients waiting for liver transplantation have chronic liver insufficiency but are not in hepatic coma. Various hepatic assist systems have been used to salvage patients with acute liver insufficiency. Most attem...

journal_title：Digestive diseases and sciences

authors： Takahashi T,Malchesky PS,Nosé Y

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a common disease with intestinal dysmotility, whose mechanism remains elusive. TMEM16A is a calcium-activated chloride channel (CaCC) involved in intestinal slow-wave generation. AIMS:To investigate whether TMEM16A is involved in colonic dysmotility in IBS. METHODS:A rat m...

journal_title：Digestive diseases and sciences

authors： Lin MJ,Yu BP

更新日期：2018-12-01 00:00:00

abstract：:We present the case of a 60-year-old male patient, who had several episodes of melena during the last years. One month ago he had a new episode of digestive bleeding, and an endoscopic study was performed that showed at 35 cm from the dental arcade a polypoid, pedunculated lesion, with a diameter of 5 cm and a submuco...

journal_title：Digestive diseases and sciences

authors： Bosch O,González Campos C,Jurado A,Guijo I,Miro C,Renedo G,Porres JC

更新日期：1994-12-01 00:00:00

abstract：:Nitric oxide appears to play an important role in maintaining gastric mucosal integrity. This study aimed to investigate whether a nitric oxide donor (sodium nitroprusside) or stimulation of endogenous nitric oxide synthesis (with acetylcholine) protects against gastric ischemia-reperfusion injury. Rats were subjected...

journal_title：Digestive diseases and sciences

authors： Andrews FJ,Malcontenti-Wilson C,O'Brien PE

更新日期：1994-02-01 00:00:00

abstract：:Two baboons receiving intramuscular injections of ferric nitrilotriacetate over a two-year period were compared with two control baboons. The results indicate that in iron-overloaded animals: liver iron excess was major (maximal liver iron concentration values of 42 mumol/100 mg dry weight for both animals vs 1.3 +/- ...

journal_title：Digestive diseases and sciences

authors： Brissot P,Farjanel J,Bourel D,Campion JP,Guillouzo A,Rattner A,Deugnier Y,Desvergne B,Ferrand B,Simon M

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:Few studies compare gastroesophageal reflux (GER) parameters of cystic fibrosis (CF) children and symptomatic non-CF children. We aimed to compare the impedance-pH (IMP-pH) parameters for these two groups and to test the hypothesis that prolonged acid exposure in CF patients is due to delayed chemical cleara...

journal_title：Digestive diseases and sciences

authors： Woodley FW,Machado RS,Hayes D Jr,Di Lorenzo C,Kaul A,Skaggs B,McCoy K,Patel A,Mousa H

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:Guidelines recommend routine invasive screening for Helicobacter pylori in patients with peptic ulcer hemorrhage (PUH). However, compliance with screening remains suboptimal. The aim of this study was to determine if a simplified approach based on noninvasive screening is cost effective in PUH. RESULTS:In the ...

journal_title：Digestive diseases and sciences

authors： Atreja A,Fu AZ,Sanaka MR,Vargo JJ

更新日期：2010-05-01 00:00:00

abstract：:The major heat shock protein, HSP70, is known to be involved in cytoprotection against environmental stresses mediated by their function as a "molecular chaperone." However, the influence of HSP70 on gastric mucosal healing under physical stimulation or stress is not completely understood. Rat gastric mucosal cells (R...

journal_title：Digestive diseases and sciences

authors： Odashima M,Otaka M,Matsuhashi T,Jin M,Horikawa Y,Ohba R,Itoh H,Watanabe S

更新日期：2007-11-01 00:00:00

abstract：:Up to 60% of patients with IBS have lowered perception thresholds in the rectum to balloon distension. The current study sought to test the hypothesis that IBS patients with normal perception thresholds in the rectum show hypersensitivity of afferent pathways in the sigmoid colon. Eleven healthy normal subjects and ei...

journal_title：Digestive diseases and sciences

authors： Lembo T,Munakata J,Naliboff B,Fullerton S,Mayer EA

更新日期：1997-06-01 00:00:00

abstract：:The hydrogen (H2) lactose breath test (BT) is a test commonly used for the diagnosis of hypolactasia. However, its sensitivity is not always good. In the last few years, the new Quick Lactase Test (QLT) has been developed for endoscopic diagnosis of adult-type hypolactasia. The aim of this study was to compare the eff...

journal_title：Digestive diseases and sciences

authors： Ojetti V,La Mura R,Zocco MA,Cesaro P,De Masi E,La Mazza A,Cammarota G,Gasbarrini G,Gasbarrini A

更新日期：2008-06-01 00:00:00

abstract：:These studies were done to determine the effects of fluoride (F) on the structure and function of the canine gastric mucosa and the possible protective effects of 16,16-dimethyl-prostaglandin E2 (dmPGE2). A portion of the stomach with its vascular supply intact was mounted in a two-compartment chamber, one side of whi...

journal_title：Digestive diseases and sciences

authors： Whitford GM,Pashley DH,Garman RH

更新日期：1997-10-01 00:00:00

abstract：:Our aim was to investigate the role of renal colic, a clinical condition characterized by excruciating pain, in the etiopathogenesis of irritable bowel syndrome (IBS). Two groups of patients were enrolled in the study. Group I consisted of 59 patients (33 male and 26 female) with a median age of 41.9 (18 to 58) years....

journal_title：Digestive diseases and sciences

authors： Erdem E,Akbay E,Sezgin O,Doruk E,Canpolat B,Cayan S

更新日期：2005-03-01 00:00:00

abstract：:Diamine oxidase (DAO) is an enzyme whose low plasma values are enhanced by an intravenous injection of heparin, which releases the enzyme from the enterocytes of the villous tips. In 20 normal controls and 15 untreated subjects affected with an overt malabsorption syndrome and subtotal atrophy shown by Crosby jejunal ...

journal_title：Digestive diseases and sciences

authors： D'Agostino L,Ciacci C,Daniele B,Barone MV,Sollazzo R,Mazzacca G

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Liver metastasis is an indicator of unfavorable responses to immunotherapy in colorectal cancer patients. However, the difference of immune microenvironment between primary tumors and liver metastases has not been well understood. PATIENTS AND METHODS:Fifty-four colon cancer with liver metastasis patients w...

journal_title：Digestive diseases and sciences

authors： Zhou SN,Pan WT,Pan MX,Luo QY,Zhang L,Lin JZ,Zhao YJ,Yan XL,Yuan LP,Zhang YX,Yang DJ,Qiu MZ

更新日期：2020-03-19 00:00:00

abstract：:After gastrectomy, Roux-Y limb reconstruction leads to duodenojejunal motor disturbances. Because motilin and pancreatic polypeptide (PP) play a role in the regulation of digestive motility, their plasma concentrations were determined in rats after Roux-Y gastrectomy. Three months after a distal Roux-Y gastrectomy, co...

journal_title：Digestive diseases and sciences

authors： Le Blanc-Louvry I,Ducrotte P,Chayvialle JA,Coquerel A,Michot F,Ténière P

更新日期：2000-08-01 00:00:00

abstract：:Endoscopic papillary balloon dilatation (EPBD) has been recently used in conjunction with endoscopic sphincterotomy (EST) for the removal of common bile duct (CBD) stones. The present study was aimed at assessing the safety and outcome of sequential EPBD following EST for CBD stones. A total of 74 patients (43 females...

journal_title：Digestive diseases and sciences

authors： Kochhar R,Dutta U,Shukla R,Nagi B,Singh K,Wig JD

更新日期：2009-07-01 00:00:00

abstract：:It has previously been shown that mucosal nitric oxide synthase (NOS) is involved in acid-induced duodenal mucosal alkaline secretion. The primary aim of the present study was to elucidate which isoform of NOS is responsible in rats. Immunohistochemistry showed that inducible NOS (iNOS) was constitutively expressed in...

journal_title：Digestive diseases and sciences

authors： Holm M,Powell T,Casselbrant A,Johansson B,Fändriks L

更新日期：2001-08-01 00:00:00

abstract：UNLABELLED:The lactulose breath test (LBT) and gastroenterocolonic scintigraphy (GECS) can both be used to measure orocecal transit time (OCTT). The aims of this study were (1) to measure OCTT by LBT and GECS and (2) to determine whether lactulose alters orocecal transit. METHODS:Eight normal subjects underwent simult...

journal_title：Digestive diseases and sciences

authors： Miller MA,Parkman HP,Urbain JL,Brown KL,Donahue DJ,Knight LC,Maurer AH,Fisher RS

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The nature and outcomes of infection among patients with cirrhosis in safety-net hospitals are not well described. We aimed to characterize the rate of and risk factors for infection, both present on admission and nosocomial, in this unique population. We hypothesized that infections would be associ...

journal_title：Digestive diseases and sciences

authors： Fricker ZP,Mukthinuthalapati VVPK,Akinyeye S,Chalasani N,Attar BM,Balakrishnan M,Ghabril M,Long MT

更新日期：2021-01-01 00:00:00

abstract：:In the early 1970s an increased prevalence of gallstones was reported in adults and children with immunoglobulin deficiency. As the advent of ultrasonography has largely changed the diagnostic approach to gallstones, we have reevaluated the prevalence of cholelithiasis in a group including 37 patients with common vari...

journal_title：Digestive diseases and sciences

authors： De Santis A,Paganelli R,Stefanoni R,Di Sabatino A,Angelico M

更新日期：1990-06-01 00:00:00

abstract：:The evaluation of agents potentially accelerating gastric emptying in gastric stasis syndromes is time-consuming. Since a previous study showed that emptying is slowed after antecedent fat ingestion and intravenous cisapride abolishes this effect, we investigated whether emptying delayed by fat incorporated into a mea...

journal_title：Digestive diseases and sciences

authors： Stacher G,Granser GV,Bergmann H,Kugi A,Stacher-Janotta G,Höbart J

更新日期：1991-09-01 00:00:00

abstract：:In Japanese healthy CYP2C19 extensive metabolizers, rabeprazole 10 mg shows a faster onset of action and stronger inhibition of acid secretion than does omeprazole 20 mg on the first 3 days of administration. We evaluated gastric ulcer improvement after 1 week's treatment with rabeprazole or omeprazole in relation to ...

journal_title：Digestive diseases and sciences

authors： Ando T,Ishikawa T,Kokura S,Naito Y,Yoshida N,Yoshikawa T

更新日期：2008-04-01 00:00:00